Glycation and Skin Aging

In this episode of The College of Glycation, Dr. Paul Reynolds—Professor of Cell Biology and Physiology—dives into how sugar-driven molecular damage accelerates skin aging from the inside out. Through the lens of glycation, he explains how advanced glycation end products (AGEs) stiffen collagen and elastin, weaken skin structure, and ignite inflammation through the RAGE pathway. The result? Wrinkles, sagging, and a loss of that youthful bounce—driven not just by time, but by diet, UV exposure, and everyday lifestyle choices.Blending cutting-edge research with practical takeaways, Dr. Reynolds reveals how diet, antioxidants, and AGE-lowering strategies can protect your skin’s integrity and slow the clock on aging. Whether you’re into skincare, nutrition, or metabolic health, this episode illuminates the powerful connection between what’s on your plate and what shows in the mirror—and offers science-backed tools to help your skin stay resilient, radiant, and strong.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)