EPISODE · Nov 5, 2025 · 16 MIN
Glycation and Exercise
from The College of Glycation with Dr. Paul Reynolds · host Paul Reynolds
In this episode of the College of Glycation, Dr. Paul Reynolds—Professor of Cell Biology and Physiology—reveals how glycation quietly undermines muscle strength, recovery, and performance. By binding sugars to proteins in the body, glycation produces toxic compounds known as AGEs that stiffen muscle fibers, disrupt collagen, and trigger chronic inflammation. The result? Slower recovery, greater injury risk, and accelerated muscle aging—even in those who train regularly.Dr. Reynolds connects cutting-edge biochemistry with everyday fitness, showing how high-sugar diets, poor recovery habits, and metabolic stress blunt the benefits of exercise. Backed by peer-reviewed research, he explores how glycation impairs flexibility, vascular health, and muscle regeneration—and shares practical strategies to reverse the damage. From anti-glycation nutrients like carnosine to smarter training and nutrition choices, this episode offers evidence-based tools to protect your muscles, optimize performance, and extend your athletic longevity.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3 Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount. Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20) Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)
What this episode covers
In this episode of the College of Glycation, Dr. Paul Reynolds—Professor of Cell Biology and Physiology—reveals how glycation quietly undermines muscle strength, recovery, and performance. By binding sugars to proteins in the body, glycation produces toxic compounds known as AGEs that stiffen muscle fibers, disrupt collagen, and trigger chronic inflammation. The result? Slower recovery, greater injury risk, and accelerated muscle aging—even in those who train regularly.Dr. Reynolds connects cutting-edge biochemistry with everyday fitness, showing how high-sugar diets, poor recovery habits, and metabolic stress blunt the benefits of exercise. Backed by peer-reviewed research, he explores how glycation impairs flexibility, vascular health, and muscle regeneration—and shares practical strategies to reverse the damage. From anti-glycation nutrients like carnosine to smarter training and nutrition choices, this episode offers evidence-based tools to protect your muscles, optimize performance, and extend your athletic longevity.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3 Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount. Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20) Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)
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Glycation and Exercise
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