📝 "What Are Key Characteristics Of The Juvenile Ossifying Fibroma?"

Quick Review #278 - #pathology #oralpathology #doctorgallagher #oralsurgery #oralsurgeon #dentist #dentistry #dental - 5.13.25Location:- Most commonly involves the maxilla, mandible, paranasal sinuses, or orbit.- Maxilla is more frequently involved in the trabecular variant, while the psammomatoid variant commonly affects the orbit and paranasal sinuses.Demographics:- Occurs predominantly in children and adolescents (generally under age 15–20).- No strong sex predilection, but some studies note a slight male predilection.Radiographic Appearance:- Well-circumscribed expansile radiolucent lesion, may show varying degrees of internal radiopacity due to mineralization.- Cortical thinning and expansion are common; lesion may appear multilocular.- The borders are typically well defined, sometimes with a sclerotic rim.Histopathology:2 main variants:1 - Trabecular JOF: Characterized by trabeculae of immature woven bone in a cellular fibrous stroma.2 - Psammomatoid JOF: Features small, round ossicles (psammoma-like bodies) in a fibrous stroma.- Highly cellular, mitotic figures may be seen but no malignancy.Variants:- Trabecular Juvenile Ossifying Fibroma (TrJOF)- Psammomatoid Juvenile Ossifying Fibroma (PsJOF)Differential Diagnosis:1. Fibrous dysplasia2. Conventional ossifying fibroma3. Aneurysmal bone cyst4. Cemento-ossifying fibroma5. Osteoblastoma6. Low-grade osteosarcoma (due to aggressive growth in some cases)Management:A) Surgical excision or enucleation with curettage is the mainstay.B) Requires long-term follow-up due to high recurrence rates (up to 30–50% in some cases).C) In aggressive or recurrent cases, more extensive resection may be necessary.References:1. Merritt, H. A. (n.d.). Clinical findings in our patient with juvenile ossifying fibroma: a Coronal CT scan with contrast showing bilateral maxillary and right mandibular bone lesions [Figure]. ResearchGate.2. Gautier, B., Dugast, S., Guyonvarc'h, P., Longis, J., Corre, P., & Bertin, H. (2024).Ossifying fibroma and juvenile ossifying fibroma: A systematic review on clinical and radiological parameters, treatment modalities, and recurrence. Journal of Stomatology, Oral and Maxillofacial Surgery, 125(3), 102185.3. Titinchi, F. (2021).Juvenile ossifying fibroma of the maxillofacial region: A multi-center retrospective study. Journal of Oral and Maxillofacial Surgery, 79(8), 1672.e1–1672.e9.4. ChatGPT.2025#podcast #dentalpodcast #doctorgallagherpodcast #doctorgallagherspodcast #doctor #dentist #dentistry #oralsurgery #dental #dentalschool #dentalstudent #doctorlife #dentistlife #oralsurgeon #doctorgallagher