EPISODE · Dec 15, 2025 · 33 MIN
Environmental impacts on health, and the future of AI in medicine | Chirag Patel
from Metascience Matters · host Randy Ellis
Chirag Patel is an Associate Professor of Biomedical Informatics at Harvard Medical School, renowned for his expertise in using computational methods to understand human health and disease from high-throughput data streams. He specializes in understanding the role in the intersection of genetics and environmental exposures (the exposome) in human health, as well as various disease areas such as diabetes, cardiovascular disease, and Alzheimer’s disease.CONTACT RANDY:Feedback: [email protected] LINKS:Chirag’s Lab: https://www.chiragjpgroup.org/TEDx talk on the exposome: • Exposome: decoding human health and diseas... OUTLINE:0:00 - Introduction0:37 - How do you decide what to work on?1:57 - Where does metascience fit into your work?3:57 - Vibration-of-effects analysis6:41 - How does VoE change how we see existing scientific work?9:22 - The biggest challenges in the replication crisis within biomedical informatics11:48 - Environment-wide association study of Type 2 diabetes15:04 - The exposome17:30 - Policy vs. precision medicine applications of the exposome20:09 - The patient exposome22:38 - HBA1C for diabetes as a bridge to the exposome23:54 - Broader metascientific issues of the exposome25:01 - The effects of extreme weather events on human health29:35 - AI for biomedical informatics, the exposome, metascience31:19 - Advice for listeners interested in pursuing research like Chirag’s 32:53 - Outro
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Environmental impacts on health, and the future of AI in medicine | Chirag Patel
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