EPISODE · May 28, 2026 · 29 MIN
Your Fat Cells Just Walked Off the Job. Here's Who Got Left Holding the Bag.
from The Habit Healers · host Laurie Marbas, MD, MBA
Can someone at 220 pounds be metabolically healthier than someone at 155? In this episode, I explain why the real driver of type 2 diabetes and insulin resistance isn’t how much fat you carry, but whether you’ve exceeded your own personal fat storage capacity.I walk you through what I call the garage model of metabolic health: the idea that your fat tissue has a fixed number of parking spaces, and trouble begins only when that garage fills up and fat starts spilling into your liver, muscles, and the space around your organs. This is where fatty liver disease, rising triglycerides, and high blood sugar actually come from. I break down the cascade one domino at a time, from overloaded fat cells to visceral fat, to a fatty insulin-resistant liver, to the cholesterol changes that standard testing often misses.Then comes the hopeful part. I explain why this cascade reverses in a predictable order, why your pancreas may be recovering rather than failing, and why diabetes remission depends far more on losing enough weight than on where you started.What you’ll learn:* Why metabolically healthy obesity and thin people with high blood sugar both come down to fat storage capacity* How visceral fat and fatty liver disease quietly drive insulin resistance* Why your triglyceride-to-HDL ratio and ApoB can catch problems years before a glucose test* The order in which liver, lipids, and the pancreas recover during diabetes reversalWhich blood markers and labs to request, including HOMA-IRCheck out the Habit Healers Community: https://www.skool.com/habithealers/aboutDr. Marbas Substack Article: https://drlauriemarbas.substack.com/p/your-fat-cells-just-walked-off-the Get full access to The Habit Healers at drlauriemarbas.substack.com/subscribe
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Your Fat Cells Just Walked Off the Job. Here's Who Got Left Holding the Bag.
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