Stronger by Design for Women with Michelle MacDonald

What if the menopause industry isn't failing women but instead  it's deliberately targeting them?Michelle MacDonald sits down with scientist, physician, and Selfority founder Dr. Sarah Berg for a conversation that pulls back the curtain on how a $15 trillion industry is built on the gap between what women need and what medicine has historically given them. Together they unpack why midlife women have become the most targeted consumer demographic in wellness, how the "natural" hormone narrative that exploded after the 2002 WHI study opened the door for an entire compounding market, and why so many women are making major health decisions at 3am while sleep deprived and algorithmically cornered. They also dig into the science of the placebo effect including why supplement companies deliberately build their packaging around the same 4 to 8 week window that research shows produces maximum placebo response and what it means to advocate for yourself in a space designed to exploit your vulnerability. This is an episode for every woman who has ever wanted to optimize her health and found herself wondering whether she's being helped or just sold to.Favorite Moments1:35 Why Women Over 50 Are a $15 Trillion Target3:21 The Group Text Is the New MLM7:41 How the 2002 Hormone Scare Built the Compounding Market9:42 Bioidentical Hormones: What the Word Actually Means13:34 The Placebo Study That Should Make You Rethink Every Supplement You've Bought15:27 Why Supplement Packaging Says "Wait 4 to 8 Weeks" and It's Not an Accident17:38 The 2002 Sham Knee Surgery That Proves the Brain Is the Most Powerful Drug We Have24:44 The DUTCH Test: What It Is, What It Can't Do, and Why It Often Leads to a Supplement Stack29:38 Drunk Buying at 3am: Sleep Deprivation, Algorithms, and the Menopause Marketing Machine35:32 Why Your Jeans Stopped Fitting - The Estrogen & Visceral Fat Connection41:36 Skinny Check vs. Frailty Check: The Reframe Women Actually Need46:34 What's Coming: The $24 Billion Menopause Research Bill and Medical School Curriculum Change"They're taking it because they're getting humbled relentlessly by the story that their bodies are broken. And so they're not even looking at the big levers." ~ Dr. Sarah BergGUEST: DR. SARAH BERGFounder, Selfority | Principal Scientist, Unbiased ScienceInstagram: https://www.instagram.com/selfority/Website: https://www.selfority.com/Dr. Sarah Berg is a physician-scientist and fierce advocate for evidence-based communication in women's health. As a Principal Scientist with the Unbiased Science team, she brings clinical expertise and a sharp eye for predatory marketing to one of the most underserved areas in medicine. Through Selfority - a name she built to say "self priority" out loud - she is on a mission to make sure women have the information they actually need to make informed decisions about their health, not just the information someone is trying to sell them.About Michelle:Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.==========================================================If this conversation gave you something to think about, subscribe so you never miss an episode. New conversations drop regularly, all built around the same goal: giving you the tools to take your health and performance seriously, for the long term.==========================================================Stronger by Design Podcast🎙️ Spotify: https://open.spotify.com/show/7uljSBX7oSNQWhDVutk29m🎙️ Apple Podcasts: https://podcasts.apple.com/us/podcast/stronger-by-design-for-women-with-michelle-macdonald/id1677831398==========================================================Connect with Michelle:📸 Instagram: https://www.instagram.com/michellemacdonaldofficial/📘 Facebook: https://www.facebook.com/michelle.macdonald.yhhedonista▶️ YouTube: https://www.youtube.com/@michellemacdonaldofficial🔗 Website: https://www.michellemacdonaldofficial.com/

What if the peptide your favorite influencer is swearing by has never once been tested in a human clinical trial?Michelle MacDonald sits down with drug development scientist Leigh Baxt, PhD  for a conversation that cuts straight through the wellness peptide industry.Together they break down how drugs actually make it from an idea to FDA approval, why 99% of them never do, and what it means that the peptides flooding your social media feed are, in most cases, sitting at the very earliest stage of that process with almost no human data behind them. This episode digs deep into BPC-157 specifically, examining why the science raises serious red flags, and what informed consent actually sounds like when a clinician is promoting something with this little evidence. This information is essential listening for women who want to take charge of their health, cut through the marketing noise and make truly informed decisions.Favorite Moments1:57 The Staggering Failure Rates Behind Every Drug You've Ever Taken3:07 From Idea to FDA Approval: What the Process Actually Looks Like5:28 BPC-157: Why the Red Flags Are Hard to Ignore12:49 Stacking Peptides & the Drug Interaction Problem Nobody Talks About16:30 When Clinicians Become Marketers22:21 How to Use ClinicalTrials.gov to Check the Evidence Yourself28:22 The Patent Myth That Peptide Promoters Keep Repeating"I want people to be informed. I want them to understand what data does and doesn't exist. Most importantly, I want them to be able to differentiate data from marketing — because even the most seasoned scientists can get sucked in." — Leigh Baxt, PhDGUEST: LEIGH BAXT, PhD - DRUG DEVELOPMENT SCIENTISTInstagram | LinkedInLeigh works in early-stage preclinical drug development, the phase where 90% of ideas fail before they ever reach a human. Her work focuses on understanding whether promising biological mechanisms can actually be turned into safe, effective therapeutics. She volunteers her expertise with the Unbiased Science team to help the public understand how medicines are made, why the vetting process matters, and how to tell the difference between data and marketing.CONNECT WITH MICHELLEWebsite | Instagram | YouTube | Facebook | XAbout Michelle:Michelle MacDonald is the creator of the FITNESS MODEL BLUEPRINT™ and host of the Stronger By Design™ podcast. Known globally for her transformation programs, Michelle empowers women to redefine aging through evidence-based strength training, nutrition, and mindset practices. Since 2012, she has coached thousands of women online, leveraging her expertise as a Physique Champion and ISSA Strength and Conditioning Specialist. She co-founded Tulum Strength Club and established The Wonder Women (TWW), inspiring countless transformations including her mother, Joan MacDonald (Train With Joan™). Michelle continues to lead the charge in women's fitness, launching the Stronger by Design™ fitness app in fall 2024.Where to Watch/Listen:Website Apple Podcasts Spotify YouTubeLeave a rating for this podcast with one click.Nothing in this video or podcast constitutes medical advice. Always consult a qualified healthcare professional before making changes to your health or fitness routine.