CAR-T in Solid Tumors: A Cancer Progress Sneak Peek

Professor Gregg Stone explains the results of the FREEDOM COVID Anticoagulation Strategy Randomized Trial. The main conclusions are among non-critically ill pts hospitalized with COVID-19, at 30 days the lower incidence of the primary outcome for therapeutic dose compared with prophylactic dose did not reach statistical significance. However, significantly fewer pts treated with therapeutic-dose died or required endotracheal intubation within 30 days. Outcomes with therapeutic-dose enoxaparin and apixaban were similar, and bleeding was infrequent with all three regimens. Based on these findings, the use of therapeutic-dose anticoagulation may improve outcomes in non-critically ill patients hospitalized with COVID-19 who are at increased risk for adverse events but do not yet require ICU level-of care. Video: https://medicaldigest.org/scientific-contents/interview:freedom-covid-anticoagulation-strategy-randomized-trial

Ann Ramsey is a lifelong horsewoman. She graduated from California Polytechnic State University in San Luis Obispo in 2006, with a bachelor's degree in Animal Science with a concentration in Equine Science. Currently, Ramsey focuses therapeutic farriery and equine rehabilitation. She is an AAPF-accredited farrier and focuses on therapeutic shoeing with modern materials, tools and computer software. Additionally, Ramsey holds a certification in Equine Rehabilitation from the Animal Rehab Institute in Florida. She works with veterinarians creating therapeutic exercise protocols for horses, helping them return to work after injury. Given her dual perspectives she is relied upon for educational seminars, clinics and online classes.

Drug repurposing (DR) (also known as drug repositioning) is a process of identifying new therapeutic use(s) for old/existing/available drugs. It is an effective strategy in discovering or developing drug molecules with new pharmacological/therapeutic indications. In recent years, many pharmaceutical companies are developing new drugs with the discovery of novel biological targets by applying the drug repositioning strategy in drug discovery and development programs. Thus, drug repositioning is an effective alternative approach to the traditional drug discovery process.

On this week’s episode of the Psyched to Practice Podcast we hope to have you saying “yes, and…” as we talk improv. Ray and Paul have the pleasure of talking to Dr. Michael Alcée about his new book Therapeutic Improvisation: How to Stop Winging It and Own It as a Therapist. Listen in as we connect the art and science of therapy in this Practice in Action episode, Therapeutic Improv.