Navigating Treatment-Resistant Depression (TRD) - New ways to heal your depression episode artwork

EPISODE · Feb 28, 2026 · 19 MIN

Navigating Treatment-Resistant Depression (TRD) - New ways to heal your depression

from The Healing and Life Transformation Podcast with Mark L Lockwood BA(hons)(psy) · host markllockwood

What happens when the first, second, or third antidepressant doesn't work? In this episode, we dive into the science of Treatment-Resistant Depression (TRD). We explore emerging therapies—from Ketamine and TMS to lifestyle interventions—and discuss why a "failed" treatment isn't a failure of the patient.

What happens when the first, second, or third antidepressant doesn't work? In this episode, we dive into the science of Treatment-Resistant Depression (TRD). We explore emerging therapies—from Ketamine and TMS to lifestyle interventions—and discuss why a "failed" treatment isn't a failure of the patient.

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Navigating Treatment-Resistant Depression (TRD) - New ways to heal your depression

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This episode was published on February 28, 2026.

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What happens when the first, second, or third antidepressant doesn't work? In this episode, we dive into the science of Treatment-Resistant Depression (TRD). We explore emerging therapies—from Ketamine and TMS to lifestyle interventions—and discuss...

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