#18 When long-term stability on a Crohn's drug meets a curveball: an IBD patient's story episode artwork

EPISODE · Oct 23, 2025 · 45 MIN

#18 When long-term stability on a Crohn's drug meets a curveball: an IBD patient's story

from Wrestling the Octopus (IBD)

Send us Fan MailMeet Olie Bosley.Olie is an IT and cybersecurity expert from Oxford, UK who has suffered from Crohn's disease symptoms for nearly 30 years.We invited Olie to join us for this episode as he has an important story to share: what happens when the drug that has kept you well for so long - in his case Humira (adalimumab) - without notice causes you side effects that mean you need to stop taking it. Olie speaks with candour to Nigel and me on the practical and psychological challenges this brings a patient who hitherto had well controlled inflammatory bowel disease. His story is a testament to resilience, advocating for oneself and the importance on inter-department communication when treating IBD patients.🔍 What You’ll LearnHow a childhood injury may have shaped Olie’s health trajectoryThe possible link between seronegative arthritis and Crohn’s diseaseWhy Olie delayed his first colonoscopy... and what changed his mindThe impact of NSAIDs on gut health and Crohn’s progressionOlie’s experience with methotrexate, azathioprine, Humira, infliximab, ustekinumab and RinvoqThe overlooked reality of bile acid malabsorption after TI surgeryHow UVB therapy helped resolve a Humira-related skin reactionThe importance of communication between rheumatology, dermatology and IBD teamsYou can follow Olie Bosley on X (@Olski).Follow Rachel at @bottomlineibdFollow Nigel at @crohnoid

Send us Fan Mail Meet Olie Bosley. Olie is an IT and cybersecurity expert from Oxford, UK who has suffered from Crohn's disease symptoms for nearly 30 years. We invited Olie to join us for this episode as he has an important story to share: what happens when the drug that has kept you well for so long - in his case Humira (adalimumab) - without notice causes you side effects that mean you need to stop taking it. Olie speaks with candour to Nigel and me on the practical and psychological...

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#18 When long-term stability on a Crohn's drug meets a curveball: an IBD patient's story

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This episode is 45 minutes long.

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This episode was published on October 23, 2025.

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Send us Fan MailMeet Olie Bosley.Olie is an IT and cybersecurity expert from Oxford, UK who has suffered from Crohn's disease symptoms for nearly 30 years.We invited Olie to join us for this episode as he has an important story to share: what...

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