Closing the Postoperative Gap: GammaTile and the Future of CNS Brachytherapy

In this episode of Brachy Bites, Dr. Agarwal interviews Dr. Michael Garcia who breaks down the clinical problem that GammaTile was designed to solve: the vulnerability of the postoperative treatment gap in brain tumor care. From the limitations of standard postoperative SRS to the biology of rapid early recurrence, we explore how immediate, surgically targeted cesium-131 brachytherapy is reshaping local control in brain metastases and glioblastoma. Dr. Garcia discusses patient selection, preoperative planning, workflow, and barriers to adoption. We also unpack the ROADS interim data demonstrating a reduction in recurrence or death versus postoperative SRS. If confirmed, could this redefine standard of care for operable brain metastases? This conversation explores the evidence, the biology, and what comes next for CNS brachytherapy.