Glycation, Mitochondria, and Energy Metabolism

In this eye-opening episode of the College of Glycation, Dr. Paul Reynolds—Professor of Cell Biology and Physiology—unpacks the hidden connection between glycation, mitochondrial damage, and declining cellular energy. He explains how sugar-driven advanced glycation end products (AGEs) sabotage the mitochondria—the body’s energy factories—by damaging key proteins, increasing oxidative stress, and choking off ATP production. The result? Fatigue, brain fog, metabolic inflexibility, and accelerated aging.Blending cutting-edge research with practical strategies, Dr. Reynolds reveals how to protect and restore your mitochondria through blood sugar control, targeted nutrition, and exercise that sparks mitochondrial renewal. Whether you’re aiming for sharper thinking, higher energy, or healthier aging, this episode offers the science and solutions to keep your cellular engines running strong.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)