Glycation and Bone Health: Osteoporosis and Beyond episode artwork

EPISODE · Jul 16, 2025 · 21 MIN

Glycation and Bone Health: Osteoporosis and Beyond

from The College of Glycation with Dr. Paul Reynolds · host Paul Reynolds

In this episode of The College of Glycation, Dr. Paul Reynolds explores the hidden impact of glycation on bone health—revealing how sugar-driven molecular damage weakens the very foundation of our bodies. Building on previous episodes, Dr. Reynolds explains how advanced glycation end products (AGEs) stiffen collagen, disrupt bone remodeling, and accelerate the progression of osteoporosis and osteoarthritis. Aging and insulin resistance further amplify this damage, making bones more fragile and susceptible to fractures—even when density appears normal.Drawing from cutting-edge research and real clinical insight, Dr. Reynolds breaks down the science behind progressive matrix loss, bone cell dysfunction, and the metabolic factors that erode skeletal strength over time. This episode isn’t just informative—it’s empowering. You’ll come away with practical, evidence-based strategies to lower AGE formation, improve insulin sensitivity, and preserve bone integrity for the long haul.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products) 

In this episode of The College of Glycation, Dr. Paul Reynolds explores the hidden impact of glycation on bone health—revealing how sugar-driven molecular damage weakens the very foundation of our bodies. Building on previous episodes, Dr. Reynolds explains how advanced glycation end products (AGEs) stiffen collagen, disrupt bone remodeling, and accelerate the progression of osteoporosis and osteoarthritis. Aging and insulin resistance further amplify this damage, making bones more fragile and susceptible to fractures—even when density appears normal.Drawing from cutting-edge research and real clinical insight, Dr. Reynolds breaks down the science behind progressive matrix loss, bone cell dysfunction, and the metabolic factors that erode skeletal strength over time. This episode isn’t just informative—it’s empowering. You’ll come away with practical, evidence-based strategies to lower AGE formation, improve insulin sensitivity, and preserve bone integrity for the long haul.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)

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Glycation and Bone Health: Osteoporosis and Beyond

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This episode was published on July 16, 2025.

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In this episode of The College of Glycation, Dr. Paul Reynolds explores the hidden impact of glycation on bone health—revealing how sugar-driven molecular damage weakens the very foundation of our bodies. Building on previous episodes, Dr. Reynolds...

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