#39 - Why muscle glycogen is important with Dr Niels Ørtenblad

Dr Glenn McConell chats with Professor Niels Ørtenblad from the University of Southern Denmark. He is an expert on muscle glycogen. We discussed the history of muscle glycogen and exercise research, the effect of diet and exercise training on muscle glycogen levels and use, the distribution and use of muscle glycogen within different muscle fibre compartments, unusual to fully deplete muscle glycogen during exerciseand the potential role of muscle glycogen depletion in muscle fatigue. Very interesting stuff. Niel’s Twitter: @nortenblad.0:00. Introduction and Niels background6:15. History of the study of muscle glycogen and exercise9:15. Muscle glycogen and lactate11:38. Correlation does not imply causation12:10. Fat use during exercise is less efficient than CHO14:12. Diet, muscle glycogen and exercise performance16:00. 1920s and 1930s a golden age of exercise physiology18:20. Bengt Saltin undertook 30,000 muscle biopsies20:00. Effect of intensity and duration on muscle glycogen use21:20. Diet and muscle glycogen use23:15. High glycogen results in high glycogen use during ex24:33. Exercise training results in higher muscle glycogen levels25:51. Why “waste” muscle glycogen when it’s high27:30. Energy faster from carbohydrate than from fat28:40. Carbohydrate ingestion and muscle glycogen use32:05. Glycogen particles / location within the muscle and fatigue36:51. Calcium release, glycogen levels and fatigue40:20. Unusual to fully deplete muscle glycogen during exercise42:40. Muscle glycogen depletion in different muscle fibers45:30. How muscle glycogen effects muscle calcium release49:55. How muscle glycogen effects muscle calcium uptake51:53. Muscle glycogen and excitation-contraction coupling57:18. Diabetes and muscle glycogen use during exercise58:17. Muscle glycogen use during exercise in male vs females59:24. Need really high muscle glycogen?/increases body weight1:04:16. Studies he’s excited to do1:05:38. Should try to disprove your hypothesis1:08:20. Takeaway messages1:09:30. Glycogen particle size with glycogen use/diet1:13:40. Outro (9 secs)Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).Connect with Inside Exercise and Glenn McConell at:Twitter: @Inside_exercise and @GlennMcConell1Instagram: insideexerciseFacebook: Glenn McConellLinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460ResearchGate: Glenn McConellEmail: [email protected] Subscribe to Inside exercise:Spotify: shorturl.at/tyGHLApple Podcasts: shorturl.at/oFQRUYouTube: https://www.youtube.com/@insideexerciseAnchor: https://anchor.fm/insideexerciseGoogle Podcasts: shorturl.at/bfhHIAnchor: https://anchor.fm/insideexercisePodcast Addict: https://podcastaddict.com/podcast/4025218