Glycation and Your Mouth as a Metabolic Canary episode artwork

EPISODE · Apr 29, 2026 · 25 MIN

Glycation and Your Mouth as a Metabolic Canary

from The College of Glycation with Dr. Paul Reynolds · host Paul Reynolds

Your gums may be telling you something critical about your metabolic health. In this episode of the College of Glycation, Dr. Paul Reynolds explores the overlooked connection between gum disease, glycation, and systemic inflammation. He explains how Advanced Glycation End Products (AGEs) form and accumulate—and how periodontal disease doesn’t just result from metabolic dysfunction, but can actively drive it. From inflammatory signaling to insulin resistance, this episode reveals how the mouth plays a central role in whole-body health. If you’re interested in metabolism, aging, or the deeper biochemical drivers of chronic disease, this episode offers a powerful new perspective on why oral health is far more than cosmetic—it’s metabolic.Paul’s favorite yerba mate: https://unicity.link/121f260bfe  Yerbe mate with a special formulated Balance fiber: https://ufeelgreat.com/c/PaulReynolds  For the full Metabolic System storefront: https://shop.unicity.com/paulreynolds  Paul’s favorite source for clean, earth-sourced essentials such as salt, electrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb  Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products) 

Your gums may be telling you something critical about your metabolic health. In this episode of the College of Glycation, Dr. Paul Reynolds explores the overlooked connection between gum disease, glycation, and systemic inflammation. He explains how Advanced Glycation End Products (AGEs) form and accumulate—and how periodontal disease doesn’t just result from metabolic dysfunction, but can actively drive it. From inflammatory signaling to insulin resistance, this episode reveals how the mouth plays a central role in whole-body health. If you’re interested in metabolism, aging, or the deeper biochemical drivers of chronic disease, this episode offers a powerful new perspective on why oral health is far more than cosmetic—it’s metabolic.Paul’s favorite yerba mate: https://unicity.link/121f260bfe  Yerbe mate with a special formulated Balance fiber: https://ufeelgreat.com/c/PaulReynolds  For the full Metabolic System storefront: https://shop.unicity.com/paulreynolds  Paul’s favorite source for clean, earth-sourced essentials such as salt, electrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb  Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)

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Glycation and Your Mouth as a Metabolic Canary

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This episode is 25 minutes long.

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This episode was published on April 29, 2026.

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Your gums may be telling you something critical about your metabolic health. In this episode of the College of Glycation, Dr. Paul Reynolds explores the overlooked connection between gum disease, glycation, and systemic inflammation. He explains how...

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