134: The Science of Gene Editing & Treating Blindness

For the first time ever we’ve used CRISPR  to edit someone’s genes INSIDE THEIR BODY! So far we’ve been able to reverse some effects of rare genetic eye disease that results in blindness, and this is only the beginning!You can WATCH the podcast over on our YouTube channel:http://youtube.com/SciGuys Help keep the show running by supporting us on Patreon!http://patreon.com/sciguys If you'd like to see more of us, follow our socials!Facebookhttp://facebook.com/SciGuysPodTwitterhttp://twitter.com/SciGuysPodInstagramhttp://instagram.com/SciGuysPodFollow the SCI GUYS@notcorry / @jampkin / @lukecutforth References & Further Reading https://medlineplus.gov/genetics/condition/leber-congenital-amaurosis/ https://rarediseases.info.nih.gov/diseases/634/leber-congenital-amaurosis https://luxturna.com Gene Therapy https://www.nature.com/articles/d41586-018-06195-6 https://www.nature.com/articles/s41587-020-0493-4 https://www.nature.com/articles/s41573-019-0012-9 The EDIT-101 Trial https://clinicaltrials.gov/ct2/show/study/NCT03872479 https://www.nature.com/articles/s41591-018-0327-9 https://text.npr.org/2021/09/29/1040879179/vision-loss-crispr-treatment https://www.nature.com/articles/d41586-020-00655-8https://www.nature.com/articles/d41586-020-00655-8 https://jamanetwork.com/journals/jama/fullarticle/2764428https://jamanetwork.com/journals/jama/fullarticle/2764428