EPISODE · Jun 16, 2026 · 11 MIN
How Biotech Startups Use Circular RNA for Stable Therapies
from Biotech Business with Fexingo: Life Sciences Startups, Drug Discovery, and FDA Approvals · host Fexingo
Episode 55 of Biotech Business with Fexingo dives into circular RNA, the cutting-edge molecule that biotech startups are engineering for more stable, longer-lasting therapies. Lucas explains why circular RNA resists degradation better than linear mRNA, and Luna highlights a specific startup—Orna Therapeutics—that raised $221 million to develop circular RNA-based immunotherapies. They discuss how the circular structure avoids the immune detection that plagued early mRNA, the potential for one-shot treatments, and the manufacturing challenges that remain. If you want to understand the next wave of RNA medicine beyond vaccines, this episode gives you the concrete science and business angle. #CircularRNA #RNATherapeutics #BiotechStartups #OrnaTherapeutics #DrugDiscovery #mRNA #Immunotherapy #Biotechnology #LifeSciences #GeneTherapy #RNAStability #BiotechFunding #Business #Technology #FexingoBusiness #BusinessPodcast #HealthcareInnovation #StartupFunding Keep every episode free: buymeacoffee.com/fexingo
What this episode covers
Episode 55 of Biotech Business with Fexingo dives into circular RNA, the cutting-edge molecule that biotech startups are engineering for more stable, longer-lasting therapies. Lucas explains why circular RNA resists degradation better than linear mRNA, and Luna highlights a specific startup—Orna Therapeutics—that raised $221 million to develop circular RNA-based immunotherapies. They discuss how the circular structure avoids the immune detection that plagued early mRNA, the potential for one-shot treatments, and the manufacturing challenges that remain. If you want to understand the next wave of RNA medicine beyond vaccines, this episode gives you the concrete science and business angle. #CircularRNA #RNATherapeutics #BiotechStartups #OrnaTherapeutics #DrugDiscovery #mRNA #Immunotherapy #Biotechnology #LifeSciences #GeneTherapy #RNAStability #BiotechFunding #Business #Technology #FexingoBusiness #BusinessPodcast #HealthcareInnovation #StartupFunding Keep every episode free: buymeacoffee.com/fexingo
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How Biotech Startups Use Circular RNA for Stable Therapies
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