From “Broken Postdoc” to Professor and RNA Researcher episode artwork

EPISODE · May 28, 2026 · 52 MIN

From “Broken Postdoc” to Professor and RNA Researcher

from The Next Step: Career and Grad School Advice from Our Alumni · host University of Rochester School of Medicine & Dentistry

John Lueck, PhD, associate professor of Pharmacology & Physiology, shares the winding path that led him from graduate school uncertainty and career setbacks to leading cutting-edge research in RNA therapeutics and genetic disease.Lueck reflects on nearly leaving academia after a difficult postdoctoral experience, applying to countless industry jobs, and ultimately finding new momentum through mentorship, collaboration, and translational science. Along the way, he discusses the realities of academic careers, persistence in research, and the importance of building supportive scientific communities.Joining the conversation as faculty co-host is Charles Thornton, MD, professor of Neurology, who brings additional perspective on physician-scientist training, translational research, and developing therapies for genetic disease.Lueck Lab: https://www.urmc.rochester.edu/labs/lueckPharm/Phys PhD program: https://www.urmc.rochester.edu/education/graduate/phd/pharmacology-and-physiologyCharles Thornton: https://www.urmc.rochester.edu/people/112358557-charles-a-thornton

John Lueck, PhD, associate professor of Pharmacology & Physiology, shares the winding path that led him from graduate school uncertainty and career setbacks to leading cutting-edge research in RNA therapeutics and genetic disease.Lueck reflects on nearly leaving academia after a difficult postdoctoral experience, applying to countless industry jobs, and ultimately finding new momentum through mentorship, collaboration, and translational science. Along the way, he discusses the realities of academic careers, persistence in research, and the importance of building supportive scientific communities.Joining the conversation as faculty co-host is Charles Thornton, MD, professor of Neurology, who brings additional perspective on physician-scientist training, translational research, and developing therapies for genetic disease.Lueck Lab: https://www.urmc.rochester.edu/labs/lueckPharm/Phys PhD program: https://www.urmc.rochester.edu/education/graduate/phd/pharmacology-and-physiologyCharles Thornton: https://www.urmc.rochester.edu/people/112358557-charles-a-thornton

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From “Broken Postdoc” to Professor and RNA Researcher

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This episode was published on May 28, 2026.

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John Lueck, PhD, associate professor of Pharmacology & Physiology, shares the winding path that led him from graduate school uncertainty and career setbacks to leading cutting-edge research in RNA therapeutics and genetic disease.Lueck reflects on...

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