The Microbiome's Impact on Health

Dr. Alessio Fasano, MD is Professor of Pediatrics at Harvard Medical School, Professor of Nutrition at Harvard T.H. Chan School of Public Health, and Director of the Mucosal Immunology and Biology Research Center at Massachusetts General Hospital in Boston, Massachusetts. Dr. Fasano’s translational science is focused on the role of impaired intestinal barrier function in the pathogenesis of autoimmune and inflammatory diseases, including celiac disease, autism and type 1 diabetes. Director of the Center for Celiac Research and Treatment at (MGHfC), Dr. Fasano is widely sought after as an expert in celiac disease, intestinal permeability and autoimmune disorders. 00:00 Introduction03:02 Ancient microbiome evidence04:38 Evolutionary mismatches in modern human microbiome08:37 Differences in hunter gatherer vs civilized health11:38 Factors in disease15:48 Zonulin17:55 Microbes affecting intestinal permeability19:01 Antibiotics24:18 How to maintain healthy microbiome27:07 Treating disease with nutrition33:36 How do we build health starting as children36:19 Changing the culture towards health38:56 Microbiome connection to child behavioral disorders41:33 We’re still learning about microbiome This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit ancestralhealth.substack.com