Druggist For The People

PODCAST · health

Druggist For The People

Four score and seven minutes ago (about an hour and a half) your physician brought forth, upon her desk, a new prescription, conceived in best medical practice, and dedicated to the proposition that all generics are created equal. Now we are engaged in a great civilian war, testing whether that medication, or any medication so conceived, and so dedicated, can help us long endure. And maybe we can feel good at the same time. For forty years as a pharmacist, I've been building bridges - from the doctor to those in need of important drug information - you. With respect for the listener, and from the perspective that it is better to apply a recommended course of therapy than it is to comply with an ordered course, the goal here is not to provide specific answers about your drug therapy, but rather to help you generate the questions that will that will empower you in this. Toward that end, there will be weekly podcasts, very often with guests who will be "the people".

  1. 90

    Laughter: don’t take it too seriously.

    Send us Fan MailSummary:  Laughter:  don’t take it too seriously. Topics:·       Benefits of Laughter 02:00·       Ranting & Raving 06:00·       Leaf Blowers 07:45·       AI Recommendations 08:45·       Meditation – Mindfulness-Laughter 10:10        (Changing Your Chemistry)·       Short-term Benefits = stimulate heart, lungs & muscles 11:00-              Increase endorphins-              Relieve stress·       Long-term Benefits = improve immune system 11:30-              Decrease anxiety·       Negative Effects of Laughter 12:00·       Connect 14:00·       A Bag of Chemicals 14:30·       A Survival Tool 15:30·       “Don’t take it too seriously.” 17:30  Questions and comments to  [email protected]

  2. 89

    Botox – Brought to You by the bacteria Clostridium botulinum

    Send us Fan MailSummary:  This episode is about taking a toxin, isolating it, purifying it and then injecting it into your face; or other parts of your body.  Safe use of botulism toxin A relies upon its local activity.  The indications include cosmetic smoothing, excessive sweating, eye disorders, chronic migraines, and overactive bladder.  Assessing the Benefit-Risk of Botox is also discussed, along with the need for close monitoring.Topics:·       Botulism Toxin A 01:30·       Premarin 02:15·       Exotoxin & Endotoxin 03:00·       Biological Warfare 03:30·       Indications-              Cosmetic-              Severe Sweating-              Cervical Dystonia-              Blepharospasm-              Strabismus-              Chronic Migraine-              Overactive Bladder·       History of Botox 05:50·       Mechanism of Action 06:20·       Benefit-Risk 08:30·       Local Effect 10:30·       Side Effect Rare 13:00·       Iatrogenic Bolulism·       Monitor – Journal 13:30Questions and comments to  [email protected]

  3. 88

    JOURNAVX – A Non-Opioid for Acute Severe Pain

    Send us Fan MailSummary:  Journavx was born of the search for an option to opioids for moderate to severe pain relief.  The early results are mixed, some claiming it to be a miracle drug, others dismayed with its lack of effectiveness and its side effects.  Since Journavx utilizes a novel (non-opioid) approach to severe pain relief, the drug was fast-tracked by the FDA, which is a process used to facilitate the development and expedite the review of drugs which provide unmet medical needs, and thereby provide faster access for patients.  Post marketing review is essential to fully defining this drug’s benefits and risks.  Topics: ·       Opioid Crisis  01:00·       JOURNAVX – Moderate to Severe Acute Pain 01:30·        Mechanism of Action – New!  02:00·       FDA Fast Track – Novel Approach 03:30·       Acute Pain = 14 Dayn Approval 05:00·       Side Effects:  Nausea, Constipation, Headache        Dizziness, Itching, Muscle Spasm. 05:30·       Further Studies Needed…07:00·       Precautions:  Liver Function and Drug Interactions 08:00·       Dosing. 09:00·       New Approach  Post Marketing Monitoring 11:00·       Shared Anecdotal Reports 11:30·       MedWatch – FDA 12:15·       Journaling 14:00·       Cause & Effect 14:30·       Follow-Up! 15:00Questions and comments to  [email protected]

  4. 87

    Panic Attacks, Psychotherapy and Meds

    Send us Fan Mail Summary:  Panic attacks are real and more common than you might think.  This is a discussion of the possible causes of panic attacks and when a panic attack becomes part of a panic disorder.  Psychotherapy and medications, both first-line treatments, are considered here.  The importance of compassion is essential:  be kind to yourself and others.    Topics:·       Panic Attack Symptoms 02:15·       Panic Disorder 04:15·       Rule Out Medical Issues and Toxicities·       Incidence 07:30·       Causes?  09:00·       Compassion 10:15·       Psychotherapy 13:30·       Medications-              Benzodiazepines – Xanax-              SSRI = Zoloft/Paxil/Prozac-              SNRI = Effexor-              TCA = Imipramine-              Beta-Blockers = Propranolol·       Monitor Treatments (Journal) – be patient 18:00·       Be Kind to Yourself and Others 18:50·       988 Questions and comments to  [email protected]

  5. 86

    Why GLP For Me?

    Send us Fan MailSummary:  This podcase provides a review of GLP-1 medications, from describing what they are, how and where the work in the body, and emerging new uses for this class of drug.  The potential benefits of the GLP-1 drugs, coupled with their high cost, have spawned the compounding of these meds, raising legal and safety questions about this process.  Even with the excitement of what these meds might provide, working with your physician and your healthcare team to ensure the safety and efficacy of the medications, and monitoring your treatment, is essential. Topics:  Shared decision-making 01:00Incretin Mimetics 01:40Byetta 2005 03:00Side Effects Become Indications 04:00                  GLP = Weight Loss                  Minoxidil = Hair Growth                  Valproate = Mania tx                  Sildenafil = EDGLP-1 Kinetics 07:15Hormones 09:30Microdosing 12;00GLP-1 Receptors 17:00Exploring other GLP-1 Indications 18:15GLP Anti-inflammatory Effects 23:30More Research Needed to Provide Definitive Answers 24:00                  NAFLD/Parkinsons/Alzheimers/Osteoarthritis/Chemical DependencyMaintenance Med?  28:00Monitor & Work with Healthcare Tea 28:00  Questions and comments to  [email protected]

  6. 85

    Isolation, Loneliness and Medications

    Send us Fan MailSummary:  An epidemic of Isolation and Loneliness?  Recent studies have found this to be true, and the subsequent effects upon the mental and physical health of the isolated & lonely person are significant.  They include an increased risk of dementia, heart disease, stroke, diabetes type II, obesity, depression and anxiety and the risks of the medications used to treat these ailments.  These are potential physical and mental challenges for the person, in addition to the painful experience of isolation, wherein there is a lack of contact and support from others, and loneliness, wherein there is the subjective feeling of not having close meaningful relationships or a sense of belonging.  We’ve all been there.  The idea here is to think about helping yourself - and others - to connect Topics:·       Surgeon General 2023 Epidemic of Isolation & Loneliness 02:00·       Isolation & Loneliness Defined·       Incidence of Loneliness by age 05:15·       “Say Hello in There” 06:10·       Existential Loneliness 09:00·       Health Risks of Isolation & Loneliness 11:00        Heart Disease 29%        Strokes 32%        Dementia 50%         Also increase incidence of Depression & Anxiety, Obesity, Diabetes Type II·       Risks & Causes of Isolation & Loneliness 14:00·       Technology (AI) 16:45·       Additional Meds d/t possible health risks of Loneliness/Isolation 22:45·       Drug for Loneliness?  23:15·       988 Suicide and Crisis Lifeline 25:00·       Talk with Your MD 27:00·       If you are feeling alone, you are not alone in thisQuestions and comments to  [email protected]

  7. 84

    Supplements - Is This Stuff Actually Working?

    Send us Fan MailSummary:  There are a lot of options in the supplements aisle, because there’s a lot of money in it.  Supplements might contain vitamins, minerals, herbs, botanicals, amino acids (part of protein), enzymes and probiotics, as well as binding agents, preservatives, flavoring agents etc.  The label claims for ingredients are required by the FDA to be “truthful and not misleading.”  If a supplement label “supports” or “promotes” proper nerve function, or cellular energy, or metabolism, the claim is so nebulous or general that it might be impossible to prove that it was untruthful or misleading.  What to do? We try to figure that out in this episode. Topics:·       Supplements and $$$ 01:30·       FDA Approved Indication – Not 02:00·       Disclaimer 05:00·       80,000 Supplements 08:30·       Claims:  Health; Structure-Function; Nutrient 09:30·       Beware – Research – Communicate w/ Healthcare Team –  Monitor         & Follow-up  12:00      *    FDA – Reports Problems/Benefits      *    Independent Labs = USP, Consumer Labs 22:00      *    Utilize and work with Healthcare Team. 23:00   Questions and comments to  [email protected]

  8. 83

    Low Dose Naltrexone (LDN)

    Send us Fan MailSummary:  The off-label use of naltrexone for chronic pain and inflammatory conditions is built upon observing patients being weaned from high dose naltrexone for alcohol abuse disorder, as well as its experimental use in boosting the immune system of HIV patients in the 1980s.  Though the long-term use of LDN for chronic pain and the other inflammatory conditions has not been established, this unique mechanism of action may, in the future, provide another proven option for those in need.   Or will it?  We are in the process of discovery.Topics:·       Low Dose Naltrexone Potential Uses 02:00·       Opioid Antagonists Naloxone and Naltrexone·       Receptor Interactions: Affinity/Intrinsic Activity/Dissociation. 04:15·       Naloxone & Naltrexone Chemistry·       Antabuse 08:20·       Fooling the Body – Negative Feeback Loop 11:30·       Microglial Cells Inhibition & Anti-inflammatory actions 12:50·       Applied Science of Medicine 14:00·       LDL Risks·       Quality of Life and Risk-Benefit 17:45Questions and comments to  [email protected]

  9. 82

    Kennedy Bias Killed the mRNA Vaccines

    Send us Fan MailSummary:  Rooting for your favorite team may very well influence your opinion of the referees in the game.  Leave bias there.  In healthcare, double-blind placebo-controlled trials and the metanalysis of studies are attempts to remove bias, so that objective reasoning can rule the day.  JFK Jr. exhibited significant bias about vaccines prior to his confirmation as Secretary of Health and Human Services, and it has been evinced in his decision to stop the funding for mRNA vaccines.   Blatant lies and unchecked bias threaten not only our healthcare options, but the very world in which they operate.  Topics:·      Bias 01:00·      Double Blind Placebo Controlled Studies 01:30·      RFK Jr 02:20·      Science is a Process 04:30·      mRNA 05:30·      Mutations 06:20·      Bacteria Too 07:45·      More Bias 10:00·      You Are The Experiment 12:00·      mRNA Risk Benefit 14:15Questions and comments to  [email protected]

  10. 81

    Tulsi Gabbard, Hillary Clinton & Psycho-Emotional Problems

    Send us Fan MailSummary:  Slinging ugly, triggering words – like “psycho-emotional problems” - is an effort to awaken stigmas in the public against a person.  Reject it.  Mental Health, like our physical health, is an ever-changing dynamic.  Though we expect mental and emotional health and stability in our leaders, the assessment of that issue should be objective and based on the best medical practice, and not on some sloppy reference intended to fan the flames of hate.Topics:·       Psycho-Emotional Problems 01:00·       Unconrtrolled Fits 03:30·       Heavy Tranquilizers 04:30·       Stigma of Mental Health Challenges 05:00·       Public & Self Stigmas 07:00·       Intermittent Explosive Disorder (“Fits of Anger & Aggression”???) 09:30·       DSM-5·       Gelastic Seizures (“Fits of Cheerfulness”???) 10:40Questions and comments to  [email protected]

  11. 80

    Vaccines Tricking Your Immune System - the Benefits and Risks

    Send us Fan MailSummary:  This episode attempts to clarify how vaccines are made, how they are intended to interact with the immune system, and how important it is to obtain an unbiased source of information about the risks and benefits of a vaccine.  Utilize your healthcare team. Topics:·       Polio Vaccines 01:00·       Risk-Benefit 02:00·       Vaccines-Autism 03:00·       Modern Medicine 04:15·       Autism – DSM 06:00·       Immune System (learning what is you) 08:00·       Innate & Acquiered Immunity 11:00·       Chicken Pox Exposure and Shingrix 13:30·       Types of Vaccines 14:45·       Live Attenuated Vaccines 15:30·       Inactivated Vaccines 16:30·       Subunit Vaccines 17:30·       Toxoid Vaccines (Tetanus) 18:15·       Viral Vector·       mRNA 19:10·       BIAS – Remove it 23:30·       CDC Vaccine Risk – Benefit Site 24:50 Questions and comments to  [email protected]

  12. 79

    MAHAhaha

    Send us Fan Mail Summary:  When the president of the United States told his candidate for Secretary of  Health and Human Services to “go wild” on health, food and medicines, I’ll bet he went and celebrated his pick with a McDonald’s cheeseburger and a Diet Coke.  This podcast discusses the danger of placing politics and ideology into the healthcare system, the participants of which currently embrace the practice of Evidence-based medicine.  This is the practice wherein the best available science is combined with the healthcare professional's clinical experience and the patient's values to arrive at the best medical decision for the patient.  The idea is to eliminate bias.  Let’s not go wild on that, in any part of the healthcare system.Topics: ·      What is “Again”? 01:00·      “Go wild” on health, food and medicines? 02:30·      Bias 03:20·      Exercise and Diet 06:15·      RFK Jr Confirmation Hearing 07:00-              Nicotine Pouch?-              Suggest SSRI’s as or more addictive than heroin·      Depedence Vs. Addiction 14:10·      RFK Jr. Actions as HHS Secretary 17:00-              April 11: cause of autism will be found be September·      Possible causes of autism 19:30·      RFK Jr. Actions as HHS Secretary -              May 27: Change COVID Vaccine Recommendations-              June 9: Remove Advisory Committee for Immunization Practices (ACIP) Members·      Evidence Based Medicine 24:30·      Levels of Scientific Evidence (not all are the same) 26:00·      JFK Jr. Swimming in Contaminated Stream 28:30·      No One Should Go Wild on HHSQuestions and comments to  [email protected]

  13. 78

    Nicotine for Weight Loss, Energy, Long COVID, & Autoimmune Disease?

    Send us Fan MailSummary:  I received a question about the possible therapeutic pharmacologic benefits of Nicotine, specifically the idea of cutting the Nicotine Patch for help with energy, autoimmune issues, and weight loss.  Answering this question lead into a discussion of new drugs that may emerge from anecdotal evidence.  In this case, how certain elements of Nicotine’s activity might lead to the development of new drugs with neuroprotective and anti-inflammatory effects, without the risks associated with Nicotine use. Topics:  ·      Nicotine History 01:20·      Nicotine Patches, Side Effects 03:00·      Muscarinic & Nicotinic Receptors 06:00·      Alzheimers and Parkinson’s Disease in Smokers 08:00·      Reasoning Toward Possible Uses 09:00·      CNS & Immune Effects 09:45·       Rheumatoid Arthritis, Gout, Irritable Bowel Disease/ MS - reduce inflammation   11:00·      Journavx 11:30·      Long COVID 12:30·      Big Pharma Skepticism 15:00·      Consider the Source 15:50·      Use Your Pharmacist 17:20·      For All Drugs:  Potential Benefit/Possible Risks  Decide  Positive Attitude  MONITOR  Questions and comments to  [email protected]

  14. 77

    Constipation - The OTC Options

    Send us Fan MailSummary:  Not all laxatives are created the same.  Discussed in this episode are the nonpharmacologic options to relieve constipation, and the OTC Laxative options available should nonpharmacologic efforts fail.  Included is a brief explanation of the peristaltic movement that is pooping, and how the different laxative options affect that process.  Though there is often a silly poop joke or phrase lurking nearby i.e. dropping the kids off at the pool, a healthy and properly functioning bowel is essential for your overall health.  Please consult your healthcare providers for any questions and guidance about constipation and your gut health.Topics:·       Constipation Definition 02:00·       Before Using Laxatives 03:00·       OTC Laxatives 04:00·       Bulk Laxatives (Metamucil/Citrucel/Fibercon) 06:15·       Peristalsis and Bowel Movements 06:45·       Osmotic Laxatives (Miralax/MOM) 07:50·       Stool Softeners (Docusate) 09:30·       Lubricant Laxatives 10:00·       Stimulant Laxatives (Bisacodyl & Senna) 11:00·       Laxative Overuse 12:00·       Rx Laxatives      Irritable Bowel Syndrome with Constipation – Linzess 12:30      Opiate Use – Relistor to prevent GI effects of opiates 13:10·       Onset of Action 14:30-              Bulk = 12 hrs to 3 days-              Stool Softeners = 12 hrs to 3 days-              Stimulant = 6 to12 hrs-              Lubricant =  6 to 12 hrs-              Enema/Suppository = 15 min to 1 hr·       Side Effects/Over usage 17:30·       Interactions with Medication  Consult Pharmacist 19:25Questions and comments to  [email protected]

  15. 76

    Thoughts, Feelings, Food, Drugs and Your Holiday Chemistry

    Send us Fan MailSummary:  The chemistry of your mind and body are almost always changed by the medications you take.  But there is more to it than that.  These changes are changing, in response to both your medications and in response to your thoughts, feelings, food, exercise, and sleep.  About the medications, we focus on the benefit you might receive, and the possible risks associated with a potential drug therapy.  And we keep track of it.  This is always a good idea.  But what about how you think and eat and sleep and move?  Let's talk about it. Topics:·      Pharmacokinetics & Pharmacodynamics 01:30·      Drugs “On board” 02:30·      Drugs & Your Chemistry 03:00·      Cookies & Your Chemistry 04:30·      Exercise, Sleep & Your Chemistry 05:00·      Diet, Thinking, Feeling & Your Chemistry 06:00·      Cortisol & Chronic Stress 06:30·      GABA Receptors (Benzodiazepines) 07:45·      Be nice? 08:40·      Meds & Risk-Benefit 09:00·      Hurricane Helene 09:15·      Premarin (pregnant horse urine) 12:15·      Depression…You Are Not Alone 14:15·      Depression Help Resources 15:15       Suicide & Crisis Lifeline = 988       Crisis Text Line = 741741       Outside of U.S = Befrienders Worldwide·      John Prine “Hello in There” 16:00Questions and comments to  [email protected]

  16. 75

    The Patient is a Person - Removing Healthcare Prejudice (Bias)

    Send us Fan MailSummary:  Preconceived notions within healthcare professionals about what another person might be, before we have a direct, open and genuine interaction with them, can derail the best treatment for that person.  To provide the best treatment, efforts to effectively communicate continue by healthcare; but the person – the patient – must also make efforts to express themselves openly and honestly regarding their healthcare.  Shared decision making:  this episode is about getting in there, establishing an understanding of your options, and working WITH your healthcare team, including your pharmacist!     Topics:  ·      Shared Decision Making 01:15·      Generational Theory 02:00·      Culturally Competent Care 03:40·      Person Type = Another Bias 07:10·      Patient Perspective 12:00·      Medical Terminology = Bias 14:30·      Direct, Open & Genuine Talk with Healthcare 16:30·      Mary Berry 17:15·      LEARN (to facilitate shared decision making) 18:25·      Pharmacists – Team with them!  20:30·      Mayo Clinic 21:00·      Journaling 21:30  Questions and comments to  [email protected]

  17. 74

    An Orange & Red Bloodsucker (with six legs) – Bedbugs!

    Send us Fan Mail Summary:  Why have bedbugs reemerged?  What to do if bitten?  And how to manage and prevent possible bedbug infestation.  Topics:·       Sleep Tight 01:30·       Bedbugs 02:00·       DDT 03:45·       Antihistamine, Topical Steroid Tx 06:15·       DDT & Auto-Immune Disease? 06:45·       DDT Risk Benefit (Africa) 08:15·       Prevention 09:00·       Permethrin 10:15Questions and comments to  [email protected]

  18. 73

    Meds and Good People in a Disaster Zone: Hurricane Helene

    Send us Fan MailSummary:  This episode recounts the experience of Hurricane Helene in North Carolina, from its arrival to the continued recovery.  Being smart about what's fact or fiction, being there for your neighbors, and being prepared for a potential disaster (which we were not) are discussed here.  Also discussed is a possible cure for the stress in this situation...go help someone.  Questions and comments to  [email protected]

  19. 72

    Filling a Prescription – Why Is This Taking So Long?

    Send us Fan Mail Summary:  What’s happening on the other side of the prescription counter?  Probably more than you think.  Safety and appropriateness of the drug regimen is an ongoing process, and it may slow down the speed with which you get your medication, but it’s essential in making sure the drug is safe and efficacious.  The importance of being a good teammate in your own healthcare is what this, and all episodes, is aboutl. Topics:·       Five Safety Checks 02:15·       Clinical Review by Pharmacist 04:00·       Best Treatment Evolving 06:45·       Provide Complete and Accurate Medication Profile 11:15·       Be a Good Teammate on Healthcare Team 12:00·       It’s For You 13:00·       Medication Counseling – Use It 13:254·       Journaling (determine Cause & Effect) 14:30·       Work WITH Your Healthcare Providers 15:00Questions and comments to  [email protected]

  20. 71

    Money, Money, Money…and Medications

    Send us Fan Mail Summary:  Paying $75,000 dollars for a car because you want to have a back massage between home and work is one thing, but to face exorbitant costs because you want to live a healthy and longer life is a tough pill to swallow.  Discussion of the risks and benefits of any medication with your healthcare provider is essential, and the costs of that therapy should be included in that conversation.  Topics:·       Most Common Med Indications 03:30·       Top 10 Most Prescribed Medications 04:00·       Most Common Meds by Cost 05:30·       Pharmacy Benefit Manager (PBM) 10:30·       Managing Cost 12:15·       Pharmacoeconomics 13:00·       Risk-Benefit·       GoodRx 14:00 Questions and comments to  [email protected]

  21. 70

    neffy® nasal spray– emergency epi without a needle

    Send us Fan Mail Summary:  neffy® nasal spray received fast track approval from the FDA on August 9, 2024 for the emergency treatment of type I allergic reactions, including anaphylaxis, in adult and pediatric patients who weight at least 66 pounds.  This may be a gamechanger in that it provides emergency epinephrine treatment for anaphylaxis without needles.  But, as with all medications, correct use and monitoring is necessary.  Topics·       Fast Track Approval 01:30·       $$$                          03:15·        Minimum Weight 66 pounds 04:15·       Approval Process 06:00·       Pharmacokinetics & Pharmacodynamics 07:00·       Epi Mechanism of Action 08:00·       How to use neffy 10:45·       Storage 13:00·       Gamechanger? 15:00·       risk – BENEFIT 16:20·       Dosing (1/2 Life) 18:25·       Storage 22:15Questions and comments to  [email protected]

  22. 69

    Opill Update – It’s Out There Now

    Send us Fan MailSummary:  Previous podcasts (July 2023) have covered The Pill and the newly approved, progestin only, OTC oral contraceptive – the Opill.  The Opill is on the shelves and available online now.  This episode provides a brief overview.  For more detailed information about the Opill, consider listening to the July 2023 podcast:  Opill – the OTC Pill.   Topics:·      Opill-Antibiotics Interaction (Rifampin) 02:00·      How to Take 02:40·      Reminder July 2023 Podcasts:  The Pill and The Opill 03:10·      Missed Doses 04:20·      Opill Drug Interactions 07:15·      Brief History of Oral Contraception 09:00·      Opill Contraindications 12:20   Questions and comments to  [email protected]

  23. 68

    Body and Mind and Being Kind – Another Drug

    Send us Fan MailSummary:  There are more ways to change your chemistry than taking drugs.  Kindness.  Being helpful, generous, and considerate – without expecting anything in return – has positive effects upon both the body and mind.  But here’s the rub:  you must be kind without expecting anything in return.  So don’t be kind to be healthy…simply be kind.  It’s all easier said than done.  This episode also addresses the need for kindness in healthcare, from the healthcare professionals to the patient, and from the patient to the doctors, nurses, pharmacists, therapists – all who are trying to help.  Topics:·       Kindness Definition 01:15·       Body Benefits 01:30·       Mind Benefits 02:00·       Safe & Efficacious 06:00·       Trust 09:30·       Doctor-Patient Relationship 11:00·       Kickstart Kindness (Mayo Clinic) 13:00Questions and comments to  [email protected]

  24. 67

    Chemical Restraints

    Send us Fan MailSummary: Chemical and Physical Restraints are frightening terms, and yet the use of one or the other is sometimes necessary.  This episode discusses the appropriate use of chemical restraints to treat agitation, as well as what may be the inappropriate use of medications to chemically restrain a person.   Topics:·       Agitation 02:00·       Danger to Self/Others 02:30·       AMA 02:50·       Respect the Person 05:45·       Informed Consent 10:15·       Detox (Klonopin/Librium/Ativan/Valium)  10:45·       Risperdal/Seroquel/Xyprexa 11:15·       Nonpharmacologic Interventions 12:30·       Rexulti 16:30·       Participate 18:45Questions and comments to  [email protected]

  25. 66

    The Prescription Cascade

    Send us Fan MailSummary:  To get the maximum benefit and minimize the risks of your meds, stay involved.  Monitor, journal and communicate with your healthcare team to make sure your meds include only those that you actually need.  Avoid the Prescription Cascade.Topics:* Polypharmacy 01:15* Prescription Cascade 0410*Therapeutic Duplication 06:00* Monitor, Journal & Communicate 07:15* Cause & Effect 07:50* Communicate Changes Between MD's 10:00* Max Benefit & Minimize Risk 11:30* Use Your Pharmacist 11:45Questions and comments to  [email protected]

  26. 65

    Pill Dysphagia, Sister Hildegard and Candy...It Can Be a Hard Pill to Swallow

    Send us Fan MailSummary:  If it’s a hard pill to swallow, you’re not alone.  In this episode we discuss why not to crush or break certain medications and possible techniques to help in overcoming pill dysphagia.  As usual, consult your pharmacist. Topics:·       Pill Dysphagia Definition 02:30·       Prevalence 04:30·       What Not to Crush and Why 05:40·       Drug Formulation Abbreviations 09:30·       Narrow Therapeutic Window 11:15·       Toprol XL, Sinemet CR – Exceptions 12:30·       Pill Dysphagia Techniques 13:00·       Applesauce 14:00·       Mayo Clinic 19:30 Questions and comments to  [email protected]

  27. 64

    Sunscreens, Sun blockers, Chemical Sunscreens and Physical Sunscreens–What's Up With That?

    Send us Fan MailSummary:  SPF and Broad Spectrum Protection From UV Rays – A more detailed discussion of protecting your skin from the damaging effects of UVA and UVB radiation.Topics·       Chemical &Physical Sunscreens 02:00·       UVB & UBA 03:00·       Skin Types 04:00·       Ozone 05:00·       EPA – Atmosphere Warnings 05:20·       Broad Spectrum Protection 07:45·       Physical = Blocker; Chemical = Absorber 09:30·       UV Radiation and Vitamin D 10:40·       Photosensitivity by Drugs 11:50·       Apply Liberally & Often 13:25·       Sprays 14:00·       Babys and Children 17:00·       Sensitive Skin = Physical 18:00·       Chemical Sunscreen Absorption? 18:30·       Bug Repellant & Sunscreen? 19:15Questions and comments to  [email protected]

  28. 63

    SPF & Broad Spectrum Protection - Understanding Sunscreens - A Brief Discussion

    Send us Fan MailSummary: Just a little reminder about the negative (and positive) effects of Ultraviolet Radiation (both A & B), the options for managing those negative effects, and the drugs that may cause photosensitivity. Topics:·       Out of Sight, Out of Mind 01:00·       UV Protection 01:30·       UBV & UVA Radiation 02:00·       Chemical Sunscreens 02:40·       Physical Sunscreens 03:20·       Broad Spectrum Protection 04:00·       Apply Liberally & Often 04:40·       Children 05:30·       UV Radiation, Cholesterol & Vitamin D 06:30·       Photosensitivity Drugs 07:30·       Nothing on Skin but Shade? 08:00Questions and comments to  [email protected]

  29. 62

    Is My Generic Drug Actually Equivalent?

    Send us Fan MailSummary:  This episode discusses what makes a generic drug equivalent to a brand name drug, according to the FDA, and why some variability is okay - and unavoidable.    Also discussed is the importance of monitoring your response to the generic medication, use of Pill Identifiers, participating in the FDA Medwatch program, and utilizing your pharmacist for questions about generic substitutes, including the excipients that may be different from one manufacturer to another. Topics:·       Changing Generic Companies 02:30 ·       Sertraline (Zoloft) 04:00·       Drug & Quantity Same 04:30·       Excipients Different 05:10·       Bioequivalence 05:30·       Pharmacokinetics 06:00(Rate of absorption, Total Drug absorbed)·       Variance 07:00·       Statistics 08:00·       Confidence Interval 08:30·       Variance and Probability 12:30·       Monitor You! 13:45·       Pill Identifier 14:00·       MedWatch – FDA 14:40·       Excipients 16:00Questions and comments to  [email protected]

  30. 61

    Vraylar – A ‘Lift’ for Treating Major Depression

    Send us Fan MailSummary:  If you’re watching your TV, we’re seeing what you see:  Drug Ads.  In this episode, we take a look at Vraylar as an add-on to your current antidepressant.  So bottom line, what is it, this Vraylar?  Topics:·       To Begin With:  00:45988 is the Suicide and Crisis Hotline, offering 24/7 call, text and chat access to trained crisis counselors who can help people experiencing suicidal, substance use, and/or mental health crisis, or any other kind of emotional distress 1-800-FDA-1088 or visit www.fda.gov/medwatch to report negative side effects of drugs to the FDA·       Commercials 03:00·       “Stuck…Lift” 04:15·       Vraylar Mechanism of Action 04:30·       Second Generation Antipsychotic 05:15·       Indications 06:10·       Add-On to Antidepressant for Major Depression 07:45        (with Prozac/Paxil/Zoloft…Effexor/Cymbalta…Wellbutrin)·       Maximizing Benefits and Managing Risks 09:30·       Monitor & Participate 12:15·       Side Effects & Adverse Drug Reactions 12:30·       Benefits 14:15·       Drug-Drug Interactions 17:15(includes all meds and supplements)·       Utilize Your Pharmacist 19:00·       Journal 20:30·       Right Drug at the Right Dose – for You 21:30 Questions and comments to  [email protected]

  31. 60

    Proton Pump Inhibitors & Dementia

    Send us Fan MailSummary:  The Proton Pump Inhibitors (PPI’s), which include Prilosec, Prevacid, Protonix, Aciphex, and Nexium, are a very effective group of drugs to treat heartburn and reflux, but as with every other drug, there might be side effects and adverse effects, both short and long-term.  In this episode, we discuss the possible link between the long-term use of PPI’s and dementia, as reported in the press and medical journals.    Topics:·       Proton Pump Inhibitors (PPI’s) 01:30·       H2 Blockers (Tagamet, Pepcid) 02:00·       Prevacid, Prilosec, Protonix, Nexium, Aciphex… 03:40·       Cause & Correlation 05:10·       Depression & Dementia (Correlation) 07:20·       How PPI’s Might Cause Dementia (MOA) 08:30·       Neurofibrillary Tangles and Amyloid Plaque 09:00·       Blood-Brain Barrier 09:45·       PPI’s & Decreased Vitamin B12 Absorption 11:00·       Benzo’s & PPI’s (Diazepam & Omeprazole) 12:00·       Participate in Care (Talk With Your Pharmacist) 13:30·       Medication Reconciliation 19:15·       Got a Question – Ask Your Doctor/Pharmacist 20:00·       Conflicting Study Results = We Don’t Know! 20:25·       Risk-Benefit 22:30Questions and comments to  [email protected]

  32. 59

    Poison Ivy - Facts, Fiction & Remedies (OTC & Rx)

    Send us Fan MailSummary:  If you have poison ivy, can you spread it to someone else?  If the poison ivy is dead, can you still have a reaction if you touch it?  Where else can you get poison ivy, besides touching the plant?  This episode addresses these questions, and in so doing, touches on the prevention and treatment of the contact dermatitis caused by poison ivy, poison oak, and poison sumac. Topics:·       Urushiol Oil 01:50·       Contact Dermatitis 02:15·       Spread? 02:55·       Dogs/Cats/Clothes/Tools 04:30·       Inflammation 06:45·       Prevention 07:45·       Antihistamines 09:25·       Wash Clothes 10:00·       Topical Hydrocortisone 11:25·       Topical Anesthetic 13:25·       MD – Rx Treatment 15:00·       Prednisone Oral 15:25·       ID Poison Ivy, Oak, Sumac 16:15·       Use Your Pharmacist!     Questions and comments to  [email protected]

  33. 58

    Panic Attack Meds: Paxil, Prozac, Effexor XR, Xanax, Klonopin

    Send us Fan Mail Summary:  When the panic attack comes from what’s inside, where do you hide?  It’s thought that a panic attack is physiologically very much like a flight or fright response, comparable to encountering a Grizzly bear on a trail.  In this episode we discuss the current medications available for treating panic attacks and panic disorder and how these medications work.  We also discuss other non-medication options such as psychotherapy (talk therapy), exercise, yoga, and acupuncture.    Options:·       Panic Attack 01:45·       Fight or Flight Response 02:15·       Quality of Life 03:25·       Panic 04:25·       Symptoms 05:00·       Risks for Panic Attacks 06:45·       Complications of Panic Attacks 08:00·       Prevention  08:00·       Treatments·       Prozac/Paxil – SSRI’s 09:30·       Effexor XR – SNRI 09:55·       Risk-Benefit 11:45·       Xanax/Klonopin – Benzo’s 12:45·       Risk-Benefit 14:30·       Journaling 15:00·       Use Your Pharmacist! 15:45·       Non-Med Option – Psychotherapy 16:15·       Cognitive Behavioral Therapy 17:00·       Participate! 17:35·       Carol’s Mom – Help Someone 23:50Questions and comments to  [email protected]

  34. 57

    Blood Thinners – Aspirin to Xarelto

    Send us Fan MailSummary:  Blood clot formation and breakdown happens all the time.  It’s when the body potentially forms clots where they aren’t needed (AFib) that we run into problems:  strokes and heart attacks.  In this episode we make the distinction between antiplatelet drugs and anticoagulants and their roles in preventing unwanted clots.  How they work?  Once again, we’re just tinkering with a natural process in our bodies. Topics:·      Balance of Clot Formation and Breakdown 02:15·      Tissue Plasminogen Factor 02:45·      Blood Thinner = Antiplatelet & Anticoagulant 03:40·      Side Effects = Bleeding 05:30·      Monitor! 08:00·      GI Bleed 11:00 ·      Blood Pressure 12:15·      Journaling 13:00·      Plavix, Brilinta, Effient, Aggrenox 14:40·      Warfarin – Rat Poison? 15:45·      Acute Coronary Syndrome 19:45NSTEMI/STEMI/Unstable Angina·      Reversal of Anticoagulants 22:30·      Direct Oral Anticoagulant (Pradaxa,Xarelto,Eliquis) 24:15·      Duration of Treatment 25:15·      Participate 26:00Questions and comments to  [email protected]

  35. 56

    Xeljanz & Opzelura – What the Flip is a JAK Inhibitor?

    Send us Fan Mail Summary:  The drug ads float images of happy people across the room, with a voiceover discussing the mechanism of actions of the drug (JAK inhibitor) along with an undercurrent of warnings and side effects of the drug.  One of the newer drug groups are these JAK inhibitors, an oral form of targeted immunotherapy.  This episode attempts to explain this drug group, and also discusses to whom exactly the drug companies are directing their ads. Topics:·       Drug Ads 01:20·       Opzelura 02:00·       Targeted Immunotherapy 02:45·       Monoclonal Antibodies (MABs) 03:15·       JAK Inhibitors – small molecules 03:45·       Risk-Benefit Discussion 14:30·       Black Box Warnings 15:30·       Monitor and Journal 19:00·       Participate!  Questions and comments to  [email protected]

  36. 55

    Anticholinergics - Over 600 Meds Cause This Type of Side Effect

    Send us Fan MailSummary:  This episode introduces a phrase uttered thousands of times every day regarding medications:  anticholinergic side effects.  A brief discussion follows about how and why these side effects may occur, what these side effects are, the drugs that may cause them, and the importance of discussing these possible side effects with your pharmacist and physician.  Having a side effect of a medication is not unusual, but it shouldn’t it be unusual for you to understand the benefits of your medication and at the same time manage the side effects, by working with your doctor and pharmacist.    Topics:·       Acetylcholine 01:35·       Central Effects 02:30·       Peripheral Effects 03:00        (muscle and autonomic nervous system)·       Alzheimer’s Treatment 03:45·       Aricept, Exelon, Razadyne 04:00·       Side Effect due to too much acetylcholine = cholinergic 04:30·       Side Effects due to blocked acetylcholine – anticholinergic 05:30·       Peripheral Autonomic Side Effects of anticholinergics 06:30·       Central Side Effects of anticholinergics 07:45·       Beer’s List 08:00·       Side Effect or Symptom? 08:45·       Drugs causing Anticholinergic Side Effects 09:00·       Journal-Communicate 10:20·       When to accept Side Effects, Risk-Benefit 11:30·       Work with your healthcare team 12:00  Questions and comments to  [email protected]

  37. 54

    Rescheduling and Legalizing Marijuana - Understanding the Difference

    Send us Fan MailSummary:  Marijuana is currently considered by the government to have the same abuse and dependency potential as heroin (Schedule 1), and yet 27 states have legalized marijuana either for medicinal and/or recreational use.  This makes no sense.  This episode addresses this disconnect and delves into the issues created by a few U.S. Senators who want to deschedule and legalize marijuana.  Legalizing marijuana may address the changing attitudes toward marijuana and its place in society, but de-scheduling it fails to make a distinction between marijuana’s use as a recreational drug and its use as a medication.  This episode seeks a solution to this issue.     Topics:·       Elizabeth Warren, Stephen Colbert 01:00·       Scheduled Drugs I-V 01:50·       Schedule I Drugs 02:15        No medical use; high abuse/addiction potential        Marijuana, Heroin, LSD, Ecstasy, Peyote…·       Deschedule Marijuana? 03:45·       Alcohol a drug? 04:00·       Prohibition 04:50·       Marijuana a drug?...a medication? 05:45·       Cannabis Sativa = plant 06:20        Cannabinoids = compounds in plant·       Solution? 07:00·       Legalize the plant, Reschedule the compounds 08:00·       Pot Potency 09:00·       Department of Health & Human Services – Schedule III 11:05·       Marijuana Drug Interactions 12:45·       Epidiolex, Marinol, Cesamet 13:40·       Kinetics, Dosage, ADR, Drug Interactions…14:30·       Risk-Benefit 16:00·       Gateway Drug? 16:30·       Plant & Compounds 18:00·       More Potential Medical Uses 18:30·       Ch-Ch-Change  Questions and comments to  [email protected]

  38. 53

    ED - The Ups & Downs of Drugs and Sex

    Send us Fan MailSummary:  The complex dynamics of sexual dysfunction is beyond the scope of this episode, but what we can discuss is the effect that drugs, both prescription and OTC, can have on causing sexual dysfunction (in this podcast, primarily ED in men).  The importance of education and clear communication between a patient and their healthcare team is essential, to determine if the sexual dysfunction may be due to a side effect of a medication or is it a symptom of some other physiologic or psychological cause.  Moving forward, using your physician to address these problems may result in  fine-tuning your current medications, and this may also avoid possible drug-drug interactions with medications to treat ED.     Topics:·       Excitement, plateau, orgasm, resolution 02:00·       Erectile Dysfunction (ED), non-drug causes 03:30·       ED, Drug Causes 05:10·       Side Effect or Symptom (anti-depressants & depression) 05:30·       Anti-depressant Options 06:40        (Bupropion, Remeron, Trintellix, Viibryd)·       Viagra, Cialis 07:30·       Anti-psychotics 08:30·       Mood Stabilizers (Lithium, Carbamazepine) 09:30·       Noncompliance 10:00·       Benzodiazepines 10:40·       OTC Drugs (Benadryl, Pepcid, Zantac…) 11:30·       Journaling-Communicating 11:45·       Blood Pressure Meds 14:15        (diuretics, alpha blockers – Hytrin, Minipress, beta blockers)·       Viagra, Cialis Drug Interactions 16:30·       ED & CHF 17:40·       Priapism 19:20·       Supplements 20:30·       Women & Sexual Dysfunction 21:40·       Addyi 22:30·       Vyleesi 23:00·       Non-drug Options 24:30·       Cause and Effect (figure it out!) 25:00   Questions and comments to  [email protected]

  39. 52

    Insomnia…Symptom or Side Effect?

    Send us Fan MailSummary:  Knowing when a “symptom” is actually a side effect can save you a lot of trouble.  By participating, by providing your physician and pharmacist an accurate accounting of when medications were started - and when possible side effects occurred – any changes to your medications will be based on a more accurate picture. It’s a process.  And it can be complicated, but the accurate and timely sharing of your observations, whether they be signs, symptoms or side effects, is how you can work with your physician to provide the best treatment for you. Topics:·       Side Effects, Symptoms, Signs Definitions 01:30·       Risk-Benefit? 05:30·       CHF & Beta Blockers 07:00·       Confirming Cause & Effect – Statins 08:30·       INSOMNIA 11:00       (primary, secondary, onset, maintenance, mixed)·       INSOMNIA Secondary Causes 12:30·       Worry 15:00       (meditation, cognitive behavioral therapy…)·       Your Pharmacist (research possible SEs) 18:00·       INSOMNIA Primary Causes 19:15      (Depression, anxiety, hyperthyroid, sleep apnea      Restless leg syndrome, Alzheimers…)·       ??? Symptom or Side Effect???  21:00*      JOURNAL.  JOURNAL.  JOURNAL.·        Medwatch FDA 23:00·       Adverse Drug Reaction 23:30Questions and comments to  [email protected]

  40. 51

    Gas Station Heroin (Zaza, Tianna Red, Neptune's Fix) & ED Pills (Rhino)

    Send us Fan MailSummary:  I think people trust that if a product is displayed in nice bright packaging beneath the bright white lights of the gas station, that it must be okay, it must be meeting some king of standard.  Not necessarily.  This episode addresses two types of “gas station drugs”:  gas station heroin and ED pills.  Those pills may well have gotten to those shelves and the FDA had no idea about it.  Since there is a disclaimer stating the FDA has not evaluated any claims and that the product is not intended to treat, cure or prevent any disease, most people think the worst that can happen is nothing.  This episode is about not taking that chance.Topics:·      Gas Station Trust 01:30·      No Doz 02:15·      Dietary Supplement Health Education Act (DSHEA) 1944 03:00·      Supplement Explodes on market 03:30·      FDA does not approve supplements; Reacts to problems 04:00·      Gas Station Heroin 05:00·      Tianeptine 05:30       Zaza/Tianna Red/Neptune’s Fix·      Gas Station Heroin Claims 06:20       (improved brain function/treat anxiety & depression/pain relief…)·      Opioid withdrawal Symptoms 06:45·      Other ingredients? 08:00·      Problem = Products are not reviewed for safety or effectiveness 10:00·      Erectile Dysfunction (ED) Pills 11:00·      Rhino 11:45·      What’s in the pill? 12:50·      Possible Side Effects 14:30·      Board of Pharmacy Notification16:00·      Utilize Pharmacist 17:00·      Reference = Natural Products (Facts & Comparisons) 18:00·      Since FDA doesn’t review, see if your pharmacist can 19:00Questions and comments to  [email protected]

  41. 50

    Big Pharma

    Send us Fan MailSummary:  The big pharmaceutical companies have always had a choice:  whether to place their focus on the patient or on profits.  Every pharmaceutical company (Eli Lilly has determined that they are a “medicine company’) will attempt to present as being there for the people, and they will have a business plan that is about profits and the “health” of the company.  But Big Pharma is not in the clothing or automobile business…they are in the “health of the people” business.  So why develop a drug that – due to its price – may be out of reach for the average patient in need?  Profits for the drug company are expected, but to what extent, and at what cost?   Topics:·      Name it to Hate it 01:30·      Public Distrust in Big Pharma 03:00       ($$$, Concealing Facts about Safety, Patents)·      Research & Development/Rx Sales 04:15·      Humira – a monoclonal antibody 06:40·      New Drug Application & Patent 07:00·      More Patents and More Money 08:20·      Biosimilar Options Prevented 09:00·      Enbrel 09:45·      Meds for the People 10:30·      Bernie Sanders – HELP Committee 11:15·      Drug Advertising 12:15·      Vioxx 13:55·      Purdue Pharma – Oxycontin 14:40·      Free Lunches 16:50·      Big Pharma Lobbyists 18:00·      1800 Lobbyists for 535 Members of Congress 20:00·      Be a Lobbyist for You! 20:30·      In the Meantime – Pharmacoeconomics 21:20·      Monitor – Journal – Communicate 22:45·      Know what we Don’t Know 22:20·      Greed is Real 26:40·      Participate 27:40 Questions and comments to  [email protected]

  42. 49

    Preventing Medication Errors – Part 2

    Send us Fan MailSummary:  The discussion of medication errors continues here, with a focus on the opportunities to prevent medication errors.  Not all prescription medications are created equal.  Regarding medication errors, this means that the potential adverse events that might occur, with an error, are more severe with high-risk medications.  Are you on a high-risk med?  Once again, a person who is familiar with their drugs, and motivated to participate in their own care, with their healthcare team, is essential to medication management, including preventing medication errors.  And finally, a reminder:  you are not on an island. Work with your healthcare team, including your pharmacist.    Topics:·      The 5 Rights of Medication Administration 01:30·      Pill Identifier 02:45·      Risk Factors 09:00·      Patient Education 10:30·      Indication? 11:15·      Intended Outcome? 11:30·      Adverse Events (possible) 11:40·      High Risk Medications 12:30·      Blood Thinners 13:30·      Minimize Distractions 14:45·      Drugs in Drug Errors 16:10      Insulins/Albuterol/Morphine/Potassium Chloride      Heparin/Levofloxacin/Cephalexin/Furosemide     Vancomycin·      Medication Adverse Events in ER Visits 19:00       And Hospitalizations·      Monitor Drugs with High Risk of Toxicity 21:00      (Warfarin, Insulins, Digoxin…)·      Medication Reconciliation 21:30·      Journal and Team Approach 23:10·      “Human Proof”? 23:30Questions and comments to  [email protected]

  43. 48

    Preventing Medication Errors - Part 1

    Send us Fan Mail Summary:  The goal is always to have zero medication errors, and yet they occur.  This episode takes a look at what is considered a medication error (missed doses count), how often medication errors occur, how often they cause harm to the patient (who is actually a person), and the importance of a team-approach (pharmacists, physicians, nurses, patients, and anyone who is part of the person's healthcare)  to preventing medication errors. Topics:·      Medication Errors – Commission & Omission 04:30·      Med Error Prevention:  Team Approach 04:45·      Flexeril Dose 06:45·      Beers Criteria Medication List 07:00·      Medication Errors -> Drug Related Problems 08:00·      ER Visits due to Medication Events (14%) 09:15       (32% of these due to noncompliance)·      Hospital Discharge Meds Knowledge      (28% of patients could list discharge meds;      Fewer could state intended use of medications.·      Journaling 13:15·      Frequency of Medication Use 14:10·      Polypharmacy 15:30·      Medication Error Incidence & Harm 16:50·      Medication Error Incidence of Death 19:00  Questions and comments to  [email protected]

  44. 47

    Why Three Drugs for One Problem?

    Send us Fan MailSummary: To be more involved in your healthcare - your medications in particular - and to be able to participate in a conversation with your pharmacist or doctor, you might need to become your own detective.  And to that end, this episode briefly reviews the different drug classes in order to help you to realize the “whys” of your drug regimen, and in turn to more actively participate in your care, with your healthcare team.  Topics:·      Allergic Reaction – Chemical Class 03:30·      Sulfa and Sulfur – the Difference 04:20·      Therapeutic Class = Indication = What it’s for 05:20·      Same Druggists 06:10·      Mechanism of Action – Digging Deeper 06:50·      Multiple Mechanisms of Action 08:25·      Therapeutic Duplication 10:45·      Only One Chainsaw 11:20·      Controlled Substances 11:45·      Get in the Conversation! 13:15·      Be Your Own Detective 14:00Questions and comments to  [email protected]

  45. 46

    Ingrezza and Austedo for Tardive Dyskinesia

    Send us Fan MailSummary:  The relatively recent release of Ingrezza and Austedo (2017) offer an option for the treatment of the abnormal involuntary movements associated with Huntington’s Disease and Tardive Dyskinesia (TD), a condition associated with the use of neuroleptics.  This episode addresses the multiple activities of dopamine, how neuroleptics work by blocking dopamine receptors, and how this may result in TD.  In turn, the presumed activity of Ingrezza and Austedo are discussed, potentially easing the distressing symptoms of TD.Topics:·      Involutary Movement 01:20·      AIMS 02:00·      Tardive Dyskinesia TD 02:30·      Risk-Benefit 04:00·      Dopamine 04:20·      Dopamine Receptor Blocking Agents (neuroleptics) 06:00·      Risk of TD (Haldol, Prolixin, Reglan…) 07:40·      Ingrezza & Austedo for TD 10:00·      Dopamine & Acetylcholine Balance 11:30·      Dopamine Effects 13:10·      Dopamine Neurotransmitter 15:20·      Ingrezza & Austedo Mechanism of Action 18:00·      TD Symptom Relief 19:00·      Ingrezza & Austedo Dosing, Side Effects, Precautions… 20:00·      Drug-Drug Interactions 27:00 Questions and comments to  [email protected]

  46. 45

    Evidence Based Practice Includes You -- Get in There!

    Send us Fan MailSummary: Any job is made easier – or possible – by having the right tool for the job.  The same goes for getting the most benefit out of your drug(s) and minimizing the risks of your medication.  The right tool for this is at your fingertips…actually, it includes your fingertips:  it’s you, being a drug detective. Topics:·      The Right Tool 01:00·      Get in the Game 01:55·      Evidence Based Medicine 02:25·      Patient Values 03:00·      Utilize Your Pharmacist 03:45·      Drug Detective – Journal 04:35·      Deep Dive 05:50 Questions and comments to  [email protected]

  47. 44

    Trazodone for Insomnia – Off Label Drug Use

    Send us Fan MailSummary: This episode looks at the relatively widespread use of Trazodone for insomnia, an off-label drug use of this antidepressant.  Currently, there is some disagreement in the medical community on Trazodone’s place in the treatment of insomnia, but that does not necessarily make its use wrong or inappropriate.  While that discussion goes on, what can you do about it’s off-label use now?  Listen.     Topics:·      Twenty Rx FDA Approved Meds for Insomnia 02:30·      Trazodone not a DEA Controlled Substance 03:00·      Benzodiazepine Use History 03:30·      1987-1996 Trazodone Use Up, Benzo Use Down 04:00·      Why Trazodone? 05:00·      Evidence Based Medicine 05:30·      Quality of Evidence 06:15·      What Can You Do? 09:30·      Risk-Benefit 11:00·      Drug Journal 11:15·      Participate 11:30    Questions and comments to  [email protected]

  48. 43

    A Prostate Cancer Discussion

    Send us Fan MailSummary:  A listener shares his experience with the treatment of his Prostate Cancer, from the initial diagnosis, research into the best treatment for himself, his strict adherence to this treatment, and his continuing follow-up as he is now seven years cancer-free.  This discussion attempts to clarify some of the terminology encountered in this listener’s journey. Topics:·       Treatment Options 01:50·       Wait and Watch·       Surgery·       Hormone Therapy·       Radiation Therapy·       Immunotherapy·       Do Research – Support Groups 04:00·       Questions When Told You Have Prostate Cancer 05:00·       Signs & Symptoms same as BPH 07:00·       Questions When Deciding on Treatment Plan 08:00·       Biopsy 10:00·       Anti-androgen 11:00·       Radiation (Brachytherapy) 11:20·       Quality of Life 16:50·       Attitude? 17:30·       Gleason Score 18:00·       Talk to People – MD, Support Group 20:00·       Follow-up With MD·       Resource:  American Cancer Society 22:40 Questions and comments to  [email protected]

  49. 42

    Adjusting the Drugs to You: Lisinopril, Losartan, Lithium and Table Salt

    Send us Fan Mail Summary:  Sometimes when you start a medication, you first might have to adjust to the idea of taking a drug every day, and then to the reality of its effects upon your body and mind.  But this episode is about another step that you might want to add to this scene:  monitoring and then communicating with your healthcare provider.  When was the last time your doctor called to see how you were feeling?  It’s you who has to start this communication, and with this interaction, you might just find the drugs being adjusted to you. Topics:·      Shared Decision Making 01:50·      Staying In the Game 02:10·      Supplements and OTC’s 02:45·      Adjusting the Drug to You 03:00·      Dosage? 05:15·      ACE Inhibitors to ARB’s 06:10·      Clarifying Options 06:45·      Clinical Parameters 08:20·      Reporting Side Effects 09:15·      It’s About You 10:10·      Lithium Carbonate & Table Salt 10:40·      Fine Tune Your Drugs to You 12:15  Questions and comments to  [email protected]

  50. 41

    Why Gut Health Matters and How Your Drugs Might Affect It

    Send us Fan MailSummary:  The balance of the flora in the gut is essential to maintaining a healthy barrier between what’s in your GI tract and what’s in your bloodstream.  This episode addresses how broad-spectrum antibiotics can cause C. Diff, the dramatic effects of this and how it is treated.  Also discussed is how diet, alcohol and some drugs may affect the balance and diversity of the microbiome in your, thereby causing Leaky Gut (allowing contents of gut into the body), which in turn may cause or aggravate a variety of conditions, from autoimmune disorders to diabetes to Alzheimer’s.    Topics:·       Gut-Brain Connection 01:30·       Finding the Mother Tree 03:00·       Antibiotics & C. Diff 04:40·       C. Diff Treatment with Drugs 06:15·       C. Diff Treatment with Fecal Transplant 07:50·       Prebiotics 08:45·       Antibiotic Stewardship 09:25·       Leaky Gut 09:50·       Leaky Gut Causes – Diet & Alcohol 15:10·       Leaky Gut Causes – Laxatives, Proton Pump Inhibitors, NSAIDS, Statins? 17:90·       Gut Serotonin Production 21:30·       Journal & Participate 23:30·       Conditions Caused by Leaky Gut 26:00·       Heart Disease? ·       Autoimmune Diseases ·       Alzheimer’s·       Dietician & Nutritionist Resources 30:00·       Diet & Med-Gut Connections – Pay Attention & Participate 32:40    Questions and comments to  [email protected]

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ABOUT THIS SHOW

Four score and seven minutes ago (about an hour and a half) your physician brought forth, upon her desk, a new prescription, conceived in best medical practice, and dedicated to the proposition that all generics are created equal. Now we are engaged in a great civilian war, testing whether that medication, or any medication so conceived, and so dedicated, can help us long endure. And maybe we can feel good at the same time. For forty years as a pharmacist, I've been building bridges - from the doctor to those in need of important drug information - you. With respect for the listener, and from the perspective that it is better to apply a recommended course of therapy than it is to comply with an ordered course, the goal here is not to provide specific answers about your drug therapy, but rather to help you generate the questions that will that will empower you in this. Toward that end, there will be weekly podcasts, very often with guests who will be "the people".

HOSTED BY

Donald Schoeff R.Ph.

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