JNIS Podcast

Achieving near-complete reperfusion in medium vessel occlusions (MeVO) is linked to smaller final infarct volumes.  However, this did not translate into a statistically significant shift in 90-day functional independence.   In this episode,  JNIS Editor-in-Chief, Dr. Michael Chen, and Professor Johanna Ospel (1) discuss the post-hoc analysis of the ESCAPE-MeVO trial, titled "Reperfusion grade and clinical outcome following medium vessel occlusion thrombectomy in the Endovascular Treatment to Improve Outcomes for Medium Vessel Occlusion trial".  Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ. (1) Clinical Associate Professor at the University of Calgary and Senior Lecturer at the University of Basel. The JNIS Podcast is produced by Letícia Amorim, and is edited by Pritesh Kapadia.

Headache affects up to 90% of patients following aneurysmal subarachnoid hemorrhage (aSAH), often requiring high-dose opioids that can complicate neurological monitoring.  In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, is joined by Professor Peter Kan¹ to discuss a prospective pilot study investigating a novel dural therapy: the infusion of lidocaine (with or without dexamethasone) via the middle meningeal artery (MMA) during aneurysm embolisation.  They explore the safety of this targeted approach, its impact on Visual Analog Scale (VAS) pain scores, and its potential as an opioid-sparing strategy in the neuro-ICU. Link to the discussed paper: "Middle meningeal artery infusion for headaches after aneurysmal subarachnoid hemorrhage: a pilot study". Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ. (1) Department of Neurosurgery, The University of Texas Medical Branch at Galveston, Texas, USA

Can aqueductal stenosis be treated through a minimally invasive endovascular approach without transgressing brain parenchyma? In this episode, JNIS Editor-in-Chief, Dr. Michael Chen, speaks with neuro-interventional radiologist Dr. Michal Obrzut¹ about a neurointerventional approach to the management of obstructive hydrocephalus secondary to aqueductal stenosis. The author describes the underlying concept, technical feasibility in cadaveric models, and potential implications for minimally invasive neurosurgical practice. Link to the discussed paper: "A novel neurointerventional subarachnoid aqueductoplasty technique for the treatment of aqueductal stenosis: a cadaveric feasibility study"   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.   (1) Neurosurgery, Cleveland Clinic Florida, Weston, Florida, USA          

Medical professionals can oftentimes fall under the category of "second victims", as they experience burnout and moral injury from the impacts of their work. Over the course of a neurointerventionalist's medical career, serious complications in procedures are sadly inevitable. These can be difficult to process, and there are not always the systems in place to provide the support needed, either inside or outside of the hospital. A new survey has been carried out to assess the severity and prevalence of negative psychological effects on physicians who have experienced these complications. Dr. Ansaar Rai¹ joins JNIS Editor-in-Chief Dr. Michael Chen to discuss the original research piece, "Unseen wounds: a multinational investigation of neurointerventionalists on the psychological toll of complications".  (1) Interventional Neuroradiology, West Virginia University Rockefeller Neuroscience Institute, Morgantown, West Virginia, USA Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

. Dr Donald Heck (1) and Dr Peter Kan (2) join JNIS Editor-in-Chief Dr. Michael Chen to discuss the commentary “Middle meningeal artery embolization in the routine care of chronic subdural hematoma?” by D.V. Heck et al. They highlight key debates around efficacy, safety, and workflow integration as embolization moves closer to becoming a routine therapeutic option. (1) Triad Radiology Associates, Novant Health Forsyth Medical Center, Winston Salem, North Carolina, USA (2) Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Pulsatile tinnitus — the perception of a rhythmic sound in sync with the heartbeat — can be a key indicator of underlying vascular or structural pathology. In this episode, JNIS new Editor-in-Chief Dr. Michael Chen speaks with Dr. Madhavi Duvvuri and Dr. Matthew Robert Amans, authors of Non-invasive imaging modalities for diagnosing pulsatile tinnitus: a comprehensive review and recommended imaging algorithm. They are both from the University of California San Francisco, USA. They discuss the current evidence base, highlight the strengths and limitations of non-invasive imaging techniques such as MRI, MRA, CT, and CTA, and outline a practical algorithm for streamlining diagnosis.    Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

In the SCENT trial, researchers investigated the effects of the Surpass flow diverter system for treating wide-necked aneurysms. Five-year results of this trial have recently been published in JNIS, presenting the safety and effectiveness outcomes of treatment with the Surpass Streamline flow diverter system. The study analyses the rates of aneurysm occlusion and adverse events.   Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Philip Meyers¹, author of the paper: Five-year results of the SCENT trial with Surpass flow diverters to treat large or giant wide-neck aneurysms   1. Radiology and Neurological Surgery, Columbia University, New York, USA   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

High risk factors for stroke such as smoking and blood pressure are not equally represented throughout the patient population. These are just two of the socioeconomic influences on cerebrovascular disease. One way to view this association is through the lens of the Area Deprivation Index (ADI), a measure of neighbourhood-level deprivation, and this was the approach of the study discussed in this episode. The study evaluated the association between the ADI and the treatment of ruptured intracranial aneurysms compared with unruptured intracranial aneurysms across multiple centres. Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Alexandra Paul¹, author of the paper: Multicenter study of association between socioeconomic status and treatment of ruptured cerebral aneurysms compared to unruptured cerebral aneurysms: insights from 4,517 patients using the area deprivation index   1. Department of Neurosurgery, Albany Medical Center, Albany, New York, USA   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

The "River" stent is a novel stent designed specifically to account for the anatomical and procedural requirements of venous sinus stenosis. A multicentre study of the device's safety and efficacy is underway, comprising 39 subjects across 5 US centres. The 1-year results have been recently published in JNIS. Editor-in-Chief of JNIS, Dr. Felipe C. Albuquerque, interviews Dr. Athos Patsalides¹, author of the paper: The River study: the first prospective multicenter trial of a novel venous sinus stent for the treatment of idiopathic intracranial hypertension 1. Department of Neurological Surgery, North Shore University Hospital, Manhasset, New York, USA   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Observations from practice and data analysis have shown that the duration of mechanical thrombectomy procedures are a strong predictor of outcome even with successful procedures. A large multicenter study was conducted which gives insight into choices between catheter types, and strategic decisions to be made during prolonged procedures. Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Ali Alawieh¹ and Dr. Alejandro Spiotta²,  two authors of the paper:  Prolonged intracranial catheter dwell time exacerbates penumbral stress and worsens stroke thrombectomy outcomes   1. Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA 2. Med Univ S Carolina, Charleston, South Carolina, USA   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

The use of assistive devices when treating unruptured aneurysms is widespread in neurointerventional practice. But there is no standard for how long patients should receive dual anti-platelet therapy after the procedure, to protect them from thrombotic complications. Durations can range from one month to one year. This episode looks at a review of patient data across 12 locations to understand the effect of therapy duration on risk of complications.  Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Andrew Ringer¹, first author of the paper:  Impact of duration of dual anti-platelet therapy on risk of complications after stent-assisted coiling of unruptured aneurysms 1. Mayfield Clinic, Cincinnati, Ohio, USA Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

There has been a large increase in the number of non-invasive neurovascular studies performed in the last decade, particularly CT angiograms and MR angiograms. What has this meant for catheter-based angiography? This episode looks at an analysis done on a large claims database in the USA, to observe trends in imaging modalities, as well as the distinctions in use by neurosurgeons and radiologists. Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr. Francis Jareczek¹ and Dr. D. Andrew Wilkinson¹, two of the authors of the paper:  National trends in catheter angiography and cerebrovascular imaging in a group of privately insured patients in the US. 1. Neurosurgery, Penn State Health Milton S Hershey Medical Center, Hershey, Pennsylvania, USA Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.  

Although many U.S. neurointerventionalists report at least one stressful malpractice claim over their career, the majority conclude without any court proceedings or direct repercussions in their practice. In this podcast, we look at the prevalence and causes of malpractice claims and complaints filed with state medical boards against neurointerventionalists, and some of the risk factors in an increasingly busier field. Dr Felipe C. Albuquerque, Editor-in-Chief of JNIS, interviews Dr Kyle M. Fargen (Wake Forest University, Winston-Salem); and Dr Joshua A. Hirsch (Massachusetts General Hospital, Boston), both members of the editorial board of the journal and the authors of the paper:  Medical malpractice claims and state medical board complaints among United States neurointerventionalists. Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ.

Single-stent assisted coiling techniques such as ‘L-stenting’ are an alternative to intrasaccular devices for wide-neck bifurcation aneurysms. In this episode, Aliya Siddiqui¹ and Dr. Reade De Leacy² join JNIS editor-in-chief Dr. Felipe Albuquerque to discuss the background and findings of their recent study, regarding the efficacy and safety of the 'L-stenting' technique.  Read the paper: A core-lab adjudicated analysis of single-stent assisted coiling of wide-neck bifurcation aneurysms 1. Medical College of Wisconsin, Milwaukee, USA 2. Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, USA Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ. Thank you for listening! This episode was produced and edited by Brian O'Toole. 

Patients with good motor function outcomes after aneurysmal subarachnoid hemorrhage treatment may still be left with neuropsychiatric effects. They can suffer from such difficult conditions as cognitive dysfunction, depression and sexual dysfunction. Not all of these patients will volunteer their symptoms unprompted on follow-up. This outcome type has had limited study, and became an interest of today's guest, Dr. Jose Danilo Bengzon Diestro (1). JNIS editor-in-chief Dr. Felipe Albuquerque speaks with him on this subject, based on the recently published paper, "Long-term neuropsychiatric complications of aneurysmal subarachnoid hemorrhage: a narrative review".   (1) Department of Medicine, University of Toronto, Toronto, Canada   Please subscribe to the JNIS podcast on your favourite platform to get the latest podcast every month. If you enjoy our podcast, you can leave us a review or a comment on Apple Podcasts (https://apple.co/4aZmlpT) or Spotify (https://spoti.fi/3UKhGT5). We'd love to hear your feedback on social media - @JNIS_BMJ. Thank you for listening! This episode was produced and edited by Brian O'Toole. 

Alis Dicpinigaitis (1) and Dr. Fawaz Al-Mufti (2) join JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, to discuss the study, "Mapping geographic disparities in treatment and clinical outcomes of high-grade aneurysmal subarachnoid hemorrhage in the United States". They explain the findings of their study, covering the predictive impact of factors including age, insurance status, race, and hospital ownership. Read the paper: https://jnis.bmj.com/content/early/2024/02/19/jnis-2023-021330  (1) New York Presbyterian - Weill Cornell Medical Center, New York, New York, USA (2) Department of Neurosurgery, Westchester Medical Center at New York Medical College, Valhalla, New York, USA Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767  Thank you for listening! This episode was produced and edited by Brian O'Toole. 

Dr. Michael Veldeman (1) joins JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, to discuss the study, "Intra-arterial nimodipine for the treatment of refractory delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage". Dr. Veldeman explains the methods of the study, the growing significance of computerised tomography perfusion imaging in diagnosis of unconscious patients, the use of induced hypertension, and interventional complications that arose when treating subarachnoid hemorrhage patients. Read the paper: https://jnis.bmj.com/content/early/2023/12/16/jnis-2023-021151  (1) Department of Neurosurgery, RWTH Aachen University Hospital Aachen, Aachen, Germany Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767  Thank you for listening! This episode was produced and edited by Brian O'Toole. 

JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, is joined from New York by Prof. David Fiorella (1) to discuss the paper, "Safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide necked bifurcation aneurysms: final 5 year results of the pivotal WEB Intra-saccular Therapy study (WEB-IT)". Prof. Fiorella explains the results of this extensive study across 27 locations, with the WEB device proving to be a durably effective and safe endovascular treatment option for wide-necked bifurcation aneurysms. Read the paper: https://jnis.bmj.com/content/15/12/1175  (1) Department of Neurosurgery, State University of New York at Stony Brook, Stony Brook, New York, USA Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767  Thank you for listening! This episode was produced and edited by Brian O'Toole. 

JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, is joined from Calgary by Dr. Johanna Ospel (1) to discuss "Recent developments in pre-hospital and in-hospital triage for endovascular stroke treatment", a paper detailing the many aspects of resource allocation when treating stroke patients.  Read the paper: https://jnis.bmj.com/content/early/2022/10/14/jnis-2021-018547 (1) Departments of Radiology and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767  Thank you for listening! This episode was produced and edited by Brian O'Toole. 

In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Michael Levitt (1) and Dr. Colin Derdeyn (2), authors of a pair of editorials discussing the practice of dural venous sinus stenting for patients with idiopathic intracranial hypertension.   Point: Dural venous sinus stenting should be considered a first-line treatment option for select patients with idiopathic intracranial hypertension https://jnis.bmj.com/content/early/2023/06/20/jnis-2023-020597  Counterpoint: stenting for idiopathic intracranial hypertension should be trialed https://jnis.bmj.com/content/early/2023/06/20/jnis-2023-020404    These articles are free-to-access for a month following the publication of this podcast.    Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767  Thank you for listening! This episode was edited by Brian O'Toole.    (1) Neurological Surgery, University of Washington School of Medicine, Seattle, Washington, USA (2) Radiology, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA

In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Marco Colasurdo (1) and Prof. Dheeraj Gandhi (2), authors of the original research article, "Predictors for large vessel recanalization before stroke thrombectomy: the HALT score" - https://jnis.bmj.com/content/early/2023/04/25/jnis-2023-020220 This paper is free-to-access for a month following the publication of this podcast.  Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767  Thank you for listening! This episode was edited by Brian O'Toole.  (1) Interventional Neuroradiology, Dept. of Diagnostic Radiology, Uni. of Maryland Medical Center, Baltimore, Maryland, USA  (2) Dept. of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, Connecticut, USA

In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Mariam Kyarunts(1) and Charlotte Michaelcheck(2), contributing authors to the recently published article "Gender disparities in industry compensation and research payments among neurointerventional surgeons in the USA" - https://jnis.bmj.com/content/early/2023/01/23/jnis-2022-019921 This paper is free-to-access for a month following the publication of this podcast. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was edited by Brian O'Toole. (1)Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA (2)Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA

In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Kyle Fargen(1) about the recently published study "Mechanical thrombectomy decision making and prognostication: Stroke treatment Assessments prior to Thrombectomy In Neurointervention (SATIN) study" - https://jnis.bmj.com/content/early/2023/01/05/jnis-2022-019741.long Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was produced and edited by Brian O'Toole. (1) Neurological Surgery and Radiology, Wake Forest University, Winston-Salem, North Carolina, USA

In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Amanda Baker(1) and Dr. Sandra Narayanan(2) about their recently published standard "Society of NeuroInterventional Surgery: position statement on pregnancy and parental leave for physicians practicing neurointerventional surgery" - https://jnis.bmj.com/content/15/1/5. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was edited by Brian O'Toole. (1) Radiology and Biomedical Imaging, UCSF, San Francisco (2) Neurointerventional Program and Comprehensive Stroke Program, Pacific Neuroscience Institute, Santa Monica

In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Krishna C. Joshi(1) and Dr. Michael Chen(2) about their paper "Endovascular thrombectomy for acute ischemic stroke in patients with cancer: a propensity-matched analysis" - https://jnis.bmj.com/content/14/12/1161. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was edited by Brian O'Toole. (1) Neurological Surgery, Rush University Medical Center, Chicago (2) Neurological Surgery, Rush University Medical Center, Chicago

In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, speaks with Dr. Matthew Amans(1) and Daniel Cummins(2) about their paper "Cerebrovascular pulsatile tinnitus: causes, treatments, and outcomes in 164 patients with neuroangiographic correlation" - https://jnis.bmj.com/content/early/2022/09/08/jnis-2022-019259. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was edited by Brian O'Toole. (1) School of Medicine, University of California, San Francisco, USA (2) Radiology and Biomedical Imaging, University of California, San Francisco, USA

The 2013 ARUBA trial concluded that medical management alone is superior to medical management with interventional therapy for patients with unruptured brain arteriovenous malformations. A study was conducted to analyze AVM treatment and epidemiologic response to the ARUBA trial. Following ARUBA, there has been a stark decrease in interventions for uAVMs. Nationwide rAVM discharge incidence is inversely correlated with uAVM intervention rate. Less uAVM interventions may lead to a substantial increase in AVM rupture incidence. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque speaks with Dr. Evan Luther(1) and Dr. Robert Starke(2) about their paper "Unruptured arteriovenous malformation intervention rate is inversely correlated with ruptured AVM discharge incidence" - https://jnis.bmj.com/content/12/suppl_1/a163. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was produced by Leticia Amorim and edited by Brian O'Toole. (1) Neurological Surgery, University of Miami, Miami, Florida, USA (2) Department of Neurosurgery & Radiology, Miller School of Medicine, University of Miami, Miami, Florida, USA

Survival for glioblastoma remains very poor despite decades of research, with a 5-year survival of only 5%. Technological improvements that have revolutionized treatment of ischemic stroke and brain aneurysms have great potential in providing more precise and selective delivery of cancer therapeutic agents to brain tumors. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque speaks with Dr. Stephen Chen (1)and Dr. Peter Kan (2) about their paper "Perfusion-guided endovascular super-selective intra-arterial infusion for treatment of malignant brain tumors". The paper describes a technique using perfusion guidance to enhance the precision of endovascular super-selective intra-arterial (ESIA) infusions of mesenchymal stem cells loaded with Delta-24 in the treatment of glioblastoma. This technique enhances targeted super-selective delivery of therapeutic agents for brain tumors. Paper available online (https://jnis.bmj.com/content/14/6/533) and in June print issue of JNIS. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was produced by Leticia Amorim and edited by Brian O'Toole. (1) Interventional Radiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA (2) Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA

The Woven EndoBridge (WEB) device has FDA approval for treatment of wide-necked intracranial bifurcation aneurysms. It has been shown to result in adequate occlusion in bifurcation aneurysms overall, but its usefulness in the individual bifurcation locations has been evaluated separately only in few case series, which were limited by small sample sizes. In this podcast, JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Dr. Nimer Adeeb (1)and Dr. Adam Dmytriw (2) on their paper "Comparing treatment outcomes of various intracranial bifurcation aneurysms locations using the Woven EndoBridge (WEB) device". Paper available online: https://jnis.bmj.com/content/early/2022/04/27/neurintsurg-2022-018694 Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767 Thank you for listening! This episode was edited by Brian O'Toole. (1) Departments of Neurosurgery and Neurointerventional Surgery, Louisiana State University Health Sciences Center (2)Neuroendovascular Program, Massachusetts General Hospital, Harvard University

Sex disparities in acute ischemic stroke outcomes are well reported with IV thrombolysis. Despite several studies, there is still a lack of consensus on whether endovascular thrombectomy (EVT) outcomes differ between men and women. In this podcast, we discuss the Selection for Endovascular Treatment in Acute Ischemic Stroke (SELECT) study, in which women had similar discharge outcomes as men following EVT, in a propensity-matched cohort, but the improvement from discharge to 90 days was significantly worse in women, suggesting the influence of post-discharge factors. JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Johanna Fifi (Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York) and Amrou Sarraj (Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, Ohio). Paper available online: https://jnis.bmj.com/content/early/2022/02/28/neurintsurg-2021-018348. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767. Thank you for listening!

In the latest podcast, we discuss the joint expedited recommendations from the European Stroke Organisation (ESO) and the European Society for Minimally Invasive Neurological Therapy (ESMINT) on indication for intravenous thrombolysis before mechanical thrombectomy in patients with acute ischemic stroke and anterior circulation large vessel occlusion. JNIS Editor-in-Chief, Dr. Felipe C. Albuquerque, interviews Dr. Guillaume Turc, Department of Neurology, GHU Paris Psychiatrie et Neurosciences, Université de Paris, and co-chair of the module working group. Paper available here: https://jnis.bmj.com/content/14/3/209. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get the latest episodes. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767. Thank you for listening!

Venous sinus stenting (VSS) is a safe, effective, and increasingly popular treatment option for selected patients with idiopathic intracranial hypertension (IIH). Serious complications associated with VSS are rarely reported. In this podcast, JNIS Editor-in-Chief, Felipe C. Albuquerque, interviews Dr. Kyle Fargen, from the Department of Neurosurgery, Wake Forest University, Winston-Salem, North Carolina, about a case series in which serious complications after VSS were identified retrospectively from multicenter databases. The cases are reviewed and learning points regarding complication avoidance and management are presented in his paper (https://jnis.bmj.com/content/early/2021/04/27/neurintsurg-2021-017361).

In this podcast, we discuss the COMPASS: a trial of aspiration thrombectomy versus stent retriever thrombectomy as first-line approach for large vessel occlusion, comparing patients with and without prior intravenous (IV) alteplase administration. JNIS Editor-in-Chief, Felipe C. Albuquerque, interviews Maxim Mokin, from the Department of Neurosurgery and Brain Repair, University of South Florida, Tampa, USA, about the post hoc analysis. which concludes that prior administration of IV alteplase may adversely affect the efficacy of aspiration, whilst it does not seem to influence the stent retriever first approach to MT in patients with anterior circulation ELVO. Read the related paper on the JNIS website: https://jnis.bmj.com/content/early/2021/10/13/neurintsurg-2021-017943

Flow diversion of intracranial aneurysms with the Pipeline Embolization Device (PED) is commonly performed, but the value of long-term angiographic follow-up has not been rigorously evaluated. The study discussed in this podcast examines the prevalence of actionable findings of aneurysm recurrence and development of in-stent stenosis in a cohort of patients that underwent long-term angiographic follow-up at multiple time points. JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Dr Akash P. Kansagra, from the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, USA. Related paper: https://jnis.bmj.com/content/early/2021/07/01/neurintsurg-2021-017745

Retinoblastoma is the most common primary intraocular malignancy in children. In this podcast, JNIS Editor-In-Chief Felipe C. Albuquerque and Pascal Jabbour discuss a study from July’s issue, concluding that local factors relating to the chemotherapy and selective microcatheterization of the ophthalmic artery are essential factors in the development of ophthalmic artery thrombosis, as seen by the association of ophthalmic artery thrombosis with the frequency of intra-arterial chemotherapy. Dr Jabbour, Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, USA, is the corresponding author of 'Incidence and predictors of ophthalmic artery occlusion in intra-arterial chemotherapy for retinoblastoma' - https://jnis.bmj.com/content/13/7/652

In this podcast, JNIS Editor-In-Chief Felipe C. Albuquerque and Adnan Siddiqui discuss a case series that describes complete flow control using concurrent transient rapid ventricular pacing with afferent arterial balloon flow arrest technique as “safe and feasible” for transvenous embolization of select cerebral arteriovenous malformations (AVM). Dr Siddiqui (Department of Neurosurgery, University at Buffalo, NY, USA) is the lead author of “Complete flow control using transient concurrent rapid ventricular pacing or intravenous adenosine and afferent arterial balloon occlusion during transvenous embolization of cerebral arteriovenous malformations: case series”, published in the April 2021 issue of JNIS. Link to the paper: https://jnis.bmj.com/content/13/4/324

JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Sami Al Kasab and Alejandro Spiotta, both from the Medical University of South Carolina, Charleston, USA. They discuss the Stroke Thrombectomy and Aneurysm Registry data showing an “alarming downtrend in mechanical thrombectomy rates in African American patients during the COVID-19 pandemic”. Read the related article online (https://jnis.bmj.com/content/early/2021/01/06/neurintsurg-2020-016946) and in the March issue of JNIS. Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Operating rooms contribute between 20% to 70% of hospital waste. Neurointerventional procedures, in particular, generate a substantial amount of that waste: an average of 8 kg per case, recently aggravated by the COVID-19 pandemic. JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Pey Ling Shum, Monash Health, Clayton, Victoria, Australia, about her recent paper “Environmental sustainability in neurointerventional procedures: a waste audit” - https://jnis.bmj.com/content/12/11/1053 Please also read the related commentary "Greening the neurointerventional suite" - https://jnis.bmj.com/content/12/11/1037 Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

Sexism is common place in one of the most male-dominated subspecialties in medicine. Despite this, the prevalence of women physicians in neurointervention is steadily rising. In this podcast, JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews neurointerventionalists Stephanie H Chen - Department of Neurological Surgery, University of Miami School of Medicine - and Marie-Christine Brunet - Department of Neurological Surgery (NEUR) at McGill University - about the challenges of being a female physician in this field. They are the authors of the first study examining the amount of maternal and fetal radiation exposure during a pregnant neurointerventional fellow’s training. Spoiler alert: the findings suggest that, when optimal radiation safety practices are implemented, the fetal dose of a pregnant neurointerventionalist is negligible. Read the paper for free for a month on the JNIS website: https://jnis.bmj.com/content/12/10/1014 Please subscribe to the JNIS Podcast via all podcast platforms, including Apple Podcasts, Google Podcasts, Stitcher and Spotify, to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the JNIS Podcast iTunes page: https://podcasts.apple.com/gb/podcast/jnis-podcast/id942473767

The recommendations resulting from the report of the SNIS Standards and Guidelines Committee on transarterial access are discussed in this podcast. JNIS Editor-In-Chief, Felipe C. Albuquerque, interviews Robert Starke (University of Miami MILLER School of Medicine, Miami Beach, Florida, and Westchester Medical Center, Valhalla, New York) and Justin Fraser (University of Kentucky, Lexington), who recently published the paper “Transarterial and transvenous access for neurointerventional surgery: report of the SNIS Standards and Guidelines Committee” on behalf of the Society of NeuroInterventional Surgery. Read the paper on the JNIS website: https://jnis.bmj.com/content/12/8/733

JNIS Editor-In-Chief Felipe C. Albuquerque discusses idiopathic intracranial hypertension (IIH) and a new patient classification paradigm with Kyle Fargen (Neurological Surgery, Wake Forest University, Winston-Salem, USA) and Michael Levitt (Neurological Surgery, University of Washington, Seattle, USA). Both authors recently wrote about the intersection between IIH and venous sinus stenosis, an increasingly hot topic within the neurointerventional community. In the podcast, the participants discuss this novel classification, venous sinus stenting, and issues pertaining to this diverse patient population. Read the paper and the commentary on the JNIS website: Idiopathic intracranial hypertension is not idiopathic: proposal for a new nomenclature and patient classification https://jnis.bmj.com/content/12/2/110 Commentary: Another version of the truth https://jnis.bmj.com/content/12/4/335

In a densely populated setting, for patients with stroke who are endovascular therapy candidates and closest to a primary stroke center from the field, triage to a slightly more distant comprehensive stroke center is associated with faster time to endovascular therapy, no delay to alteplase, and less disability at 90 days. Felipe de Albuquerque talks to Mahesh Jayaraman and Ryan McTaggart (Department of Diagnostic Imaging, Warren Alpert Medical School of Brown University, Rhode Island, USA) about their paper “Field triage for endovascular stroke therapy: a population-based comparison”, which is part of the March issue of JNIS and can be read for free on the journal's website: https://jnis.bmj.com/content/12/3/233.

In this podcast, Felipe de Albuquerque talks to Istvan Szikora, Neurointerventions, National Institute of Clinical Neurosciences, Budapest, Hungary, about the official document of Standards for European training requirements in interventional neuroradiology guidelines by the Division of Neuroradiology/Section of Radiology European Union of Medical Specialists (UEMS), in cooperation with the Division of Interventional Radiology/UEMS, the European Society of Neuroradiology (ESNR), and the European Society of Minimally Invasive Neurological Therapy (ESMINT). Read the paper on the JNIS website: https://jnis.bmj.com/content/early/2019/11/15/neurintsurg-2019-015537 .

In this podcast, Editor-in-Chief of JNIS Felipe C. Albuquerque talks to Justin F. Fraser, Neurological Surgery, University of Kentucky, about the current endovascular strategies for posterior circulation large vessel occlusion stroke: the report of the Society of NeuroInterventional Surgery Standards and Guidelines Committee. Read the paper for free on the JNIS website: https://jnis.bmj.com/content/11/10/1055.

In this podcast, Editor-in-Chief of JNIS Felipe C. Albuquerque talks to Eric Peterson (University of Miami MILLER School of Medicine, Miami, Florida, USA) about the novel technique of distal transradial access in the diagnostic cerebral angiography. The paper is the Editor’s Choice article of the July issue of JNIS. Read it online: https://jnis.bmj.com/content/11/7/710.

Although the impact of Brexit on research is still unknown, BMJ’s CEO Peter Ashman is confident medical publishing “will be OK”. In this special podcast, Publishing Director of BMJ, Allison Lang, assures the American audience of JNIS that the turmoil in the UK over leaving the European Union should have no impact on the specialty journals of the BMJ Publishing Group.

In the January 2019 podcast, Felipe C. Albuquerque talks to Reade De Leacy about the BRANCH (wide-neck bifurcation aneurysms of the middle cerebral artery and basilar apex treated by endovascular techniques)- a multicentre, retrospective study comparing core lab evaluation of angiographic outcomes with self-reported outcomes. Read the JNIS Editor's Choice paper here: https://jnis.bmj.com/content/11/1/31.

There are two editor's choice papers of the November issue of JNIS discussed in this podcast. Editor-in-Chief of JNIS, Felipe de Albuquerque, talks to Ashutosh Jadhav and Shashvat Desai, both from the Department of Neurology, University of Pittsburgh Medical Center, Pennsylvania, USA. They are co-authors of the papers: Thrombectomy 6-24 hours after stroke in trial ineligible patients (https://jnis.bmj.com/content/10/11/1033) Thrombectomy 24 hours after stroke: beyond DAWN (https://jnis.bmj.com/content/10/11/1039).

The recommendations of the report of the Society of Neurointerventional Surgery (SNIS) Standards and Guidelines Committee for endovascular strategies for cerebral venous thrombosis are discussed in this podcast. Editor-in-Chief of JNIS, Felipe de Albuquerque, talks to Justin Fraser (Department of Neurological Surgery, University of Kentucky, Lexington, USA) on behalf of the Society of NeuroInterventional Surgery. Read the paper on the JNIS website: https://jnis.bmj.com/content/10/8/803

M2 occlusions can present with serious neurological deficits, resulting in large infarcts and significant morbidity and mortality. The paper discussed in this podcast concludes that patients with M2 occlusions and higher baseline deficits (NIHSS score ≥9) may benefit from endovascular therapy, thus potentially expanding the category of acute ischemic strokes amenable to intervention. Listen to the conversation between the Editor-in-Chief of JNIS, Felipe de Albuquerque, and Ansaar Rai (Department of Interventional Neuroradiology, West Virginia University Hospital, USA), who is the co-author of “A population-based incidence of M2 strokes indicates potential expansion of large vessel occlusions amenable to endovascular therapy”. Read the Editor’s Choice paper of June 2018 on the JNIS website: jnis.bmj.com/content/10/6/510.