EPISODE · Apr 30, 2026 · 25 MIN
Scanxiety: Managing Drug Resistance Fears with ALK+ Patient Jaymie Knox
from Living With Lung Cancer: Ask Me Anything · host Lung Cancer Foundation of America
What goes through your mind in the days before a lung cancer scan? In this honest conversation, host James Hiter talks with ALK+ patient advocate Jaymie Knox about scanxiety, drug resistance, and the mental gymnastics of living with targeted therapy. Now seven years into treatment with alectinib, Jaymie shares why having a Plan B matters, how she keeps cancer from taking over her headspace, and why the language we use, "the medication failed me," not the other way around, makes a real difference for patients. Together, James and Jaymie talk about: Why drug resistance doesn't have to be the end of the road How scanxiety changes over years of treatment Practical ways to cope before, during, and after scans The power of a strong care team and a clear Plan B Hope grounded in real science and real options Whether you're newly diagnosed or a long-term survivor, this episode offers honest encouragement for the road ahead. Guests: Jaymie Knox Voices of Hope Speakers Bureau Member | ALK+ Survivor & Advocate Jaymie was diagnosed with stage 4 ALK-positive lung cancer in December 2018 at age 32 — newly married and ready to start the next chapter of her life. Her first doctor failed to stage her cancer or explain what lay ahead. She fought for better care and never looked back. Now living in Washington, D.C., Jaymie recently fulfilled a lifelong dream of becoming a foster mom to two young children. She is a passionate advocate for mental health awareness in the lung cancer community and lives by a simple philosophy: "Have your moment, then turn the page." James Hiter Endurance Athlete | Voices of Hope Speakers Bureau Member | Survivor James brings curiosity, determination, and hard-won wisdom to conversations about living with lung cancer. Diagnosed in 2017 with a rare multicystic presentation, he’s undergone three lung surgeries and now operates on roughly 55% of his original lung capacity—yet he still runs every single day. His journey through multidisciplinary tumor boards, second opinions, and ongoing surveillance gives him an intimate understanding of what patients and caregivers face. James asks the questions patients actually want answered because he’s wondered them himself. Show Notes - https://lcfamerica.org/wp-content/uploads/2026/04/LCFA-AMA-Scanxiety-Managing-Drug-Resistance-Fears-Notes.pdf Transcript - https://lcfamerica.org/wp-content/uploads/2026/04/LCFA-AMA-Drug-Resistance-Scanxiety-Transcript.pdf Watch the video - https://youtu.be/O6F_OLwjRHM
What this episode covers
What goes through your mind in the days before a lung cancer scan? In this honest conversation, host James Hiter talks with ALK+ patient advocate Jaymie Knox about scanxiety, drug resistance, and the mental gymnastics of living with targeted therapy. Now seven years into treatment with alectinib, Jaymie shares why having a Plan B matters, how she keeps cancer from taking over her headspace, and why the language we use, "the medication failed me," not the other way around, makes a real difference for patients. Together, James and Jaymie talk about: Why drug resistance doesn't have to be the end of the road How scanxiety changes over years of treatment Practical ways to cope before, during, and after scans The power of a strong care team and a clear Plan B Hope grounded in real science and real options Whether you're newly diagnosed or a long-term survivor, this episode offers honest encouragement for the road ahead. Guests: Jaymie KnoxVoices of Hope Speakers Bureau Member | ALK+ Survivor & Advocate Jaymie was diagnosed with stage 4 ALK-positive lung cancer in December 2018 at age 32 — newly married and ready to start the next chapter of her life. Her first doctor failed to stage her cancer or explain what lay ahead. She fought for better care and never looked back. Now living in Washington, D.C., Jaymie recently fulfilled a lifelong dream of becoming a foster mom to two young children. She is a passionate advocate for mental health awareness in the lung cancer community and lives by a simple philosophy: "Have your moment, then turn the page." James HiterEndurance Athlete | Voices of Hope Speakers Bureau Member | Survivor James brings curiosity, determination, and hard-won wisdom to conversations about living with lung cancer. Diagnosed in 2017 with a rare multicystic presentation, he’s undergone three lung surgeries and now operates on roughly 55% of his original lung capacity—yet he still runs every single day. His journey through multidisciplinary tumor boards, second opinions, and ongoing surveillance gives him an intimate understanding of what patients and caregivers face. James asks the questions patients actually want answered because he’s wondered them himself. Show Notes - https://lcfamerica.org/wp-content/uploads/2026/04/LCFA-AMA-Scanxiety-Managing-Drug-Resistance-Fears-Notes.pdf Transcript - https://lcfamerica.org/wp-content/uploads/2026/04/LCFA-AMA-Drug-Resistance-Scanxiety-Transcript.pdf Watch the video - https://youtu.be/O6F_OLwjRHM
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Scanxiety: Managing Drug Resistance Fears with ALK+ Patient Jaymie Knox
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