Dr. John Campbell podcast artwork

PODCAST · education

Dr. John Campbell

Hello Everyone,My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/Twitter, https://twitter.com/JohnincarlisleDisclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health car

  1. 324

    Helsinki

    Dr. Aseem Malhotra, direct link to expert testimony in Finland https://casecovidpass.com/wp-content/uploads/2024/04/Dr-Aseem-Malhotra-testimony-before-Helsinki-District-Court-12-April-2024-in-Finland-MPXjVFzs8dE.mp3 Learn more about your ad choices. Visit megaphone.fm/adchoices

  2. 323

    Record excess deaths in Europe

    European Union, Excess mortality hits +16%, highest 2022 value so far UK latest excess death data, updated 16th September https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregisteredweeklyinenglandandwalesprovisional/weekending2september2022 https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19/latestinsights WE 2nd September 350 deaths involving COVID-19 (505 deaths registered, previous week) Total number of deaths registered in the UK 10,198, which was 7.4% above the five-year average 706 excess deaths in the week (Deaths involving COVID-19 accounted for 3.4% of all deaths) Excess mortality hits +16%, highest 2022 value so far https://ec.europa.eu/eurostat/web/products-eurostat-news/-/ddn-20220916-1 Update, 16th September Data for July Climbed to +16% in July 2022 Highest so far in 2022 June, +7% May. +7% July, additional deaths The increase of 16% = 53, 000 additional deaths in July (Compared with monthly averages, 2016-2019) Factors Post covid infection Covid sequala Post lockdown effects, social, psychological, psychiatric Reluctance to access health care during covid Delayed diagnosis Heat waves July 2022 Iceland, + 55.8% Spain +37% Cyprus +33% Greece +31% Portugal, +28.8% Switzerland, +25.9% Italy, + 24.9 Austria, + 17.5% Slovenia, + 16.5% Ireland, + 16.3% Germany, +15.2 Norway + 14.8% Netherlands, + 14.7% Croatia, + 14.6% France, + 14.1% Estonia + 12.3% Luxemburg + 11.%% Denmark +10.3% Latvia -0.5% https://app.powerbi.com/view?r=eyJrIjoiYmUwNmFhMjYtNGZhYS00NDk2LWFlMTAtOTg0OGNhNmFiNGM0IiwidCI6ImVlNGUxNDk5LTRhMzUtNGIyZS1hZDQ3LTVmM2NmOWRlODY2NiIsImMiOjh9 UK, 0 to 24 25 to 49 50 to 64 85 + Causes of non-covid excess deaths, UK https://app.powerbi.com/view?r=eyJrIjoiYmUwNmFhMjYtNGZhYS00NDk2LWFlMTAtOTg0OGNhNmFiNGM0IiwidCI6ImVlNGUxNDk5LTRhMzUtNGIyZS1hZDQ3LTVmM2NmOWRlODY2NiIsImMiOjh9 Proximal causes Distal causes more difficult to identify Ischaemic heart disease Cerebrovascular disease Other circulatory disease Heart failure (marked increase) Cancer Acute respiratory Chronic respiratory Urinary Cirrhosis Diabetes Parkinson’s Learn more about your ad choices. Visit megaphone.fm/adchoices

  3. 322

    What is a jab

    Third part of this excellent talk with Professor Robert Clancy, doctor, immunologist, consultant physician, professor of pathology and professor of medicine, highly published medical researcher, author, teacher, doctor of science, doctor of philosophy, holder of the Australia Medal. Link to buy the book, https://covidthroughoureyes.com.au/products/covid-through-our-eyes-an-australian-story-of-mistakes-mistreatment-and-misinformation Learn more about your ad choices. Visit megaphone.fm/adchoices

  4. 321

    Chinese vaccine contrasts

    Chinese and Western vaccines compared https://www.bbc.co.uk/news/world-asia-china-63855508 Big changes, all of a sudden Live with the virus Vice-premier, Sun Chunlan China entering a new situation Virus ability to cause disease weakening Lifting most severe Covid policies End of quarantine camps People can isolate at home No more family separations Close contacts not taken to camps Strict ban on blocking fire exits No need to show tests for venues Less rules on internal travel Lateral flow tests to replace PCR tests in most areas Lockdowns continue in smaller more targeted areas Foreign travel soon Cases, 30,000 + Now Everyone will be exposed Will the medical system will be overwhelmed? National Health Commission All localities, focus on improving the vaccination rate of people aged 60-79, accelerating the vaccination rate of people aged 80 and above, and making special arrangements Prof Ivan Hung, Hong Kong University The main way for China to exit Covid with the least damage is via vaccination and three doses of vaccination is a must Hopefully before Chinese New Year (January 22) Rabbit Sinopharm Strategic Advisory Group of Experts on Immunization (SAGE) https://www.who.int/news-room/feature-stories/detail/the-sinopharm-covid-19-vaccine-what-you-need-to-know The vaccine is safe and effective for all individuals aged 18 and above. Individuals may choose to delay vaccination for 3 months following the infection. An inactivated vaccine with adjuvant (that is routinely used in many other vaccines) with a documented good safety profile, including in pregnant women. Symptomatic SARS-CoV-2 infection and efficacy against hospitalization 79% Does it prevent infection and transmission? No substantive data Does it work against new variants of SARS- CoV-2 virus? SAGE currently recommends using this vaccine Not yet been evaluated in the context of circulation of widespread variants of concern. How does this vaccine compare to other vaccines already in use? We cannot compare the vaccines head-to-head, (different approaches taken in designing the respective studies) but overall, all of the vaccines that have achieved WHO Emergency Use Listing, are highly effective in preventing severe disease and hospitalization due to COVID-19. Comparison with Western vaccines Pfizer original paper https://www.nejm.org/doi/full/10.1056/NEJMoa2034577 https://www.nejm.org/doi/suppl/10.1056/NEJMoa2034577/suppl_file/nejmoa2034577_appendix.pdf BNT162b2 was 95% effective in preventing Covid-19 Later analysis from Efficacy and effectiveness of covid-19 vaccine - absolute vs. relative risk reduction https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9115787/ AAR, Pfizer, during the trial period, 0.84% AAR https://patient.info/news-and-features/calculating-absolute-risk-and-relative-risk Absolute risk of a disease is your risk of developing the disease over a time period. Five to six-months update, AAR BNT162b2 3.7% mRNA1273 (Moderna-NIH) 4.9% Learn more about your ad choices. Visit megaphone.fm/adchoices

  5. 320

    Omicron reigns in US

    Omicron, US, 75% of cases, but what will this mean, is it good or bad Wefwafwa’s Medical videos channel https://www.youtube.com/channel/UCzsLklGgOttU3Se-WGLp7ow In case you want to support our community outreach programs please Use, (all donations go directly to the Uganda) patreon:https://www.patreon.com/awmedicalvideos Donate: SENDWAVE/ WorldRemit/Wise transfer/money Gram Mobile money number:+256785698803 Country: Uganda Registered name : Wefwafwa Andrew State: Eastern uganda Zip code:0000 Wallet Service provider:MTN City: Mbale city email me when you send on [email protected] US cases https://covid.cdc.gov/covid-data-tracker/#trends_dailycases US, in hospital https://covid.cdc.gov/covid-data-tracker/#hospitalizations Omicron in the United States https://www.cdc.gov/coronavirus/2019-ncov/variants/omicron-variant.html We don’t yet know how easily it spreads, Scientific Pandemic Influenza Group on Modelling, Operational https://www.gov.uk/government/publications/spi-m-o-consensus-statement-on-covid-19-15-december-2021/spi-m-o-consensus-statement-on-covid-19-15-december-2021 Omicron doubling time of around 2 days. Report 49 - Growth, population distribution and immune escape of Omicron in England https://www.imperial.ac.uk/mrc-global-infectious-disease-analysis/covid-19/report-49-Omicron/ Omicron, a 5.41 fold higher risk of reinfection compared with Delta. the severity of illness it causes, Omicron and cold-like symptoms rapidly taking over in London https://covid.joinzoe.com/post/omicron-and-cold-like-symptoms-rapidly-taking-over-in-london https://covid.joinzoe.com/post/omicron-and-cold-like-symptoms-rapidly-taking-over-in-london The top five symptoms reported in the ZOE app runny nose headache fatigue (either mild or severe) sneezing sore throat SA Patients presentations Blocked or runny nose Headache Tiredness Scratchy or sore throat Body aches or how well available vaccines and medications work against it. https://www.discovery.co.za/corporate/news-room https://www.discovery.co.za/corporate/news-room Two doses of the Pfizer 33% protection against infection with omicron, relative to the unvaccinated (down from 80% protection against infection with delta) 70% protection against hospital admission in omicron infection, relative to the unvaccinated (down from 93% protection with delta) US, Omicron growth https://covid.cdc.gov/covid-data-tracker/#variant-proportions UK, Omicron, UK data https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1043089/20211221_OS_Daily_Omicron_Overview.pdf UK confirmed omicron cases, + 15,363 = 60,508 SGTF confirmed cases, + 18,656 = 143,242 In UK hospitals and omicron diagnoses, 133 UK Omicron deaths, 14 UK data https://www.gov.uk/government/publications/covid-19-omicron-daily-overview https://covid.joinzoe.com/data#levels-over-time SA data https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/surveillance-reports/daily-hospital-surveillance-datcov-report/ https://www.telegraph.co.uk/global-health/science-and-disease/covid-19-hospitalisations-fall-sharply-south-africa/ Gauteng cases + 10,000 + 8,000 Professor Tom Moultrie, demographer, University of Cape Town It really does seem as if…my country will escape relatively unscathed in this wave What if South Africa's ‘light escape’…is because we ‘bought’ that present at horrendous cost during past waves Johannesburg and Pretoria workers going home by minibus Limit of 22 passengers Africa Could go one of two ways Omicron spreading, Eastern, Western, Central and Southern Africa. Kenya, Nigeria, the Democratic Republic of Congo, Zimbabwe, Namibia, Botswana, Malawi, Zambia Learn more about your ad choices. Visit megaphone.fm/adchoices

  6. 319

    New constructive ivermectin evidence

    A Pilot, Randomised, Placebo-Controlled, Double-Blind Trial of a Single Oral Dose of Ivermectin for Post-Exposure Prophylaxis of SARS-CoV-2 https://www.mdpi.com/1999-4923/17/9/1205 People who took one small oral dose of ivermectin after exposure, took longer to test positive and had more time alive and free of symptoms. Multiple reports from in vitro infectious models document Ivermectin’s antiviral properties https://pmc.ncbi.nlm.nih.gov/articles/PMC7564151/pdf/cells-09-02100.pdf Ivermectin has broad-spectrum antiviral activity. Randomised, double-blind, placebo-controlled Single oral dose of Ivermectin as prophylaxis for SARS-CoV-2 Trial to evaluate the effectiveness of a single oral low dose of Ivermectin Ability to prevent SARS-CoV-2 infection? Ability to reduce symptoms if infection did occur? Methods Asymptomatic community-dwelling adults Enrolled within 72 h of close contact with a case of SARS-CoV-2. Single oral 200 µg/kg dose of Ivermectin or placebo. 65Kg woman given 13mg 80Kg man given 16mg The primary outcome Conversion to a positive PCR or RAT test within 14 days of close contact. Secondary outcomes (for those who tested positive) Days alive free of symptoms in the 14 and 28 days following ivermectin Days from close contact until a positive PCR or RAT Results N = 536 (86 met inclusion criteria and were randomised) 68 adhered and were included in the analysis. Ivermectin arm 11/36 tested positive Placebo arm 11/32 tested positive So, ivermectin did not prevent people testing positive Days from close contact until a positive PCR or RAT Increased by 2.3 days in ivermectin group. P = 0.033 So, ivermectin lengthened the incubation period Viral load needed to precipitate clinical disease took longer to develop – indicating an antiviral effect. Infection may have been prevented from primary contact, - indicating an antiviral effect. Days alive free of symptoms Increased by 2.5 days in ivermectin group. P = 0.036 So ivermectin delayed onset of symptoms in people who tested positive (Longer asymptomatic period) Controlling included Age, prior SARS-CoV-2 infection, body mass index, hypertension, lung disease Conclusions We did not demonstrate that a single oral low dose of Ivermectin administered to asymptomatic adults within 72 h of close contact with a case of SARS-CoV-2 prevents conversion to a positive PCR or RAT. (may have done with a larger sample size) Amongst those who did convert to a positive PCR or RAT Ivermectin significantly lengthened the time from close contact to conversion Ivermectin increased the number of days alive free of symptoms More details Initiation of this trial in late 2021 Discovery in 1975 Massively used around the world Nobel Prize in 2015 Very low incidence of serious adverse side effects No instance of resistance reported in over 25 years. Ivermectin can bind to and inhibit the nuclear transport roles of the host importin α (IMPα) protein, which is known to mediate the nuclear import of various viral proteins and key host factors. Other quite distinct antiviral actions of Ivermectin have been proposed High (therapeutic) concentrations collect in the lungs, stable for more than 30 days in cattle Trial was based on the strong clinical retrospective association of statistically significantly lower mortality in patients who received oral Ivermectin (200 μg/kg) compared with usual care https://www.sciencedirect.com/science/article/pii/S0012369220348984 Ivermectin patients 15% mortality Controls, 25.2% mortality In subjects with severe pulmonary disease Ivermectin patients, mortality 38.8% Controls, 80.7% mortality Learn more about your ad choices. Visit megaphone.fm/adchoices

  7. 318

    Myocarditis paper

    With Dr. Peter McCullough and Nicolas Hulscher (paper authors). Autopsy findings in cases of fatal COVID-19 vaccine- induced myocarditis https://onlinelibrary.wiley.com/doi/full/10.1002/ehf2.14680 Myocarditis autopsy paper: https://onlinelibrary.wiley.com/doi/full/10.1002/ehf2.14680 VAERS myocarditis paper: https://journals.sagepub.com/doi/10.1177/20420986241226566 preprint autopsy paper: https://zenodo.org/records/8120771 Spike protein detoxification paper: https://www.cureus.com/articles/207654-clinical-approach-to-post-acute-sequelae-after-covid-19-infection-and-vaccination#!/ We will also cite the Nakahara paper and the Krausen paper https://pubmed.ncbi.nlm.nih.gov/37724969/ https://pubmed.ncbi.nlm.nih.gov/37758751/ Nic’s linkedIn: https://www.linkedin.com/in/nicolas-hulscher-3683b1274/ Learn more about your ad choices. Visit megaphone.fm/adchoices

  8. 317

    Egregious excess deaths

    Direct link to TV Parliament site, https://parliamentlive.tv/Event/Index/168f642a-5708-4b1a-9857-d8eacf475252 That this House has considered the covid-19 pandemic response and trends in excess deaths; and calls on the covid-19 inquiry to move onto its module 4 investigation into vaccines and therapeutics as soon as possible. We are witnesses to the greatest medical scandal in this country in living memory, and possibly ever: the excess deaths in 2022 and 2023. Its causes are complex, but the novel and untested medical treatment described as a covid vaccine is a large part of the problem. I have been called an anti-vaxxer, as if I have rejected those vaccines based on some ideology. I want to state clearly and unequivocally that I have not: in fact, I am double vaccinated and vaccine-harmed. Intelligent people must be able to tell when people are neither pro-vax nor anti-vax, but are against a product that does not work and causes enormous harm to a percentage of the people who take it. I am proud to be one of the few Members of Parliament with a science degree. It is a great shame that there are not more Members with a science background in this place; maybe if there were, there would be less reliance on Whips Office briefings and more independent research, and perhaps less group-think. I say to the House in all seriousness that this debate and others like it are going to be pored over by future generations, who will be genuinely agog that the evidence has been ignored for so long, that genuine concerns were disregarded, and that those raising them were gaslit, smeared and vilified. One does not need any science training at all to be horrified by officials deliberately hiding key data in this scandal, which is exactly what is going on. The Office for National Statistics used to release weekly data on deaths per 100,000 in vaccinated and unvaccinated populations—it no longer does so, and no one will explain why. The public have a right to that data. There have been calls from serious experts, whose requests I have amplified repeatedly in this House, for what is called record-level data to be anonymised and disclosed for analysis. That would allow meaningful analysis of deaths after vaccination, and settle once and for all the issue of whether those experimental treatments are responsible for the increase in excess deaths. Far more extensive and detailed data has already been released to the pharma companies from publicly funded bodies. Jenny Harries, head of the UK Health Security Agency, said that this anonymised, aggregate death by vaccination status data is “commercially sensitive” and should not be published. The public are being denied that data, which is unacceptable; yet again, data is hidden with impunity, just like in the Post Office scandal. Professor Harries has also endorsed a recent massive change to the calculation of the baseline population level used by the ONS to calculate excess deaths. It is now incredibly complex and opaque, and by sheer coincidence, it appears to show a massive excess of deaths in 2020 and 2021 and minimal excess deaths in 2023. Under the Toggle showing location of Column 505 old calculation method, tried and tested for decades, the excess death rate in 2023 was an astonishing 5%—long after the pandemic was over, at a time when we would expect a deficit in deaths because so many people had sadly died in previous years. Some 20,000 premature deaths in 2023 alone are now being airbrushed away through the new normal baseline. Shocking things happened during the pandemic response. In March 2020, the Government conducted a consultation exercise on whether people over a certain age or with certain disabilities should have “do not resuscitate” orders, known as DNRs, imposed upon them. A document summarising the proposals was circulated to doctors and hospitals; it was mistakenly treated as for Learn more about your ad choices. Visit megaphone.fm/adchoices

  9. 316

    Hydroxychloroquine and ivermectin

    Supressed repurposed drugs. Link to but the book, https://covidthroughoureyes.com.au/products/covid-through-our-eyes-an-australian-story-of-mistakes-mistreatment-and-misinformation Letters from Australia is Alison Bevege's Substack, https://lettersfromaustralia.substack.com/ Learn more about your ad choices. Visit megaphone.fm/adchoices

  10. 315

    Vaccine Bias Exposed: Deaths Reclassified!

    Deaths in people vaccinated for covid were recorded as ‘unvaccinated deaths’. Talk with Italian research scientist Dr. Panagis Polykretis Classification bias and impact of COVID-19 vaccination on all-cause mortality: the case of the Italian region Emilia-Romagna https://panagispolykretis.substack.com/p/this-paper-will-shock-the-world-unveiling https://www.tandfonline.com/doi/full/10.1080/08916934.2025.2562972#d1e410 Link to percentages data for number of deaths https://www.laverita.info/morti-no-vax-studio-2674340339.html Learn more about your ad choices. Visit megaphone.fm/adchoices

  11. 314

    Alternative facts

    Merck, Pfizer COVID-19 Antivirals Different From Ivermectin. Link for Richard, https://twitter.com/richjsimmonds https://www.factcheck.org/2021/10/scicheck-merck-pfizer-covid-19-antivirals-different-from-ivermectin/?fbclid=IwAR2YgSVzorIwnzLmtNfyBUXInsbuEw3bHf6ZVhyDlNtXp11SPL1orXz_bSs https://www.factcheck.org/our-staff/ is a journalist is a journalist who has covered government and politics Professor for Communication at University is a journalist who covered the media A journalist is a former assignment editor is a science journalist earned his B.A. in journalism worked as a reporter is a graduate of the Journalism School is a journalist SciCheck Digest The pills are very different from the antiparasitic medication ivermectin, Dubbed PF-07321332, the investigational medication is a protease inhibitor that blocks a key enzyme the SARS-CoV-2 virus needs to replicate itself. Molnupiravir While the results have not been published or peer-reviewed, they were compelling enough for the trial’s independent Data Monitoring Committee to recommend an early halt to recruitment into the study. Food and Drug Administration, an advisory committee to discuss the application on Nov. 30. Molnupiravir is a nucleoside analog — a drug that messes up viral replication by tricking the virus into using the processed medication as one of its building blocks for its genetic code. This is what’s known as “error catastrophe,” using a mechanism called “lethal mutagenesis.” Although both drugs are novel, with news of these developments, people on social media are spreading the false notion that the pills are the same or “suspiciously similar” to ivermectin Some iterations of the claim incorrectly posit that Pfizer’s drug is “based on” ivermectin and that the two are essentially the same because both are protease inhibitors — something that has not been established, and even if true, doesn’t mean the drugs are similar, That paper, (computational modeling paper published by some Indian scientists in March) however, does not show that ivermectin acts as a protease inhibitor against SARS-CoV-2 through any sort of biological experiment — it only proposes the possibility based on computer simulations. Drugs Shown to Inhibit SARS-CoV-2 in COVID-19 Open Access Disease: Comparative Basic and Clinical Pharmacology of Molnupiravir and Ivermectin https://austinpublishinggroup.com/pharmacology-therapeutics/fulltext/ajpt-v9-id1149.pdf It (ivermectin) is being repurposed as a therapeutic agent for COVID-19, after in vitro studies in Vero/hSLAM cells, showed that it caused a 5000-fold inhibition of SARS-CoV-2, The mechanisms of action of Ivermectin against SARS-CoV-2: An evidence-based clinical review article (Journal of antibiotics) http://dhakes.com/wp-content/uploads/2021/08/20210615-The-mechanisms-of-action-of-Ivermectin-against-SARS-CoV-2-An-evidence-based-clinical-review-article.pdf One such enzyme, 3 chymotrypsin-like proteases (3’cl pro/ Mpro) is responsible for working on this polyprotein causing other proteins to “librate” and carry out viral replication. Ivermectin binds to this enzyme and disrupts it. But the same is true of PF-07321332 Exploring the Binding Mechanism of PF-07321332 SARS-CoV-2 Protease Inhibitor through Molecular Dynamics and Binding Free Energy Simulations (20th August 2021) https://pubmed.ncbi.nlm.nih.gov/34502033/ The crystal structure of 3CLpro in complex with PF-07321332, lopinavir, and ritonavir is not yet available. Therefore, the docked complex of PF-07321332, lopinavir, and ritonavir with 3CLpro was generated using the Molecular operating environment (MOE) software. FB post “Looks like Merck is repackaging the ‘horse drug’ and making it much more expensive! It will be the ‘new’ treatment for C. in pill form,” The Food and Drug Administration has warned people against self-medicati Learn more about your ad choices. Visit megaphone.fm/adchoices

  12. 313

    Debunking the BBC debunk of ivermectin

    Ivermectin: How false science created a Covid 'miracle' drug https://www.bbc.co.uk/news/health-58170809 BBC Reality Check But the BBC can reveal there are serious errors in a number of key studies that the drug's promoters rely on. but thousands of supporters, many of them anti-vaccine activists, have continued to vigorously campaign for its use. Members of social media groups swap tips on getting hold of the drug, even advocating the versions used for animals https://www.nature.com/articles/s41591-021-01535-y Large pro-ivermectin Facebook groups have turned into forums for people to find advice on where to buy it, including preparations meant for animals. The BBC can reveal that more than a third of 26 major trials of the drug for use on Covid have serious errors or signs of potential fraud. The group of independent scientists examined virtually every randomised controlled trial (RCT) on ivermectin and Covid Social media group https://mobile.twitter.com/K_Sheldrick/status/1408651561228668931 https://cosmosmagazine.com/health/covid/data-detectives-ivermectin-studies/ That’s how they all met on Twitter They've been working together remotely on an informal and voluntary basis during the pandemic. Reference please The BBC can reveal that more than a third of 26 major trials of the drug for use on Covid have serious errors or signs of potential fraud. None of the rest show convincing evidence of ivermectin's effectiveness. Dr Kyle Sheldrick, one of the group investigating the studies, said they had not found "a single clinical trial" claiming to show that ivermectin prevented Covid deaths that did not contain "either obvious signs of fabrication or errors so critical they invalidate the study". Out of a total of 26 studies examined, there was evidence in five that the data may have been faked On top of these flawed trials, there were 14 authors of studies who failed to send data back. The independent scientists have flagged this as a possible indicator of fraud. The sample of research papers examined by the independent group also contains some high-quality studies from around the world. A recent study in Lebanon was found to have blocks of details of 11 patients that had been copied and pasted repeatedly they have submitted a retraction to the scientific journal which published it https://pubmed.ncbi.nlm.nih.gov/34073401/ Study from Iran Another study from Iran seemed to show that ivermectin prevented people dying from Covid. https://www.researchsquare.com/article/rs-109670/v1 The records of how much iron was in patients' blood contained numbers in a sequence that was unlikely to come up naturally. Dr Morteza Niaee, who led the Iran study, defended the results and the methodology and disagreed with problems pointed out to him, adding that it was "very normal to see such randomisation" when lots of different factors were considered Ivermectin is generally considered a safe drug, though there have been some reports of side effects. But indirect harm can come from giving people a false sense of security, especially if they choose ivermectin instead of seeking hospital treatment for Covid, or getting vaccinated in the first place. Some groups regularly contain posts about conspiracy theories of ivermectin cover-ups, as well as pushing anti-vaccine sentiment or encouraging patients to leave hospital if they aren't getting the drug. South African nurse dies Instead of consulting a doctor, she continued with the ivermectin and got home oxygen. What study are the BBC talking about? https://pubmed.ncbi.nlm.nih.gov/34552263/ https://www.nature.com/articles/s41591-021-01535-y https://www.medicalbrief.co.za/ivermectin-papers-show-limitations-of-inherently-unreliable-summary-data/ We recommend that meta-analysts who study interventions for COVID-19 should request and personally review IPD ( Learn more about your ad choices. Visit megaphone.fm/adchoices

  13. 312

    Shroud, Biblical and historic aspects

    Links for Rich, YouTube videos: "Biblical Mysteries Explained" https://www.youtube.com/@BiblicalMysteriesExplained Article sites: academia.edu, researchgate.net, richardsorensen.com, unholygrail.net/blog Watch this excellent film from David Rolfe, https://whocanhebe.com/Stream.html Watch this excellent film from David Rolfe, https://whocanhebe.com/Stream.html Link to download my PowerPoint, https://drjohncampbell.co.uk/ Shroud.com https://www.shroud.com/menu.htm Shroudphotos.com https://shroudphotos.com 3D Image https://shroud3d.com/introduction/3d-studies-of-the-shroud-of-turin-history/ Shroud fabric https://www.shroud.com/pdfs/ssi3233part3.pdf 3D reconstruction https://www.shroud.com/pdfs/ssi3233part3.pdf STURP conclusions https://www.shroud.com/78conclu.htm Study on radiocarbon result https://www.sciencedirect.com/science/article/abs/pii/S0040603104004745 New dating study on X ray scattering https://www.mdpi.com/2571-9408/5/2/47 Polon studies https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:210758-1 1. ca. 33 Jesus is crucified and buried by Nicodemus and Joseph of Arimathea, with burial cloth and tomb provided by the latter. Then Jesus rises from the dead. When the disciples enter the empty tomb, they see the burial cloths according to the Gospels. 2. ca 33-38 The burial cloth of Christ was said to be brought to Edessa by Thomas or Thaddeus at the request of King Abgar V of Edessa, who was miraculously healed. Edessa becomes a Christian city. A mosaic tile was made of face on the Shroud, known as the Keramion, and placed over the city gate. In addition to the Shroud, this tile may have been the model used for future pictures of Christ. 3. 57 Ma’nu VI becomes king of Edessa and reverts the city to paganism. The Shroud and the Keramion are hidden in the city walls to protect them from destruction, and the location was apparently forgotten. 4. 525 The Shroud and the Keramion are rediscovered during the rebuilding of Edessa after a flood. 5. 544 Edessa is besieged by a Persian army and the Shroud and/or the Keramion purportedly save the city. Following this, the Hagia Sophia church (named after its analog in Constantinople) is constructed to house and venerate the Shroud and the Keramion. The Shroud is shown to the public every Easter, but in an air of secrecy and mystery. In this era the appearance of Christ as depicted in Christian art suddenly changes from a smooth Greco-Roman style to a Semitic man, with the characteristics of the face from the Shroud and/or the Keramion. Syriac artists become the main source of Christian art. 6. 944 - 1204 The Byzantine emperor, Romanus Lacapenus sends an army to Edessa to capture the Shroud and bring it to Constantinople as a means of divine protection. The Shroud was received with great ceremony and paraded through the city – a copy of the sermon given by on that occasion still exists. The Shroud is kept in the imperial relic treasury and periodically presented to private audiences. 7. 1204 The knights of the 4th Crusade come to Constantinople, supposedly on their way to Jerusalem, but due to a complex and unfortunate series of political events, they sack Constantinople instead. The Shroud is taken by the crusaders. 8. 1204 – 1355 This period is known as the “missing years” of the Shroud. The explanation with the most documentary evidence is that the Shroud was given to or taken by the knight Othon de la Roche, a knight from the Burgundy region of France who became the Lord of Athens in Greece. The Shroud may have been in Greece but was eventually brought to Besançon, the capital of Burgundy. In any case the Shroud eventually became the property of Geoffrey de Charny and his family. Geoffrey de Charny, a Templar and high counselor to King John II of France, and the Lord of Lirey and Savoisy in France, had built a chapel in Lirey to commemorate his rescue from the Englis Learn more about your ad choices. Visit megaphone.fm/adchoices

  14. 311

    Who fact checks the fact checkers

    Now all of the facts were equal, but some facts were more equal than others. Institute for Scientific Freedom https://www.scientificfreedom.dk/strategy/?utm_source=substack&utm_medium=email 1 All science should strive to be free from financial conflicts of interest. 2 All science should be published as soon as possible and made freely accessible. 3 All scientific data, including study protocols, should be freely accessible, allowing others to do their own analyses. Open letter from BMJ to Facebook about inappropriate censoring of serious data integrity issues in Pfizer’s COVID-19 vaccine trial https://www.scientificfreedom.dk/2021/12/18/open-letter-from-bmj-to-facebook-about-inappropriate-censoring-of-serious-data-integrity-issues-in-pfizers-covid-19-vaccine-trial/ https://www.bmj.com/content/375/bmj.n2635/rr-80 Fiona Godlee, editor in chief Kamran Abbasi, incoming editor in chief The BMJ Competing interests: As current and incoming editors in chief, we are responsible for everything The BMJ contains. Dear Mark Zuckerberg, The BMJ, one of the world’s oldest and most influential general medical journals. https://www.bmj.com/about-bmj/history-of-the-bmj 3rd October 1840 Serious concerns about the “fact checking” being undertaken by third party providers on behalf of Facebook/Meta. In September, a former employee of Ventavia, a contract research company helping carry out the main Pfizer covid-19 vaccine trial, began providing The BMJ with dozens of internal company documents, photos, audio recordings, and emails. These materials revealed a host of poor clinical trial research practices occurring at Ventavia that could impact data integrity and patient safety. We also discovered that, despite receiving a direct complaint about these problems over a year ago, the FDA did not inspect Ventavia’s trial sites. The BMJ commissioned an investigative reporter to write up the story for our journal. The article was published on 2 November, (2021) following legal review, external peer review and subject to The BMJ’s usual high level editorial oversight and review. Covid-19: Researcher blows the whistle on data integrity issues in Pfizer’s vaccine trial https://www.bmj.com/content/375/bmj.n2635 But from November 10, readers began reporting a variety of problems when trying to share our article. Some reported being unable to share it. Many others reported having their posts flagged with a warning about “Missing context … Independent fact-checkers say this information could mislead people.” Those trying to post the article were informed by Facebook that people who repeatedly share “false information” might have their posts moved lower in Facebook’s News Feed. Group administrators where the article was shared received messages from Facebook informing them that such posts were “partly false.” Readers were directed to a “fact check” performed by a Facebook contractor named Lead Stories. Fact Check: The British Medical Journal Did NOT Reveal Disqualifying And Ignored Reports Of Flaws In Pfizer COVID-19 Vaccine Trials https://leadstories.com/hoax-alert/2021/11/fact-check-british-medical-journal-did-not-reveal-disqualifying-and-ignored-reports-of-flaws-in-pfizer-vaccine-trial.html We find the “fact check” performed by Lead Stories to be inaccurate, incompetent and irresponsible. – It fails to provide any assertions of fact that The BMJ article got wrong – It has a nonsensical title: “Fact Check: The British Medical Journal Did NOT Reveal Disqualifying And Ignored Reports Of Flaws In Pfizer COVID-19 Vaccine Trials” – The first paragraph inaccurately labels The BMJ a “news blog” – It contains a screenshot of our article with a stamp over it stating “Flaws Reviewed,” despite the Lead Stories article not identifying anything false or untrue in The BMJ article – It published the story on its website under a URL Learn more about your ad choices. Visit megaphone.fm/adchoices

  15. 310

    Births down, deaths up

    Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic https://journals.sagepub.com/doi/10.1177/09246479251353384 Vibeke and team, crowd funding, Me again - here is link to our crowdfunding - it would be great if you would link. https://buymeacoffee.com/batchdependency Observed Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics Limited data, relationship, COVID-19 vaccination status and birth rates. Objectives Nationwide data from the Czech Republic Rates of successful conceptions (SCs) (conceptions leading to live births 9 months later) For women who were either vaccinated or unvaccinated against COVID-19 before SC. Summary monthly COVID-19 vaccination and birth data Women in the Czech Republic aged 18–39 January 2021 to December 2023. Results 1,300,000 women aged 18–39 years in the Czech Republic Proportion of COVID-19-vaccinated women increased from January 2021 until reaching a steady state of around 70% by the end of 2021. At least from June 2021, SCs per 1000 women were considerably lower for women who were vaccinated, compared to those that were unvaccinated, before SC. SC rates for the vaccinated group were much lower than expected based on their proportion of the total population. Conclusions SC rates were substantially lower for women vaccinated against COVID-19 before SC than for those who were not vaccinated. These hypothesis-generating and preliminary results call for further studies of the potential influence of COVID-19 vaccination on human fecundability and fertility. Learn more about your ad choices. Visit megaphone.fm/adchoices

  16. 309

    Trip to Davos

    With Consultant Cardiologist, Dr. Aseem Malhotra, First do on Pharm, https://nopharmfilm.com/ https://www.imdb.com/title/tt33511587/ Aseem's work site, https://draseemmalhotra.co.uk/ Hope Accord link, https://thehopeaccord.org http://drjohncampbell.co.uk/C.mp4 Learn more about your ad choices. Visit megaphone.fm/adchoices

  17. 308

    Vitamin D levels advised

    Read the link to the original paper, https://www.mdpi.com/2072-6643/13/10/3596 Deficiency of vit D limits the performance of systems resulting in, increased spread of diseases of civilization Reduced protection against infections Reduced effectiveness of vaccination Covid fatality rates correlate with, Elderly, dark, black people, comorbidities, winter Blood level of 20 ng/mL, (50 nmol/L) sufficient to stop osteomalacia Preferable, 40–60 ng/mL (100 to 150 nmol/L) Vitamin D3 receptors Bone Intestine Pancreas Prostate Immune system cells Vitamin D is a powerful epigenetic regulator Influencing more than 2,500 genes Cancer Diabetes mellitus Acute respiratory tract infections Viral lung infections that cause ARDS Chronic inflammatory diseases Autoimmune diseases Multiple sclerosis Immunomodulatory properties Regulating innate and adaptive immune systems D3 receptors Monocytes/macrophages T cells B cells Natural killer (NK) cells Dendritic cells (DCs) Supplements Without calcium supplementation, even very high vitamin D3 supplementation does not cause vascular calcification Vitamin D3 supplementation in the range of 4000 to 10,000 units (100 to 250 µg) needed to generate an optimal 40–60 ng/mL (100 to 150 nmol/L) has been shown to be completely safe when combined with approximately 200 µg vitamin K2 https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-k/ However, this knowledge is still not widespread in the medical community, and obsolete warnings about the risks of vitamin D3 overdoses unfortunately are still commonly circulating. ARDS and cytokine release syndrome Vitamin D3 is able to inhibit the underlying metabolic pathways Vitamin D3 has a protective role against ARDS caused by SARS-CoV-2. A rapidly increasing number of publications are investigating the vitamin D3 status of SARS-CoV-2 patients, and have confirmed low vitamin D levels in cases of severe courses of infection and positive results of vitamin D3 treatments Conclusions we recommend raising serum 25(OH)D levels to above 50 ng/mL (100 to 150 nmol/L) to prevent or mitigate new outbreaks due to escape mutations or decreasing antibody activity. At a time when vaccination was not yet available, patients with sufficiently high D3 serum levels preceding the infection were highly unlikely to suffer a fatal outcome. This correlation should have been good news when vaccination was not available but instead was widely ignored. the lower threshold for healthy vitamin D levels should lie at approximately 125 nmol/L or 50 ng/mL 25(OH)D3, which would save most lives, reducing the impact even for patients with various comorbidities. This is—to our knowledge—the first study that aimed to determine an optimum D3 level to minimize COVID-19 mortality Implications for herd immunity It seems clear that a good immune defense, does not prove protection against physical infection but rather against its consequences This “protection” was most effective at ~55 ng/mL Traditionally living populations in East Africa have a mean serum 25-hydroxyvitamin D concentration of 115 nmol/l https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/traditionally-living-populations-in-east-africa-have-a-mean-serum-25hydroxyvitamin-d-concentration-of-115-nmoll/6188564A01361C5CF5F196229430E475 natural vitamin D3 levels seen among traditional hunter/gatherer lifestyles, in a highly infectious environment, were 110–125 nmol/L (45–50 ng/mL) WHO advice may not be correct 30 ng/mL D3 value considered by the WHO as the threshold for sufficiency Future mutations of the SARS-CoV-2 virus, vaccine immune escape the entire population should raise their serum vitamin D level to a safe level as soon as possible. As long as enough vitamin K2 is provided, the suggested D3 levels are entirely safe to achieve by supplementat Learn more about your ad choices. Visit megaphone.fm/adchoices

  18. 307

    Vitamin D, government inaction

    COVID-19 Mortality Risk Correlates Inversely with Vitamin D3 Status, a Mortality Rate Close to Zero Could Theoretically Be Achieved at 50 ng/mL 25(OH)D3: (125 nmol/L) Results of a Systematic Review and Meta-Analysis https://www.mdpi.com/2072-6643/13/10/3596 Blood calcifediol (25(OH)D3) levels correlate strongly with SARS-CoV-2 infection severity Cause or effect? Strength of our immune system, More or less neglected by the responsible authorities Nutrition, physical fitness, recreation, sleep Widespread vitamin D deficiency Data collected March 2021 Methods Systematic literature search Retrospective cohort studies (1) Clinical studies (7) on COVID-19 mortality rates versus D3 blood levels Reported D3 blood levels pre-infection or on the day of hospital admission Mortality rates, corrected for age, sex, and diabetes Results Negative Pearson correlation of D3 levels and mortality risk r = −0.4154, p = 0.0770 r = −0.4886, p = 0.0646 Combined data Median D3 levels were 23.2 ng/mL (58 nmol/L) Pearson correlation = −0.3989, p = 0.0194 Regression suggested a theoretical point of zero mortality at approximately 50 ng/mL (125 nmol/L) D3 Conclusions The datasets provide strong evidence that low D3 is a predictor rather than just a side effect of the infection. Despite ongoing vaccinations, we recommend raising serum 25(OH)D levels to above 50 ng/mL Learn more about your ad choices. Visit megaphone.fm/adchoices

  19. 306

    Cancer free after mushroom

    Isle of Wight mushroom farm, https://www.iwmushrooms.co.uk/ I have no commercial intrest in this but it is where I get my Lion's mane tuncture from and I visited the farm myself, on this video https://www.youtube.com/watch?v=1UTX8SFDlUM Learn more about your ad choices. Visit megaphone.fm/adchoices

  20. 305

    Low vitamin D and increased deaths

    Lower levels of vitamin D, higher rates of death Association of Serum 25-Hydroxyvitamin D Concentrations With All-Cause and Cause-Specific Mortality Among Adult Patients With Existing Cardiovascular Disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8496747/ Observational study, non-interventional Background Vitamin D, lower levels, common in patients with cardiovascular disease (CVD) Study of patients with existing CVD Prospectively examine the associations of serum 25-hydroxyvitamin D [25(OH)D] concentrations with, All-cause mortality and, cause-specific mortality Methods N = 37,079 patients with CVD from the UK Biobank study From a prospective cohort of half a million, aged 40–69 years https://www.ukbiobank.ac.uk CVD Coronary heart disease Atrial fibrillation Heart failure Stroke Results Among 37,079 patients with CVD at baseline, 57.5% were vitamin D deficient Deficient, 25[OH]D less than 50 nmol/L (less than 20ng/ml) Median follow-up of 11.7 years Deaths that occurred = 6,319 total 2,161 deaths from CVD 2,230 deaths from cancer 623 deaths from respiratory disease 1,305 other-cause deaths Non-linear inverse associations For all-cause mortality Cancer mortality Respiratory disease mortality Other-cause mortality That is deaths went up as vitamin D levels went down (P-non-linearity less than 0.01) Approximately linear inverse associations for CVD That is deaths went up as vitamin D levels went down (P-non-linearity = 0.074) Among CVD patients with vitamin D deficiency For every 10 nmol/L increment in serum 25(OH)D concentrations, There was an associated 12% reduced risk for all-cause mortality There was an associated 9% reduced risk for CVD mortality. In patients with vitamin D deficiency Per 10 nmol/L increase in serum 25(OH)D levels, was associated with a lower risk of mortality from (aHR]; 95% CI) All-cause 0.88 CVD 0.91 Cancer 0.90 Respiratory diseases 0.81 Other causes 0.81 Multivariable Cox regression models Age, sex, alcohol, BMI, GFR, education, ethnicity, household income, smoking status, healthy diet score, diabetes (and meds), HbA1c, duration of CVD, blood pressure (and meds), lipid profile (and meds), triglycerides, cholesterol Conclusion Among patients with existing CVD, increasing levels in serum 25(OH)D, were independently associated with a decreased risk of all-cause and cause-specific mortality These findings suggest that elevated serum 25(OH)D concentration benefits CVD patients with vitamin D deficiency. Therefore Patients with vitamin D deficiency may benefit more from an increase in serum levels, than those with CVD and serum 25(OH)D levels of less than 50 nmol/L (less than 20ng/ml) Our findings provided novel clues awaiting further validation in clinical trials. Learn more about your ad choices. Visit megaphone.fm/adchoices

  21. 304

    Rimmer's cancer cured?

    Isle of Wight mushroom farm, https://www.iwmushrooms.co.uk/ I have no commercial intrest in this but it is where I get my Lion's mane tuncture from and I visited the farm myself, on this video https://www.youtube.com/watch?v=1UTX8SFDlUM Learn more about your ad choices. Visit megaphone.fm/adchoices

  22. 303

    Most omicron hospitalisations unintended

    Around 80% of English hospital admissions with coronavirus are admitted for other reasons UK, 24th December Omicron hospital patients, 366 Total omicron deaths, 29 UK, 27th December Omicron hospital patients, 407 Total omicron deaths, 39 Omicron cases + 45,307 = 159,932 UK, 29th December Omicron hospital patients, + 261 + 98 = 766 Total omicron deaths, + 10 + 4 = 53 UK data https://www.gov.uk/government/publications/covid-19-omicron-daily-overview https://covid.joinzoe.com/data#levels-over-time https://coronavirus.data.gov.uk SA data SA hospital data https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/surveillance-reports/daily-hospital-surveillance-datcov-report/ https://www.worldometers.info/coronavirus/country/south-africa/ US cases and deaths data https://covid.cdc.gov/covid-data-tracker/#trends_dailycases Isolation down to 5 days is asymptomatic 20% of covid admissions caused by viral complications https://www.telegraph.co.uk/news/2021/12/28/covid-hospital-data-should-treated-caution-many-patients-admitted/ December 21, England Covid patients in hospital = 6,245 Up 259 from previous week Of the 259, just 45 admitted because of the virus Of the 259, admitted, 214 for other conditions but having also tested positive “incidental Covid” admissions Previous week, December 7 to December 14 Majority of hospitalisations were still delta Primary covid cases were 59% of the 289 weekly rise People currently in hospital with Covid “incidental” cases, 1,813 out of 6,245 Highest so far Sir John Bell, regius professor of medicine, Oxford University This is not the same disease we were seeing a year ago The horrific scenes that we saw a year ago – intensive care units being full, lots of people dying prematurely – that is now history in my view and I think…that’s likely to continue Chris Hopson, the chief executive of NHS Providers What our guys are saying is that incidental cases are making around 25 to 30 per cent of cases that are arriving, but that will vary from place to place In London you would expect to see higher levels lower in somewhere like the South West, where community infections are lower They are seeing an increase in the number of hospital admissions but it's not precipitous. It's not going up in an exponential way As the number of cases in the community rises, there are significant levels of incidental cases But we mustn't forget that having those people in hospital causes complications because of infection control measures under significant amounts of pressure and are struggling with high numbers of staff absences More cases of incidental Covid compared to previous waves Dr Raghib Ali, consultant in acute medicine at Oxford University Hospitals, There is certainly a smaller proportion of people ending up with Covid pneumonia in intensive care Probably half the cases I’ve seen are incidentals You’ve got completely incidental cases, someone coming in with a broken leg, who also tests positive for Covid, then a third category of older people who have comorbidities. Maybe they’ve had a fall or chest pain and also test positive and it's unclear if the virus is having some sort of impact. And when the prevalence of a virus with relatively mild symptoms is high in the community then you will see higher incidentals Similar to Gauteng, with 52% incidentals Report from Intensive Care National Audit and Research Centre (May 1 to Dec 24) https://www.dailymail.co.uk/news/article-10348763/Most-pregnant-women-ventilators-Covid-havent-jab.html https://www.icnarc.org/our-audit/audits/cmp/reports Learn more about your ad choices. Visit megaphone.fm/adchoices

  23. 302

    Endemic equilibrium cometh

    Virus is close to reaching “endemic equilibrium” Update on Balira Link to original Wefeafwa video https://www.youtube.com/watch?v=mV7a9MMFbRg&t=15s If you would like to support our community health outreach in Uganda (100% of donations go directly to Wefwafwa) patreon:https://www.patreon.com/awmedicalvideos Donate: SENDWAVE/ WorldRemit /Western Union/Money Gram Mobile money number:+256785698803 Country: Uganda Registered name : Wefwafwa Andrew State: Eastern uganda Zip code:0000 Wallet Service provider:MTN City: Mbale city please email me when you send or to talk with me directly, [email protected] London School of Hygiene and Tropical Medicine https://www.telegraph.co.uk/news/2021/10/24/coronavirus-cases-slump-winter-say-scientists/ Imminent drops in infections Cases could fall to around 5,000 a day before Christmas Prof John Edmunds, Centre for the Mathematical Modelling of Infectious Diseases, LSHTM Member of SAGE Our model was projecting that cases would start to decline some time in the autumn. However, the model also suggests that cases may start to climb again in the spring, due to a combination of waning immunity and increased contacts Cases currently being driven by high case rates in children Virus is close to reaching “endemic equilibrium” Recent oscillations in case rates will soon level Rishi Sunak at the moment the data does not suggest that we should be immediately moving to 'Plan B Maggie Throup, UK vaccines minister 'Plan A' is working, situation where we need to be United States Pfizer for children, 5 to 11, FDA votes for EMU tomorrow From first half of November 2 shots, 3 weeks gap One third of adult dose 25,000 centres signed up for roll out 28 million children in demographic https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-submit-initial-data-us-fda-pivotal https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-biontech-announce-positive-topline-results https://www.businesswire.com/news/home/20210920005452/en/ https://www.fda.gov/media/153447/download Results are the first from a pivotal trial of any COVID-19 vaccine in children under 12 years of age In participants 5 to 11 years of age, the vaccine was safe, well tolerated and showed robust neutralizing antibody responses Phase 2/3 study United States, Finland, Poland, Spain Children 6 months to 11 years of age N = 2,268 5 to 11 years of age Received a 10 µg dose level in a two-dose regimen Strong SARS-CoV-2–neutralizing antibody response, one month after the second dose Continue to accumulate the safety and efficacy data Topline readouts for the other two age cohorts from the trial, soon Children 2-5 years of age Children 6 months to 2 years of age About the Phase 1/2/3 Trial in Children N = 4,500 children ages 6 months to 11 years More than 90 clinical trial sites Children under 5 received a 3 µg dose Trial enrolled children with or without prior evidence of SARS-CoV-2 infection ONS https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19/latestinsights Reduction in self-reported long COVID after vaccination https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19vaccinationandselfreportedlongcovidintheuk/25october2021 Identified themselves as experiencing persistent symptoms 12 weeks after first infection A first vaccine dose was associated with an initial 13% decrease in self-reported long COVID, and a further 9% sustained decrease after receiving the second vaccination No evidence of differences in self-reported between Oxford/AstraZeneca vaccine, compared to Pfizer/BioNTech or Moderna vaccines UK, 30 June to 17 October 2021 Practice falls below thinking https://www.ons.gov.uk/peoplepopulationandcommunity/h Learn more about your ad choices. Visit megaphone.fm/adchoices

  24. 301

    New Hope Children's Centre

    This is a great organisation I have been involved with for 12 years now. I fully attest to the veracity and dedication of all the staff I have met. The founder is Anne Chege, who my brother and I know well. Anne worked with Barclays Bank for 28 years, looking after orphans and abandoned children within her own home. On retirement she opened this centre and has dedicated her life to the work. To contribute to this work, https://www.buymeacoffee.com/newhopechi3 Learn more about your ad choices. Visit megaphone.fm/adchoices

  25. 300

    Monkeypox, excellent news

    Monkeypox New Microbes and New Infections https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375638/ it is believed that African squirrels and other rodents might be the primary reservoirs Current epidemiological situation as of 10 October 2022 https://www.gov.uk/government/publications/monkeypox-outbreak-epidemiological-overview/monkeypox-outbreak-epidemiological-overview-11-october-2022 Confirmed cases, 3,523 Highly probable cases, 150 Scotland, 94 Northern Ireland, 34 Wales, 46 England, 3,499 Cases were confirmed in England from 6 May 2022 The outbreak has mainly been in gay, bisexual, and men who have sex with men, without documented history of travel to endemic countries. https://www.gov.uk/government/publications/monkeypox-outbreak-technical-briefings/investigation-into-monkeypox-outbreak-in-england-technical-briefing-8 Level 2 Transmission within a defined sub-population. Out of 3,390 cases with known gender, 99% are men, and there are 45 women. Nowcast and growth Incidence remains low. Multiple factors in reduction Vaccination, (moderate confidence) Behavioural modification, (low confidence) (Reduction in some other sexually transmitted infections) Route of transmission Close or sexual contact Monkeypox virus has been detected in air and environmental samples (hospital room of infected patients) No confirmed instances of airborne transmission Limited household transmission Assessment (confidence): Transmitting primarily through close or sexual contact (moderate) Observed clinical severity No reported deaths in the UK Morbidity amongst people admitted to hospital, severe pain, secondary bacterial infection Encephalitis, reported, appears uncommon US situation https://www.cdc.gov/poxvirus/monkeypox/response/2022/us-map.html Confirmed cases, as of 11th October 2022 = 26,778 Vaccinations = 873,552 (as of 4th October) UK ethnicity data US Ethnic mix https://www.medscape.com/viewarticle/982173?src=wnl_edit_tpal&uac=127834AR&impID=4739080&faf=1 Kaiser Family Foundation https://www.kff.org/racial-equity-and-health-policy/issue-brief/national-data-show-continuing-disparities-in-mpx-monkeypox-cases-and-vaccinations-among-black-and-hispanic-people/ MPX case rates among Black people are over five times those of White people (14.4 vs. 2.6 per 100,000) Hispanic people account for larger shares of cases compared with their shares of the population American Indian or Alaska Native Native Hawaiian or Other Pacific Islander Learn more about your ad choices. Visit megaphone.fm/adchoices

  26. 299

    DNA scientist discusses contamination

    With eminent DNA scientist and virologist, Dr. David J. Speicher. Quantification of residual plasmid DNA and SV40 promoter-enhancer sequences in Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada https://pubmed.ncbi.nlm.nih.gov/40913499/ 32 vials representing 16 unique vaccine lots. These data demonstrate the presence of billions to hundreds of billions of DNA molecules per dose in the modRNA COVID-19 products tested. All products tested exceeded the guidelines for residual DNA set by the FDA and WHO of 10ng/dose by 36–627-fold. Total DNA in all vials tested Exceeded the regulatory limit for residual DNA set by the US Food & Drug Administration (FDA) and the World Health Authorization (WHO) by: Pfizer: 36-153-fold Moderna: 112-627-fold 3 Pfizer vials exceeded the regulatory limit for the SV40 promoter-enhancer-ori (p53) The PCR results for the most recent XBB.1.5 Moderna and Pfizer vaccines suggest that DNA residues have not been reduced from previous vaccine versions. Pfizer, Total DNA ranged 371-1,548 ng/dose Moderna, 1,130-6,280 ng/dose Specific DNA of multiple plasmid DNA targets Pfizer ranged 0.22-7.28 ng/dose Moderna 0.01-0.78 ng/dose for Moderna. The SV40 promoter-enhancer-ori(0.25-23.72 ng/dose) was only detected in Pfizer vials. Sequencing of one vial Mean DNA length, 214 bp Maximum length, 3.5 kb Presence of 1.23 × 108 to 1.60 × 1011 plasmid DNA fragments per dose encapsulated in lipid nanoparticles. Our findings extend existing concerns about vaccine safety and call into question the relevance of guidelines conceived before the introduction of efficient transfection using LNPs. This work highlights the need for regulators and industry to adhere to the precautionary principle and provide sufficient and transparent evidence that products are safe and effective, and disclose the details of their composition and method of manufacture. For some of the COVID-19 vaccines, the drug substances released to market were manufactured differently than those used in clinical trials. Rationale for study Manufacturing nucleoside-modified mRNA for commercial COVID-19 vaccines relies on RNA polymerase transcription of a plasmid DNA template. Previous studies identified high levels of plasmid DNA in vials of mRNA vaccines, suggesting that the removal of residual DNA template is problematic. Therefore, we quantified the DNA load in a limited number of Pfizer-BioNTech and Moderna COVID-19 modRNA vaccine vials using two independent methods. This study emphasizes the importance of methodological considerations when quantifying residual plasmid DNA in modRNA products, considering increased LNP transfection efficiency, and cumulative dosing presents significant and unquantified risks to human health. Learn more about your ad choices. Visit megaphone.fm/adchoices

  27. 298

    Increases

    Professor Angus Dalgleish, (Fellow of the Royal College of Physicians, Fellow of the Royal College of Pathologists, Fellow of Medical Science.) Professor Dalgleish is a highly experienced doctor, physician, medical teacher, medical author and researcher with over 500 primary research publications. He was also a pioneering researcher into HIV/AIDS. Here we discuss the recently observed changes in cancer presentations and deaths. Some of the discussion considers this research paper noting excess cancer deaths in Japan. Increased Age-Adjusted Cancer Mortality After the Third mRNA-Lipid Nanoparticle Vaccine Dose During the COVID-19 Pandemic in Japan https://www.cureus.com/articles/196275-increased-age-adjusted-cancer-mortality-after-the-third-mrna-lipid-nanoparticle-vaccine-dose-during-the-covid-19-pandemic-in-japan#!/ Gibo M, Kojima S, Fujisawa A, et al. (April 08, 2024) Increased Age-Adjusted Cancer Mortality After the Third mRNA-Lipid Nanoparticle Vaccine Dose During the COVID-19 Pandemic in Japan. Cureus 16(4): e57860. DOI 10.7759/cureus.57860 Conclusions Statistically significant increases in age-adjusted mortality rates of all cancer and some specific types of cancer, namely, ovarian cancer, leukemia, prostate, lip/oral/pharyngeal, pancreatic, and breast cancers, were observed in 2022 after two-thirds of the Japanese population had received the third or later dose of SARS-CoV-2 mRNA-LNP vaccine. These particularly marked increases in mortality rates of these ERα-sensitive cancers may be attributable to several mechanisms of the mRNA-LNP vaccination, rather than COVID-19 infection itself or reduced cancer care due to the lockdown. Researchers have reported that the SARS-CoV-2 mRNA-LNP vaccine may pose the risk of development and progression of cancer. Several case reports have described cancer developing or worsening after vaccination and discussed possible causal links between cancer and mRNA-LNP vaccination. Learn more about your ad choices. Visit megaphone.fm/adchoices

  28. 297

    Omicron in the US, boosted transmissibility confirmed

    Omicron now in 24 countries and California. Now clear it is highly transmissible. Cases seem mild so far Omicron rapidly dominating in South Africa https://www.reuters.com/world/us-tightens-covid-19-travel-rules-countries-race-quell-omicron-threat-2021-12-01/ Omicron is rapidly becoming the dominant in South Africa Less than four weeks in South Africa's National Institute for Communicable Diseases (NICD) https://www.nicd.ac.za 74% of all genomes last month, omicron The first Omicron detected in the U.S. https://www.nytimes.com/2021/12/01/health/omicron-first-us-case-california.html California Wednesday, 1st December California from South Africa on 22nd November Mild symptoms started 25th November Mild symptoms that are improving Not hospitalized In isolation Aggressive contact tracing is underway Person fully vaccinated Had received two doses Moderna within the six-month window Close contacts have tested negative Dr. Anthony S. Fauci We have 60 million people in this country who are not vaccinated who are eligible to be vaccinated Let’s get them vaccinated. Let’s get the people vaccinated, boosted. Let’s get the children vaccinated. Get boosted now We may not need a variant-specific boost. (EU, vaccine rollout for five-to-11-year-olds 13th December) Dissent from Mike Ryan There is no evidence that I'm aware of that will suggest that boosting the entire population is going to necessarily provide any greater protection for otherwise healthy individuals against hospitalization or death WHO, coronavirus will keep producing new variants for as long as it is allowed to circulate freely in unvaccinated US https://www.reuters.com/world/us-tightens-covid-19-travel-rules-countries-race-quell-omicron-threat-2021-12-01/ Must have a negative test 24 hours prior to departure Learn more about your ad choices. Visit megaphone.fm/adchoices

  29. 296

    Covid, vaccines, malaria

    I have worked directly with Wefwafwa in rural Uganda, he is the real deal. If you buy him a coffee, he will not spend it on coffee. Buy me a coffee https://www.buymeacoffee.com/awmedicalvideos Patreon https://www.patreon.com/awmedicalvideos To contact Wefwafwa directly, [email protected] or WhatsApp+256756320736 YouTube channel, https://www.youtube.com/c/WefwafwaAndrew Learn more about your ad choices. Visit megaphone.fm/adchoices

  30. 295

    Chinese large-scale spread

    Download free high-res PDFs of the posters, download free copies of my two text books. Any donations using this link help the work of campbell teaching. https://drjohncampbell.co.uk/ My personal intake 4,000 iu vitamin D = 100 micrograms (with K2 100 micrograms per day) Both with food 15mg Zinc The Role of Zinc in Antiviral Immunity https://pubmed.ncbi.nlm.nih.gov/31305906/ An abundance of evidence has accumulated over the past 50 y to demonstrate the antiviral activity of zinc against a variety of viruses, and via numerous mechanisms. Varied, high plant diet Vitamin C, oranges and tomatoes China https://www.globaltimes.cn/page/202211/1280588.shtml https://asiatimes.com/2022/12/new-stealth-omicron-variant-spreading-fast-in-china/ Omicron, BF.7, (BA.5.2.1.7) Sub-lineage of omicron variant BA.5 Main variant spreading in Beijing https://www.chinadaily.com.cn/a/202211/29/WS63855959a31057c47eba1912.html Dr. Li, Chief physician, Beijing YouAn Hospital, Department of Infectious Diseases How infectious is the Omicron subvariant BF.7? Much more contagious than BA.1, BA.2, BA.5 Stronger immune evasion potential Shorter incubation period Faster transmission speed R0, (basic reproduction number) Delta strain, 5 to 6 BF.7 10 to 18.6 Most infectious omicron subvariant causing larger difficulty in epidemic prevention and control Why does the number of new infections keep growing in Beijing? People begin viral shedding one day after contract Second-generation cases may appear within two or three days (may be missed by testing) Time for infected people to turn negative is still about seven to 10 days. In addition Symptoms are generally mild Many infections show mild or no symptoms That's why it's important to find the infected and cut the transmission chain as soon as possible. Major symptoms Fever, coughing, sore throat, decreased sense of smell and taste. Diarrhea and vomiting (less common) Asymptomatic cases usually don't need medicine or medical treatment. High-risk groups Elderly Underlying diseases or weak immunity Smokers Obesity Later stages of pregnancy So we will monitor their situations more closely. Beijing, treats in accordance with symptoms Antipyretics and painkillers to help patients with fever or coughing. High risk to deteriorate, antiviral drugs Most asymptomatic cases, quarantined at home Are ordinary medical surgical masks still effective in preventing infection from the more contagious Omicron variant BF.7? Virus, mainly reproduces in the upper respiratory tract Able to spread the virus, coughing, speaking loudly Medical surgical masks are not as airtight and effective as N95 and KN95 masks Beijing, continue to make prevention and control measures more "scientific, rational, targeted and effective" https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing---14-december-2022 As we look to end this emergency, we still need to understand how it began. We continue to call on China to share the data and conduct the studies that we have requested, to better understand the origins of this virus. As I have said many times, all hypotheses remain on the table. One of the most important lessons of the pandemic is that all countries need to strengthen their public health systems to prepare for, prevent, detect and respond rapidly to outbreaks, epidemics and pandemics. An advanced medical care system is not the same thing as a strong public health system. One of the other key lessons of the pandemic is the need for much stronger cooperation and collaboration, rather than the competition and confusion that marked the global response to COVID-19. The global outbreak of mpox 82,000, 110 countries, 65 deaths Weekly reported cases, declined 90% since July. Ebola outbreak in Uganda No new cases in past 2 weeks Learn more about your ad choices. Visit megaphone.fm/adchoices

  31. 294

    White clots common

    With Major Tom Haviland Learn more about your ad choices. Visit megaphone.fm/adchoices

  32. 293

    Passing of science and covid

    Professor Angus Dalgleish, physician, oncologist, pathologist, medical researcher and author. Get your copy of The Death of Science, https://gazellebookservices.co.uk/pro... Also by Professor Dalgleish, The Origin of the Virus: The hidden truths behind the microbe that killed millions of people, https://www.amazon.co.uk/dp/185457106... Learn more about your ad choices. Visit megaphone.fm/adchoices

  33. 292

    Outstanding podcast with Hearts of Oak

    Original link, https://www.youtube.com/watch?v=YkRg5dyvGPE&t=2735s Check out Hearts of Oak, for some great talks, https://www.youtube.com/@UCy7r6GYTGA1gpHEZfqnscQA Learn more about your ad choices. Visit megaphone.fm/adchoices

  34. 291

    Omicron science, promising news

    New science explains South Africa's low rates of omicron severe disease SARS-CoV-2 spike T cell responses induced upon vaccination or infection remain robust against Omicron https://www.medrxiv.org/content/10.1101/2021.12.26.21268380v1 https://www.medrxiv.org/content/10.1101/2021.12.27.21268278v1 Institute of Infectious Disease and Molecular Medicine, University of Cape Town SARS-CoV-2 Omicron variant has multiple Spike (S) protein mutations These contribute to escape from the neutralizing antibody responses, reducing vaccine protection from infection We assessed the ability of T cells to react with Omicron spike In participants who were vaccinated with Ad26.CoV2.S (J and J) (n = 20) or BNT162b2 (Pfizer) (n = 15 or in unvaccinated convalescent COVID-19 patients (n = 15) SARS-CoV-2-specific T cells play a key role in modulating COVID-19 severity and provide protective immunity Results 70-80% of the CD4 and CD8 T cell response to spike was maintained across study groups The magnitude of Omicron cross-reactive T cells was similar to that of the Beta and Delta variants These results demonstrate that, despite Omicron’s extensive mutations and reduced susceptibility to neutralizing antibodies, the majority of T cell response, induced by vaccination or natural infection, cross- recognises the variant. Well-preserved T cell immunity to Omicron, is likely to contribute to protection from severe COVID-19, supporting early clinical observations from South Africa. Further explanation The limited effect of Omicron’s mutations on the T cell response suggests that vaccination or prior infection may still provide substantial protection from severe disease. Indeed, South Africa has reported a lower risk of hospitalisation and severe disease compared to the previous Delta wave Cross-reactive T cell responses acquired through vaccination or infection may contribute to these apparent milder outcomes for Omicron. The resilience of the T cell response demonstrated here also bodes well in the event that more highly mutated variants emerge in the future. Learn more about your ad choices. Visit megaphone.fm/adchoices

  35. 290

    POTUS, Pandemic is over

    The pandemic is over (POTUS) https://www.fda.gov/emergency-preparedness-and-response/coronavirus-disease-2019-covid-19/covid-19-vaccines Emergency use authorizations August 31, 2022 https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-moderna-pfizer-biontech-bivalent-covid-19-vaccines-use Today, the U.S. Food and Drug Administration amended the emergency use authorizations (EUAs) of the Moderna COVID-19 Vaccine, and the Pfizer-BioNTech COVID-19 Vaccine, to authorize bivalent formulations, for use as a single booster dose Original strain + BA.4 and BA.5 lineages For each bivalent COVID-19 vaccine, the FDA based its decision on the totality of available evidence, including extensive safety and effectiveness data for each of the monovalent mRNA COVID-19 vaccines, safety and immunogenicity data obtained from a clinical study of a bivalent COVID-19 vaccine that contained mRNA from omicron variant BA.1 lineage that is similar to each of the vaccines being authorized, Biden administration Has already placed an order for 170 million doses https://www.science.org/content/article/omicron-booster-shots-are-coming-lots-questions Data collected by the companies Human data, only available BA.1 booster BA.1 trails did not look for protection against severe disease, (People trials are very expensive) For the BA.4/BA.5 boosters, the companies have submitted animal data. (not released publicly) Pfizer presented preliminary findings in eight mice given BA.4/BA.5 vaccines as their third dose, (for EMA) Showed an increased antibody response to all Omicron variants tested: BA.1, BA.2, BA.2.12.1, BA.4, and BA.5. Clinical trials for the BA.4/BA.5 vaccines will begin this month August 19, 2022 https://www.fda.gov/news-events/press-announcements/fda-roundup-august-19-2022 Today, the FDA authorized the emergency use of Novavax COVID-19 Vaccine, in individuals 12 through 17 years of age. This authorization follows a rigorous analysis and evaluation of the safety and effectiveness data conducted by the FDA. July 13, 2022 https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-emergency-use-novavax-covid-19-vaccine-adjuvanted Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for the Novavax COVID-19 Vaccine, in individuals 18 years of age and older. June 17, 2022 https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-moderna-and-pfizer-biontech-covid-19-vaccines-children Today, the U.S. Food and Drug Administration authorized emergency use of the Moderna COVID-19 Vaccine and the Pfizer-BioNTech COVID-19 Vaccine, in children down to 6 months of age. December 22, 2021 https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-oral-antiviral-treatment-covid-19 Today, the U.S. Food and Drug Administration issued an emergency use authorization (EUA) for Pfizer’s Paxlovid Learn more about your ad choices. Visit megaphone.fm/adchoices

  36. 289

    Covid vaccine and automobile accidents

    Are people vaccinated against covid more protected from road accidents .... or not. COVID Vaccine Hesitancy and Risk of a Traffic Crash https://www.amjmed.com/article/S0002-9343(22)00822-1/fulltext Background Coronavirus disease (COVID) vaccine hesitancy, is a reflection of psychology that might also contribute to traffic safety. So People that take covid vaccines are the sort of people who have less traffic accidents People who do not take covid vaccines are the sort of people who have more traffic accidents Methods Population-based longitudinal cohort analysis of adults Determined COVID vaccination status from electronic medical records Traffic crashes requiring emergency medical care Subsequently identified accidents from all (178) hospitals One month follow-up Results, (2021) N = 11,270,763 Total traffic accidents, 6,682 Unvaccinated, 16% Vaccinated, 84% Unvaccinated individuals 1,682 traffic crashes (25%) Equal to a 72% increased relative Confidence interval, (95%) 63% to 82% (P less than 0.001) What about Socioeconomic status Alcohol Sleep apnea Diabetes Depression Dementia Hypertension Cancer Covid infection Equal to a 48% increase after adjustment Confidence interval, (95%) 40% to 57% (P less than 0.001) The increased risks extended across the spectrum of crash severity Results similar for Pfizer, Moderna, or other vaccines Conclusions These data suggest that COVID vaccine hesitancy is associated with significant increased risks of a traffic crash. An awareness of these risks might help to encourage more COVID vaccination. Factors Distrust of government Belief in freedom Misconceptions of everyday risks Faith in natural protection Antipathy toward regulation Chronic poverty Exposure to misinformation Political identity Negative past experiences Limited health literacy Social networks, misgivings around public health guidelines Primary care physicians who wish to help patients avoid becoming traffic statistics, could take the opportunity to stress standard safety reminders such as wearing a seatbelt, obeying speed limits, and never driving drunk Paramedics, should be aware that unvaccinated patients are overrepresented in the aftermath of a traffic crash. Driver insurance policies in the future Together, the findings suggest that unvaccinated adults need to be careful indoors with other people and outside with surrounding traffic. https://www.youtube.com/watch?v=_iryCrHaozU&t=174s But Unvaccinated in Canada could not use, planes, trains, buses https://www.forbes.com/sites/sandramacgregor/2021/08/18/canada-to-make-proof-of-vaccination-mandatory-for-air-and-train-travel/?sh=6569fb1fd465 Also https://covid19-sciencetable.ca/wp-content/uploads/2021/04/Science-Brief_Vaccines-in-Essential-Workers_20210423_published2.pdf Vaccinated more likely to work remotely in Ontario in 2021 ‘Essential workers’ had lower vaccination rates (several pile ups in ice and bad weather) Over 65s do not commute So Staying at home reduces the chances of being in an accident Invalid title Patient in emergency department as a driver, passenger, or pedestrian (codes V00-V69) Total = 6,682 Drivers, 2,856 Passengers, 1,189 Pedestrians, 2,637 (Table 3 of the study) (Therefore, unvaccinated pedestrians more likely to be in an accidents that vaccinated pedestrians) People were considered unvaccinated for the first 14 days after vaccination Given the study only lasted a month, this is half of the time. So how many casualties were misclassified? If 602 of the 6,682 were misclassified, Any difference between the two groups would vanish (Igor Chudov) https://igorchudov.substack.com/p/the-unvaccinated-had-more-car-crashes Deaths at Scene Excluded 42 deaths at scene 8 deaths were included (550 people were actually admitted to hospital) Therefore 84% of death outcomes ignored Learn more about your ad choices. Visit megaphone.fm/adchoices

  37. 288

    Viral transmission not tested in Pfizer trials

    Pfizer did not know whether Covid vaccine stopped transmission before rollout https://www.news.com.au/technology/science/human-body/pfizer-did-not-know-whether-covid-vaccine-stopped-transmission-before-rollout-executive-admits/news-story/f307f28f794e173ac017a62784fec414 https://www.youtube.com/watch?v=mnxlxzxoZx0 https://www.news.com.au/technology/science/human-body/pfizer-did-not-know-whether-covid-vaccine-stopped-transmission-before-rollout-executive-admits/news-story/f307f28f794e173ac017a62784fec414 Janine Small Pfizer’s president of international developed markets Testifying before the European Union Parliament, Monday 10th October Dutch MEP Rob Roos ‘Was the Pfizer Covid vaccine tested on stopping the transmission of the virus before it entered the market? If not, please say it clearly. If yes, are you willing to share the data with this committee? And I really want a straight answer, yes or no, and I’m looking forward to it.” Ms Small “Regarding the question around, um, did we know about stopping the immunisation before it entered the market? No Therefore Pfizer Covid vaccine was not tested on stopping the transmission of the virus before it entered the market Ms Small you know, we had to really move at the speed of science to really understand what is taking place in the market, and from that point of view we had to do everything at risk. I think Dr Bourla, even though he’s not here, would turn around and say to you himself, ‘If not us then who?’” Ms Small said Dr Bourla “actually felt the importance of what was going on in the world, and therefore as a result of that, we actually, um, spent $US2 billion, at risk, of self-funded money from Pfizer, to be able to research, develop and manufacture at risk, to be able to make sure that we were in a position to be able to help with the pandemic”. Mr Roos scandalous “Millions of people worldwide felt forced to get vaccinated because of the myth that ‘you do it for others’ “Now this turned out to be a cheap lie. This should be exposed.” YT Guidelines COVID-19 medical misinformation policy https://support.google.com/youtube/answer/9891785 Prevention misinformation: Content that promotes prevention methods that contradict local health authorities or WHO. https://support.google.com/youtube/answer/11161123 Efficacy of vaccines: content claiming that vaccines do not reduce transmission or contraction of disease Learn more about your ad choices. Visit megaphone.fm/adchoices

  38. 287

    Pandemic good news

    CDC variant report https://covid.cdc.gov/covid-data-tracker/#variant-proportions Some increase in BA.4.6 and BA.2.75 BA.4.6 Progressive US increase, starting to slowly displace BA.5 US of America (9,526) Canada (1,007) Denmark (500) France (400) Australia (288) Germany (248) Chile (242) Dominican Republic (173), Peru (149), Luxembourg (123), Belgium (102), Israel (101), Italy (94), Ireland (93), Sweden (92), Spain (85), Netherlands (84), Brazil (76), Argentina (68), Japan (67), New Zealand (60), Switzerland (54), Puerto Rico (53), South Africa (53), Ecuador (49), Mexico (35), Colombia (34), Trinidad and Tobago (30), Czech Republic (27), Costa Rica (23), Jamaica (21), Portugal (20), South Korea (19), Austria (17), Botswana (17), Indonesia (13), Sint Maarten (12), Senegal (11) BA.2.75 Some US increase Growth rate is currently 61% per week relative to co-circulating lineages Current US nowcast BA.5 84.8% (UK, 87.2%) BA.4.6 10.3% (UK, 3.3) BA.4 1.8% BF.7 1.7% BA.2.75 1.3% (UK, 1.6%) BA.2 0% (UK, 0.5%) BA.1s 0% Delta 0% Others 0% (UK, 2.4%) XE 0% UK, technical briefing 45 (September 2022) https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1103869/Technical-Briefing-45-9September2022.pdf Contains early data and analysis on emerging variants Findings have a high level of uncertainty Data cut-off of 5 September 2022 BA.5 BA.5 is the predominant circulating variant in the United Kingdom Newly designated variant – V-22SEP-01 (BA.4.6) Omicron sub-lineage BA.4.6 An apparent small growth advantage relative to BA.5. BA.4.6 represented 3.31% of UK samples Preliminary neutralisation data from BA.4.6 Expect some immune escape from BA.4 or BA.5 antibodies There is NO increased risk of hospital admission after BA.4 or BA.5 infection compared to BA.2 infection. Expect some immune escape triple dosed recipients of the Pfizer BNT162b2 vaccine. V-22JUL-01 (BA.2.75) As of 6 September 2022 BA.2.75 in the UK, 1.6% Does seem to have growth advantage over co-circulating lineages of, 61% per week Two sub-lineages of BA.2.75 (BA.2.75.1 and BA.2.75.2) are currently being assessed BA.4/BA.5 Severity A case-control study Risk of being admitted to hospital as an inpatient Among people presenting to emergency care within 14 days of positive test. Comparison, risk of admission with BA.4 or BA.5 versus BA.2 Between 16 March 2022 and 23 August 2022 BA.4 n = 2,530 BA.5 n = 12,026 BA.2 n = 17,022 Adjusted for age, sex, vaccination status, week of test, 2 days of extreme heat There was no difference in the risk of admission between people infected with BA.4 compared to BA.2 There was no difference in the risk of admission between people infected with BA.5 compared to BA.2 Learn more about your ad choices. Visit megaphone.fm/adchoices

  39. 286

    Excess deaths and data void

    Original video link https://parliamentlive.tv/Event/Index/168f642a-5708-4b1a-9857-d8eacf475252 Hansard link https://hansard.parliament.uk/Commons/2024-04-18/debates/9F01F787-D758-43D4-B8D1-4FA357EB3EED/Covid-19ResponseAndExcessDeaths We know, by all the different measures, that many more people are dying now than were before the pandemic. In particular, the impact on people’s hearts, and increasingly younger people’s hearts, deserves attention. The British Heart Foundation reported last June that since the start of the pandemic, 100,000 more people have died than would have been expected. That is surely significant cause for us to take this question seriously. We know that there are adverse effects from the vaccination. Everybody acknowledges that; it is a question of the extent to which those effects have been manifested. I am afraid, is that the MHRA is significantly deficient in the way it operates. The Cumberlege report—this was referenced in the earlier debate—raised concerns about the way treatments are regulated and licensed that have not yet been addressed. I am afraid that through the covid episode many of the same concerns were manifested in relation to the vaccines. We now know that the MHRA knew about the effect of the AstraZeneca vaccine on blood clotting as early as February 2021, but issued a warning about that only some months later—in April, a month after other countries had suspended the AZ vaccine. The MHRA also knew about the prevalence of heart problems and myocarditis in February 2021 but did nothing about it until June that year. In the intervening time, millions of people were vaccinated without the knowledge that the MHRA had. As has been said, we found out recently that Pfizer misrepresented the safety and efficacy of the vaccine. There has been very little comeback against it for that, and no meaningful fine. As we heard, just a few thousands pounds were charged in expenses. The regulatory system that oversees the pharmaceutical companies is surely deeply conflicted, not least due to being partly funded by the pharmaceutical companies that it was set up to represent. It is significant and of concern that they have made so much money out of the vaccines, and so far do not appear to be making due recompense for some of the acknowledged harms— I am not talking about the wilder claims—that their vaccines have been responsible for. Will the Minister enlighten us on whether the indemnities against civil and Government action that the Government awarded to the vaccine manufacturers at the beginning of the production process still apply if it transpires that the companies misled the Government and the public about the safety and efficacy of their product? The inquiry has been mentioned. There are so many unanswered questions and apparent red flags that it surprises me that the media and Parliament are not more up in arms about excess deaths. I am surprised that more attention is not being paid to this question. The fact is that this scandal—if it is a scandal—suits no one in high places in our country. It is true that we have an inquiry, but as the hon. Member for Blackley and Broughton said, surely it is asking the wrong questions. It is very concerning that the module looking at the vaccination programme has been postponed. It strikes me that the inquiry is essentially asking the wrong questions; it is really just asking why we did not do more lockdowns quicker. That seems to be its prevailing question for the experts—not whether the whole response was the right one, and crucially, in the light of what we now know, whether the final response of a mass vaccination programme was as safe and effective as was claimed. We are rightly proud in this country of the effectiveness, speed and operation of the vaccine production and roll-out. It was a triumph of effective collaboration between Government and th Learn more about your ad choices. Visit megaphone.fm/adchoices

  40. 285

    John and Neil

    Original link to GB News live, Thanks to Neli Oliver as always. https://www.youtube.com/watch?v=8WX6YL9JnLw Learn more about your ad choices. Visit megaphone.fm/adchoices

  41. 284

    Plausable mechanism for infertiliy after vaccines

    Rates of successful conceptions according to COVID-19 vaccination status: Data from the Czech Republic https://journals.sagepub.com/doi/10.1177/09246479251353384 Vibeke and team, crowd funding, Me again - here is link to our crowdfunding - it would be great if you would link. https://buymeacoffee.com/batchdependency Observed Adverse effects of COVID-19 vaccination on human menstrual cycle characteristics Limited data, relationship, COVID-19 vaccination status and birth rates. Objectives Nationwide data from the Czech Republic Rates of successful conceptions (SCs) (conceptions leading to live births 9 months later) For women who were either vaccinated or unvaccinated against COVID-19 before SC. Summary monthly COVID-19 vaccination and birth data Women in the Czech Republic aged 18–39 January 2021 to December 2023. Results 1,300,000 women aged 18–39 years in the Czech Republic Proportion of COVID-19-vaccinated women increased from January 2021 until reaching a steady state of around 70% by the end of 2021. At least from June 2021, SCs per 1000 women were considerably lower for women who were vaccinated, compared to those that were unvaccinated, before SC. SC rates for the vaccinated group were much lower than expected based on their proportion of the total population. Conclusions SC rates were substantially lower for women vaccinated against COVID-19 before SC than for those who were not vaccinated. These hypothesis-generating and preliminary results call for further studies of the potential influence of COVID-19 vaccination on human fecundability and fertility. Learn more about your ad choices. Visit megaphone.fm/adchoices

  42. 283

    Joint community health project

    Link to original video https://www.youtube.com/watch?v=skXy3mNqveg Link to Wefwafwa’s channel https://www.youtube.com/channel/UCzsLklGgOttU3Se-WGLp7ow Wefwafwa’s e mail [email protected] Wefwafwa via what's app + 256 756 320736 Everyone on this video gave their permission (together with parental permission where appropriate) to appear on this video. Learn more about your ad choices. Visit megaphone.fm/adchoices

  43. 282

    The 4 lighthouse manifestos

    Check this out, https://lighthousedeclaration.org/declaration/ Ros Nealon-Cook, a psychologist from Australia, had her license suspended for sounding the alarm about the harms to children from government pandemic policy. Ros has joined forces with a number health professionals from around the world who were similarly censored and silenced. Together, they have created The Cape Byron Lighthouse Declaration to raise awareness about the widespread propaganda and censorship of expert scientific opinion. You can read and sign the declaration here: www.lighthousedeclaration.world – adding your signature will take less than a minute. In the coming months, the Lighthouse Declaration team will host a series of webinars and roundtables to further expand the conversation on these critical issues. Ros and the Lighthouse Declaration team, can be contacted through their social media channels or via the website: Twitter: @Lighthouse_Dec Twitter: @rosalina_nc Facebook: LighthouseDeclaration Instagram: @lighthouse_dec Learn more about your ad choices. Visit megaphone.fm/adchoices

  44. 281

    Long covid and long vaccine

    Professor Robert Clancy has found similarities between long covid and long post covid vaccination syndrome. Here he shares new findings on the theory and practical medical management of these two conditions. Thank you, Professor, as always for sharing your time and expertise. Learn more about your ad choices. Visit megaphone.fm/adchoices

  45. 280

    Inconsistencies in official numbers

    Is UK government data accurate? Or is there under-reporting? https://coronavirus.data.gov.uk https://covid.joinzoe.com/data#levels-over-time https://www.youtube.com/watch?v=Hc7A1bVuSJU https://covid.joinzoe.com/post/worryingly-close-to-100-000-new-cases-a-day Poor lateral flow test reporting Less than 50% have government ‘classical symptoms’ Therefore, government under testing Loss of smell and taste, 6 Fever, 8 ONS https://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19/latestinsights Overall, coronavirus (COVID-19) infections continued to increase in England in the most recent week Percentage testing positive still highest in those in school years 7 to 11 Overall prevalence increases up to W/E 23rd October 2.02% in England (1 in 50 people) Week before, 1.79% (1 in 55 people) 2.56% in Wales (1 in 40 people) Week before, 2.31% (1 in 45 people) 1.31% in Northern Ireland (1 in 75 people) Week before, 0.76% (1 in 130 people) 1.36% in Scotland (1 in 75 people) Week before, 1.14% (1 in 90 people) Coronavirus antibodies remain high among UK adults (W/E 3rd October) https://blog.ons.gov.uk/2021/04/28/antibodies-and-immunity-how-do-they-relate-to-one-another/ 92.2% in England 90.0% in Wales 90.8% in Northern Ireland 91.3% in Scotland Positivity has increased in younger adults Showing signs of a slow decline in older adults Antibody finger prick tests A negative antibody test does not mean that a person is not protected Building up to 150,000 UK antibody tests per month Every month for the next year Coronavirus (COVID-19) deaths Between 13 March 2020 and 1 October 2021, 119,869 excess deaths above the five-year average Government figures https://coronavirus.data.gov.uk/details/deaths 140,392 163,515 Current UK deaths (ONS) 12,845 per week 14.8% above average Learn more about your ad choices. Visit megaphone.fm/adchoices

  46. 279

    A threatening phone call

    ‘a threatening phone call’ https://www.telegraph.co.uk/news/2023/11/08/how-astrazeneca-vaccine-was-shelved/ 8th November 2023 In March 2021, The Telegraph was one of the first newspapers to imply a causal link between the jab and blood clots after Norwegian scientists suggested a possible mechanism. On the day we published the story we received a threatening phone call from a senior official at the MHRA warning that The Telegraph would be banned from future briefings and press notices if we did not soften the news. https://www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency From FDA to MHRA: are drug regulators for hire? https://www.bmj.com/content/377/bmj.o1538 June 2022 Industry money saturates the globe’s leading regulators. The BMJ found that the majority of regulators’ budget—particularly the portion focused on drugs—is derived from industry fees Another well-known Cambridge academic got in touch to complain about our “disgraceful fear-mongering headline” on the story, claiming that it would discourage vaccine uptake and cost lives. We politely pointed out that hiding the facts from people was not helpful and could also cost lives. The academic did not respond. In February this year, TikTok removed an audio clip in which I discussed whether the benefit of vaccination was worth the risks for young people, claiming it had breached community guidelines. After we showed that the Government’s own website acknowledges the link, the clip was reinstated. All of this shows a troubling paternalism in government, academia and some media outlets who believe that the public is not capable of weighing up the pros and cons of medical interventions and so must be shielded from the truth. Learn more about your ad choices. Visit megaphone.fm/adchoices

  47. 278

    Midazolam mortality

    Excess Deaths in the United Kingdom: Midazolam and Euthanasia in the COVID-19 Pandemic https://www.researchgate.net/publication/377266988_Excess_Deaths_in_the_United_Kingdom_Midazolam_and_Euthanasia_in_the_COVID-19_Pandemic Citation: Wilson Sy (2024) Excess Deaths in the United Kingdom: Midazolam and Euthanasia in the COVID-19 Pandemic. Medical & Clinical Research, 9(2), 01-21. Macro-data during the COVID-19 pandemic in the United Kingdom (UK) are shown to have significant data anomalies and inconsistencies with existing explanations. England 2020 UK spike in deaths, wrongly attributed to COVID-19 in April 2020, was not due to SARS-CoV-2 virus, which was largely absent, but was due to the widespread use of Midazolam injections, which were statistically very highly correlated (coefficient over 90 percent) with excess deaths in all regions of England during 2020. Importantly Excess deaths remained elevated following mass vaccination in 2021, but were statistically uncorrelated to COVID injections, while remaining significantly correlated to Midazolam injections. The widespread and persistent use of Midazolam in UK suggests a possible policy of systemic euthanasia. Unlike Australia, where assessing the statistical impact of COVID injections on excess deaths is relatively straightforward, UK excess deaths were closely associated with the use of Midazolam and other medical intervention. The UK iatrogenic pandemic Caused by euthanasia deaths from Midazolam and also, likely caused by COVID injections, https://www.researchgate.net/publication/374261986_Early_Indication_of_Long-Term_Impact_of_COVID_Injections but their relative impacts are difficult to measure from the data, due to causal proximity of euthanasia. Global investigations of COVID-19 epidemiology, based only on the relative impacts of COVID disease and vaccination, may be inaccurate, due to the neglect of significant confounding factors in some countries. Learn more about your ad choices. Visit megaphone.fm/adchoices

  48. 277

    Accelerated arterial dysfunction

    Professor Sherif Sultan, MB BCh MCh MD FRCSI DEVS FISVS FASA DMD FRCS/Vasc EBQS/Vasc FAARM FACS FEVBS PhD Professor of Vascular & Endovascular Surgery National University of Ireland Chief of Vascular & Endovascular Surgery at The Galway Clinic Chairman of Western Vascular Institute President of International Society for Vascular Surgery University Hospital Galway NUIG & The Galway Clinic https://acrobat.adobe.com/id/urn:aaid:sc:EU:ea3bf115-1a02-4440-a153-6ec0149f258a https://acrobat.adobe.com/id/urn:aaid:sc:EU:95fadfe1-88d4-4708-8729-ef38596cdcee https://acrobat.adobe.com/id/urn:aaid:sc:EU:a4572ad8-0375-4aa7-a6a7-b9ad0a8d78ca https://acrobat.adobe.com/id/urn:aaid:sc:EU:8a9f87d0-e9a3-4af5-9675-d9dfe4f91e28 https://acrobat.adobe.com/id/urn:aaid:sc:EU:779ab225-f4bf-4757-a540-62e7036c3fef https://acrobat.adobe.com/id/urn:aaid:sc:EU:893d701f-acd0-4f03-bba3-1a8e0ca8fc2e Learn more about your ad choices. Visit megaphone.fm/adchoices

  49. 276

    New disease

    Thank you to Mr. John O’Looney of Milton Keynes Family Funeral Services, https://www.mkffs.co.uk/ Learn more about your ad choices. Visit megaphone.fm/adchoices

  50. 275

    Lab leaks

    Accidentally on purpose https://dictionary.cambridge.org/dictionary/english/accidentally-on-purpose WEF prepares for Disease X https://www.weforum.org/events/world-economic-forum-annual-meeting-2024/sessions/preparing-for-a-disease-x/?utm_source=substack&utm_medium=email Laboratory-acquired infections and pathogen escapes worldwide between 2000 and 2021 https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00319-1/fulltext Laboratory-acquired infections (LAIs), and accidental pathogen escape from laboratory settings (APELS), are major concerns for the community. A risk-based approach for pathogen research management, within a standard biosafety management framework is recommended, but is challenging. due to reasons such as inconsistency, in risk tolerance and perception. Here, we performed a scoping review, using publicly available, peer-reviewed journal and media reports, of LAIs and instances of APELS between 2000 and 2021. Laboratory-acquired infections (LAIs) 309 individuals, 94 reports for 51 pathogens. Eight fatalities 2·6% of all LAIs Neisseria meningitidis (n=3, 37·5%) Yersinia pestis (n=2, 25%) Salmonella enterica serotype Typhimurium (n=1, 12·5%) Ebola virus (n=1, 12·5%) Bovine spongiform encephalopathy (n=1, 12·5%) Accidental pathogen escape from laboratory settings (APELS) 16 APELS were reported Bacillus anthracis (anthrax) SARS-CoV Poliovirus Brucella spp (brucellosis zoonosis) Foot and mouth disease virus Influenza virus H5N1 Examples the discovery of historical variola virus ampoules in cold storage during a move of laboratories at the National Institutes of Health campus in Bethesda, MD, USA in July, 2014 the shipment of live anthrax cultures from US Department of Defense laboratories following incomplete inactivation Lethal Infection of Human ACE2-Transgenic Mice Caused by SARS-CoV-2- related Pangolin Coronavirus GX_P2V(short_3UTR) https://www.biorxiv.org/content/10.1101/2024.01.03.574008v1.full.pdf SARS-CoV-2-related pangolin coronavirus GX_P2V can cause 100% mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain infection. This underscores a spillover risk of GX_P2V into humans https://www.biblegateway.com Then another horse came out, a fiery red one. Its rider was given power to take peace from the earth and to make people kill each other. To him was given a large sword. (Revelation chapter 6, v 4) Learn more about your ad choices. Visit megaphone.fm/adchoices

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ABOUT THIS SHOW

Hello Everyone,My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development of open learning resources for nurses nationally and internationally. LinkedIn profile, https://www.linkedin.com/in/dr-john-campbell-5256223b/Twitter, https://twitter.com/JohnincarlisleDisclaimer; These media including videos, book, e book, articles, podcasts are not peer-reviewed. They should never replace individual clinical judgement from your own health care provider. No media-based material on this channel is suitable for using as professional medical advice. All comments are also for educational purposed only and must never replace advice from your own health car

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Hello Everyone,My name is John Campbell and I am a retired Nurse Teacher and former clinical nurse based in England. I also do some teaching in Asia and Africa when time permits. These videos are to help students to learn the background to all forms of health care. My PhD focused on the development...

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