PODCAST · health
Medical Minds
by Garvan Institute of Medical Research
We dive deep into the minds of our amazing researchers to find out how they tick and how they are working to make our lives better.
Episodes
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Finding the needle in the haystack
Autoimmune diseases affect one in eight people, yet many are still treated by suppressing the entire immune system. But what if all of them shared a common root cause – a small number of rogue immune cells that could be identified and removed? In this episode, Garvan's Professor Chris Goodnow...
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Storming the tumour fortress
Pancreatic cancer can surround itself with dense scar tissue, creating a kind of fortress that makes tumours incredibly difficult to treat. So, how do we find a way through? In this episode, Garvan researcher Dr Brooke Pereira explains the role of this complex tumour environment, and reveals how...
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Hunting hidden cells
Our immune system is like a well-trained security network, constantly scanning the body for threats. So, how is it that some harmful cells manage to slip by unnoticed? In this episode, we speak to computational biologist, Dr Clare Puttick, about how cancer cells can evade detection by disrupting...
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The missing piece of the puzzle
What if the missing piece in diagnosing, and even treating, a rare disease was hiding in plain sight? For one such condition, mevalonate kinase deficiency, which affects at least one in a million people globally, that piece may now have been uncovered. In this episode, Garvan's Professor Mike...
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Calling killer cells to action
Immunotherapy has revolutionised the treatment of many blood cancers, harnessing the immune system so our bodies can fight back. But for solid tumours, like pancreatic cancer with a survival rate of just 13%, that breakthrough has remained frustratingly out of reach. In this episode, we explore…
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Arthritis: uncovering pathways to better treatment
Arthritis affects millions of people, but the underlying causes are still not fully understood. What makes the immune system that normally protects us suddenly attack our joints? And why do arthritis flares seem to arrive without warning? In this episode, we explore how certain immune cells or...
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Liver cancer: discovering the next generation of therapy targets
For decades, the fight against cancer has focused on killing the tumour cell. We treated cancer like an isolated entity that needed to be destroyed – but what if we’ve been looking at the wrong target? In this episode, we delve into the critical insight that cancer is not just a rogue cell – it’s...
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Biologics- engineering tomorrow’s medicines
Therapies and drugs have evolved enormously in the last 30 years. For example, in cancer, where previously our options were limited to surgery, chemotherapy and radiotherapy, we’re now hearing terms like cancer immunotherapy, targeted therapies and even cancer vaccines. Many of these are…
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Breaking the barriers to treating pancreatic cancer
Pancreatic cancer is one of the toughest cancers to treat – it’s aggressive, often diagnosed late, and doesn’t respond well to standard therapies. In this episode, we meet Professor Marina Pajic who is working at the cutting-edge of science to transform how we understand and treat this disease....
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Accelerating discovery, empowering translation
Garvan is one of Australia's largest independent medical research institutes with a single focus: to make discoveries that will improve health for all. In this episode, you’ll hear from Executive Director Professor Benjamin Kile on how he came to be at Garvan's helm and his strategy for driving...
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Trailer - Dr Kishore Kumar
Support Garvan research: https://www.garvan.org.au/support-us/give-now See omnystudio.com/listener for privacy information.
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Hope for Parkinson's, ataxia and dystonia
In Australia alone, 50 people are diagnosed with Parkinson's every day. Therapy options are limited, as they are for other movement and muscle disorders, such as ataxia and dystonia. In this episode of Medical Minds, we meet neurologist and researcher Associate Professor Kishore Kumar, who is...
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Trailer - Professor Thomas Cox
Support Garvan research: https://www.garvan.org.au/support-us/give-now See omnystudio.com/listener for privacy information.
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Breaking down cancer's defence mechanisms
The human body has an incredible capacity to heal itself – whether it’s a paper cut, a broken bone, or your lungs recovering after a chest infection. But not all types of healing are good for us. Cancers seem to have hijacked the healing process to protect themselves from treatments and to spread...
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New hope for multiple sclerosis
More than 33,000 people in Australia today are affected by multiple sclerosis, a disabling disease of the brain and spinal cord, for which there is no cure. In this episode, you’ll meet Dr Seyhan Yazar and Professor Tri Phan who are working to better manage, treat and prevent MS, by investigating...
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How AI is transforming cancer research
Scientific advances have led us to diagnosing, treating and preventing cancer much better than ever before. Still, 10 million people die of cancer every year and what we need now are transformative ideas. In this episode you’ll hear from Dr Amanda Khoury and Dr Braydon Meyer who are using AI to...
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Can genomics help treat inflammatory bowel disease?
Our gastrointestinal system contains more than 70% of the body’s immune cells and can house more microbial cells than there are human cells in our entire body. Unravelling all that complexity is more important than ever, with conditions affecting the gut, such as Crohn’s and ulcerative colitis…
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Giving cancer no place to hide
The relief of a successful cancer treatment is all too often marred by a distressing, lingering uncertainty of whether a cancer will return. Cancer cells can tuck away and lie dormant for years before waking up to spread once again. In this episode we speak to Professor Peter Croucher who is...
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Pushing the limits of genomics
Genomics is fundamentally changing the way we think about health and disease and driving forward personalised treatment options that would have been pure science fiction just a few years ago. Still, some parts of our genome are more ‘mysterious’ than others. In this episode, we meet Garvan...
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How are genes linked to disease?
Every day, we accumulate trillions of mutations in our body’s genetic material. How does our body stay the course amidst this constant genetic change and what's the link between our genes and our well-being? In this episode we speak to clinician researcher Associate Professor Owen Siggs who...
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Tackling pancreatic cancer
If you’ve ever seen an image of fluorescent cancer cells under the microscope, you may agree that it’s hard to understand how something so beautiful could be so deadly. In this episode, we speak to Professor Paul Timpson who is visualising pancreatic cancer in vivid detail to understand what the...
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Immunity under the microscope
A few hundred years ago, the idea of cells moving around in your body, protecting you from disease would have seemed like complete fantasy. Today, we don’t just know those remarkable cells exist – but we can visualise them in vivid detail. In this episode we meet Professor Tri Phan, a...
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Charting an 'atlas' of breast cancer
A tumour is often thought of as a kind of chaotic tissue – cancer cells multiplying without control or reason, wreaking havoc in the body with devastating outcomes. In this episode we speak to Professor Alex Swarbrick who is charting an ‘atlas’ through that chaos, using cutting-edge genomic...
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What’s the link between blood sugar and dementia?
Thanks to technology and the convenience of our modern lifestyle, we are far less active today than previous generations. But how have our bodies adjusted to that massive physical slow-down? In this episode, we speak with endocrinologist and clinical scientist Professor Katherine Samaras, who is...
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Slowing down cancer cells
There's no doubt that medical research is accelerating – thanks to cutting-edge technology we can do experiments faster, at a bigger scale and crunch more data more efficiently. But today we're talking to Associate Professor Liz Caldon, who is slowing down her experiments to understand how we can...
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Tackling rare immune disease
APDS is a rare inherited immune condition that has been reported in less than 300 people worldwide. So how could studying it help improve outcomes for the millions of people who live with autoimmune disease? Today, we meet A/Prof Elissa Deenick, a researcher who is taking a deep dive into the...
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Solving the immune system puzzle
Inside your blood stream, billions of immune cells are working hard to protect you – from bacteria, viruses, fungi, toxins – anything that could disturb your body's delicate balance. But how does this immune protection work? Today, we meet Professor Stuart Tangye, a scientific detective who is...
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A world of information in a single cell
Imagine being able to explore the fascinating world of individual cells and their genomic makeup, to unravel the mysteries hidden within our cells and to uncover the intricate mechanisms that cause disease. Today we meet Professor Joseph Powell, a cellular genomic scientist working on…
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Editing the immune system
The immune system is a complex network designed to protect our bodies from harmful invaders. But sometimes it can turn on us attacking our own cells and in doing so, causing autoimmune disease. Over the last 50 years, research into our immune system has advanced to identify particular drivers…
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Pandemic game changer: a universal vaccine for COVID-19
In early 2020, the world was plunged to the start of a pandemic that has affected every aspect of our lives. We’ve come to realise how vulnerable we are to viruses. The pandemic has also brought so much more science into awareness, with bell curves and an understanding of immunology than we’ve…
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What happens when the immune system doesn't function
Right this second, your immune system is protecting you from all the many potential bugs and foreign particles that can make you sick – bacteria, viruses, fungi, pollen, even food. When you’re healthy, you don’t realise how much work your immune system is doing to keep these nasties away. But if...
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On the case: solving genetic mysteries
One heart attack in a young family member is an unexpected shock. Two is a terrible coincidence that raises the heckles, but three that sounds like a genetic mystery. In this episode we talk researcher and cardiac genetic counsellor Associate Professor Jodie Ingles, who works with patients to...
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Can type 1 diabetes be cured?
Imagine seeing 20 years of hard work come together to help possibly thousands of people living with type 1 diabetes. Today we talk to Professor Shane Grey, who is experiencing just that. His autoimmune research has led to the discovery of a way to transplant the cells that produce insulin…
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Big data making big discoveries possible
The Human Genome project was a $3 billion global endeavour which launched in 1990 and took 13 years to complete. But now thanks to rapid and continuing advances in technology, we can sequence a whole human genome in just a matter of hours. In this episode, we talk to Associate Professor Sarah...
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Curing cancer, from bench to bedside
Medical research sits at the intersection of the lab and the clinic. It's critical for translating breakthrough science into possible treatments for people. It's most successful when scientists and clinicians collaborate. Today, we're talking with Professor Anthony Joshua, one of Australia's...
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New ways of treating breast cancer
Breast cancer is one of the most studied and high-profile cancers, and yet we still have so much to learn. While we have come such a long way and so many lives have been saved by advances in research, there’s still some breast cancers that are aggressive and don’t respond to treatment. Today…
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Trailer - Daniel MacArthur - Medical Minds
Support Garvan research: https://www.garvan.org.au/support-us/give-now See omnystudio.com/listener for privacy information.
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Bringing equity and diversity to genomic medicine
For science to advance in big leaps, you need people who not only have a mind for the detail, but also the big picture, and the passion to make big things happen. We talk with a researcher who has big goals to bring equity and diversity into genomic medicine in Australia, something surprisingly...
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Frequently Asked Questions
How many episodes does Medical Minds have?
Medical Minds currently has 38 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.
What is Medical Minds about?
We dive deep into the minds of our amazing researchers to find out how they tick and how they are working to make our lives better.
How often does Medical Minds release new episodes?
Medical Minds has 38 episodes. Check the episode list to see recent publication dates and frequency.
Where can I listen to Medical Minds?
You can listen to Medical Minds on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.
Who hosts Medical Minds?
Medical Minds is created and hosted by Garvan Institute of Medical Research.
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