How Reversible is Glycation?

In this episode of the College of Glycation, Dr. Paul Reynolds explores one of the most important questions in metabolic health: Is glycation reversible? While some damage—especially in long-lived tissues like collagen—can persist for decades, this episode reveals that the body is far from helpless. Dr. Reynolds breaks down the science of how glycation forms, why certain stages are more reversible than others, and the built-in systems your body uses to defend against and clear this damage.More importantly, he translates that science into practical strategies you can use right away. From improving blood sugar control and reducing dietary AGEs to leveraging fasting, exercise, and targeted supplementation, this episode reframes the goal—not as fully reversing damage, but as slowing its accumulation and changing your long-term health trajectory.Paul’s favorite yerba mate: https://unicity.link/121f260bfe Yerbe mate with a special formulated Balance fiber: https://ufeelgreat.com/c/PaulReynolds For the full Metabolic System storefront: https://shop.unicity.com/paulreynolds Paul’s favorite source for clean, earth-sourced essentials such as salt, electrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount. Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20) Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)