The Chemist Couple Podcast

Welcome to The Chemist Couple Podcast! In today’s episode, we’re diving into the Top 5 Health Trends for 2025 that are reshaping how we approach health and wellness. If you’re actively working to improve your health, listening to these trends is essential for your wellness journey. We explore: * Gut Microbiome: Find out how the health of your gut is directly linked to overall wellness, immunity, and mental health. * Mental Wellness & Mindfulness: Learn about practices to improve mental clarity, reduce stress, and enhance emotional well-being. * Sustainable Healthcare: Explore eco-friendly and sustainable practices in modern medicine and healthcare systems. * Personalised Nutrition: Discover how tailored nutrition plans are helping individuals optimise their health. * Digital Health Trackers: Understand how health tech devices and wearables can track and improve your fitness and wellness goals. Whether you're looking to boost physical health, improve mental clarity, or stay ahead with the latest wellness technology, this episode has the insights you need for 2025. 🔔 Subscribe now for more expert tips on health trends, wellness, nutrition, and mindfulness! #HealthTrends2025 #GutMicrobiome #MentalWellness #HealthTech #PersonalisedNutrition If you would like to go to a particular section, please click on the time stamp below: 00:00 Introduction 00:35 - Health Trend 1 - The Gut Microbiome 15:57 - Health Trend 2 - Mental Wellness and Mindfulness 28:44 - Health Trend 3 - Sustainable Self Care 32:17 - Health Trend 4 - Personalised Nutrition 36:09 - Health Trend 5 - Digital Health Trackers 41:32 - Our Rankings of Health Trends 49:06 - Final Thoughts Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: * https://pmc.ncbi.nlm.nih.gov/articles/PMC8935176/ - Journaling evidence * https://pmc.ncbi.nlm.nih.gov/articles/PMC5374271/#sec36 - Accuracy of wearable devices in physical activity * https://pmc.ncbi.nlm.nih.gov/articles/PMC8817215/ - Systematic review- Accuracy & acceptability of wearable devices * https://www.thelancet.com/journals/landig/article/PIIS2589-7500(22)00111-X/fulltext - Wearable devices and their effects on physical health * https://pmc.ncbi.nlm.nih.gov/articles/PMC11399740/ - Accuracy for detecting medical conditions * https://pmc.ncbi.nlm.nih.gov/articles/PMC10757793/#sec4- Apple Watch v 12 lead ECG * https://www.nature.com/articles/s41598-019-44097-3 - Effect of spending time in nature * https://pubmed.ncbi.nlm.nih.gov/29795809/ - ‘The American Gut project’ * https://www.nature.com/articles/s41575-024-00893-5 - UPF and food additives on gut health * https://www.mdpi.com/2072-6643/11/8/1806 - Consumption of fermented foods on gut health * https://www.bmj.com/content/361/bmj.k2179 - role of the gut microbiome on nutrition and health * https://pmc.ncbi.nlm.nih.gov/articles/PMC5082693/ - Dysbiosis of the gut microbiome on the increase prevalence of obesity * https://pmc.ncbi.nlm.nih.gov/articles/PMC7700621/ - how your diet effects your gut microbiome * https://www.who.int/news/item/17-06-2022-who-highlights-urgent-need-to-transform-mental-health-and-mental-health-care - World Health Organisation on need to transform mental health * https://pmc.ncbi.nlm.nih.gov/articles/PMC8651630/ - Sleep and its impact on mental health

Welcome back to our podcast, in this episode we discuss the multi-billion dollar sector that is supplementation. Key topics are whether you need a multivitamin within your diet, how the supplement industry is regulated and our stance on the future of supplementation. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:00 - Introduction 00:37 - Why are we discussing multivitamins 01:05 - What is the definition of a vitamin? 02:18 - Regulatory bodies in the UK and USA - MHRA/ FDA 02:53 - What are the rules and regulations surrounding vitamins/ supplements? 10:58 - Does the lack of regulations on these products impact their quality? 13:00 - Why do we take vitamins in the first place? 14:20 - Study that found increased risk of mortality in those taking multivitamins 17:03 - Do we personally take any multivitamins? 19:42 - Bioniq - the personalised supplement company 22:32 - Where did the RDA guidelines come from and are they still relevant today? 22:50 - Why the supplement industry makes the idea of taking vitamins/ supplements so convincing 29:03 - Is there any evidence to suggest that taking vitamin supplements has an impact on preventing chronic diseases? 29:23 - Is taking a vitamin supplement as effective as getting our vitamins from whole food sources? 30:55 - Summary of key points Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://assets.publishing.service.gov.uk/media/5a7b8297e5274a7318b8f20d/Supplements_Summary__Jan_2012__DH_FINAL.doc.pdf - Department of Health- legislation https://www.food.gov.uk/business-guidance/food-supplements#what-a-food-supplement-is - food standards agency https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14521#:~:text=Individuals%20who%20want%20to%20improve,provisions%20of%20general%20food%20law - British Journal of Pharmacology- vitamin D quality review https://pmc.ncbi.nlm.nih.gov/articles/PMC11208972/#abstract1 - US Cohort multi-vitamin daily use study https://pmc.ncbi.nlm.nih.gov/articles/PMC5998735/ - History of nutrition https://pmc.ncbi.nlm.nih.gov/articles/PMC9174310/#Sec4 - The effect of the food matrix https://pmc.ncbi.nlm.nih.gov/articles/PMC6743828/#sec1 - Dairy food and matrix https://jamanetwork.com/journals/jama/fullarticle/195038 - vitamins for chronic disease prevention https://pmc.ncbi.nlm.nih.gov/articles/PMC2125921/ - dietary selenium use in production Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

Welcome back to our podcast, in this episode we discuss the rising rates of colon cancer in the under 50s. By 2030 colon cancer is expected to be the leading cause of cancer-related deaths in this age group. We explore how we can get screened, the signs and symptoms to look out for and discuss the possible causes of these shocking statistics. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:00 - Introduction 00:47 - Why are we discussing colon cancer rates in young people? 01:55 - Colon cancer vs Bowel cancer - different terminologies USA vs UK 02:10 - Colon cancer statistics 02:42 - Should we be worried about getting colon cancer less than 50 years 06:44 - Limitations to current evidence 08:00 - National bowel screening programmes - USA and UK 12:43 - Signs and symptoms of colon cancer 14:39 - Risk factors for developing colon cancer 15:51 - Does the gut microbiome play a role in the development of early onset colon cancer 18:28 - Importance of maintaining healthy BMI on the development of early onset colon cancer 20:06 - correlation between western diet, UPF on non communicable diseases and colon cancer 22:40 - What should our governments be doing to address this? 25:37 - Summary of key points in podcast Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://www.mdpi.com/2072-6694/13/23/5933 - The role of diet and lifestyle on early onset colon cancer https://pmc.ncbi.nlm.nih.gov/articles/PMC6957737/ - Influence of the gut microbiome, diet and environment on risk of colorectal cancer https://pmc.ncbi.nlm.nih.gov/articles/PMC9745098/#s12 - Fusobacterium nucleatum and colorectal cancer: from phenomenon to mechanism https://www.mdpi.com/2072-6694/13/23/5933 - factors in early onset colon cancer https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045%2824%2900600-4/fulltext - rising colon cancer in young adults Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

Welcome back to our podcast, in this episode we discuss how we are going to act upon our ApoB results that we shared previously. We aim to apply the current studies to our lifestyle and measure how effective our interventions have been in 3-4 months. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 02:35 - How is the microbiome involved in cholesterol metabolism? 03:23- Coprostanol and its role in cholesterol homeostasis 04:27 - Cholesterol entrapment via gut bacteria 05:43 - Secondary bile acids produced by the gut microbiome 08:08 - The importance of a diverse gut microbiome 12:56 - How to increase your plant intake 14:14 - importance of probiotic for gut microbiome diversity 14:40 - prebiotics and the microbiome 15:09 - Can alcohol theoretically decrease the diversity of the gut microbiome? 16:14 - Is it easy for people with IBS to improve their gut microbiome? 18:18 - Fasting window and gut health 19:14 - antibiotic use and the impact on the gut microbiome 21:25 - does decreasing saturated fats in your diet have a direct effect on cholesterol/ APOB levels 24:18 - Impact of exercise on CVD risk, APOB and LDL-C 25:05 - how energy is used during different intensities of exercise - VO2max 31:03 - dietary carbohydrate consumption and its role in CVD risk 36:28 - Summary - what are we going to be doing going forward to improve our biomarkers? 41:05 - outro Here are our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://pmc.ncbi.nlm.nih.gov/articles/PMC4242964/#:~:text=Recently%2C%20regular%20exercise%20has%20been,apoA1%20ratio%20demonstrated%20significant%20interactions - exercise in overweight women on ApoB https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1365-2796.2007.01806.x - exercise on ApoB- predominantly males https://pmc.ncbi.nlm.nih.gov/articles/PMC5972657/#sec4 - saturated fats on ApoB https://pmc.ncbi.nlm.nih.gov/articles/PMC7468809/#sec1-nutrients-12-02204 - Glycaemic index & load on lipid kinetics https://www.ahajournals.org/doi/10.1161/ATVBAHA.120.315766#graphical-abstract - Saturated fats increasing atherogenicity of LDL-c https://pmc.ncbi.nlm.nih.gov/articles/PMC7416843/ - gut microbiome & CVD https://pmc.ncbi.nlm.nih.gov/articles/PMC7049528/ - high fibre diets on short chain fatty acids https://pmc.ncbi.nlm.nih.gov/articles/PMC7230435/ - Gut microbiome & intestinal permeability Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Links to cardiac screening - North West, UK https://www.timcogleyfoundation.com https://healthchecks.randoxhealth.com/tim-cogley-foundation

Welcome back to our podcast, in this episode we discuss our recent cardiac screening results. Cardiovascular disease is still the biggest killer worldwide and so being able to interpret our blood results and calculating our individual risk is important in order to help prevent progression in the future. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 01:40 - LDL-C and its role in cardiovascular risk 02:14 - LDL-C: What our results were and what should we be aiming for? 02:50 - Why you shouldn’t use results in isolation | Area under the curve 04:00 - Significance of family history on cardiovascular disease risk 06:50 - Is ApoB a superior biomarker for measuring cardiovascular disease risk? 10:00 - Interpreting ApoB results | Should we be more aggressive in treating ApoB levels? 17:16 - Balancing health anxiety with being health conscious 18:53 - Interpretation of BMI | BMI limitations 24:52 - Where did we get our cardiac screening test done? | Tim Cogley Foundation 26:06 - Metabolic age v chronological age | How accurate is this test? 27:40 - Why we should know our own health on a deeper level 28:26 - Fasting blood glucose; our results 30:12 - Advocating prevention of long term health conditions, but emphasising the importance of pharmacological therapy when it is needed 33:55 - Cardiovascular risk score 38:05 - upcoming podcast episodes | Summary Here is our podcast links: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA https://podcasts.apple.com/us/podcast/the-chemist-couple-podcast/id1773332678 Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://pmc.ncbi.nlm.nih.gov/articles/PMC10693914/#:~:text=BMI%20was%20originally%20established%20in,benefits%20%5B1%2C2%5D - BMI review in clinical practice https://www.lipidcenter.com/pdf/Framingham.pdf - ApoB percentile chart https://pmc.ncbi.nlm.nih.gov/articles/PMC7369156/ - Overview of ApoB https://www.ahajournals.org/doi/10.1161/JAHA.122.025858 - ApoB physiology Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Links to cardiac screening - North West, UK https://www.timcogleyfoundation.com https://healthchecks.randoxhealth.com/tim-cogley-foundation

Welcome back to our podcast, in this episode we discuss how you should be exercising and we feel this very appropriate coming up to the New Year’s resolutions. We give our insight on what is working for us currently and debunk a lot of myths that people may be presented with when starting their exercise journey. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 00:38 - What did Jess used to do for exercise? 02:26 - Did HIIT training work for Jess? 03:00- What did Lee used to do for exercise? 05:08 - What training is working for Jess at the moment? 07:45 - Are current training regimens over complicated? 09:20 - Hyrox, get involved or get rid? 10:28- Should you focus on your weaknesses in exercise? 11:45 - 1% improvements will result in the greatest successes 12:47 - consistency is key 13:30 - Why do we exercise and why should you exercise? 16:30 - How should you start exercising? 19:04 - What is the evidence for exercise being of benefit? 20:32 - Find your purpose for exercising 21:58 - What are we going to implement in your training going forward? 25:40 - Final thoughts 28:52 - What is our next episode? Here is our podcast link: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://www.who.int/news-room/fact-sheets/detail/falls - falls stats from WHO 2021 https://assets.publishing.service.gov.uk/media/641d9957ba5ac9000cb1a838/CMOs-physical-activity-guidelines-appendices-march-2023.pdf - CMO UK’s activity guidelines https://www.amjmed.com/article/s0002-9343(14)00138-7/fulltext - muscle mass with longevity Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

Welcome back to our podcast, in this episode we discuss if counting calories is helpful in achieving our health goals. We talk through both the benefits of counting calories but also the potential pitfalls of this popular ‘diet’. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 01:19 - What is a calorie? 02:01 - Food is more than just calories 02:42 - Why did Jess count calories? 04:05 - Where there more benefits for Jess counting calories? 06:08- Has calorie counting created a negative relationship with Jess’s food habits? 08:30 - What are the benefits to calorie counting? 10:16 - What are the negatives to calorie counting? 11:48 - Are calculated calories accurate? 15:15 - Do we count calories for health or aesthetics? 17:15 - Does calorie counting have longevity? 18:25 - Social media’s ‘healthy meal alternative’ trend 20:15 - What should you do if you currently count calories? 23:25 - Do you now look at food differently? 24:50 - How do you deal with not focussing on calories? 26:01 - What is our overall opinion on calorie counting? 30:25 - Can you bank calories? 32:05 - Summary Here is our podcast link: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA Sign up to our newsletter and stay up to date with how we personally apply the science to enhance our lifestyle: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://pmc.ncbi.nlm.nih.gov/articles/PMC3396444/#bib2 https://pmc.ncbi.nlm.nih.gov/articles/PMC7946062/ https://pmc.ncbi.nlm.nih.gov/articles/PMC3405064/ https://www.gov.uk/government/publications/calorie-labelling-in-the-out-of-home-sector/calorie-labelling-in-the-out-of-home-sector-implementation-guidance Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

Welcome back to our podcast and to a question which many want a clear answer to, does dietary cholesterol increase cardio vascular risk? Honestly, the evidence is a hard read and we invite you to listen to our opinions and more importantly, how are we going to implement the studies. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:03 - Introduction 01:30 - Did you think dietary cholesterol increases serum levels? 02:43 - Why are eggs used in cholesterol studies? 03:55 - What are the current guidelines for cholesterol consumption? 05:00 - Does dietary cholesterol increase serum cholesterol? 09:16- How much dietary cholesterol do we absorb? 10:50 - Why do we have LDL cholesterol, an evolutionary trait? 13:24 - What foods are high in dietary cholesterol? 13:52 - Does saturated fat have a role to play in serum cholesterol? 17:50 - How do genetics play a part in serum cholesterol levels? 18:23 - Are we treating serum cholesterol appropriately? 19:09 - Does the gut microbiome play a role in serum cholesterol? 22:56 - What are we going to do with our diet? 27:32 - What to expect in upcoming podcasts Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://www.jacc.org/doi/10.1016/j.jacc.2020.05.077 https://pmc.ncbi.nlm.nih.gov/articles/PMC9143438/#sec2-nutrients-14-02168 https://www.jlr.org/article/S0022-2275(20)33370-8/fulltext https://www.ahajournals.org/doi/10.1161/CIR.0000000000000743 https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-019-0715-8#Sec25 https://pmc.ncbi.nlm.nih.gov/articles/PMC6024687/#notes2 https://www.cambridge.org/core/journals/nutrition-research-reviews/article/nutritional-management-of-hyperapob/FF922E54AB1189F1AF2194888D99DA0F https://www.jlr.org/article/S0022-2275(20)33152-7/fulltext Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Randox link: https://www.timcogleyfoundation.com/cardiac-screening/

Welcome back to our podcast and the beginning of a mini series on cholesterol, arguably the most understood aspect of physical health. We touch upon the importance of cholesterol, the discrepancies in nomenclature surrounding cholesterol, why we should be aware of our cholesterol physiology and what we are doing from a personal point of view. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:07 - Why should we be measuring cholesterol? 03:19 - Why is cholesterol important? 04:08 - Why we can’t say cholesterol is good or bad? 07:04 - Do we take our cholesterol results seriously? 09:57 - What is apoB? 11:14 - What is coming up in this lipid mini series? Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: Guyton & Hall Medical Physiology 14th edition- general physiology overview Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Randox link: https://www.timcogleyfoundation.com/cardiac-screening/

Welcome to our discussion on GLP-1 medication in the context of their weight loss licensing. All medication comes with risk, but as this class of medication has many benefits, including aesthetics, we believe many people have lost touch with the fact that these are regulated medication. We have became aware of online communities providing medical advice for GLP-1 medication, this is highly dangerous and this should not be a primary source of information and should be discussed with your healthcare team. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below (please note this podcast was extremely hard to time stamp, so we did our best): 00:08 - Why are we discussing GLP-1 medications again? 01:54 - Online weight-loss communities are more detrimental than good 09:58 - How is medication regulated in the UK? 16:32 - Are online pharmacies helping the situation? 20:34 - GLP-1 medication does require you to adopt a healthy lifestyle 21:58 - The controversial aspects of health? 28:52 - Social media versus health care professionals 29:58 - Let’s discuss ‘Big Pharma’ 33:08 - Our final thoughts and key points Here is our podcast link: https://open.spotify.com/show/5kJoyk0uY8u1H8CmgNDWzo?si=JF4_mY8oSES520KcOaHwhA Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://www.nejm.org/doi/full/10.1056/NEJMoa2206038 https://www.nejm.org/doi/full/10.1056/NEJMoa1411892 https://www.nejm.org/doi/10.1056/NEJMoa2032183?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed Rang & Dale’s Pharmacology 10th edition - general pharmacological overview

Welcome to the final episode of this alcohol series, this week we discuss the interactions of alcohol with common medication that you may encounter. As always, our aim is to provide the evidence for you to decide whether alcohol should be apart of your lifestyle and we do so in an unbiased fashion. Within this episode we assess the evidence relating to the proposed mechanism of interactions, proposed outcome and what this means in a practical sense. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:07 - Welcome back 00:54 - What did we think of alcohol with medication? 02:12 - How can drugs interact with each other? 02:58 - How can alcohol interact with commonly bought medication? 09:27 - How does alcohol interact with drugs that act on the CNS? 12:37 - What should I be cautious of when taking alcohol with anti-microbial medication? 16:39 - How does alcohol interfere with drugs that work on the cardiovascular system? 18:58 - Alcohol and diabetic medication interaction? 20:07 - Key points to note about alcohol with medication 20:51 - Final thoughts Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://pmc.ncbi.nlm.nih.gov/articles/PMC4498995/#:~:text=Glucuronidation%20is%20the%20main%20pathway,detoxified%20by%20the%20glutathione%20pathway https://pmc.ncbi.nlm.nih.gov/articles/PMC7038249/#:~:text=Available%20data%20support%20that%20oral,are%20equivocal%20for%20trimethoprim%2Dsulfamethoxazole Rang & Dale’s Pharmacology 10th edition - general pharmacological overview https://www.alcoholics-anonymous.org.uk/ - Alcoholic anonymous

Welcome to the 3rd episode of our alcohol series, this week we discuss the perceived benefits of alcohol for our health. As always, our aim is to provide the evidence for you to decide whether alcohol should be apart of your lifestyle and we do so in an unbiased fashion. Within this episode we assess the evidence relating to cardiovascular health, social implications and current uses in therapeutic medicine. There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:07 - What were our initial instincts surrounding alcohol benefits? 04:15 - What are the uses of alcohol? 05:36 - Social benefits of alcohol, what is the evidence? 11:44 - Is alcohol beneficial for your cardiovascular health? 19:30 - Do we agree to alcohol having any benefit? 23:25 - Alcohol use in medicinal formulations 26:25 - Our final opinion and thoughts on alcohol Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Here is a list of the sources that we used to make this podcast: https://link.springer.com/article/10.1007/s40750-016-0058-4 https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-023-02911 w#:~:text=The%20“J%2Dshaped”%20relationship,it%20greatly%20increases%20health%20risks. https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-023-02907-6 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2802963 https://www.ncbi.nlm.nih.gov/books/NBK556147/ https://www.ema.europa.eu/en/documents/scientific-guideline/information-package-leaflet-regarding-ethanol-used-excipient-medicinal-products-human-use_en.pdf https://www.bmj.com/content/363/bmj.k4370/rr-2 https://www.sciencedirect.com/science/article/abs/pii/S0378517324001273 https://onlinelibrary.wiley.com/doi/pdf/10.1046/j.1360-0443.1996.911255.x#:~:text=The%20British%20Medical%20Association%20recently,sensible%20drinking%2C%20obtainable%20from%20British Rang & Dale’s Pharmacology 10th edition - general pharmacological overview https://www.alcoholics-anonymous.org.uk/ - Alcoholic anonymous

Welcome to the 2nd episode of our alcohol series, this week we discuss both the acute and chronic complications cited with regular consumption. As always, our aim is to provide the evidence for you to decide whether alcohol should be apart of your lifestyle and we do so in an unbiased fashion. Within this episode we assess the evidence relating to cognitive impairment, alcohol-associated liver disease, use of alcohol in pregnancy, the effect on the microbiome and whether there is still a stigma surrounding alcohol? There is a lot to discuss and we are aware that we cannot cover everything in this episode, also, please see our references below for any further reading. If you would like to go to a particular section, please click on the time stamp below: 00:07 - Introduction & alcohol statistics 03:10 - Acute complications of alcohol 09:12 - Where did the ‘hangover’ originate? 11:30 - Does alcohol increase cognitive impairment? 15:26 - What is Wernicke’s encephalopathy? 17:24 - How is the liver affected by the alcoholic onslaught? 20:41 - Does alcohol impact the microbiome? 22:04 - What are the complications of cirrhosis? 25:25 - Is there still a stigma around alcohol? 28:37 - Our survey says we want to socially drink! 30:46 - Fetal alcoholic syndrome, the risks around pregnancy 32:46 - Alcoholic complications key points 36:16 - Respect people’s choice not to drink 37:46 - Final thoughts Here is a list of the sources that we used to make this podcast: https://www.bmj.com/content/357/bmj.j2353?ijkey=78857d459765a35099284fe4b337607a4a8981f2&keytype2=tf_ipsecsha- cognitive impairment https://www.bmj.com/content/383/bmj-2023-077090 - Alcohol associated liver disease; microbiome dysfunction and general overview https://www.gov.uk/government/statistics/reported-road-casualties-in-great-britain-involving-illegal-alcohol-levels-2021/reported-road-casualties-in-great-britain-involving-illegal-alcohol-levels-2021 - drink driving statistics https://alcoholchange.org.uk/alcohol-facts/fact-sheets/alcohol-statistics?gad_source=1&gclid=CjwKCAjwjsi4BhB5EiwAFAL0YDoiCx0W2Nj8pRbtf-mhAt4awwbUTtlq1DhmDeacEfzrB5oeH3LWExoCo7IQAvD_BwE- general alcohol statistics https://jech.bmj.com/content/68/6/542 - pregnancy study Rang & Dale’s Pharmacology 10th edition - general pharmacological overview https://www.alcoholics-anonymous.org.uk/ - Alcoholic anonymous Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening!

This episode is the start of a 4 part series, researching the origins of alcohol, the physiology, complications, benefits and interference with other medication. Our aim is to provide the evidence, for you to decide whether alcohol should be apart of your lifestyle and we do so in an unbiased fashion. Within this episode we venture into when alcohol was first referenced, what is the current recommended guidelines, how alcohol exerts its effects, what processes does the body possess to cope with alcohol consumption, are there any social implications with alcohol and our personal experiences. If you would like to go to a particular section, please click on the time stamp below: 00:00 - Introduction & Why did we pick alcohol as a topic? 02:16 - What is the history of alcohol? 11:11 - What is a unit of alcohol? What are the current alcohol guidelines? 14:46 - How does our body deal with alcohol and how does alcohol exert its effects? 24:36 - What is our experience of alcohol? What are the social pressures? 30:36 - Final thoughts Here is a list of the sources that we used to make this podcast: https://assets.publishing.service.gov.uk/media/5a80b7ed40f0b623026951db/UK_CMOs__report.pdf - low risk drinking guidelines https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671803/ - molecular action of alcohol https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527027/ - metabolism of alcohol Rang & Dale’s Pharmacology 10th edition - general pharmacological overview Sign up to our newsletter: https://mailchi.mp/c15c44eee6a0/thechemistcouplepodcast You can also watch this podcast episode on YouTube:  https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening!

Type 2 diabetes was once believed to be a lifelong condition, however, evidence now suggests that we can put this into remission. In this episode, we focus on how diet and exercise can have the biggest impact, an area of management that was quickly glazed over in the past. Also, we explain the current pharmacological guidelines, advise on circumstances to monitor whilst taking the medication and offer some personal insight. As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and please subscribe for future episodes, thanks for listening! You can skip to the relevant sections if needed: (00:00-01:15) - Introduction (01:16-27:57) - Diet & lifestyle (27:57-47:26) - Medication (47:27-48:48) - Final Thoughts For this episode we reviewed NICE guidelines, the manufacturer's summary of product characteristics (for each medication) and Rang & Dale's pharmacology. We also discussed the findings of the DiRECT: https://www.thelancet.com/action/showPdf?pii=S2213-8587%2823%2900385-6 You can also watch this podcast episode on YouTube:  https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q

In this episode we discuss type 2 diabetes, how it is diagnosed? What are the complications? What is the prevalence? Just to name a few questions. In our opinion, the severity of diabetes has been diluted, could this be to the high rate of diagnosis in the UK? Nevertheless, we want to emphasise the complications associated with poor diabetic control and if you tune in to next week, we will discuss the current management protocol. You can skip to the relevant sections if needed: (00:00-05:05) - Introduction (05:06-07:05) - Prevalence (07:06-12:36) - Background (12:37-19:20) - Causes/Risk Factors (19:21-20:54) - Prognosis (20:55-27:48) - Complications (27:49-30:35) - Symptoms (30:36-34:20) - Diagnosis (34:21-36:32) - Final Thoughts We used the following websites, which provide a wealth of information, so please review these for further guidance:
https://www.diabetes.org.uk/about-us/about-the-charity/our-strategy/statistics?gad_source=1
https://www.bmj.com/content/374/bmj.n1449#:~:text=What%20causes%20type%202%20diabetes,a%20decade%20(fig%201). You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q  As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening!

In this episode we discuss 3 of the National screening programmes in the UK: breast cancer, bowel cancer and cervical cancer. We also discuss prostate cancer as this is the most common cancer in UK males, but does not have a screening programme and we go into the reasons why. Details regarding diagnosis rates, what the individual screening test involves, personal experiences and some frequently asked questions are all included in this podcast. It is important to understand screening eligibility and why we provide such programmes within the UK, therefore, even if you think you will never be affected by the condition, at least understand why you are being offered this. You can skip to the relevant sections if needed: (00:00-01:29) - Introduction (01:30-07:00) - Breast Cancer (07:01-14:38) - Bowel Cancer (14:39-21:00) - Cervical Cancer (21:01-28:07) - Prostate Cancer (28:08-30:32) - Final Thoughts We used the following websites, which provide a wealth of information, so please review these for further guidance: https://www.cancerresearchuk.org/ https://www.gov.uk/government/collections/population-screening-programmes-document-collection https://www.nhs.uk/conditions/nhs-screening/ You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening!

In this episode we delve into the topic of stress and what happens when this defence system becomes inappropriately heightened, leading to what is commonly known as chronic stress. We discuss what the NHS currently offer to patients to manage the condition, as well as discussing our own experiences with stress and what strategies we have used to overcome it. As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! You can also watch this podcast episode on YouTube: https://www.youtube.com/channel/UCAf1zFQF4_dyVG4z8DD0_3Q Useful links: Breathing technique - https://www.health.harvard.edu/healthbeat/learning-diaphragmatic-breathing BetterHelp - https://www.betterhelp.com/get-started/?go=true&utm_source=AdWords&utm_medium=Search_PPC_c&utm_term=cognitive+behavioral+therapy_b&utm_content=143273539171&network=g&placement=&target=&matchtype=b&utm_campaign=17446962945&ad_type=text&adposition=&kwd_id=kwd-10512750&gad_source=1&gclid=Cj0KCQjwlvW2BhDyARIsADnIe-Ik4m_J-XZ9uS4jAGS0_UNMDqv6GSIDyAoHsNajdtTo0U4DCFToIjYaAtAwEALw_wcB&not_found=1&gor=start

Our latest podcast assesses our lifestyle changes utilising lipid profiles and HbA1c readings. As we discuss, clinical problems (mainly cardiovascular) manifest over decades and are usually asymptomatic until it is too late. Therefore, over the past 8 months we have adopted a largely whole food diet (ultra processed food makes up no more than 10%) to see if this can have a positive impact and the findings are astonishing, especially when you consider our baseline. As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Instagram- @longev8y

With over 1 in 4 of adults in the UK classed as obese, we address some of the issues relating to this health pandemic. We discuss the physiology, complications, monitoring and treatment that is in place for this condition; here are the timings: (00:00-06:50) - What is obesity? (06:51-14:53) - How effective is BMI in a clinical setting? (14:54-33:50) - Is calorie counting outdated? (33:51-43:26) - How is eating regulated? (43:27-1:04:31) - What treatment is available? (1:04:32-1:10:35) - Complications of obesity? (1:10:36-1:16:00) - Summary and future podcasts Here are some studies from the podcast: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7946062/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396444/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9999507/ As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Any questions, please reach out to us and thanks for listening! Instagram- @longev8y

Here we discuss the most popular of the macronutrients…protein. We have reviewed multiple studies to give a new perspective, as we normally only view protein within a body building context, but how does this correlate with our health? We’re sure this podcast will challenge a few of your long-standing beliefs, as it did ours when we have read through the studies. Please note this is an ever evolving science, the key is to be aware that it can change and not stick to advice from over a decade ago. Here are some of the studies: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760812/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723444/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988204/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7349399/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4045293/ Please see our Instagram- @longev8y for the full list, As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Thank you

In this episode we reintroduce ourselves and explain our goal for setting up Longev8y. As always, thanks for listening and please get in touch if you have any questions. Instagram @longev8y

Life threatening emergencies are something that we do not wish to experience, however, all have a common link of early intervention being vital to survival. Performing CPR to someone in cardiac arrest can treble their chance of survival and this can be by anyone who is confident to do so. Our aim is to provide more knowledge to increase people’s confidence so that they could save a life. We also discuss anaphylaxis and we have attached the links to how each brand of adrenaline pen works below, so please take the time to review this as it could be life saving. https://www.epipen.co.uk/en-GB/patients https://adults.jext.co.uk/about-jext/how-to-use/ https://www.emerade-bausch.co.uk/patient/ More information on the recovery position & CPR can be found below: https://www.bhf.org.uk/how-you-can-help/how-to-save-a-life/how-to-do-cpr/learn-cpr-in-15-minutes https://www.sja.org.uk/get-advice/first-aid-advice/unresponsive-casualty/how-to-do-the-recovery-position/

Non-specific lower back pain accounts for 85-90% of back pain presentations and the management is not consistent across health care providers. In this episode we look into the other types of back pain, when to refer and how to tackle this common, yet disabling condition to get the most efficient recovery. We did mention sleeping positions in the podcast and the below is a link for you to review: https://redefinehealthcare.com/top-5-sleeping-positions-for-back-pain/ As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Thanks for listening! Instagram- @longev8y

Vitamin D, probably the most widely known, has a large impact on our health. Living in the UK, we do not get enough sunlight for at least half of the year, further increasing our risk of deficiency. With more companies offering vitamin supplementation, should we know more about their effects? Do we know safe dosing limits? What monitoring is required? This information has been known to have been omitted from the packaging leading to hospital admissions due to over supplementation leading to endocrine and electrolyte disturbances. In this podcast we discuss some helpful tips for supplements and when you should seek further advice. As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Thanks for listening! Instagram- @longev8y

You may see most people kickstart a diet 6-12 weeks before their holiday, so they can look good and over indulge; but, does your health stay on hold whilst you are away? This podcast is a bit different from our recent ones as we give our perspective of travelling and how we maintain our lifestyle to maximise our health. We do touch upon travel tips and below are the links to check for vaccinations/requirements when entering your selected country: https://www.fitfortravel.nhs.uk/home https://travelhealthpro.org.uk/index.php https://www.nhs.uk/vaccinations/travel-vaccinations/travel-vaccination-advice/ As always, these podcasts are for informational purposes only and should not be used in substitute to seeing a health care professional. Instagram- @longev8y

Going the gym is something we are familiar with (although many might not go) and the concept is to perform exercises for a set period of time; however, this hasn't always been the case. The gym has arguably been formed due to a lack of physical activity in the modern way of life, but we need to move more frequently outside of a gym environment. This podcast discusses what exercise we should be aiming for, the impacts on our risk of frailty, health benefits and whether it's as simple as just to burn some calories... As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Thanks for listening! Instagram- @longev8y

Dyslipidaemia (abnormal blood fat composition), is a leading course of cardiovascular conditions and we do not treat this risk like any others. With treatments that have gained a bad press (namely statins), patients are reluctant to address their cholesterol as they cannot feel the ill effects at present. From a health care professional, the guidelines and targets are ever moving, making treating such cohorts a difficult process. In this podcast, we aim to provide an insight into the importance of treatment and how to go about this. As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Thanks for listening! Instagram- @longev8y

Hypertension (high blood pressure) affects over 1 in 4 adults in England and is not viewed as serious as we think it should be. With no symptoms present in the majority of cases, why would you treat such a condition and surely it cannot be that bad? Sadly, it is this reason that makes this condition so devastating and we hope to make you more aware of this. Below is the link that shows you how to take your blood pressure at home: https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/tests/blood-pressure-measuring-at-home#:~:text=Rest%20your%20arm%20on%20a,two%20fingers%20underneath%20the%20cuff. As always, this podcast is for informational purposes only and should not be used in substitute to seeing a healthcare professional. Thanks for listening! Instagram- @longev8y

In this week's episode, we discuss a heart condition that is being diagnosed at an alarming rate and the majority of the population will be unaware of this. Atrial fibrillation carries an unwanted stroke risk, which is why more publicity is required, given strokes can be life changing, or even worse, cause of death. As a side note, we mentioned the CRY charity, who provide ECGs for young people (no previous cardiac problems are required to meet the criteria) for no charge due to the rise in cardiac problems at sporting events (https://www.c-r-y.org.uk/screening/). As always, this is for informational purposes only and should not be a substitute to seeing a health care professional.

Ultra processed foods form the majority of energy consumption within the UK and since their introduction, non-communicable diseases have increased... a coincidence? We aim to discuss this novel area of science and bring light to arguably the biggest factor that can impact our health, our diet.

In todays episode we discuss GLP1's (glucagon-like-peptide-1 agonists), more commonly referred to 'The Skinny Jab' by the media. Over the last few years they have become a revolutionary treatment option for people living with obesity, who previously wouldn't have had a bridge between over the counter orlistat and the more extreme bariatric surgery. Unfortunately, due to influencers on social media sites documenting their journey of using the medication, branding it as a wonder drug that requires the user to not change anything within their lifestyle to loose significant amounts of weight. Coupled with them being highly accessible via online platforms, they are increasingly being used inappropriately. This has lead to a number of issues for patients and health professionals. We discuss these issues and provide practical information including; their mechanism of action, long term consequences and the potential dangers of GLP-1s when not used correctly, in line with national guidance.

In this week's podcast we discuss hypothyroidism (under active thyroid), a condition that affects approximately 3.5 million people in the UK and is often mistakenly blamed as the cause for people's weight gain. We discuss causes, treatment and complications and try to provide practical information to be able to interpret what it all means. Please note this is for informational purposes only and should not be a substitute to seeking medical advice.

In this episode we discuss diabetes MODY (maturity onset of diabetes in the young), which only accounts for 20-40,000 diagnoses in the UK. The reason being that Lee was diagnosed with this at the age of 10 and has had minimal intervention since, possibly due to the lack of knowledge surrounding genetic forms of diabetes. As mentioned in the podcast, the following link can be accessed to calculate your risk of MODY and as always, if you have any concerns you should seek medical advice as this podcast is for information purposes only. https://www.diabetesgenes.org/exeter-diabetes-app/ModyCalculator Links to the website: www.longev8y.co.uk Instagram: @longev8y Thank you for listening!

In our introductory episode, we discuss the reasons behind starting a podcast and an overview of what is to come. With over 10 years clinical experience between us, we witness how our health is impacted by preventative conditions. However, it took 14 hours in an A&E department as a patient to finally give us that push to release a series of informative podcasts and empower you to greater health.