Cognitive Decline and Glycation episode artwork

EPISODE · May 30, 2025 · 17 MIN

Cognitive Decline and Glycation

from The College of Glycation with Dr. Paul Reynolds · host Paul Reynolds

What if the foods we eat are quietly sabotaging our brain health? In this episode of The College of Glycation, Professor Paul Reynolds takes us deep into the science of glycation and its overlooked role in cognitive decline. From Alzheimer’s and Parkinson’s to anxiety and depression, we explore how sugar-damaged proteins—known as AGEs—wreak havoc on the brain’s delicate chemistry.You’ll hear the latest research on how high-AGE diets, insulin resistance, and inflammation converge to accelerate aging in the brain, and why conventional medications may not be enough. But it’s not all bad news—there’s promising evidence that dietary changes, including ketogenic approaches, may offer a way forward.If you’re curious about the hidden links between metabolism and mental health, this episode connects the dots with clarity and depth—no hype, just real science and actionable insights.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products) 

What if the foods we eat are quietly sabotaging our brain health? In this episode of The College of Glycation, Professor Paul Reynolds takes us deep into the science of glycation and its overlooked role in cognitive decline. From Alzheimer’s and Parkinson’s to anxiety and depression, we explore how sugar-damaged proteins—known as AGEs—wreak havoc on the brain’s delicate chemistry.You’ll hear the latest research on how high-AGE diets, insulin resistance, and inflammation converge to accelerate aging in the brain, and why conventional medications may not be enough. But it’s not all bad news—there’s promising evidence that dietary changes, including ketogenic approaches, may offer a way forward.If you’re curious about the hidden links between metabolism and mental health, this episode connects the dots with clarity and depth—no hype, just real science and actionable insights.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)

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Cognitive Decline and Glycation

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This episode was published on May 30, 2025.

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What if the foods we eat are quietly sabotaging our brain health? In this episode of The College of Glycation, Professor Paul Reynolds takes us deep into the science of glycation and its overlooked role in cognitive decline. From Alzheimer’s and...

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