EPISODE · Feb 1, 2026 · 18 MIN
When Metabolism Fails the Foot: Insulin Resistance, Hypertension & Non‑Healing Ulcers
from Diabetic Foot Files · host Diabetic Foot Files
In this episode of Diabetic Foot Files Dr. G traces diabetic foot ulcers upstream to metabolic causes: insulin resistance and chronic hyperinsulinemia drive sodium retention, sympathetic overactivity, RAS activation and endothelial dysfunction that produce microvascular collapse and poor wound healing. Learn why clean-looking wounds still won’t close, how to target root causes (lifestyle, medications, supplements, and team-based care), and why limb salvage starts with restoring metabolism and vascular health—not just surface treatment.
What this episode covers
In this episode of Diabetic Foot Files Dr. G traces diabetic foot ulcers upstream to metabolic causes: insulin resistance and chronic hyperinsulinemia drive sodium retention, sympathetic overactivity, RAS activation and endothelial dysfunction that produce microvascular collapse and poor wound healing.Learn why clean-looking wounds still won’t close, how to target root causes (lifestyle, medications, supplements, and team-based care), and why limb salvage starts with restoring metabolism and vascular health—not just surface treatment.
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When Metabolism Fails the Foot: Insulin Resistance, Hypertension & Non‑Healing Ulcers
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