Cerebrospinal fluid B-cell expansion

A first episode of central nervous system (CNS) demyelination may represent heterogeneous entities such as acute disseminated encephalomyelitis, clinically isolated syndrome, neuromyelitis optica (NMO), or multiple sclerosis. As new immune therapies become available, it is increasingly important to make an early diagnosis. In this podcast, Editor in Chief of Developmental Medicine & Child Neurology, Dr Peter Baxter, talks to Professor Russell Dale (Clinical School, The Children’s Hospital at Westmead, Sydney) about the paper he co-authored in the September issue of the journal: 'Cerebrospinal fluid B-cell expansion in longitudinally extensive transverse myelitis associated with neuromyelitis optica immunoglobulin G' by Russell C Dale, Esther Tantsis, Vera Merheb, Fabienne Brilot. Read the paper:http://onlinelibrary.wiley.com/doi/10.1111/j.1469-8749.2011.03975.x/abstract