Skip to content
PodParley
Questioning Medicine podcast artwork

PODCAST · health

Questioning Medicine

by Questioning Medicine

Join Andrew on a medical rollercoaster as we ask a medical question and answer it based on recent published papers.

Publisher-supplied feed metadata · PodParley refreshed Oct 15, 2026 · Source feed

Subscribe · 0 Bookmark

Episodes

  1. Episode 438: 445. GLP1 CME

    OMED GLP1 CME

  2. Episode 437: 444. Monday Morning Articles

    Silvain J, et al. Discontinuation of β-blockers in stable patients with previous myocardial infarction, preserved left ventricular ejection fraction, and no heart failure: A pooled analysis of individual patient data. Lancet 2026 Aug 30; [e-pub]. DOI: 10.1016/S0140-6736(26)01426-1. PubMed...

  3. Episode 436: 443. Fast 5 Medical Article Review

    Kanwal F, et al. Clinical care pathway for the risk stratification and management of patients with metabolic dysfunction–associated steatotic liver disease. Gastroenterology 2026 Jul; 171:164. DOI: 10.1053/j.gastro.2026.01.047. PubMed - MASLD screening and treatment recommendations. CT detected...

  4. Episode 435: 442. 7 article review

    we unpack whether rivaroxaban followed by aspirin improves thromboprophylaxis after hip and knee arthroplasty, put oral GLP-1 therapy orforglipron head-to-head with dapagliflozin for type 2 diabetes, and examine new evidence on venous thromboembolism after mechanical restraint in psychiatric...

  5. Episode 434: 441. Coronary Artery Calcium (CAC) -- Yacky Yack, the details on CAC

    Does a Coronary Artery Calcium (CAC) scan still earn its place in modern cardiovascular prevention? This podcast cuts through the headlines to examine the recent research, challenge overconfident conclusions, and put CAC testing under the microscope alongside the PREVENT risk equation. Each…

    more

  6. Episode 433: 440. CME Understanding Medical Stats

    OMED lecture on how to understand medical stats

  7. Episode 432: 439. 6 articles in 2026

    CME

  8. Episode 431: 438. CME- What To Do AFTER PE Diagnosis

    OMED lecture

  9. Episode 430: edit fix 437. A Brief Review of the Medical Literature!

    Xin X, et al. Optimal exercise modalities and dosages for blood pressure reduction in adults with prehypertension and established hypertension: A network meta-analysis and dose–response relationship study. J Am Heart Assoc 2026 May 14; 15:e044003. DOI: 10.1161/JAHA.125.044003. Vosooney A, et al....

  10. Episode 430: 437. A Brief Review of the Medical Literature

    Xin X, et al. Optimal exercise modalities and dosages for blood pressure reduction in adults with prehypertension and established hypertension: A network meta-analysis and dose–response relationship study. J Am Heart Assoc 2026 May 14; 15:e044003. DOI: 10.1161/JAHA.125.044003. Vosooney A, et al....

  11. Episode 429: 436. postpartum burnout., asundexian, semaglutide and ETOH, neck infection, varenicline

    Jafari K, et al. Risk factors for pediatric deep neck infection revisit after emergency department discharge for pharyngitis or localized neck symptoms. Ann Emerg Med 2026 May; 87:605. DOI: 10.1016/j.annemergmed.2025.10.007. In a “look-back” analysis of some 800 children admitted with deep neck...

  12. Episode 428: 435. Evolocumab, Statin and CKD, PCN allergy, MRI vs Rotator Cuff

    https://pubmed.ncbi.nlm.nih.gov/41903215/ Evolocumab to Reduce First Major Cardiovascular Events in Patients Without Known Significant Atherosclerosis and With Diabetes: Results From the VESALIUS-CV Trial https://pubmed.ncbi.nlm.nih.gov/41769754/ Association between statin therapy as primary...

  13. Episode 427: 434. 6 Articles From Arb to Patient Perspective to Cervical Cancer Screening

    https://agsjournals.onlinelibrary.wiley.com/doi/10.1111/jgs.70463 Angiotensin Receptor Blockers Versus Calcium Channel Blockers for First-Line Antihypertensive Therapy and Survival in Adults Aged 75Years or Older...

  14. Episode 426: 433. Salt, Statins, and Stents

    Donato J, et al. Things We Do For No Reason™: Low salt diets for patients with acute heart failure. J Hosp Med 2026 Feb 4; [e-pub]. DOI: 10.1002/jhm.70278. Some guidelines now recommend "normal sodium intake" for patients with acute and chronic HF, which means avoiding excessive sodium intake and...

  15. Episode 425: 432. CME LECTURE- Under Pressure, Blood Pressure

    432. CME LECTURE- Under Pressure, Blood Pressure

  16. Episode 424: 431. Gout should we treat to a number? Is Co-testing needed?

    https://www.sciencedirect.com/science/article/abs/pii/S2665991326000342?via%3Dihub lancet rheumatology A treat-to-target strategy versus symptom-driven management of gout in the Netherlands (GO TEST Overture): a multicentre, open-label, pragmatic, superiority, randomised controlled trial The...

  17. Episode 423: 430. Hormone Replacement Therapy and the Black Box Warning

    Let’s rewind to the early 2000s. Flip phones were cool, low-rise jeans were a crime, and the Women’s Health Initiative—WHI—dropped what became the medical equivalent of a headline: “Hormone Therapy Increases Risk!” The study looked at one very specific regimen: an oral pill with conjugated equine...

  18. Episode 422: 429. Rivaroxaban vs Apixaban = The Battle of the Blood Thinners!

    — rivaroxaban versus apixaban. Yes, folks, this is The Battle of the Blood Thinners! And spoiler alert — one of them came out looking like the overachiever in a safety class... while the other probably needs a little extra padding on its report card. The Setup So here’s the story. For years,...

  19. Episode 421: 428. Asthma and Stroke --- A breathless combination

    Minocycline in Acute Ischemic Stroke (EMPHASIS trial) A multicenter, double-blind RCT in China studied 1,724 patients with acute ischemic stroke treated within 72 hours of onset. Patients received either a 4.5-day course of oral minocycline or placebo. Minocycline works by inhibiting microglial...

  20. Episode 420: 427. Kawasaki disease-no, not the motorcycle company

    Today, we're talking about Kawasaki disease-no, not the motorcycle company, though sometimes treating it does feel like trying to ride one at full speed through uncertainty. For decades, high-dose aspirin was basically the holy water of Kawasaki treatment. Eighty to a hundred milligrams per...

  21. Episode 419: 426. Go Big or Go Partial? The Knee Replacement Showdown

    Setting the stage Picture this: your knee is like a three-room apartment. You've got a medial room, a lateral room, and a patellofemoral room. In isolated anteromedial osteoarthritis, just one room is trashed. The rest of the apartment still looks like something you'd put on a rental listing. So...

  22. Episode 418: 425. Triptan initiation and cerebrovascular events

    Kalapura C, et al. Triptan initiation and cerebrovascular events in patients with migraine: A nationwide cohort study. J Am Heart Assoc 2026 Feb 17; 15:e043409. DOI: 10.1161/JAHA.125.043409. Today, we're talking triptans - those long-trusted migraine relievers - and a new study that asks a...

  23. Episode 417: 424. GLP1 and NAION

    Li H-Y, et al. GLP-1 receptor agonists and risk of optic nerve or vision-threatening events in patients with type 2 diabetes or cardiometabolic diseases: A meta-analysis of randomized controlled trials. Diabetes Care 2026 Mar 1; 49:526. DOI: 10.2337/dc25-1929. Heberer K, et al. New-onset...

  24. Episode 416: 423. CME-- Discharge Questions Answered in 2025

    CME-- Discharge Questions Answered in 2025

  25. Episode 415: 422. Finerenone restores fertility?

    Lin Z, et al. Antifibrotic drug finerenone restores fertility in premature ovarian insufficiency. Science 2026 Feb 5; 391:eadz4075. DOI: 10.1126/science.adz4075. Premature ovarian insufficiency is usually one of those diagnoses that shuts the door on fertility: ovarian function is lost before age...

  26. Episode 414: 421. Scabies and DUKE criteria

    Stavropoulou E, et al. Reassessing the 2023 International Society for Cardiovascular Infectious Diseases Duke clinical criteria for infective endocarditis: Impact of excluding fever and updating diagnostic definitions. Clin Infect Dis 2025 Dec 31; [e-pub]. DOI: 10.1093/cid/ciaf737. Big takeaways...

  27. Episode 413: 420. Frail and CODE LVO PLUS antibiotics don't help viral illness

    we look at CODE LVO and what does being frail even mean????? vaccines may not help baby and antibiotics still don't help viral illness

  28. Episode 412: CME song --Check the Lytes

    CME song --Check the Lytes

  29. Episode 411: CME - sodium, potassium, calcium

    CME - sodium, potassium, calcium

  30. Episode 410: 418. Beta Blockers Post MI, PSA, Youtube,

    10.1016/j.jaip.2025.07.005.40675327 All of the videos were found to be useful or very useful, 99% were of moderate or high reliability, and 99% had moderate to excellent educational quality Prostate-specific antigen levels among participants receiving annual testing. JAMA Oncol 2025 Nov; 11:1341...

  31. Episode 409: 417. Aspirin, Pre-diabetes, Menopause, Type 1 Diabetes, HPV Vaccine and more!!!!

    Wolfe R, Broder JC, Zhou Z, et al. Aspirin, cardiovascular events, and major bleeding in older adults: extended follow-up of the ASPREE trial. Eur Heart J. 12 Aug 2025. [Epub ahead of print]. https://pubmed.ncbi.nlm.nih.gov/40796244/ Donocan LE et al. Closed-loop insulin delivery in type 1…

    more

  32. Episode 408: 416. Car Seats, Beta-Blockers after a Heart Attack, Oral Semaglutide, High-Dose influenza vaccine

    Beta-Blockers after Myocardial Infarction without Reduced Ejection Fraction - https://www.nejm.org/doi/full/10.1056/NEJMoa2504735?query=WB McGuire DK et al. Oral semaglutide and cardiovascular outcomes in high-risk type 2 diabetes. N Engl J Med 2025 Mar 29; [e-pub]....

  33. Episode 407: 415. Do Air Filters Lower Blood Pressure?

    https://pubmed.ncbi.nlm.nih.gov/40767818/ This is a great example for students and residents to look and see that the abstract does not always match what the paper actually says

  34. Episode 406: 414. Resistant Hypertension, Physical Therapy, Steroids for Pneumonia

    Efficacy and safety of Baxdrostat in uncontrolled and resistant hypertension compared to placebo in phase three when there are MRA available that are cheap and available A randomised trial of physical therapy for meniscal tear and knee pain discovers that home exercises are just as good as…

    more

  35. Episode 405: 413. 4 Articles to Scare You-- COPD, Cirrhosis, ETOH, and Ablation

    gabapentin may increase COPD exacerbations Benzo for ETOH might be long gone..guess what is going to replace it Anticoagulation after ablation.... what do you do with it? BBlocker in those with cirrhosis and varices

  36. Episode 404: 412. Liver Transplant - The One Referral I Doubt You Are Doing Correctly

    Clinicians should refer patients for liver transplant evaluation after any decompensation event—such as ascites or variceal bleeding—regardless of MELD score. After a first decompensation, 5-year mortality is 20–30%; after a second, it rises to 80–90%. Refractory ascites carries a 50% 1-year...

  37. Episode 403: 411. Gabapentin and Emergency Carotid Artery Stenting in Stroke

    Study Summary: Emergent Carotid Stenting in Acute Stroke Thrombectomy A multicenter registry study in Catalonia (2017–2023) evaluated outcomes in 578 patients with acute ischemic stroke and tandem lesions (large-vessel occlusion plus extracranial carotid stenosis). Patients were divided into two...

  38. Episode 402: 410. When You Shouldn't Double Down But Instead Hit for Another

    This massive meta-analysis of 484 randomized, double-blind, placebo-controlled trials (104,176 participants) quantified the blood pressure–lowering effects of major antihypertensive drug classes and their combinations. It introduces a new intensity-based classification system and an online...

  39. Episode 401: 409. The Effects of Upper Extremity and Lower Extremity Aerobic Exercise Training in Patients with Peripheral Arterial Disease:

    Practice Pearls: “Skip Leg Day” (Sometimes) For PAD patients who can’t tolerate leg workouts, upper body aerobic training is a strong, evidence-backed alternative. It’s not just a workaround—it’s a workout. Citation Ahiskali GN, Demirel A, Yamikan H, Kutukcu EC. The Effects of Upper Extremity and...

  40. Episode 400: 408. CME Obesity and MASH

    GLP1 drugs work but they likely need lifestyle modifications No convincing evidence GLP1 cause thyroid cancer in humans BUT contraindication if family history exist Stopping therapy usually results in weight gain Insurance coverage for weight loss is limited and variable Semaglutide for type 2...

  41. Episode 399: 407. OMED COPD CME

    OMED COPD CME

  42. Episode 398: 406. Update of Medical Articles

    All of these articles have been talked about on questioning medicine social media on tik tok and instagram but here is an update of my recent reading

  43. Episode 397: 405. 4 New Medical Articles That Are Deceiving

    Buelt, Andrew | 2:13 PM (1 hour ago) | | to me https://jamanetwork.com/journals/jama/fullarticle/2833338 Conclusions and Relevance These results support use of metformin for treatment of symptomatic knee osteoarthritis in people with overweight or obesity. Because of the modest sample size,...

  44. Episode 396: 404. albuterol/budesonide, DOAC in 4 Days, Statins for AAA

    https://www.nejm.org/doi/10.1056/NEJMoa2504544 During follow-up ranging from 12 to 52 weeks, fewer patients had severe exacerbations in the albuterol/budesonide group than in the albuterol group (5% vs. 9%). Patients in the albuterol/budesonide group had less than half the total exposure to...

  45. Episode 395: 403. COVID Maternal Booster And Cervical Self Swabs

    https://publications.aap.org/pediatrics/article/156/1/e2024070175/202234/Infant-Antibodies-After-Maternal-COVID-19?autologincheck=redirected Objective: The study aimed to evaluate the kinetics and duration of maternally derived antibodies in infants up to 6 months old, following maternal COVID-19...

  46. Episode 394: 402. Cardiovascular Risk Factors, Zilebesiran, Shared Decision Making

    https://www.nejm.org/doi/10.1056/NEJMoa2415879?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed Key Findings: Classic Risk Factors: The five risk factors examined were hypertension, hyperlipidemia, underweight and overweight or obesity, diabetes, and smoking. These...

  47. Episode 393: 404. 3 quick articles you might want to know about (oral semaglutide, tiktok, and GLP1 thyroid cancer)

    GLP1 might cause thyroid cancer in mice but the evidence is drastically lacking in humans Oral semaglutide is expensive for an NNT of 50 at 4 yrs Tiktok videos of skin care are a scam

  48. Episode 392: 403. 3 Papers, 1 Podcast - One Guideline Changer

    https://jamanetwork.com/journals/jama/article-abstract/2834040 amiloride is realistically equal to spironolactone for resistant HTN https://journals.lww.com/ajg/abstract/2025/05000/higher_rate_of_spontaneous_bacterial_peritonitis.24.aspx prophalaxis antibiotics might not be needed...

  49. Episode 391: 402. Functional disability after clinically significant extracranial bleeding: a secondary analysis of ASPREE

    https://www.jthjournal.org/article/S1538-7836(25)00109-6/fulltext Antithrombotic agents, like aspirin and anticoagulants, are essential for treating many cardiovascular conditions. However, a common side effect is bleeding, with extracranial bleeding—bleeding outside the brain and spinal…

    more

  50. Episode 390: 401. Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension

    https://jamanetwork.com/journals/jama/article-abstract/2834632 Summary The article examines the effectiveness and safety of zilebesiran, an RNA interference therapeutic agent, when used in combination with standard first-line antihypertensive drugs for patients with inadequately controlled...

View all 400 episodes →

Type above to search every episode's transcript for a word or phrase. Matches are scoped to this podcast.

Searching…

We're indexing this podcast's transcripts for the first time — this can take a minute or two. We'll show results as soon as they're ready.

No matches for "" in this podcast's transcripts.

Showing of matches

No topics indexed yet for this podcast.

Loading reviews...

ABOUT THIS SHOW

Join Andrew on a medical rollercoaster as we ask a medical question and answer it based on recent published papers.

HOSTED BY

Questioning Medicine

CATEGORIES

health fitness medicine

Frequently Asked Questions

How many episodes does Questioning Medicine have?

Questioning Medicine currently has 400 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.

What is Questioning Medicine about?

Join Andrew on a medical rollercoaster as we ask a medical question and answer it based on recent published papers.

How often does Questioning Medicine release new episodes?

Questioning Medicine publishes regularly with 400 episodes available. Check the episode list for the typical release schedule.

Where can I listen to Questioning Medicine?

You can listen to Questioning Medicine on PodParley by clicking any episode. We provide an embedded audio player for direct listening, and you can also subscribe via your preferred podcast app using the RSS feed.

Who hosts Questioning Medicine?

Questioning Medicine is created and hosted by Questioning Medicine.
URL copied to clipboard!