Glycation and Muscles

In this insightful episode of The College of Glycation, Dr. Paul Reynolds unpacks how sugar-driven molecular reactions silently erode your strength from the inside out. Glycation—the formation of advanced glycation end products (AGEs)—crosslinks muscle proteins, stiffens connective tissue, and disrupts insulin signaling, accelerating the loss of muscle mass and power known as sarcopenia.Drawing from current metabolic and clinical research, Dr. Reynolds explains how AGEs impair muscle regeneration, blunt key growth pathways like Akt/mTOR, and fuel inflammation that blocks repair. But it’s not all decline—he outlines practical, science-based strategies to restore resilience through resistance training, nutrient timing, and antioxidant support. Whether you’re aging, active, or simply determined to stay strong, this episode reveals how managing glycation can help preserve your mobility, vitality, and metabolic health for life.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)