PODCAST · health
Endometriosis Uncovered
by Salman Okour.MD
Discussion about recent research articles about endometriosis ,interviews with experts and patients
Episodes
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Episode 32: why colonoscopy often misses bowel endometriosis
This clinical study investigated the effectiveness of colonoscopy in detecting intestinal endometriosis among patients already diagnosed with deep pelvic endometriosis. Researchers evaluated 174 female patients by comparing their preoperative colonoscopic findings against the gold standards of...
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Episode 31 : Endometriosis Lesions dont correlate with symptomes
A retrospective study investigated 234 women diagnosed via ultrasound with adenomyosis and endometriosis to determine whether pain intensity and hormone therapy response correlate with disease extension or specific lesion locations. The findings reveal that while lesion coexistence is extremely...
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Episode 30: Recurrence after surgery for endometrioma
This systematic review and meta-analysis evaluates the likelihood of endometrioma recurrence in women who undergo surgery without subsequent hormonal suppression. By analyzing 55 studies, researchers determined that the risk of a new ovarian cyst forming increases steadily over time, reaching a...
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Episode 29 : Diaphragmatic Endometriosis ,Review of single center experience with 60 cases
This retrospective study evaluates the feasibility and safety of robotic-assisted surgery for treating severe diaphragmatic endometriosis, a rare condition that often causes shoulder and chest pain. Researchers analyzed 60 patients, finding that the robotic approach effectively manages complex...
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Episode 28 : Surgery VS ART For patients with DIE ,A Multicenter randomized controlled trial
Despite difficulty in recruitment for randmoized trials in patients with infertility and endometriosis ,this unique small RCT ,Shed some light of this important question . EFFORT study: Surgery vs assisted reproductive technology among women with deep endometriosis – A multicenter randomized...
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Episode 27 : Ten-Year Outcomes of Surgical Management for Rectal Endometriosis
This study by Roman et.al presents the ten-year follow-up results of a randomized controlled trial comparing conservative surgical excision to radical segmental resection for treating deep rectal endometriosis. Researchers found no statistically significant differences between the two methods...
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Episode 26 : SOGC Clinical Practice Guidelines for Endometriosis Management
These clinical guidelines from the Society of Obstetricians and Gynaecologists of Canada (SOGC) offer a comprehensive framework for the diagnosis and management of endometriosis. Developed by a specialized working group, the document emphasizes patient-centered care through early identification,...
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Episode 25 : Central Sensitization and Hormonal Therapy Failure in Endometriosis Pain
This prospective study explores why hormonal treatments sometimes fail to alleviate endometriosis-related pain. Researchers specifically examined central sensitization, a condition where the nervous system remains in a state of high reactivity, as a primary factor in treatment resistance. By...
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Episode 24: Surgical Outcomes for Isolated Superficial Peritoneal Endometriosis
This research article : Surgery for Pain Symptoms in Women With Isolated Superficial Peritoneal Endometriosis(JIMIG ,April,2026). examines the effectiveness of laparoscopic surgery for women suffering from isolated superficial peritoneal endometriosis (iSPE). By tracking 250 patients over several...
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Episdoe 23: The skeletal cost of Endometriosis drugs
A review of Recent article published in the green journal :Effect of Medical Therapies for Endometriosison Bone HealthA Systematic Review and Meta-analysis
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Episode 22: Endometriosis and Cancer Risk
This academic review examines the epidemiological and molecular link between endometriosis and an elevated risk of specific ovarian cancer subtypes, namely clear cell and endometrioid carcinomas. While research indicates a statistically significant increase in relative risk, the authors emphasize...
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Episode 21 : ESHRE 2017 Guidlines,Surgery for Endometrioma
This joint publication from major gynecological societies provides formal technical recommendations for the surgical management of ovarian endometriomas in patients of reproductive age. The document bridges a gap in existing literature by shifting focus from general diagnosis to the specific...
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Episdoe 20 : Consensus Guidelines for Pelvic Floor Botulinum Toxin Injection
The Podcast discuss a new publication tha introduces new consensus-based guidelines for using botulinum toxin A (BTA) to treat myofascial pelvic pain and other types of pelvic floor dysfunction. Developed through a modified Delphi method involving a panel of experts, these guidelines address the...
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Episode 19 : Efficacy of Dienogest Versus GnRH Agonists After Endometriosis Surgery: A Systematic Review and Meta-Analysis
discussion of a paper by Servidoni et.al comparing an commonly used oral medication dienogest (Visanne) and injection GnRH agonist ,considered a strong option for hormonal management of endometriosis pain or after surgery. revealing some surprising results.
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Episode 18: Systematic review of Endometriosis in teenagers with chronic pelvic pain
This systematic review examines the prevalence and severity of endometriosis among adolescents experiencing pelvic pain. By analyzing nineteen studies, researchers discovered that roughly 64% of symptomatic young women undergoing surgery were diagnosed with the condition. The findings indicate…
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Episode 17 : Ending the teenage endometriosis diagnostic delay
Imagine navigating adolescence while dealing with chronic, debilitating pain. This is the reality of endometriosis, a condition where tissue acting like the uterine lining grows outside the uterus.While medical science understands adult endometriosis better, research on teenagers remains in its...
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Episode 16: Ethanol sclerotherapy for endometriomas: a fertility-preserving alternative
This scientific review by J. Younis at Frontiers In reproductive health .explores ethanol sclerotherapy as a minimally invasive substitute for traditional surgery when treating ovarian endometriomas. While standard surgical excision can inadvertently damage healthy tissue and diminish fertility,...
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Episdoe15: Surgery Restore natural fertility In Endometriosis DIE Patients
A follow up of the ENDORE trial by H.Roman et.al ,This research study evaluates fertility outcomes for women undergoing surgery to treat deep colorectal endometriosis, specifically focusing on those who wish to conceive afterward. Researchers found that surgical intervention led to a high…
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Episdoe 14: Is endometriosis a progressive disease?
This review explores whether endometriosis is a progressive disease by examining the natural history of lesions through the lens of repeated tissue injury and repair (ReTIAR). Traditional staging systems often fail to predict disease outcomes because they rely on lesion size or volume, which are...
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Episdoe 13: Adenomyosis: Pathophysiology, Diagnosis, and Management Strategies
his clinical review by Kimberly.Koh et al in the green journal explores adenomyosis, a chronic condition where endometrial tissue grows within the uterine wall, causing pain, heavy bleeding, and infertility. While historically linked to older women, improved imaging technologies like specialized...
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Episdoe 12: Impact of Laparoscopic Sclerotherapy for Ovarian Endometriomas on Ovarian Reserve
This study by Crestani.et al at the jmig ,examines how laparoscopic sclerotherapy using a 95% ethanol solution affects the ovarian reserve in women being treated for deep endometriosis. By analyzing anti-müllerian hormone (AMH) levels before and after the procedure, researchers determined that…
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Episdoe 11: A Space Odyssey: Analysis of 3050 Laparoscopic Rectosigmoid Resections
This source is a retrospective clinical study published in the Journal of Minimally Invasive Gynecology that examines the outcomes of laparoscopic rectosigmoid resection for treating deep endometriosis. Researchers analyzed 3,050 patients over seventeen years to determine the effectiveness and...
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Episdoe 10 : Surgical Management of Ovarian Endometrioma and Reproductive Outcomes
These sources explore how different surgical treatments for ovarian endometriomas affect a patient’s ovarian reserve and future fertility outcomes. Clinical research indicates that while cystectomy is the standard approach for reducing recurrence, it often leads to a significant drop in...
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Episdoe 9: Long-term risk of repeate surgeries in women managed for endometriosis: a 1,092 patients study
This study by Professor Horace Roman et.al examines the long-term frequency of repeat surgeries for 1,092 patients who underwent complete endometriosis excision by a single specialist over nine years. Research indicates that the cumulative probability of requiring a second operation reaches 28%...
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Episode 8 : Why Your Brain amplifies your endometriosis pain
This research study explores the connection between deep endometriosis (DE) and central sensitization (CS), a condition where the nervous system amplifies the perception of pain. By comparing patients with severe disease to healthy individuals using the Central Sensitization Inventory…
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Episdoe 7: ABOG MOC Article : Comprehensive review of endometriosis care
Endometriosis is a complex, systemic inflammatory disease that affects approximately 10% of the reproductive-aged population and is frequently misunderstood as a simple localized issue. Recent medical reviews characterize it as an estrogen-dependent disorder where lesions act like rogue endocrine...
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Episode 6: ABOG MOC Article: Myfembree Article Review :Starving endometriosis without weakenning the bone ?
This clinical study investigates the effectiveness and safety of treating endometriosis-associated pain with a combination of elagolix and hormonal add-back therapy. Researchers conducted a twelve-month trial to determine if adding low doses of estradiol and norethindrone could reduce the bone...
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Episdoe 5: Pregnancy is not an endometriosis cure
This 2018 scientific review investigates whether pregnancy and breastfeeding truly provide therapeutic benefits for women with endometriosis. While medical professionals traditionally suggested that pregnancy could improve symptoms and shrink lesions, the authors found that these claims are…
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Episode 4: Ethanol injections save eggs in endometriosis surgery
This medical review examines ethanol sclerotherapy as a modern, less invasive alternative to laparoscopic cystectomy for treating ovarian endometriomas. While surgery is the traditional standard, it often causes iatrogenic damage to healthy tissue and reduces a woman's ovarian reserve. The…
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Episode 3: Medical therapy For Endometriosis
In this episode we discuss a review article about medical therapy role in endometriosis managment.Article by Jacques Donnez and Marie-Madeleine Dolmans in the journal of clinical medicine.
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Episode 2: ACOG clinical practice guidlines : Endometriosis diagnosis
We discuss the recent ACOG clinical practice guidline about Endometriosis diagnosis,the publication generated mixed reactions ,but most agree it is a step in the right direction .
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Episode 1 : Adenomyosis Is a teen age disease
Endometriosis in teens is more common than we once believed—and it’s time we start paying attention. This podcast explores the latest evidence showing that pelvic pain in adolescents is often dismissed, delaying diagnosis and care. we uncover how early recognition can change the trajectory of…
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