Glycation and Metabolic Syndrome episode artwork

EPISODE · Aug 13, 2025 · 14 MIN

Glycation and Metabolic Syndrome

from The College of Glycation with Dr. Paul Reynolds · host Paul Reynolds

In this episode of the College of Glycation podcast, Dr. Paul Reynolds—Professor of Cell Biology and Biomedical Scientist—uncovers how a single biochemical process, glycation, can set off a chain reaction leading to metabolic syndrome. From stiffened arteries and distorted cholesterol to insulin resistance and mitochondrial damage, advanced glycation end-products (AGEs) quietly but powerfully drive the cluster of conditions that raise the risk of heart disease, stroke, and type 2 diabetes.Drawing on decades of research, Dr. Reynolds explains how AGEs form both inside the body and on our plates, thanks to high-heat cooking, processed foods, and sugar-heavy diets. You’ll learn how these “molecular wrecking balls” fuel inflammation, oxidative stress, and hormonal imbalance—and more importantly, how to interrupt the cycle. Packed with practical tips, this episode empowers you to make small, science-backed changes in your diet, lifestyle, and cooking habits to protect your metabolic health and longevity.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products) 

In this episode of the College of Glycation podcast, Dr. Paul Reynolds—Professor of Cell Biology and Biomedical Scientist—uncovers how a single biochemical process, glycation, can set off a chain reaction leading to metabolic syndrome. From stiffened arteries and distorted cholesterol to insulin resistance and mitochondrial damage, advanced glycation end-products (AGEs) quietly but powerfully drive the cluster of conditions that raise the risk of heart disease, stroke, and type 2 diabetes.Drawing on decades of research, Dr. Reynolds explains how AGEs form both inside the body and on our plates, thanks to high-heat cooking, processed foods, and sugar-heavy diets. You’ll learn how these “molecular wrecking balls” fuel inflammation, oxidative stress, and hormonal imbalance—and more importantly, how to interrupt the cycle. Packed with practical tips, this episode empowers you to make small, science-backed changes in your diet, lifestyle, and cooking habits to protect your metabolic health and longevity.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)

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Glycation and Metabolic Syndrome

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This episode was published on August 13, 2025.

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In this episode of the College of Glycation podcast, Dr. Paul Reynolds—Professor of Cell Biology and Biomedical Scientist—uncovers how a single biochemical process, glycation, can set off a chain reaction leading to metabolic syndrome. From...

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