Keto & Carnivore Diets

In this episode of the College of Glycation, Dr. Paul Reynolds examines one of the most debated questions in metabolic health: do ketogenic and carnivore diets worsen glycation—or help prevent it? Breaking down the biochemistry, he explains how glycation forms advanced glycation end products (AGEs) that drive inflammation, oxidative stress, and accelerated aging, and why chronically elevated blood glucose is the primary trigger behind this damage.Dr. Reynolds explores how carbohydrate restriction lowers HbA1c and reduces endogenous AGE formation, while addressing concerns about dietary AGEs from cooked meat and methylglyoxal production during ketosis. He also highlights the protective role of beta-hydroxybutyrate (BHB), the body’s glyoxalase detoxification system, and the often-overlooked impact of fructose in accelerating glycation. The result is a clear, evidence-based look at how ketogenic and carnivore diets intersect with metabolic chemistry—and what that means for long-term health.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3  Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.  Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhb Paul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)  Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)