Kelsey Grammer: A Brother’s Love and Loss

What this episode covers

In 1975 Kelsey Grammer’s 18-year-old sister, Karen, was murdered. For fifty years his loving memories of her were colored by questions about her death. In this moving conversation, Kelsey tells Anderson how he finally found answers and, in doing so, the beloved sister he lost so long ago. This conversation contains some graphic descriptions of violence. Join the community to share your story and watch Anderson's weekly streaming show All There Is Live at cnn.com/allthereis. Host: Anderson Cooper Showrunner: Haley Thomas Producers: Chuck Hadad, Grace Walker, Emily Williams Associate Producer: Kyra Dahring Video Editor: Eric Zembrzuski Technical Director: Dan Dzula Bookers: Kerry Rubin and Kari Pricher Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Frequently Asked Questions

How long is this episode of All There Is with Anderson Cooper?

This episode is 33 minutes long.

When was this All There Is with Anderson Cooper episode published?

This episode was published on December 17, 2025.

What is this episode about?

In 1975 Kelsey Grammer’s 18-year-old sister, Karen, was murdered. For fifty years his loving memories of her were colored by questions about her death. In this moving conversation, Kelsey tells Anderson how he finally found answers and, in doing so,...

Can I download this All There Is with Anderson Cooper episode?

Yes, you can download this episode by clicking the download button on the episode player, or subscribe to the podcast in your preferred podcast app for automatic downloads.