EPISODE · Feb 14, 2026 · 22 MIN
Episode 2: Acute Kidney Injury — From Diagnosis to Dialysis Decision
from NephBytes · host Dr Amit Kaushal
A 72-year-old woman in the ICU with pneumonia. Creatinine doubling overnight. Urine output dropping. The intern asks: "Should we start dialysis?"In this episode, we walk through the complete approach to acute kidney injury — KDIGO staging, the diagnostic workup (post-renal, pre-renal, intrinsic), the critical role of FENa and urine sediment, volume and medication management, and the evidence behind dialysis timing including the landmark STARRT-AKI trial.By the end, you'll know exactly when to pull the trigger on dialysis — and when watchful waiting is the smarter move.Based on core concepts from Comprehensive Clinical Nephrology (Feehally, Floege, Tonelli & Johnson), with original clinical commentary and board-style takeaways.
What this episode covers
A 72-year-old woman in the ICU with pneumonia. Creatinine doubling overnight. Urine output dropping. The intern asks: "Should we start dialysis?"In this episode, we walk through the complete approach to acute kidney injury — KDIGO staging, the diagnostic workup (post-renal, pre-renal, intrinsic), the critical role of FENa and urine sediment, volume and medication management, and the evidence behind dialysis timing including the landmark STARRT-AKI trial.By the end, you'll know exactly when to pull the trigger on dialysis — and when watchful waiting is the smarter move.Based on core concepts from Comprehensive Clinical Nephrology (Feehally, Floege, Tonelli & Johnson), with original clinical commentary and board-style takeaways.
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Episode 2: Acute Kidney Injury — From Diagnosis to Dialysis Decision
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