#62 - Interaction of exercise with muscle circadian clocks with Dr Karyn Esser

Dr Glenn McConell chats with Professor Karyn Esser from the University of Florida, USA. She is an authority on circadian biology. We discuss whether exercise affects muscle circadian clocks and whether muscle clocks affect exercise. What is the best time to exercise and to eat etc. Also the effects of jet lag and shift work and how to best manage these. A very interesting chat. Karyn’s Twitter: @kaesser.0:00. Introduction2:30. How Karyn got into exercise research.4:40. She was “picked up” by Arnold Schwarzenegger5:32. Her muscle hypertrophy work7:00. What are circadian rhythms?9:40. Jet lag11:10. How central clocks and peripheral clocks interact14:16. Social jet lag15:45. Timing of running rodents because nocturnal 16:47. Best to wear sunglasses when jet lagged?17:54. Melatonin19:40. Muscle clocks prepare the muscle26:54. Sleep onset and dark onset are not necessarily correlated30:23. Time of day and exercise performance34:10. Running in the morning can shift muscle clocks forward37:00. Train at the time of the race39:25. Contracting muscle cells and circadian rhythms41:00. Timing of eating and muscle circadian rhythms43:00. How long does it take to shift clocks/jet jag45:10. Exercise: morning people vs evening people47:58. Stronger in the afternoon50:30. Shift work and eating during the night54:30. Best to do rotating or constant routine shift work?55:57. Best time to exercise if shift worker?57:55. Clocks are disrupted in diabetes1:00:00. Researchers need to consider circadian rhythms1:03:42. Is there circadian rhythm cross talk between organs?1:06:03. Inflammation, muscle and circadian rhythms1:08:12. The heart and circadian rhythms1:11:30. Bone-muscle cross talk and circadian rhythms1:13:28. Sex differences and circadian rhythms1:15:00. Applicability of mouse studies to humans1:16:42. Controversies in the field1:17:52. Takeaway messages1:20:12. Outro (9 seconds)Inside Exercise brings to you the who's who of research in exercise metabolism, exercise physiology and exercise’s effects on health. With scientific rigor, these researchers discuss popular exercise topics while providing practical strategies for all.The interviewer, Emeritus Professor Glenn McConell, has an international research profile following 30 years of Exercise Metabolism research experience while at The University of Melbourne, Ball State University, Monash University, the University of Copenhagen and Victoria University.He has published over 120 peer reviewed journal articles and recently edited an Exercise Metabolism eBook written by world experts on 17 different topics (https://link.springer.com/book/10.1007/978-3-030-94305-9).Connect with Inside Exercise and Glenn McConell at:Twitter: @Inside_exercise and @GlennMcConell1Instagram: insideexerciseFacebook: Glenn McConellLinkedIn: Glenn McConell https://www.linkedin.com/in/glenn-mcconell-83475460ResearchGate: Glenn McConellEmail: [email protected] to Inside exercise:Spotify: shorturl.at/tyGHLApple Podcasts: shorturl.at/oFQRUYouTube: https://www.youtube.com/@insideexerciseAnchor: https://anchor.fm/insideexerciseGoogle Podcasts: shorturl.at/bfhHIAnchor: https://anchor.fm/insideexercisePodcast Addict: https://podcastaddict.com/podcast/4025218Not medical advice