Practical Glycation Busters and Supplements

In this episode of the College of Glycation, Dr. Paul Reynolds—Professor of Cell Biology and Physiology—shifts from explaining the science of glycation to exploring practical strategies for fighting it. Glycation and the buildup of advanced glycation end products (AGEs) contribute to aging, inflammation, and many chronic diseases, but there are evidence-based ways to slow this process. Dr. Reynolds breaks down the research behind several powerful tools that may help reduce glycation damage and improve metabolic health.This episode highlights supplements and dietary strategies that target glycation at multiple stages, including L-carnosine, pyridoxamine, GlyNAC (glycine + NAC), beta-hydroxybutyrate (BHB), and the polyphenols found in yerba mate. Dr. Reynolds also discusses the potential role of allulose as a lower-glycation sugar alternative and explains why improving insulin sensitivity and reducing blood glucose are foundational for protecting long-term cellular health. If you’re interested in slowing the molecular processes that contribute to aging and chronic disease, this episode provides practical, science-backed insights you can start applying today.Paul’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/C63EE3Paul’s favorite source for clean, earth-sourced essentials such as salt, elecrolytes, hydration, pre-workout and more. Go to https://redmond.life and use PAULSALT for 15% discount.Paul’s favorite exogenous ketones: A high-quality option is the NSF-certified goBHB from Clean Form Nutrition, where you can use the code Paul10 for a 10% discount: https://cleanformnutrition.com/products/go-bhbPaul’s favorite allulose source: https://rxsugar.com (discount: PAUL20)Paul’s favorite health check-up for men or women: https://blokes.co/DRPAUL (discount: DRPAUL for 50% off of labs and smart supplements and 15% off all other products)