EPISODE · Mar 24, 2026 · 48 MIN
Alzheimer’s Starts Decades Before Symptoms
from The Early Perspective · host Avanish Srinivasan
What if Alzheimer’s disease begins decades before symptoms and you wouldn’t even know?In this episode, I’m joined by Dr. Adam Brickman, Professor of Neuropsychology at Columbia University, to break down how the brain actually ages and what’s really happening in Alzheimer’s disease.We explore the difference between normal cognitive aging and neurodegeneration, why dementia and Alzheimer’s are not the same, and how biological changes like amyloid plaques can exist long before symptoms appear.Dr. Brickman also explains why removing these plaques doesn’t necessarily cure the disease, and how factors like vascular health, lifestyle, and socioeconomic conditions shape cognitive decline.This episode offers a clearer, more accurate understanding of brain aging and what it means for prevention, treatment, and the future of neuroscience.Hosted by Avanish Srinivasan.Learn more at youngaxons.com.
What this episode covers
What if Alzheimer’s disease begins decades before symptoms and you wouldn’t even know?In this episode, I’m joined by Dr. Adam Brickman, Professor of Neuropsychology at Columbia University, to break down how the brain actually ages and what’s really happening in Alzheimer’s disease.We explore the difference between normal cognitive aging and neurodegeneration, why dementia and Alzheimer’s are not the same, and how biological changes like amyloid plaques can exist long before symptoms appear.Dr. Brickman also explains why removing these plaques doesn’t necessarily cure the disease, and how factors like vascular health, lifestyle, and socioeconomic conditions shape cognitive decline.This episode offers a clearer, more accurate understanding of brain aging and what it means for prevention, treatment, and the future of neuroscience.Hosted by Avanish Srinivasan.Learn more at youngaxons.com.
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Alzheimer’s Starts Decades Before Symptoms
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