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In this episode, I explain the biology, symptoms, causes and types of bipolar disorder (sometimes called bipolar depression). I discuss neuroplasticity and how the brain normally regulates mood, energy, and perceptions; then, I contrast that with the biology of bipolar disorder, which is characterized by extremes of energy and mood, e.g., mania and depression. I outline the mechanisms through which bipolar disorder manifests in the brain, including deficits of interoception and reduced connections between the parietal and limbic systems. I also outline how treatment options (such as lithium) work in part through homeostatic plasticity.’ I discuss not only lithium but also the treatment of bipolar with ketamine, different talk therapies, electroconvulsive therapy, transcranial magnetic stimulation, and nutraceuticals, including Omega-3 and Inositol supplementation. This episode should interest anyone who has or knows someone with bipolar disorder and, more broadly, those interested in how the brain works to create a balance between thoughts, energy levels, focus, and mood. For the full show notes, visit hubermanlab.com. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Timestamps (00:00:00) Bipolar Disorder (00:03:42) Tool: Appetite Suppression & GLP-1, Parallel Pathways, Yerba Mate (00:9:19) Sponsors: AG1, LMNT (00:14:24) Prevalence & Severity of Bipolar Disorder (00:16:30) Bipolar Disorder I, Diagnostic Criteria of Mania (00:28:58) Bipolar Disorder II, Individual Variability (00:33:07) Bipolar I vs. Bipolar II: Manic, Depressive & Symptom-Free States (00:38:20) Consequences of Bipolar Disorder, Heritability (00:46:53) Bipolar Disorder vs. Borderline Personality Disorder (00:51:51) Mania & Depression, Negative Impacts (00:53:06) History of Lithium Treatment (01:02:44) Lithium Treatment & Side-Effects (01:05:05) Effects of Lithium: BDNF, Anti-inflammatory & Neuroprotection (01:10:10) Neural Circuits of Bipolar Disorder, Interoception, Hyper- vs. Hypoactivity (01:17:11) Neural States & Mania, Parietal Lobe & Limbic System (01:22:58) Homeostatic Plasticity, Synaptic Scaling, Lithium & Ketamine (01:36:00) Talk Therapies: Cognitive Behavioral Therapy, Family-Focused Therapy, Interpersonal & Social Rhythm Therapy (01:43:18) Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (rTMS) (01:48:01) Psylocibin, Cannabis (01:51:50) Lifestyle Support, Supplements: Inositol & Omega-3 Fatty Acids (02:03:31) Omega-3s, Membrane Fluidity & Neuroplasticity (02:06:44) Mania, Creativity & Occupations (02:15:33) Bipolar Disorder: Diagnosis, Neural Circuits & Treatment (02:17:45) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

In this interview, Michael discusses his work with patients with bipolar disorder, and his own background as an entrepreneur, and how this has lead him into research and treatment of entrepreneurs with bipolar disorder. Michael explains what bipolar disorder is, and how to accurately diagnose Bipolar Disorder I, Bipolar Disorder II, hypomania, and mania and how they are different than Major Depression, ADHD, and/or complex trauma. He discusses the importance of assessing for a genetic history, as bipolar disorder his highly hereditable. He talks about how individuals raised by a bipolar parent may have some of the qualities of bipolar disorder (e.g., creativity, drive, high energy), but not bipolar disorder itself and some of the theories on the benefits of heredity of part of the genetics for bipolar disorder. He explains how important medication is to the treatment of bipolar disorder, and how any treatment should build upon that, rather than focusing on therapy first, then adding medication. Michael discusses the evidence based therapies for bipolar disorder including Interpersonal Therapy (IPT), Cognitive Behavioral Therapy (CBT), Psychoeducation, Family Focus Therapy (FFT), and Social Rhythm Therapy (SRT). He discusses the elements being related to self care (e.g., light therapy, time anchors) and a plan for addressing prodromal signs that an episode is coming, as well as examine the effect bipolar disorder has on relationship with partners and family members in order to strengthen those relationships. He explains that many folks with bipolar disorder go into the fields of art, science, and entrepreneurship, and how the symptoms can be harnessed to aid in success, while simultaneously managing the symptoms to prevent the deleterious effects of the disorder. Michael Freeman, M.D. is a psychiatrist, psychologist, consultant and former CEO who serves on the faculty of the Department of Psychiatry at the University of California, San Francisco School of Medicine. His clinical practice is focused on the treatment of people with mood, anxiety and attention disorders, and his consulting practice is focused on entrepreneurship and performance enhancement coaching. Michael’s research addresses the strengths, vulnerabilities, and mental health issues faced by entrepreneurs. He has held CEO and C-level leadership positions in several public and private sector health care organizations. Michael brings medical, psychological, prevention/self-care and executive competencies to his clinical and consulting practice.

This episode talks about how I navigate through my world while in Quarantine. What were my initial thoughts how did I deal with a psychotic break. It was interesting making this episode because I have come so far with all the work I have done as a Black woman with Bipolar. I am taking steps everyday to overcome the obstacles. Sharing is caring! So Like, Subscribe and Share. Resources: https://www.nimh.nih.gov/health/topics/bipolar-disorder/index.shtmlhttps://www.mhanational.org/get-involved/contact-us

In this enlightening podcast, we explored the art of “Elevating Your Black-Owned Business Brand Identity Online.” We emphasized the pivotal role of brand identity, from establishing a captivating visual identity to building a dynamic online presence through website optimization, engaging social media, and content marketing. Cultivating a strong online community and continuously measuring success were […] The post GoBlackly: Elevating Your Black-Owned Business Brand Identity Online | Ep 3 first appeared on GoBlackly: Digital Marketing For Black-Owned Businesses.