EPISODE · Aug 15, 2025 · 22 MIN
Episode 5: Tesamorelin vs. Ipamorelin | Peptides for Growth Hormone, Fat Loss, and Better Sleep
from Peptides for Women · host Jennifer Woodward
Welcome back to Peptides for Women podcast, my little 80s babes! Today we’re digging into two of the most fascinating (and fun to say!) peptides: Tesamorelin and Ipamorelin.Both of these peptides help your body make more growth hormone, which naturally declines in your 30s, 40s, and 50s. And since growth hormone is the secret sauce for lean muscle, fat loss, skin, sleep, and recovery, this is a conversation you don’t want to miss.In this episode, I break down:Why tesamorelin is especially powerful for midlife belly fat and body compositionThe “thermostat vs. tap” analogy to help you understand their unique rolesHow ipamorelin supports deep sleep, recovery, and mood—without messing with other hormonesWhat the research really says about fat loss, muscle, and brain healthHow these peptides can be used together for even better resultsThe importance of healthy foundations (protein, lifting, sleep, sun, steps) before adding peptides📘 Resources Mentioned:1. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trialhttps://pubmed.ncbi.nlm.nih.gov/25038357/2. Effects of Tesamorelin on Neurocognitive Impairment in Persons With HIV and Abdominal Obesityhttps://pubmed.ncbi.nlm.nih.gov/39813152/3. Tesamorelin Modestly Reduces Liver Fathttps://www.jwatch.org/na35376/2014/08/08/tesamorelin-modestly-reduces-liver-fat4. Ipamorelin, the first selective growth hormone secretagoguehttps://pubmed.ncbi.nlm.nih.gov/9849822/5. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female ratshttps://pubmed.ncbi.nlm.nih.gov/10828840/6. The role of peptides in bone healing and regeneration: a systematic reviewhttps://pmc.ncbi.nlm.nih.gov/articles/PMC4940902/Links & Resources:🔗 Learn more at: elliemd.com/JenniferWoodwardNutrition🎯 Take my free peptide quiz and get a personalized, midlife-smart roadmap for the peptides that actually match your symptoms and goals: https://quiz.jenniferwoodwardnutrition.com/peptide-quiz🎓 Enroll in the Peptides for Practitioners Certification Course and get $100 off for podcast subscribers: https://www.carrotsncake.com/offers/TrVo7mCz?coupon_code=PFPJENNIFER🧬 Want to pair GLP-1s with functional lab testing? https://learn.jenniferwoodwardnutrition.com/invitation📩 Grab The Body Edit Guide here for full protocols, labs, and more: https://stan.store/jenniferwoodwardnutrition/p/get-the-body-edit‼️Disclaimer‼️This podcast is for informational purposes only and does not provide medical advice. Always speak with your licensed healthcare provider before starting or changing any medication or treatment plan.
What this episode covers
Welcome back to Peptides for Women podcast, my little 80s babes! Today we’re digging into two of the most fascinating (and fun to say!) peptides: Tesamorelin and Ipamorelin.Both of these peptides help your body make more growth hormone, which naturally declines in your 30s, 40s, and 50s. And since growth hormone is the secret sauce for lean muscle, fat loss, skin, sleep, and recovery, this is a conversation you don’t want to miss.In this episode, I break down:Why tesamorelin is especially powerful for midlife belly fat and body compositionThe “thermostat vs. tap” analogy to help you understand their unique rolesHow ipamorelin supports deep sleep, recovery, and mood—without messing with other hormonesWhat the research really says about fat loss, muscle, and brain healthHow these peptides can be used together for even better resultsThe importance of healthy foundations (protein, lifting, sleep, sun, steps) before adding peptides📘 Resources Mentioned:1. Effect of tesamorelin on visceral fat and liver fat in HIV-infected patients with abdominal fat accumulation: a randomized clinical trialhttps://pubmed.ncbi.nlm.nih.gov/25038357/2. Effects of Tesamorelin on Neurocognitive Impairment in Persons With HIV and Abdominal Obesityhttps://pubmed.ncbi.nlm.nih.gov/39813152/3. Tesamorelin Modestly Reduces Liver Fathttps://www.jwatch.org/na35376/2014/08/08/tesamorelin-modestly-reduces-liver-fat4. Ipamorelin, the first selective growth hormone secretagoguehttps://pubmed.ncbi.nlm.nih.gov/9849822/5. The GH secretagogues ipamorelin and GH-releasing peptide-6 increase bone mineral content in adult female ratshttps://pubmed.ncbi.nlm.nih.gov/10828840/6. The role of peptides in bone healing and regeneration: a systematic reviewhttps://pmc.ncbi.nlm.nih.gov/articles/PMC4940902/Links & Resources:🔗 Learn more at: elliemd.com/JenniferWoodwardNutrition🎯 Take my free peptide quiz and get a personalized, midlife-smart roadmap for the peptides that actually match your symptoms and goals: https://quiz.jenniferwoodwardnutrition.com/peptide-quiz🎓 Enroll in the Peptides for Practitioners Certification Course and get $100 off for podcast subscribers: https://www.carrotsncake.com/offers/TrVo7mCz?coupon_code=PFPJENNIFER🧬 Want to pair GLP-1s with functional lab testing? https://learn.jenniferwoodwardnutrition.com/invitation📩 Grab The Body Edit Guide here for full protocols, labs, and more: https://stan.store/jenniferwoodwardnutrition/p/get-the-body-edit‼️Disclaimer‼️This podcast is for informational purposes only and does not provide medical advice. Always speak with your licensed healthcare provider before starting or changing any medication or treatment plan.
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Episode 5: Tesamorelin vs. Ipamorelin | Peptides for Growth Hormone, Fat Loss, and Better Sleep
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