HHS & NIH Evidence Review on Pediatric Gender Dysphoria — Expert Panel Discussion episode artwork

EPISODE · Dec 16, 2025 · 1H 47M

HHS & NIH Evidence Review on Pediatric Gender Dysphoria — Expert Panel Discussion

from The Director's Desk · host National Institutes of Health

In this episode of The Director’s Desk, NIH Director Dr. Jay Bhattacharya hosts a roundtable with the primary authors of the new HHS peer-reviewed report, “Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices.”This comprehensive federal review evaluates the scientific evidence behind current pediatric gender dysphoria treatments—including puberty blockers, cross-sex hormones, and surgical interventions—and concludes that these approaches carry significant and long-term risks for children and adolescents.Featured Authors & Contributors:• Evgenia Abbruzzese – Society for Evidence-Based Gender Medicine• Alex Byre, PhD – Massachusetts Institute of Technology• Farr Curlin, MD – Duke University• Moti Gorin, PhD, MBE – Colorado State University• Kristopher Kaliebe, MD, DFAACAP – University of South Florida• Michael K. Laidlaw, MD – Michael K. Laidlaw MD, Inc.• Kathleen McDeavitt, MD – Baylor College of Medicine• Leor Sapir, PhD – Manhattan Institute for Policy Research• Yuan Zhang, PhD – Evidence Bridge• Additional contributors to the HHS evidence review and peer-review processTogether, they discuss the report’s major findings, the strength and limitations of the existing evidence base, long-term clinical outcomes, and the implications for research, clinical practice, and public health policy.To learn more or read the full HHS report, visit HHS.gov.

In this episode of The Director’s Desk, NIH Director Dr. Jay Bhattacharya hosts a roundtable with the primary authors of the new HHS peer-reviewed report, “Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices.”This comprehensive federal review evaluates the scientific evidence behind current pediatric gender dysphoria treatments—including puberty blockers, cross-sex hormones, and surgical interventions—and concludes that these approaches carry significant and long-term risks for children and adolescents.Featured Authors & Contributors:• Evgenia Abbruzzese – Society for Evidence-Based Gender Medicine• Alex Byre, PhD – Massachusetts Institute of Technology• Farr Curlin, MD – Duke University• Moti Gorin, PhD, MBE – Colorado State University• Kristopher Kaliebe, MD, DFAACAP – University of South Florida• Michael K. Laidlaw, MD – Michael K. Laidlaw MD, Inc.• Kathleen McDeavitt, MD – Baylor College of Medicine• Leor Sapir, PhD – Manhattan Institute for Policy Research• Yuan Zhang, PhD – Evidence Bridge• Additional contributors to the HHS evidence review and peer-review processTogether, they discuss the report’s major findings, the strength and limitations of the existing evidence base, long-term clinical outcomes, and the implications for research, clinical practice, and public health policy.To learn more or read the full HHS report, visit HHS.gov.

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HHS & NIH Evidence Review on Pediatric Gender Dysphoria — Expert Panel Discussion

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In this episode of The Director’s Desk, NIH Director Dr. Jay Bhattacharya hosts a roundtable with the primary authors of the new HHS peer-reviewed report, “Treatment for Pediatric Gender Dysphoria: Review of Evidence and Best Practices.”This...

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