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PODCAST · health

The DNA of Things with Dr. Jeremy Koenig

The DNA of Things," hosted by Dr. Jeremy Koenig, is an auditory journey into the evolving world of health science, performance, and longevity. This podcast brings together the sharpest minds in the field, including elite health strategists, pioneering scientists, and wellness mavericks, to share cutting-edge practices and revolutionary insights. Each episode is meticulously curated to enrich your understanding of well-being and to extend your vitality, propelling you toward a future filled with possibilities. Join Dr. Koenig as he unveils the secrets of human potential through the lens of genomics, and discover how to transform your health and life trajectory.

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  1. 113

    Episode 120: Dr. Bruce Dame - The Hot Springs Hypothesis and the Origin of Life

    How did life actually begin — and did it start in Yellowstone's boiling hot springs instead of the deep ocean? In this episode, astrobiologist Dr. Bruce Damer joins Jeremy to unpack the hot springs hypothesis, the origin-of-life theory he co-developed with biophysicist David Deamer that's reshaping how scientists think about where the first living cells came from. Bruce walks through the childhood vision at age 14 that set his entire career in motion, the wet-dry cycling experiments in volcanic pools that produce trillions of protocells, and why his NASA background in virtual worlds and asteroid mining eventually looped back into origin-of-life research. The conversation goes deep into the Drake Equation, the Great Filter, and whether complex life might be vanishingly rare in the universe — then takes an unexpected turn into consciousness, psychedelics, and whether humans are tapped into a larger energetic field none of us fully understand yet. If you're into astrobiology, space science, or just love a good "how did any of this even happen" rabbit hole, this one delivers.Key Takeaways:🌋 The hot springs hypothesis says life may have started in cycling volcanic pools, not the ocean 🧬 Wet-dry cycling in hot spring analogs produces trillions of protocells in the lab 👁️ Bruce's origin story starts with a literal vision at age 14 that mapped out his entire career 🚀 Two decades of NASA work on rovers, space stations, and asteroid mining fed straight back into origin-of-life science ☄️ Meteorites carry prebiotic ingredients like amino acids and nucleobases that may have seeded early Earth 🔭 The Drake Equation and the Great Filter suggest we might be genuinely alone in the cosmos 🧠 Carl Woese's "progenote" theory reframes evolution before cells even existed 🍄 A candid dive into ayahuasca and psychedelics as tools for creative and scientific insight 💫 A closing theory on whether humans tap into a shared conductive energetic field 👨‍👧 Why raising a child might be the most direct path to understanding "duty of care" in an AI-driven worldConnect with guest:BIOTA Institute (his research org, Hot Spring Hypothesis): https://biota.org/Personal archive site: https://damer.com/Research profile / publications: https://www.researchgate.net/profile/Bruce-Damer LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  2. 112

    Episode 119: His Testosterone Was 159. What Happened Next Changed Everything with Kyle Hulbert

    At 22, Kyle Hulbert was doing everything "right" — clean diet, eight hours of sleep, daily workouts — and still found himself standing on a 27th-floor balcony in Dubai, depressed and suicidal, with doctors telling him nothing was wrong. It took a functional medicine physician to uncover the real problem: rock-bottom testosterone and chronic mercury poisoning. That diagnosis didn't just save his life — it became the blueprint for Longevity Clinics of America, a functional medicine model built to be affordable instead of another concierge health perk for the wealthy. In this episode, Kyle sits down with Dr. Jeremy Koenig to unpack how pharma funding shapes medical school curriculums, why testing for root causes shouldn't cost thousands of dollars, and how he's scaling a business that runs consults at a loss because he believes access, not upsells, is what actually saves lives.Key Takeaways🧠 Suicidal at 22 despite a "perfect" lifestyle — until testosterone testing changed everything 💉 His testosterone came back at 159 — ten times lower than normal for his age ⚡ Mental health cleared up in just 7 days after starting hormone therapy ☠️ Chronic mercury poisoning was the hidden root cause behind years of fatigue, brain fog, and joint pain 🏥 Why medical schools are funded by pharma — and what that leaves out of doctor training 💰 Functional medicine testing can cost thousands, pricing out everyone but the wealthy 🩺 How Kyle and his business partner built a pricing model that undercuts the concierge health industry by 10x 📉 Clinics intentionally operate consults at a loss because "treatment gives value, not the consult" 🌍 The goal: 10-20 clinics across America to make functional testing accessible, not exclusive 🏠 Simple home heuristics — mold, water filtration, movement — that can catch problems before they become a crisis 👨‍👩‍👧 Why parents should get their kids tested for the same toxicities they struggled with 📺 The "Netflix test" — a surprisingly simple gut check for whether your lifestyle needs an intervention LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  3. 111

    Episode 118: How AI Found What 15 Years of Dermatologists Couldn't | OK Capsule's Dr. Andrew Brandeis

    Dr. Jeremy Koenig sits down with Dr. Andrew Brandeis, CMO and co-founder of OK Capsule, for a wide-ranging conversation about the real reason personalized supplements fail: it's not the science, it's the logistics. Andrew shares his journey from naturopathic physician working alongside MDs in San Francisco urgent care to building a manufacturing-as-a-service platform that pre-sorts and drop-ships personalized daily vitamin packets for supplement brands worldwide. The two dig into supplement quality scandals, the psychology of adherence, and how AI — specifically Claude — is quietly becoming a diagnostic thought partner for both doctors and patients. Andrew even tells the story of how an AI chat uncovered the real root cause of his decade-plus psoriasis flare-ups after dermatologists came up empty. The episode closes with a look at OK Capsule's new MCP integration (basically an AI-native API that turns weeks-long tech integrations into a single click), plus a teaser for Andrew's upcoming satirical novel on how blockbuster drugs actually get made — through marketing, not medicine.Key Takeaways💊 Supplements only work if three things line up: the right formula for the right condition, verified label-accurate quality, and actual consistent adherence — most plans fail on that third one🏭 OK Capsule isn't a supplement brand — it's an API/MCP-driven platform that lets other supplement brands offer personalized, private-labeled daily packs at scale📉 Independent testing has repeatedly found a shocking number of Amazon supplement products don't actually match their label claims — brand trust exists for a reason🤖 AI tools like Claude are becoming a "second opinion" layer for both patients and physicians — pulling years of labs, wearables, and raw genetic data into one context window no human doctor could hold in their head🧬 Andrew's real-life psoriasis case: 15 years of dermatologists saying "it's genetic, here's a steroid cream" — until an AI-assisted deep dive into his raw 23andMe data flagged a specific immune overreaction to a common skin yeast, and treating that actually resolved it🔌 MCP (Model Context Protocol) is being called "the new API" — reducing what used to be weeks of engineering integration work down to a single click for AI-to-AI systems📊 Function Health and its wave of copycats nailed the "here are your results" part of personalization — but most stop short of actually delivering a physical product or solution, which is the gap OK Capsule fills👨‍👩‍👧 A fascinating tangent on where this is all headed: "family LLMs" that hold context across a household's health history, habits, and dinner-table conversations📚 Andrew's satirical novel Pillars: Science and Other Profitable Lies (out early 2027) pulls back the curtain on how pharmaceutical "blockbusters" are really built — through marketing narratives, not necessarily medical superiority🎯 Big picture theme: stop waiting for better information and start building better infrastructure — make the healthy choice the easy choice, and behavior change follows automaticallyChapters List: 00:47 Transitioning Roles: From CEO to CMO 05:50 The Journey to OK Capsule: Foundational Insights 09:34 Building a Platform for Personalized Supplements 13:04 Navigating Quality and Compliance in Supplements 16:06 AI in Healthcare: Opportunities and Challenges 19:00 The Rise of Personalized Health Solutions 21:30 Innovations in AI and Health Integration 25:29 The Impact of MCP on Health Management 28:47 Personalized Supplements and Health Outcomes 32:40 AI as an Augmentation Tool for Doctors 39:02 The Future of Personalized Health and Family Dynamics 41:41 Closing Thoughts and Future Directions  LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  4. 110

    Episode 117: The Molecule That Made Rats Live 90% Longer — Chris Burres on ESS60 & The Science of Aging

    Chris Burres has spent over three decades chasing a molecule most people have never heard of, and the story behind it sounds almost too wild to be true. In 2012, a French toxicity study accidentally discovered that Carbon 60 (ESS60) extended rat lifespans by 90%, making it one of the longest mammalian longevity results ever recorded in peer-reviewed research. On this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Burres, co-founder of SES Research and founder of My Vital C, to unpack the science of oxidative stress, mitochondrial health, and his own BOSS Theory (Buffering Oxidative Stress System). From the Nobel Prize-winning discovery of the molecule at Rice University to real-world testimonials on sleep, energy, and mental focus, this conversation dives deep into carbon nanomaterials, biohacking, and what it actually takes to buffer aging at the cellular level.Key Takeaways🧬 The 90% Longevity Study — How a 2012 French toxicity study on Carbon 60 accidentally became one of the longest-recorded lifespan extensions in mammal history⚗️ From Nobel Prize to Supplement Shelf — The 1985 Rice University discovery of the C60 molecule and its 11-year path to a Nobel Prize in Chemistry🔋 Mitochondria & Oxidative Stress, Explained — Chris breaks down the BOSS Theory (Buffering Oxidative Stress System) using his now-famous Mardi Gras/bumper cars analogy😴 The Sleep-Energy Connection — Why the most consistent testimonial from ESS60 users is better focus and energy during the day paired with deeper sleep at night🧪 The Messy Supplement Industry — Why Chris resisted entering the supplement space for years, and what finally changed his mind💊 Real Protocols & Dosing — Olive oil vs. avocado oil vs. MCT oil, and how Chris personally stacks his morning routine📊 What's Next: Ongoing Research — Upcoming studies on headaches, HS-CRP inflammation markers, sleep, and skin aging🎁 Free Resources for Listeners — Chris shares an 18-tip biohacking guide from his Longevity Summit interviews with 57 experts, plus an exclusive discount link LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  5. 109

    Episode 116: Death by Five-Minute Paper Cuts: Fixing Functional Medicine's Data Problem with Jeremy Malecha

    Jeremy Malecha spent his career building cloud-connected medical devices at ResMed before functional medicine pulled him in through the side door — literally, as his wife's first patient. What he found was a mess: lab results in one place, wearable data in another, supplement protocols scribbled into a Word doc, and zero way to connect any of it. That frustration became Biocanic, a platform now used by thousands of practitioners and over 270,000 patients to turn raw biomarker data, wearable streams, and intake forms into structured, repeatable protocols. In this conversation, Jeremy and Dr. Jeremy Koenig dig into why functional medicine is data-rich but action-poor, how AI changed the speed of building personalized care tools almost overnight, why "death by five-minute paper cuts" is quietly burning out practitioners, and what it actually takes to scale individualized health without losing the personalization that makes it work. They also get into the bigger shift happening post-pandemic — from "doctor knows best" to "I'm responsible for my own health" — and why that shift, not better algorithms, is what's actually going to disrupt healthcare.Key Takeaways:🧬 How Biocanic turns scattered labs, wearables, and intake data into one trackable health record ⏱️ Why "death by five-minute paper cuts" is the real bottleneck stopping practitioners from scaling 🤖 What changed for health tech builders once AI tools caught up to what Jeremy was doing back in 2018 📊 Why functional medicine is data-rich but action-poor — and what closes that gap 🔁 How practitioners build repeatable protocols without sacrificing personalized care 💍 Using wearables (Aura, Whoop, Garmin) and self-experimentation to catch health shifts before they become problems 🩺 The difference between functional medicine patients, health optimizers, and longevity biohackers — and why practitioners serve them differently 🏥 Why healthcare disruption is coming from outside the system, not from insurance or hospitals 🧠 The "teach a person to fish" philosophy behind personalized health coaching ❤️ Why the real metric of long-term health might be relationships, not biomarkers LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  6. 108

    Episode 115: Your DNA Isn't a Death Sentence - Kate Wilson on Genetics, Story, and the Future of Genomic Access

    Kate Wilson has spent over twenty years watching the genetics field move faster than the people it was built to serve — patients in rural communities who didn't know their tumor could be tested, payers drowning in $60,000 EOBs with no answers, and clinicians too overwhelmed to keep up with next-gen sequencing as it was happening in real time. In this episode, Kate — certified genetic counselor, former product director at Quest Diagnostics, clinical instructor at Emory, and host of the award-winning All Access DNA podcast — joins Dr. Jeremy Koenig to pull back the curtain on what genomic medicine access actually looks like on the ground, why the research-to-clinic handoff still takes up to 17 years, and why the future of genetic counseling lives in primary care, not specialty clinics. From the Angelina Jolie BRCA moment that shifted public awareness overnight, to the quiet dismantling of the CDC's public genomics program, Kate traces the thread most people in the field haven't noticed — and makes the case that data alone has never changed a life. Story does.🧬 Key Takeaways🧵 The thread nobody's pulling — Kate spent 20+ years connecting clinical genetics, industry, payers, and the general public — a role that barely had a name when she started💸 The $60K EOB moment — a single panel test, a patient in shock, and a lab with no answers — the story that pushed Kate out of clinic and into industry to fix the system upstream🧪 Sanger → NGS → panels → AI — how the pace of genomic innovation outran clinician education, payer policy, and patient awareness all at once📣 Why data doesn't move people — stories do — Kate's philosophy on science communication and why All Access DNA was built around human narratives, not lecture slides🏥 The primary care gap — why genetic counselors belong in your family doctor's office, not just specialty clinics, and what a few pioneering practices are already proving🌍 Access isn't just about cost — rural communities, under-informed clinicians, and outdated insurance guidelines are the real barriers to genomic medicine reaching everyone⚖️ ELSI in practice — the ethical, legal, and social implications of DNA testing including life insurance blind spots and why Huntington's disease is still the clearest test case for voluntary genetic testing🤝 The three-legged stool — why academics, industry, and government genomics programs have to work together — and what's at stake now that the CDC's public genomics group has been cut🔬 Genetic counselors in industry — the surprising skill that makes GCs invaluable in boardrooms: translating between bioinformatics, C-suite, and payer policy in the same room✨ Room for miracles — why Kate, after 20+ years of reading genetic data, still believes a result is never the whole story LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  7. 107

    Episode 114: Erik Jivmark on Why a Billion People Have Sleep Apnea — and 80% Don't Know It

    Most people know Sleep Cycle as the app that wakes you up at the right time. Erik Jivmark, CEO of Sleep Cycle, is here to tell you it's something much bigger than that. In this episode, Erik breaks down how a shift from motion tracking to audio-based breathing analysis turned a consumer sleep app into one of the most valuable passive health datasets on the planet — 82 million installs, four billion nights tracked, and 11 million hours of sleep analyzed every single day. We get into the science behind contactless sleep apnea risk detection, why 80% of the estimated one billion people living with sleep apnea remain undiagnosed, and how Sleep Cycle is working toward FDA clearance for a one-night, no-hardware screening tool that lives entirely on your phone. Erik also pulls back the curtain on their B2B SDK strategy, their partnerships with Ultrahuman, Carnegie Mellon, and the UK Health Security Agency, and why he believes the real barrier to solving sleep apnea at scale isn't technology — it's access.EPISODE TAKEAWAYS:😴 Why sleep is the single most underrated lever for mental health, weight loss, athletic recovery, and cognitive performance📱 How Sleep Cycle detects sleep stages, snoring, and respiratory rate using only your phone's microphone — no wearable required🌍 The story behind 4 billion nights of sleep data tracked across the US, UK, Germany, Japan, Brazil, China, and Australia🫁 What breathing patterns during sleep reveal about your overall health — and why breath became the key signal🚨 The sleep apnea epidemic: 1 billion people affected, 80% undiagnosed, and why primary care can't keep up🔬 Inside Sleep Cycle's clinical validation study for FDA-cleared sleep apnea risk detection using a single overnight recording⌚ How Sleep Cycle's accuracy stacks up against Apple Watch and Samsung's wearable-based sleep apnea tools🤝 The B2B SDK strategy: how companies like Ultrahuman integrated Sleep Cycle's full tech stack in under two weeks📊 CoughRadar explained — how anonymous cough data tracked nightly is helping public health agencies monitor flu and respiratory illness across entire countries💊 Why progressive doctors are now prescribing better sleep before medication for depression, anxiety, and metabolic conditions🏃 The biohacker's shortcut: why fixing sleep delivers more growth hormone and testosterone than almost any supplement or training protocol🏠 Beyond the phone — how Sleep Cycle's audio SDK is being embedded into smart home devices for passive, always-on health monitoring LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  8. 106

    Episode 113: Stop Treating the Tire, Fix the Alignment: Neuro-Reconditioning Secrets from 37 Years in Elite Sport with Scott Livingston

    If you've ever rehabbed an injury only to watch it come back six months later, this episode is going to change how you think about your body. Scott G. Livingston — Master Neuro-Reconditioning Practitioner, Athletic Therapist, Strength & Conditioning Coach, keynote speaker, and host of the Leave Your Mark podcast (now in its 9th season, nearly 500 episodes strong) — joins Dr. Jeremy Koenig to break down exactly why the traditional medical model keeps missing the point. With 35+ years in high-performance sport, 11 NHL seasons with the Montreal Canadiens, New York Rangers, and New York Islanders, and multiple Olympic and World Cup medalists trained personally, Scott has seen every version of how the industry gets it wrong. His methodology, neuro-reconditioning, starts where most practitioners stop: the nervous system. Scott unpacks why patellar tendinitis, ACL tears, and chronic pain aren't the problem — they're the symptom. The real driver lives in walled-off movement patterns, outdated threat responses, and the long-standing communication breakdown between rehab and performance that almost nobody is trained to bridge. Now stepping into his newest role as Head of Rehabilitation for injured touring performers at Cirque du Soleil, Scott brings that same philosophy to some of the most extraordinary athletic bodies on the planet. Whether you're a clinician, a coach, or an athlete tired of being reactive, this conversation will push you to stop treating the vibration and start asking what's wrong with the alignment underneath.🎯 EPISODE TAKEAWAYS🧠 The nervous system runs the show — chronic and recurring injuries almost always have a neurological root cause that the traditional diagnostic model completely ignores🔧 Treat the alignment, not the tire — pain and injury are symptoms (the vibration), not the actual problem; the worn tire is not why the tire wore out🏒 11 NHL seasons across three franchises — Scott's elite hockey career with the Canadiens, Rangers, and Islanders gave him a front-row seat to how world-class bodies break down and what it really takes to bring them back🥇 Olympic and World Cup medalists trained personally — Scott has worked at every level of sport, giving him a uniquely broad lens into how different athletic profiles move, compensate, and recover🩹 Rehab and performance are still siloed — most practitioners speak only one language; Scott built Reconditioning HQ to give clinicians and coaches a shared vocabulary and methodology⚙️ Reconditioning vs. rehabilitation vs. performance therapy — these are not the same thing; Scott breaks down the critical difference using the F1 pit crew analogy🔁 Previous injury is the #1 predictor of future injury — without addressing the neurological compensation patterns left behind, you're just replacing the tire again🧬 Your genetic profile is your stock vehicle — DNA informs whether you're built like an off-road truck or an F1 car, and no amount of training fully rewrites that blueprint🤸 Artistic athletes changed how Scott sees movement — working with freestyle skiers and aerial performers revealed how the body can do extraordinary things without conventional gym training📋 The prehab revolution is overdue — the tools exist to be proactive, but the industry is still largely reactive; Scott argues for identifying "skeletons in the closet" before they ever become injuries🎪 Cirque du Soleil as the ultimate reconditioning lab — elite performing artists present a unique challenge: genetically exceptional movers who still need intelligent load management and long-term return-to-performance care🎙️ Leave Your Mark podcast — 9 seasons, nearly 500 episodes — Scott's platform interviews people from all walks of human performance, exploring the personal stories behind their excellence🤝 Apprenticeship still matters in the AI age — shared information and technology are powerful, but 30–40 years of practitioner nuance can't yet be replicated by any algorithm💡 Pain is a messenger, not the message — the body walls off movement it no longer considers safe; the goal is to understand why, not just silence the signal LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  9. 105

    Episode 112: Garbage In, Garbage Out: Why Your Wearable Might Be Lying to You with Marco Benitez

    Most health tech companies are racing to build the insight — Marco Benitez went and built the thing underneath it. Marco is the co-founder and CEO of Rook, the API platform that normalizes and standardizes data from 400+ wearables into one clean, usable signal. In this episode, he breaks down why dirty wearable data is silently corrupting health decisions across insurance, pharma, remote patient monitoring, and clinical trials — and how a biomedical engineer with a fourth-dan taekwondo black belt and a background in big pharma saw the problem before anyone else wanted to admit it existed. From a hardware pivot during COVID to landing Fortune 15 clients, Marco's story is a masterclass in building the boring, hard infrastructure that the entire longevity and digital health world quietly depends on.What You'll Learn:🩺 Why your Apple Watch, Garmin, and Oura Ring don't actually agree — and what that means for your health data🍍 The pineapple vs. apple problem — how wearable data looks similar but is fundamentally incompatible across devices🧬 How clean data is the real bottleneck in digital health, longevity, and clinical research⚙️ What it actually takes to build the infrastructure layer beneath digital twins, remote patient monitoring, and wearable analytics💊 How big pharma's clinical trial standards shaped Marco's obsession with data accuracy from day one🔄 Why Rook pivoted from hardware to software — and how that decision unlocked Fortune 15 clients🤖 Where the digital twin is today vs. where AI is taking it in the next decade🚗 Why Marco compares the future of health AI to Tesla's self-driving — and why that analogy actually holds up🥋 What 15 years of taekwondo taught Marco about building a company, a team, and a life LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  10. 104

    Episode 111: "You Can't Sprint — Yet: What Olympic Coach Stuart McMillan Wants Every Athlete (and Non-Athlete) to Know About Speed

    Stuart McMillan has coached at 10 Olympic Games, helped athletes from 19 countries medal in Rio, and built ALTIS — one of the most respected human performance organizations in the world — out of a million dollars of debt and what he openly calls "straight-up chaos." In this episode, Stuart breaks down what speed actually is, why almost nobody — including trained athletes — can truly sprint, and why that gap between your engine and your chassis is exactly where injuries are born. He unpacks the most overlooked principles of sprint training, explains what "earning the right to sprint" really looks like for everyday people, and shares how decades at the tip of the spear with the fastest humans alive have shifted his focus toward something bigger: helping the rest of us move well, move fast, and keep doing it for decades to come.🔑 What You'll Learn in This Episode⚡ Why most people literally cannot sprint — and what to do about it before you try🏗️ The engine vs. chassis framework — why raw power means nothing without the structure to handle it🏅 What it took to coach athletes from 19 countries to the 2016 Rio Olympics — and what nearly broke ALTIS getting there🐢 The counterintuitive lesson Stuart gives every athlete, coach, and entrepreneur: slow down to go fast🧠 The "seek, sense, share" knowledge framework Stuart has used since 2010 to stay at the frontier of performance🏃 What sprinting actually is — and why your Tabata workout absolutely does not count🔧 How Dan Pfaff turned a long jumper with 17 hamstring tears in 3 years into an Olympic gold medalist🎓 Why traditional coaching education is failing athletes — and what ALTIS is building to fix it🌍 How Stuart is taking elite sprint science out of the track and into the hands of everyday people🔮 What the next 10 years looks like for one of the most influential performance coaches alive LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  11. 103

    Episode 110: Your Body Can Heal Itself — Here's the Science Behind It | Christian Drapeau on Stem Cells & Longevity

    What if your body already has everything it needs to repair itself — and the real problem is that we've been ignoring it? In this episode of DNA of Things, host Jeremy Koenig sits down with Christian Drapeau, stem cell researcher, neuroscientist, and founder of STEMREGEN®, for a conversation that genuinely shifts how you think about aging, recovery, and chronic disease. Christian breaks down how stem cells function as the body's built-in repair system, why that system starts declining as early as your 30s, and what that gradual breakdown actually looks like — from slower recovery after a workout to the onset of age-related disease. He walks through his 25+ years of research, starting with a blue-green algae that sparked an entirely new field of inquiry, and explains how specific plant compounds can mobilize your body's own stem cells to support healing from the inside out. Whether you're an athlete trying to bounce back faster, someone managing a chronic condition, or just trying to build a body that holds up for the long haul, this episode lays the scientific groundwork for why endogenous stem cell mobilization might be the most overlooked pillar of human health today.Takeaways:🔬 Stem cells are your body's repair system — not just a medical procedure, but an active, ongoing biological process happening inside you right now📉 By age 30–35, you've lost ~90% of your circulating stem cells — and that decline is directly tied to slower recovery, tissue degeneration, and age-related disease🌿 Plants can mobilize stem cells — Christian Drapeau's research identified 15+ plant compounds that stimulate stem cell release, with the top 5 now formulated into STEMREGEN®💊 Endogenous vs. exogenous stem cells — why supporting your own stem cell production is a fundamentally different (and more sustainable) approach than injections or stored cord blood🏋️ Athletes can feel the difference within 24 hours — post-workout recovery, soreness, and tissue repair all tied directly to how many stem cells are in circulation🫀 Chronic conditions like congestive heart failure showed 10/10 recovery in a study where mitochondrial function was restored — pointing to stem cell mobilization as a root-cause intervention🧠 The medical system doesn't ask the most important question — "Is this person's repair system failing?" — and Christian Drapeau argues that answer underlies almost every chronic condition past age 45🤝 A collaboration with Dr. Jeffrey Bland (the father of functional medicine) is underway, bridging endogenous stem cell science with STEMREGEN®'s approach to regenerative health⏳ Paradigm shifts take time — Christian draws a compelling parallel to handwashing in the 1800s: the science is solid, but cultural and medical acceptance lags decades behind the data🌍 100,000+ people are already using STEMREGEN® — and the next frontier is getting this into the hands of healthcare practitioners who can document outcomes at scale LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  12. 102

    Episode 109: "No Diploma, No Limits: From Dropout to Mars Commander with Dr. Kelly Haston"

    Dr. Kelly Haston didn't take the traditional road — she left home at 15, has no high school diploma, and rebuilt her entire life through California's community college system before earning her way to Berkeley, UCSF, and Harvard. Now she's one of the few humans on earth who knows what 378 days inside a sealed Mars simulation actually does to your mind, your relationships, and your sense of what matters. As a stem cell biologist and commander of NASA's CHAPEA analog mission, Kelly brings a molecular lens to questions most people haven't even thought to ask yet — what does reduced gravity do to a developing human embryo, what will our garbage do to Mars, and how do four unconnected people stay psychologically intact for a year with no way out and a 22-minute communication delay? This conversation goes from a garage in British Columbia where a young girl pulled a leg off a salamander to the cutting edge of what humanity might actually look like when we leave this planet for good.Takeaways:🦎 The childhood salamander experiment that quietly predicted Kelly's entire scientific career🎓 How the US community college system gave a high school dropout a path to Harvard and NASA🔬 Why being at the start of a field — not the middle of it — is where the most important science gets done🚪 The unspoken door rule inside the Mars habitat and what it reveals about human psychology under isolation⏱️ How a 22-minute communication delay forces radical autonomy — and what that means for future Mars crews🧬 The difference between cellular aging and maturation, and why it matters before we send humans to deep space👶 Why having babies in space or on Mars is one of the most underexplored and urgent questions in human biology🤝 What a year away from everyone you love teaches you about the non-negotiable value of human connection😌 Why Kelly now takes urgent things less seriously — and why that perspective shift might be the most transferable lesson from the mission🌍 The COVID parallel: why humans need common purpose to function, and what Mars colonization might finally force us to figure out about ourselves LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

  13. 101

    Episode 108: "She Built the Test That Didn't Exist" — Denisa Kim on Couples' Microbiome Testing & Closing the Gap in Women's Health Diagnostics

    What do you do when the healthcare system fails you — for three years straight? If you're Denisa Kim, you build the solution yourself. A chemical engineer turned biotech founder, Denisa spent years battling chronic recurring UTIs before discovering a glaring blind spot in women's health diagnostics: every at-home microbiome test on the market only tests one person. So she founded Anteros Bio, the first platform to test both partners and compare their genital urinary microbiomes side by side — because vaginal health, as it turns out, has never been just one person's biology. In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Denisa to unpack her journey from Facebook support groups to pitch stages, from bubble-mailer MVPs to utility patents, and from bootstrapped solo founder to actively fundraising with a growing clinical network. They go deep on the science of microbial compatibility, the racial and ethnic gaps in women's health data, why AI alone can't fix what under-researched data sets broke, and what it really costs a founder to protect her own vision when everyone else has a better idea for your company.🔑 What You'll Learn in This Episode🧫 The Partner Blind Spot in Microbiome Testing — Why every existing at-home test ignores half the equation, and how Anteros Bio is solving couples' shared vaginal and urinary health🩺 Chronic UTI & Recurrent Vaginal Infections — The real recurrence rates for UTIs, BV, and yeast infections that modern medicine quietly accepts — and why Denisa refuses to💡 From Pain Point to Pitch Stage — How Denisa went from DMing strangers in Facebook support groups to placing 2nd in a startup competition with nothing but an idea and a voice📦 Building an MVP on a Shoestring — Swabs in bubble mailers, DIY shipping labels, and what "ship before you're ready" actually looks like in biotech🧬 The Science of Microbial Compatibility — What it means to compare two microbiomes at the same time, and why shared health data between partners changes the diagnostic picture entirely🌍 The Gender & Ethnic Health Data Gap — Why women's health research is chronically underfunded, underrepresented, and why solutions built from one population's data don't translate across ethnicities🤖 AI + Microbiome Data: Limitations & Possibilities — Why machine learning can't outrun biased or incomplete datasets, and what truly inclusive sexual health tech needs to look like💸 Bootstrapping, Presale Memberships & Founder-Led Fundraising — Denisa's take on raising smart money vs. fast money, and why not all capital is worth taking🪞 The Founder as Brand — How building in public as a solo founder created audience pressure that nearly pulled her away from her own use case🎯 Protecting Your Vision — The cost of other people's playbooks, and the question every early-stage founder needs to ask: Who is this for — and who am I becoming by building it? LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 107: The 90% Problem: Why Women's Health Has Been Running on Male Data — and How Roma Van der Walt Is Changing That

    Roma Van der Walt didn't stumble into women's health — she was forged into it. Raised by a Kenyan father who never owned a car, Roma was logging long-distance walks by age four, quietly building a resting heart rate that would later make elite coaches take notice. By 12 she had found the coach who would shape everything; by 17 she was writing a university-level thesis on anaerobic threshold training using herself as the test subject; and by her mid-twenties she had retired from Germany's national modern pentathlon team, carrying with her a master's in sports science and a lifetime of data-driven training most athletes never get to experience. But the chapter nobody talks about — the UN desk job, the 40-plus pounds gained post-retirement, the sciatica, a pregnancy complicated by thyroiditis, then a hernia — turned out to be the real research. When the medical system couldn't give her the coordinated, personalized support she knew was possible from her athletic career, she stopped waiting and built it herself. Now, as CEO of Vitelle, Roma is building the health operating system for women — confronting a reality the longevity world has quietly accepted: that 90% of the data driving our health algorithms was collected from male bodies, costing women an estimated 75 million life-years every single year.🧬 How Roma's Kenyan roots and data-driven coach shaped her elite athletic foundation📊 Threshold training vs. VO2 max — and why one is trainable and the other isn't🏅 What modern pentathlon actually demands across five disciplines in a single day🧠 The psychology behind elite performance and knowing when to ditch the data💔 The post-athlete identity crisis — weight gain, sciatica, and losing yourself after retirement🤰 Pregnancy, thyroiditis, hernia — and how Roma rebuilt herself back to marathon PR shape🏃‍♀️ Running an ultra marathon four months postpartum to study her own physiology🤖 Why AI health tools are hallucinating women's health with male benchmarks🚨 The 90% male data gap that is structurally failing every woman in the healthcare system📉 75 million life-years lost annually to poor female care pathways💡 Healthspan over lifespan — why quality of life matters more than the number🏗️ What Vitelle is building and why the world needs a female health operating system LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 106: Why Resistance Training Is the Ultimate Longevity Tool with Dr. Stuart Phillips

    In this insightful conversation, Dr. Jeremy Koenig sits down with Dr. Stuart Phillips—one of the world’s leading muscle physiologists—to explore why resistance training isn’t just for athletes anymore. As the first Canadian to lead the American College of Sports Medicine’s position stand on resistance training, Dr. Stu Phillips shares powerful insights on building muscle for healthy aging, longevity, and staying independent well into your later years. From his epic first meeting with Dr. Mark Tarnopolsky (one limping in on a broken leg, the other riding a bike with a halo bolted to his skull after hitting a moose) to leading the renowned PACE program, they dive deep into the real science of protein, creatine, strength training, and why the biggest longevity hack might not be the latest supplement trend. Dr. Phillips dismantles the “longevity illusion,” outlines the four essential pillars of healthspan, and explains why the strongest thing you can build might not be your body—but your community and consistent daily habits. Dr. Jeremy Koenig and Dr. Stu Phillips deliver practical, no-nonsense advice every “mere mortal” needs to hear.Takeaways 💪 Resistance training isn’t just for jocks — it’s essential for healthy aging and staying independent, says Dr. Stuart Phillips🧬 First Canadian to author the ACSM position stand on resistance training shares the latest science with Dr. Jeremy Koenig🥩 Protein needs explained: why the hype is overblown and the realistic daily target (1.6g/kg)🧠 Creatine benefits go far beyond muscles — including brain and cognitive support📉 Why chasing longevity often misses the mark — focus on healthspan instead🏋️ The 4 big levers that matter most: move your body, eat real food, sleep well, and stay socially connected👴 Inspiring stories from the PACE program: how community and strength training help people thrive at 100+🪑 The most important strength exercise for older adults? Simply being able to stand up from a chair🧹 Why “sweeping the floor” and lab culture reveal deeper lessons about mentorship and grit⚖️ GLP-1 drugs like semaglutide: what they really mean for muscle loss and sustainable results LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 105: The NeuFit Method: Why Your Nervous System Is the Key to Healing Injuries and Unlocking Performance with Garrett Salpeter

    When college hockey player Garrett Salpeter tore ligaments in his wrist and was told he needed surgery, he discovered a radically different path using targeted direct current electrical stimulation to work with the nervous system instead of fighting it. Weeks later, his wrist healed completely without surgery — and a new mission was born.In this episode, Garrett Salpeter, founder of NeuFit and inventor of the FDA-cleared NeoBie (NewFit) device, joins Dr. Jeremy Koenig to explain why traditional rehab often falls short. He reveals how the nervous system’s protective “brakes” keep people stuck in pain, weakness, and slow recovery — and how recalibrating those patterns can dramatically speed healing from acute injuries, post-surgery rehab, and even support neurodegenerative conditions like MS.From the Mayo Clinic and over 100 professional sports teams to everyday athletes and longevity seekers, this conversation dives deep into neuroplasticity, movement readiness, the mind-body connection, and why addressing the body’s “software” is the missing link in both performance and healing.Key Takeaways:🏒 The Hockey Injury That Started NeuFit – How a simple wrist tear exposed the limits of traditional care and sparked a neuroscience-driven company⚡ Nervous System First, Tissues Second – Why guarding, inhibition, and threat perception often slow healing more than the actual damage⏱️ Cut Recovery Time in Half – Turning 4–6 week injuries into 1–2 weeks and accelerating post-op results starting day one🧠 Neuroplasticity for MS & Neuro Conditions – How NeuFit helps rebuild pathways when the body can’t generate enough input on its own💪 Performance Without the Brake – Using “digital weight” and mapping to remove nervous system governors and unlock hidden speed/power🔄 The SAID Principle – Why we’re always adapting to exactly what we do and how to hack it for better movement and longevity🧘 Mind-Body & Psychosomatic Patterns – How physical tension from emotional stress mirrors injury compensation — and how releasing it changes everything📈 Movement Readiness & Future Consumer Tools – The coming era of daily nervous system scans and at-home NeuFit solutions LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 104: 378 Days on "Mars" and Back in the ER by Morning: The Resilience Blueprint of Dr. Nathan Jones

    Dr. Nathan Jones is an ER physician, SWAT medic, and NASA CHAPEA Mission 1 medical officer — and his life reads less like a résumé and more like a dare. In this episode, he traces the thread from a rural Midwest childhood shaped by his father's international eye missions, to overnight shifts in central Illinois, to practicing medicine in the jungles of Honduras, to 378 days sealed inside NASA's simulated Mars habitat with 22-minute communication delays and no hardware store within 140 million miles. It's not a story about credentials — it's what happens when you spend a lifetime saying yes to hard things, guided by four words: do the hard thing now.Key Takeaways:🧬 Resilience is built, not born — forged through repeated exposure to high-stakes, low-resource environments🚑 The Golden Hour mindset — ER decisiveness and knowing when not to act both translate to deep-space isolation🪐 378 days of silence rewires your brain — and that rewiring turns out to be a gift🌿 Scarcity is the best teacher — no help coming means radical creativity kicks in🛠️ The tinkerer's brain is a survival tool — curiosity and problem-solving are repeatable resilience skills👨‍👩‍👧 "Do the hard thing now" is a family operating system — not a motto, a method🔄 Epigenetics shapes performance — individual and family-level signatures may be tuning biology in ways science hasn't mapped yet👁️ Perspective is a survival skill — seeing through someone else's eyes might be the most urgent thing we can practice right now LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 103: From Bell Labs to Your Biology: Why the Next Trillion-Dollar Health Company Looks Nothing Like a Hospital with Dr. Asif Naseem

    What happens when a Bell Labs engineer who built a $90M software business, raised $70M in wireless tech, and watched Intel acquire his company decides to walk into a hospital — and can't unsee what's broken? In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Dr. Asif Naseem, CEO of GenoPalate, to trace one of the most unlikely journeys in health tech. Asif pulls from decades of systems engineering — fault-tolerant networks, broadband infrastructure, Oracle enterprise — to argue that the next trillion-dollar company in healthcare won't look like a hospital. It'll look like a telecom network. With 180,000 customers and a multi-omics vision on the horizon, Asif breaks down why healthcare is still stuck in the 1990s internet era, why point solutions are failing patients, and why the future belongs to whoever builds the intelligence layer — not the app on top of it. If you're a founder, clinician, or just someone who wants to actually understand their own biology, this one will rewire how you think about personalized nutrition, genomics, and what "precision health" could actually mean at scale.💡 Key Takeaways🏗️ Systems over solutions — Healthcare's biggest problem isn't a lack of innovation, it's a lack of infrastructure. Asif argues we need an intelligence layer, not more point products.🧬 Your DNA is a starting point, not a verdict — Genetics is static, but when you stack it with blood biomarkers and microbiome data, you get a living, dynamic metabolic health profile.📡 Healthcare is becoming a telemetry application — Continuous glucose monitors, home diagnostics, and longitudinal tracking are turning the body into a real-time data network — the same way we monitor cars or telecom traffic.🍎 Food is medicine AND poison — Nutrigenomics reveals that what's healthy for one person can be inflammatory for another. Personalization isn't a luxury; it's the baseline.🌐 The next trillion-dollar health company looks like Cisco, not a clinic — The winner won't sell individual tests or reports. They'll orchestrate the whole network and sell the intelligence layer.🔄 Multi-omics is the future of metabolic health — Single data streams (genetics alone, blood alone) aren't enough. The industry is moving toward integrating multiple omics sources for accurate, reliable health predictions.🤝 B2B is the scalability unlock — GenoPalate's pivot from direct-to-consumer to a B2B platform means coaches, clinicians, and wellness providers can now embed precision nutrition into their own offerings.🧠 Agency over your own biology — The end goal isn't another report you file away. It's giving people the tools to query their own biology — no PhD required.🏥 Healthcare in the 90s — Just like the internet before Google and Amazon built on top of it, healthcare infrastructure is being laid right now. The intelligence layer is still up for grabs.🎓 Go learn what you don't know — Asif left Oracle to do clinical rotations at MIT/Harvard Medical School. Sometimes the best competitive advantage is intellectual humility and a willingness to start over. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 102: The Gap Nobody Talks About: Why Great Healthcare Innovation Never Reaches Patients with Mariano Bendersky

    Most healthcare innovation never makes it to the patient — not because the science is wrong, but because nobody figured out how to plug it into the real world. In this episode, Dr. Jeremy Koenig sits down with Mariano Bendersky, Head of Innovation and Digital Healthcare at Sanofi, to dig into the messy, human side of healthcare transformation. Mariano brings a rare combination of private equity instincts, CEO-level operating experience, and front-row seats to some of the most ambitious AI-driven initiatives in digital health — including cutting specialist wait times and building early disease detection programs for Type 1 diabetes. Together, they explore how we've moved from Digital Health 1.0 (connected devices and chronic disease apps) into the AI era, where the bottleneck isn't the model — it's the workflow. From physician burnout and fragmented health data to the cultural divide between how Argentina and the US think about healthcare access, this conversation gets into the real friction points that innovators, investors, and entrepreneurs can't afford to ignore. If you're building in health tech, funding the next wave of digital health companies, or simply paying attention to where medicine is headed, this episode is your reality check — and your call to action.KEY TAKEAWAYS:🤖 AI needs legs, not just a brain — A great predictive model means nothing if it can't plug into clinical workflows. Operationalization is the missing piece most health-tech startups skip.⏱️ Wait times are a systems failure, not a capacity problem — Reducing specialist access from 9 months to something manageable is often an administrative fix, not a clinical one.🔥 70% of physicians are burning out — Admin overload is crushing clinicians, and AI has a real role to play in reducing documentation burden and giving doctors back time with patients.🌎 Healthcare is culturally wired — How a society defines healthcare access, who gets what, and what's considered "fair" differs dramatically between countries like Argentina and the US. Innovation that ignores culture will stall.💡 Digital Health has entered its AI era — We've moved past connected devices and basic apps. The new frontier is using AI to find non-obvious disease markers, predict earlier, and act faster.🏗️ Selling into pharma and health systems is its own skill — Startups need to understand buying cycles, budgeting windows, and who the real decision-maker is — or their best idea will never get a meeting.🧠 Critical thinking is more important than ever — As AI surfaces counterintuitive findings, human judgment is what separates a breakthrough from a dangerous black box.💰 This is the win-win-win moment — When bold innovators, aligned investors, and evolved regulatory frameworks come together around early detection and prevention, everyone wins — including the bottom line.🚀 The call to action: now is the time — The tools exist. What's needed are innovators willing to take calculated risks and investors ready to back a more humane, proactive healthcare system.more on: https://www.sanofi.com/en  LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 101: Get In The Game: How At-Home Diagnostics Are Putting Health Back In Your Hands with James York

    From the fast-paced trading floors of Wall Street to the cutting edge of molecular diagnostics, James York's career path is anything but conventional — and that's exactly what makes his work so powerful. As Chief Commercial Officer at Molecular Testing Labs, James has spent over a decade quietly dismantling one of healthcare's most persistent problems: access. In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with James to unpack how at-home sample collection, self-directed testing, and the convergence of genomics, biomarker data, and AI are reshaping what it means to take ownership of your health. Whether you're a clinician, a digital health builder, or someone who's simply tired of waiting for the system to catch up with your goals, this conversation is a masterclass in why the future of healthcare isn't coming — it's already being built, and it starts with you getting in the game.🎯 Key Takeaways🧬 Molecular diagnostics are no longer just for clinics — at-home sample collection is making lab-quality testing available to anyone, anywhere🏦 Wall Street to wellness — James's background in market-making directly shaped how he thinks about healthcare access and building new systems from the ground up🚧 The real barrier isn't the test — it's the friction — stigma, geography, and economics are the true gatekeepers MTL is working to remove📊 The three-tool revolution is here — genome sequencing + biomarker testing + AI is the new trifecta for understanding your full health picture💊 Pharmacogenomics is going mainstream — CYP/SIP testing is now being recommended in TV commercials, signaling a massive shift in how personalized medicine is being adopted🏃 Your DNA affects your performance, not just your disease risk — from injury vulnerability in elite athletes to how you metabolize nutrients, your genome is a blueprint for optimization🤝 Molecular Testing Labs is the silent infrastructure behind the scenes — they power the workflows so brands, health platforms, and practitioners don't have to build from scratch🏠 Care is moving home — virtual encounters and at-home diagnostics are converging, and the labs that survive will be the ones that connect seamlessly to that shift🧠 AI won't replace the expert — it scales them — the future belongs to the Mr. Miyagi practitioner who can reach thousands of patients without losing the intimacy of care✅ The #1 takeaway: Get in the game — the tools exist, they're affordable, and they're more accessible than ever — curiosity is the only thing standing between you and your health data LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 100: From 23andMe to the Future of Personalized Genomics: Mike Polcari on Building the "Hugging Face of Multi-Omics"

    What happens when the architect behind one of the world's largest consumer genomics platforms decides to build what comes next? In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Mike Polcari — former Chief Architect at 23andMe and now founder of Haplotype Labs — to talk about what the $100 genome actually unlocks, why genetics has been stuck in research labs for too long, and how a new infrastructure layer could finally bring polygenic risk scores into everyday clinical care.If you've ever wondered why your DNA report sits in a PDF collecting digital dust instead of actively guiding your health decisions in real time, this conversation is for you.Connect with Mike: https://www.haplotypelabs.com/contactKey Takeaways🧬 The genome is no longer expensive — interpretation is the bottleneck. Sequencing just crossed $100, but having data and knowing what to do with it are two very different things. Mike estimates we're still about five years from fully understanding an individual's germline genetics.🔬 Polygenic risk scores make genomics useful for everyone. Most people won't carry a dramatic single variant. PRS aggregates thousands of small signals to give meaningful risk predictions for things like heart disease and cancer — making DNA actionable for the masses, not just edge cases.🏗️ Haplo Hub eliminates the infrastructure tax. Building a genomics pipeline used to mean 18 months of engineering and millions spent before offering a single DNA insight. The Hub lets any lab or health brand go from raw data to validated risk scores via a clean API — no bioinformatics team required.🤖 AI chatbots can't replace validated genomic models. Ask ChatGPT for a PRS score and it'll confidently give you a wrong answer. Mike's vision is your omics data living in a secure, continuously updated cloud that health AI platforms can actually query accurately.📡 Your DNA should follow you — not stay locked with whoever sequenced you first. The personal omics cloud means your genome gets reinterpreted as science improves and integrates contextually into every health decision you make.🌐 Telehealth legitimization opened the market. COVID forced mainstream adoption of telehealth, creating national-scale infrastructure for preventative health services — exactly the kind that can finally incorporate genomics into care at scale.🔓 Open science needs a commercial on-ramp. Researchers publish better genomic models every month. Most never reach a clinic. Haplo Hub closes that 15-year translation gap. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 99: The Immune Age Revolution: From Cellular Avatars to Lifelong Health with Vijay Vaswani

    In this episode, Dr. Jeremy Koenig talks with biotech leader Vijay Vaswani, co-founder and CEO of Omniscope, about how decoding the immune system at single-cell resolution is changing how we define true health and extend healthspan.✨ Key takeaways🧠 True age vs birthday age: Your “real” age is your immune age, and elite athletes and centenarians often have surprisingly youthful immune profiles.🧬 From fuzzy maps to HD biology: High-resolution immune sequencing replaces low-resolution lab tests with a much more detailed view of how cells drive health and disease.🏃‍♂️ Athletes as health models: Profiling the immune systems of pro athletes reveals what low-inflammation, high-performance biology looks like in practice.🤖 Immune GPT & cellular avatars: Omniscope’s immune-focused AI and “cellular avatars” help design new drugs, personalize immunotherapies, and give people agency over their biology.❤️ From sick care to healthspan: Longitudinal immune profiling (OS Lifetime) monitors immune age, inflammation, and resilience to shift medicine toward prevention and extended healthspan.Episode Overview:In this episode, Dr. Jeremy Koenig sits down with biotech leader Vijay Vaswani, co-founder and CEO of Omniscope, to explore how decoding the immune system at single-cell resolution is reshaping our understanding of true health and aging. They dig into why your “real” age is your immune age, what we can learn from elite athletes and centenarians, and how high-resolution immune maps move us beyond traditional, low-resolution lab tests. The conversation also covers Omniscope’s immune-focused AI, “cellular avatars,” and longitudinal immune profiling platform, and how these tools could power earlier detection, personalized immunotherapies, and a shift from reactive sick care to proactive, healthspan-focused medicine. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 98: The Trillion-Dollar Bet on Preventative Health with Dr. Travis McDonough

    In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Dr. Travis McDonough — serial entrepreneur and CEO of Wellnify AI — for one of the most honest conversations about the future of preventative health you'll hear. Travis spent decades inside professional sports, helping build Conduct Technologies into a human performance platform that supported 650+ pro sports organizations and 25 world championships before its 2020 acquisition. Then came the bigger question: what if everyone had access to those same tools? That became Wellnify AI — a platform fusing behavioral science and gamification to build healthy habits at the community level, not just the elite level.They get into the childhood roots of it all — dyslexia as a competitive advantage, a father's belief as rocket fuel, and sport as the only thing that ever cleared the noise. Travis is refreshingly honest about the entrepreneurial toll: from laying off 25 people after Intel scrapped a chip overnight, to throwing his house keys on the boardroom table to keep his team employed. And then the pivot — bringing tools once reserved for LeBron and Brady to municipalities, school boards, and everyday people across North America, including a landmark partnership with the Healthier Texas Foundation reaching 3,200 organizations.Takeaways:🧠 Dyslexia, ADHD, and slow processing forced Travis to think differently — and that became his edge. Pattern recognition, creative problem-solving, and deep listening aren't soft skills, they're the whole game.💡 The Pygmalion Effect is real — you rise or fall based on the expectations of the people around you. His father's belief in who he could become shaped everything.🏥 We're living in a healthcare paradox — the most advanced medical technology in history, and we're still witnessing what Travis calls a "self-inflicted serial killing" of our own wellbeing through sedentary behavior, screen addiction, and outdated wellness education.🏔️ Build fences at the top of the cliff, not more ambulances at the bottom — the trillion-dollar shift in healthcare is moving toward upstream prevention, and Wellnify AI is built entirely around that bet.🎮 Gamification isn't just for entertainment — Wellnify AI redirects the same mechanics that keep people scrolling toward movement, mindfulness, learning, and community acts of kindness.🤝 The most-used feature on the platform is the community section — rewarding users for volunteering, donating blood, picking up litter, and supporting local. People want to do good. They just need a structure that makes it stick.📊 The Community Wellness Score could change how governments measure what actually matters — aggregating individual data into a community-level metric that reveals blind spots and drives smarter public health investment.📱 Your attention is your life — Travis closes with a direct message to the 19–21 age group: the algorithm doesn't love you back. It's designed to capture, not to care. Knowing that is the first step. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 97: Beyond Insulin - Stem Cells, Islet Engineering, and the Future of Diabetes Care with Dr. Quinn Peterson

    In this episode, Dr. Jeremy Koenig sits down with Dr. Quinn Peterson, a Mayo Clinic stem cell biologist, to explore how regenerative medicine could move type 1 diabetes from lifelong management to true biological restoration.​✨ Key takeaways:🔥 From lab curiosity to purpose-driven science: how a cancer drug developer pivoted his entire career after his three-year-old daughter was diagnosed with type 1 diabetes, and later two more of his children.​🧬 Building transplantable islets, not just beta cells: inside the Mayo Clinic program engineering full pancreatic islets from stem cells to restore a person’s own insulin production.​🧠 Regeneration as the next medical era: why the future is not just fixing defective proteins but replacing missing cells and rejuvenating tissues before disease takes hold.​🤝 Science with patients at the table: how funders like Breakthrough T1D are forcing a shift toward patient and public involvement in shaping research questions and trial design.​📊 Data, digital twins, and AI: a candid look at breaking down clinical data silos, using wearables and records “in the wild,” and what that could mean for trials and personalization.​Episode overviewDr. Koenig introduces Dr. Quinn Peterson as a stem cell biologist and biomedical engineer at Mayo Clinic leading an islet regeneration program aimed at creating functional, transplantable pancreatic islets from pluripotent stem cells. Rather than simply managing glucose with exogenous insulin, Peterson’s work aims to restore lost biological function by engineering living systems that behave like native human tissue.​Quinn shares his origin story: a lifelong fascination with how things work, formal training in biochemistry, and early research careers in water contaminants and then chemotherapeutic drug development. The turning point came when his oldest daughter was diagnosed with type 1 diabetes at age three, eventually followed by two of his other children, prompting a deliberate pivot into diabetes research and postdoctoral training with Doug Melton at Harvard. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 96: Rewriting Medicine - Upstream Health, Multi‑Omics & AI with Dr. Helen Messier

    In this episode, Dr. Jeremy sits down with physician-scientist Dr. Helen Messier to unpack how multi-omics, AI, and “upstream medicine” are rewriting the future of healthcare—from managing chronic disease to truly preventing and reversing it.​🧠 Key takeaways:✨ You have more agency over your biology than you’ve been led to believe—your genes load the gun, but your environment, daily choices, and mindset pull (or don’t pull) the trigger.​🧬 “Upstream medicine” uses genomics, microbiome, metabolomics, proteomics, and more to find root causes instead of just chasing symptoms, especially in complex chronic conditions like chronic fatigue, IBS, and dysautonomia.​📉 The 15–20 year translational gap between research and the clinic is real, but platforms like BioScope.ai are closing it by turning massive, multi-layered data into usable clinical insight for front-line physicians.​⚙️ Your body isn’t broken; it’s adapting—traits that once protected us from famine and trauma can become maladaptive in a world of ultra-processed food, chronic stress, social media, and environmental toxins.​🏃‍♀️ The same systems thinking used to tune elite athletes’ training—acute vs. chronic load, HRV, recovery—can guide how families manage stress, sleep, and lifestyle across generations.​🧩 Mind and body are one system: psycho‑neuro‑immunology, childhood trauma, and epigenetics all shape how disease shows up decades later, and practices like meditation and nervous-system regulation can change gene expression and health trajectories.👨‍👩‍👧 True precision health is n-of-one: different people with similar genomes can need very different interventions depending on their environment, stressors, exposures, and life goals (performance vs. healthspan vs. longevity).​​ LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 95: When Ethics Meets Power: Stem Cells, AI, and the Future of Being Human with Dr. Insoo Hyun

    In this episode, we sit down with leading bioethicist Dr. Insoo Hyun to unpack how ethics, politics, AI, stem cells, and the future of human identity are colliding in real time—from embryo models and gene editing to digital twins and data ownership.✨ Key takeaways 🧬 How stem cell ethics, cloning, and embryo models really work behind the headlines—and why “the best argument” often loses to political feasibility. ⚖️ Why paying women for egg donation became a global flashpoint, and how one controversial Nature paper helped unlock pivotal advances in genome editing and mitochondrial disease research. 🤖 What “digital twins” mean for medicine, AI, and your health data—and why consent, ownership, and compensation will define the next era of scientific wellness. 🧠 How analytic philosophy (precision, logic, argument) can make sense of messy questions about consciousness, personhood, and transhumanism. 🌱 Why the future belongs to interdisciplinary thinkers who can bridge biology, ethics, AI, law, and policy—and how students like Kristin Lee can prepare for careers we can’t fully imagine yet.Episode overviewDr. Jeremy opens by asking whether the real risks in modern science are not rogue technologies, but the quiet assumptions we never question—about stem cells, AI, and biomedical breakthroughs shaped by politics, fear, and convenience. He introduces Dr. Insoo Hyun as a globally respected bioethicist whose work spans stem cell research, human–animal chimeras, brain organoids, embryo models, and the ethics of emerging biotechnologies.Hyun traces his unlikely path from pre‑med biology at Stanford, to switching into philosophy, to training in analytic ethics at Brown under Dan Brock—just as Dolly the sheep and human embryonic stem cells were transforming the life sciences. That timing pulled him into President Clinton’s bioethics commission, where he first saw how “political feasibility” can override the most rigorous ethical arguments. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 94: WellPro AI, Beyond 60-Page Reports - Building an Outcome-Native Health Operating System with David Lefkovits

    In this episode, Dr. Jeremy Koenig sits down with David Lefkovits, visionary CEO and co-founder of WellPro AI, to unpack why personalized, preventative healthcare hasn't scaled yet—and what it's going to take to finally get there. They dig into the broken economics of traditional medicine, why "normal" lab values don't always mean healthy, and how AI-powered systems can turn overwhelming data into actionable care plans that actually stick.🧬 Health isn't a static number—it's a dynamic conversation between hormones, nutrients, and lived experience that most practitioners aren't trained to read💰 Traditional healthcare thrives on worse outcomes—more encounters, more beds filled, more prescriptions written—while this emerging wellness economy ties revenue directly to results🔧 The biggest bottleneck isn't the science or the technology—it's the lack of an operating system that can turn insights into digestible, executable care plans📊 Most practices juggle 5-6 disconnected tools (EHR, scheduling, messaging, membership management) that don't talk to each other, creating operational chaos🎯 Patient goals and clinical goals aren't the same thing—someone wants more energy and time with their grandkids, not "take testosterone"🔄 Personalization is an oxymoron to protocols because everyone reacts differently to the same intervention—closed-loop tracking is non-negotiable⏳ The shift to outcome-based care is mathematically inevitable—costs keep rising, quality keeps dropping, and consumers will eventually migrate to where they get actual results🚀 WellPro isn't replacing clinicians—it's building a copilot that synthesizes chaotic patient data so practitioners can do what only they can do: see the patterns everyone else misses LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 93: From ICU to 100,000 Patients: Building the Future of Personalized Medicine

    In this episode, Chris Spears, founder of OrderlyMeds, shares his transformative journey from a catastrophic ICU experience to building a human-centered medication management platform that's revolutionizing personalized healthcare. Chris opens up about his frustrating odyssey through the broken healthcare system, the worst telemedicine experience of his life, and how those challenges sparked the creation of a company that's now serving over 90,000 patients monthly. This conversation explores the intersection of GLP-1 medications, DNA insights, AI-powered health data, and the future of precision medicine—revealing how one person's struggle became a mission to help millions thrive in the second half of life.Key Takeaways🏥 The healthcare system's blindness to patient experience created an opportunity for innovation—Chris transformed his worst customer service experience into a solution that now helps 90,000+ people manage their medication journey💉 GLP-1 medication shortages persist across America despite high demand—even two years later, many pharmacies still run out within days of receiving shipments🚀 Rapid scaling is possible with the right mission—OrderlyMeds grew from 17 customers in January 2024 to 60,000 monthly active patients by late 2025, adding 6,000-10,000 new patients each month🧬 DNA markers can predict GLP-1 response—genetic testing helps determine whether these life-changing medications will actually work for you before making the investment🔬 The future of healthcare is data integration—combining DNA, blood work, gut biome, wearable tech, and clinical data will enable truly personalized medicine at scale🤖 AI augments rather than replaces healthcare providers—technology can handle 80% of routine analysis, freeing humans to apply clinical judgment and compassion where it matters most💰 Financial investment drives adherence—cash-pay patients show higher medication compliance than insurance-covered patients, suggesting skin in the game matters for health outcomes👨‍👩‍👧‍👦 Building with friends and family creates accountability—surrounding yourself with trusted people who believe in your mission strengthens both culture and execution📱 Nine disconnected health apps create a new data problem—the next challenge is integrating fragmented health information into a single source of truth for consumers🎯 Personalized medicine requires personalized compounding—the future means your medication formulation will differ from others based on your unique biology⚡ Testosterone therapy remains stigmatized despite its benefits—only one in eight men who could benefit from testosterone replacement actually pursue it due to ego and shame🌟 Thriving in the second half of life is the real goal—weight loss and medication management are tools to help people keep up with grandkids, travel with partners, and enjoy life fully LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 92: From Monsanto to AI: Accelerating the Race Against Cancer with Dr. Chadi Nabhan

    In this episode, Jeremy Koenig sits down with Dr. Chadi Nabhan, a physician-scientist, oncologist, and healthcare innovator who stands at the intersection of cancer care, precision medicine, and artificial intelligence. Dr. Nabhan shares his remarkable journey from serving as a key expert witness in the landmark Monsanto Roundup trials to his current role as Chief Medical Officer at Right, where he's revolutionizing clinical trial design through AI. The conversation explores the critical importance of communication in healthcare, the challenges of translating complex science for patients and families, and how innovative technology is shortening the timeline for life-saving treatments to reach those who need them most.Key Takeaways🔬 From Courtroom to Page: Dr. Nabhan's book "Toxic Exposure" chronicles his experience as an expert witness in the Monsanto Roundup trials, revealing the science behind glyphosate's link to lymphoma and the drama of corporate litigation📚 Making Cancer Accessible: "The Cancer Journey" transforms complex oncology into relatable stories, guiding patients and caregivers through every step from diagnosis to treatment while honoring the often-overlooked role of caregivers⚡ Time is Lives: Clinical trials can take 10-15 years to complete, but even shortening this timeline by 2-3 years could save countless lives by bringing breakthrough therapies to market faster🎯 The 80% Problem: 80% of clinical trial sites run behind schedule, and 50% enroll zero or one patient—a massive inefficiency that Right is solving through AI-powered site selection🤖 Digital Twins Revolution: Right creates digital twins of every clinical trial site worldwide, matching protocols to the best-performing locations based on capabilities, patient demographics, investigator experience, and regulatory history💬 Language as Technology: Effective communication in healthcare means meeting people where they are—if a patient doesn't understand, it's the clinician's responsibility to communicate better, not the patient's failure to comprehend🎓 The Readiness Score: Just like Olympic athletes need specific fitness for their sport, clinical trial sites have unique readiness profiles for different studies—no single site is best for everything📖 Fiction Meets Truth: Dr. Nabhan's fourth book ventures into fiction, creating characters inspired by real experiences in academic medicine, demonstrating how storytelling can illuminate deeper truths🏥 AI and Cancer Care: His upcoming third book explores how artificial intelligence is transforming every aspect of the cancer journey, aiming to demystify AI and help people embrace rather than fear these innovations👥 Patient Voices Matter: The most powerful perspectives in healthcare innovation come from patient advocates who can bridge the gap between scientific advancement and lived experience LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 91: From Last Pick to Olympian - Why You're One of One with Eli Bremer

    In this episode, Dr. Jeremy Koenig sits down with Eli Bremer, Olympic modern pentathlete turned systems thinker and international sport leader, for a profound conversation about human performance, individualization, and the courage to reject one-size-fits-all approaches. From being picked last in childhood to competing at the Beijing Olympics, Eli shares his journey of discovering that success comes not from fixing weaknesses, but from exploiting strengths. They explore how DNA testing, AI, and personalized data are transforming athletic development, healthcare, and entrepreneurship—revealing that the future of performance isn't about optimization, but understanding. This conversation challenges conventional wisdom about talent, training systems, and what it truly means to be "one of one."Key Takeaways🏊 From Last Pick to Olympian - Eli's transformation from the kid picked last in kickball to Olympic athlete proves that persistence and self-belief can overcome initial limitations🧬 DNA Unlocks Decades of Discovery - Taking a genetic test revealed what Eli learned through 30 years of trial and error: his body responded best to higher volume training, validating his intuitive approach🎯 Systems vs. Individuals - The US Olympic system optimizes programs and recruits talent to fit them, while successful international programs optimize around each unique athlete🧠 The Intellectual Athlete - Athletes who think critically about their training, question systems, and actively participate in their development often become successful entrepreneurs and disruptors📊 Subjective Beats Objective - Despite advances in wearables and tracking technology, how an athlete feels often provides more valuable performance data than objective metrics alone💪 Exploit Strengths, Outsource Weaknesses - The best performers don't focus on fixing what they're bad at—they double down on what makes them exceptional and delegate the rest🔬 Soft Systems Over Hard Systems - Viewing athletes as complexities to understand rather than problems to engineer creates more sustainable, personalized pathways to excellence👨‍👩‍👧 Performance Beyond the Podium - Human performance extends from Olympic gold to making a child, raising a family, and building businesses—each requiring the same principles of understanding your unique design😔 Post-Olympic Depression is Real - Most Olympic athletes experience deep depression after competition ends, making identity beyond sport a critical but often overlooked aspect of athlete development🌟 You're One of One - Everyone has unique genetic advantages, life experiences, and strengths—success comes from discovering and embracing what makes you exceptional rather than trying to fit someone else's mold LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 90: The N of One Analyzer: Your Biology, Your Data, Your Health with Dr. Nathan Price

    In this episode of the DNA of Things, Dr. Jeremy Koenig welcomes back Dr. Nathan Price, co-director of the Center of Human Health Span at the Buck Institute and Chief Scientific Officer at Thorne. Dr. Price reveals how AI and multi-omic data are revolutionizing personalized medicine, transforming healthcare from reactive treatment to proactive wellness. He unveils his latest innovations—the N of One Analyzer and Health Span Horizons program—showing how your unique biological data can be translated into individualized interventions that extend healthspan.Key Takeaways🧬 AI-powered personalized medicine can now analyze your genome, microbiome, blood biomarkers, and lifestyle to create truly individualized health recommendations🤖 Dynamic health conversations replace static reports—ask follow-up questions and get contextualized insights tailored to your specific biology and goals🔬 Health Span Horizons launches two breakthrough tools: Health Span Compass (personal advice engine) and Health Span Synthesizer (autonomous AI research system)💡 Everyone is an N of One—your unique combination of genetics, environment, and lifestyle requires personalized rather than one-size-fits-all approaches⏱️ AI accelerates discovery—what took researchers 1-3 years can now be analyzed and reported in real-time🎯 Participatory health empowers you to become the scientist of your own life using AI and dense biological data🚀 Healthspan extension is proven—the years you live healthy and happy are definitively extendable through screening, lifestyle optimization, and emerging therapeutics LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 89: Decoding Women's Health Through Systems Biology and AI with Dr. Elena Ikonomovska

    In this episode, Dr. Jeremy Koenig sits down with Dr. Elena Ikonomovska, a machine learning scientist and co-founder/CEO of Diadia Health, to explore how artificial intelligence and systems biology are revolutionizing women's health. Elena shares her journey from building algorithms at tech giants like Google and Reddit to turning her expertise inward when conventional medicine failed to address her own health struggles. She reveals how normal lab ranges often conceal systemic disease, especially in women, and introduces a groundbreaking approach that analyzes the dynamic interplay between hormones, immunity, and metabolism to enable precision prediction and personalized healing.Key Takeaways🧬 Standard lab ranges are misleading – Normal TSH levels can hide low T3 thyroid hormone levels in 75% of women, leading to missed diagnoses and years of suffering🔗 Systems biology reveals hidden connections – Health issues like hypothyroidism, insulin resistance, and nutrient deficiencies don't exist in isolation but interact in complex patterns that traditional medicine overlooks🤖 AI-powered precision health – Machine learning can decode the relationships between biomarkers, genetics, symptoms, and lifestyle factors to create personalized health optimization strategies🎯 Individual optimal ranges matter – Standard lab ranges reflect the status quo of an unhealthy population; true health requires targeting your unique optimal ranges based on genetics and health history💪 Women must become health advocates – Comprehensive testing of thyroid, sex hormones, metabolism, and immunity at least twice yearly, combined with data-driven insights, empowers women to demand better care🔬 Genetic context transforms biomarker interpretation – Understanding genetic variants (like DIO2 for thyroid conversion) explains why the same lab values mean different things for different people🌟 Functional medicine meets technology – Diadia Health combines expert functional medicine knowledge with AI analysis to fill gaps in women's health research and create actionable protocols📊 Continuous monitoring enables experimentation – Regular biomarker testing every three months allows for hypothesis testing and discovery of what interventions actually work for your unique biology🧘 Trauma impacts physiology – Immune dysfunction, histamine reactions, and mast cell activation can stem from traumatic events, requiring both biological support and trauma healing🚀 Citizen science is the future – Taking ownership of health data and participating in collaborative research helps build better datasets and optimal ranges for women's health preventionAbout the GuestDr. Elena Ikonomovska is a machine learning scientist with a PhD in artificial intelligence and the co-founder and CEO of Diadia Health, a precision health company reimagining women's health through systems biology and data intelligence. Before founding Diadia Health, Elena built algorithms that powered decision systems at Google, Reddit, and Change.org. She has also worked in blockchain technology focusing on real-time spam and scam detection. Her work unites data science with empathy to decode the dynamic interplay between hormones, immunity, and metabolism, revealing new pathways toward understanding and healing in women's health. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 88: Building Healthcare's Missing Infrastructure with Pouria Sanae

    In this episode, Dr. Jeremy Koenig sits down with Pouria Sanae, CEO and co-founder of ixlayer, to explore the transformation of healthcare delivery through technology and systems thinking. Pouria shares his remarkable journey from aerospace engineering to becoming a pioneer in precision medicine infrastructure, driven by a profound realization about the fragmented nature of modern healthcare after witnessing a 37-year-old patient's devastating Alzheimer's diagnosis.The conversation delves into how ixlayer is rebuilding healthcare's fundamental architecture by connecting labs, clinicians, payers, and patients into seamless diagnostic journeys. From processing 90,000 COVID tests daily with a 20-person team to enabling direct-to-patient experiences across cardiology, oncology, and Alzheimer's care, Pouria reveals the critical infrastructure layer that makes precision medicine accessible and actionable.Key Takeaways🎯 The Pre-Patient Revolution - Healthcare must shift from reactive treatment to proactive screening, catching disease before symptoms appear rather than waiting for the "check engine light" to activate🔬 The Single Pixel That Changed Everything - A 37-year-old patient with 95% probability of early-onset Alzheimer's at age 45 became the North Star for ixlayer's patient-centered design philosophy🏗️ Infrastructure Over Innovation - The most important healthcare technology isn't a new drug but the seamless infrastructure that connects patients to testing, diagnosis, and treatment📊 Beyond Normal Ranges - Traditional lab result "normal ranges" are statistical averages that ignore individual optimization, age, geography, and personal health goals🌉 Bridging Healthcare Islands - Patients currently face disconnected "islands" (symptoms, doctors, labs, prescriptions) with no bridges between them; ixlayer creates those connections⚡ The 0.08% Problem - Only 0.08% of patients who see a pharmaceutical ad actually reach a prescription, taking 3-7 months navigating a friction-filled system🔗 Shopify Meets Stripe for Healthcare - ixlayer combines patient experience design (like Shopify) with clinical service integration (like Stripe) to orchestrate complex multi-vendor healthcare journeys🧬 From Helix to Healthcare Scale - Early genomics work at Helix revealed that every organization was rebuilding the same infrastructure wheel, leading to ixlayer's platform approach🚀 COVID Stress Test - Processing 1,100 programs and 90,000 daily tests during the pandemic forced rapid scaling and proved the platform's resilience at extreme volume💡 Don't Wait Philosophy - The most critical health intervention is taking action today rather than postponing preventive care, testing, or lifestyle changes until tomorrow LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 87: Your Biology Listens: How Epigenetics and Microbiome Science Are Revolutionizing Personalized Health with Dr. Neal Kitchen

    In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Dr. Neal Kitchen, COO of Epimorphy and pioneer in personalized health through epigenetics and microbiome integration. As an identical twin with a divergent health journey from his brother, Neal offers a unique perspective on how biology responds to our choices rather than dictating our fate. This conversation explores the intersection of genetics, epigenetics, and the microbiome, revealing how scientific wellness platforms like Liv by Epimorphy are transforming complex biological data into actionable insights for everyday people.Key Takeaways:🧬 Your DNA isn't a fixed blueprint but a dynamic listener that responds to your environment, lifestyle choices, and daily habits—making biology a dialogue rather than destiny👯 Identical twins with the same genetic code can have vastly different health outcomes, proving that epigenetics and microbiome diversity play crucial roles in shaping who we become🎹 Think of genetics as piano keys and epigenetics as the music you play—the keys are fixed, but the melody changes based on how you interact with your biology🔬 Liv by Epimorphy integrates three critical layers of personalized health: genetics (your inherited code), epigenetics (how lifestyle modifies expression), and microbiome (your microbial ecosystem) to create comprehensive wellness insights💑 Vaginal and semen microbiome testing can optimize not just fertility but long-term intimate relationships by understanding microbial exchange between partners⚡ Biological interventions can produce surprisingly rapid changes when properly targeted—your body responds faster than you think when given the right information🎯 Women's health has been historically underserved in clinical research, with women often treated as "small men" in studies, making sex-specific health platforms essential for accurate personalization📊 Continuous monitoring creates living biological models that reveal patterns invisible in one-time snapshots, transforming how we understand metabolic responses and health trajectories🔄 The future of personalized medicine requires longitudinal data integration from wearables, lab tests, and molecular sequencing to build truly actionable health narratives🌊 Moving from fearing your data to conversing with it represents a fundamental shift in health consciousness—understanding that measurements are invitations for evolution, not judgmentsInstagram: https://www.instagram.com/livwomen.us?igsh=NTc4MTIwNjQ2YQ==Check their website: livbio.com Music from #UppbeatLicense code: OUWYN8VSSNKJRVME LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 86: From Lab to Kitchen: Ancestral Microbiome Science with Dr. Jens Walter

    In this episode, Dr. Jeremy Koenig sits down with Dr. Jens Walter, a global leader in microbiome research and professor at University College Cork Ireland, to explore how ancestral dietary patterns can reverse metabolic imbalances and restore gut health. Dr. Walter shares groundbreaking insights from his NiME Diet trial, which demonstrated substantial improvements in cardiometabolic risk markers, increases in neuroprotective metabolites, and reductions in carcinogenic compounds—all achieved in just three weeks using affordable, practical supermarket foods. The conversation traverses the evolution of microbiome science, the economics of healthy eating, the role of food processing in modern society, and why top-down systemic change is essential to close the gap between what's biologically possible and what people actually eat.Key Takeaways🔬 Remarkable Biomarker Changes in 3 Weeks: Dr. Walter's NiME Diet trial showed substantial improvements in cardiometabolic risk markers, neuroprotective metabolites like indole-3-propionate, and reductions in carcinogenic compounds🥗 Affordable, Practical Foods Work: The NiME Diet uses normal supermarket foods—no exotic or expensive ingredients required—proving that microbiome restoration is accessible🦠 Microbiome Disruption Drives Modern Disease: The shift from ancestral to industrialized diets has disrupted our ancient symbiosis with gut microbes, contributing to skyrocketing chronic disease rates📊 The Longevity Connection: Large-scale epidemiological studies show that sustained dietary patterns built on principles similar to the NiME Diet can add up to a decade of healthy life expectancy💰 Economics Trump Health: Food companies operate in a capitalistic system where even 3-5 cents price difference determines viability, making it nearly impossible to produce healthy foods without systemic change🏛️ Top-Down Reform Is Essential: Individual effort alone won't solve the health crisis—successful interventions like Finland's nutrition program in the 1960s required political, systematic overhaul of food systems🍽️ Practical Implementation: Through partnership with Gourmet Fuel in Dublin, Dr. Walter is translating microbiome science into daily life with cost-effective, ancestral-inspired meals🌍 Ecological Thinking: Understanding microbiomes requires viewing them as complex ecosystems where organisms interact synergistically and competitively, with selection acting at multiple levels🧪 Food Processing Isn't Evil: Not all processing is harmful—frozen and canned vegetables retain nutritional value, and the focus should be on making processed foods healthier rather than eliminating them LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 85: 80% of Disease is Preventable: Why Your Doctor Can't See It Coming with Guy Leitersdorf

    Dr. Jeremy Koenig sits down with Guy Leitersdorf, founder and CEO of Longevity AI, for a powerful conversation about transforming healthcare from reactive to proactive. After losing his father to late-stage lung cancer despite premium healthcare monitoring, Guy left his role as a data scientist at IronSource to build Florence—an AI system that analyzes decades of longitudinal medical data to predict and prevent chronic disease.Drawing from the same behavioral science techniques used to predict consumer clicks, Guy discovered that 80% of unhealthy years are preventable through early intervention in metabolic, cognitive, heart, and immune health. Today, Longevity AI partners with leading healthcare networks including Genics, Well Health Technologies, and Quadrant Management, reaching toward 200,000 practitioners to deliver personalized longevity plans that save doctors 50% of their time while empowering patients with actionable, evidence-based health guidance.Key Takeaways🔬 80% of chronic disease burden is preventable through early detection of patterns in metabolic, cognitive, heart, and immune health—the "four horsemen" of aging🤖 Florence AI analyzes millions of patient records across decades to identify health trends that traditional point-in-time assessments miss, turning longitudinal data into personalized prevention strategies💡 The same technology that predicts consumer behavior can be repurposed to predict health outcomes—Guy applied lessons from advertising AI to build predictive health intelligence⚕️ Clinical-grade biological age assessments provide more meaningful health insights than chronological age, measuring metabolic, immune, cognitive, and cardiovascular function separately🎯 Personalized health coaching works like "Tinder for habits"—matching evidence-based interventions with activities people actually enjoy, dramatically increasing adherence⏱️ Longevity AI's platform saves physicians over 50% of their time by synthesizing complete patient health pictures, enabling doctors to focus on high-value clinical decisions🔒 Privacy-first AI architecture processes health data on-device, never exposing sensitive clinical and lifestyle information to external servers🌍 Tailored biological ages account for regional differences—the same biomarker readings can indicate different health states depending on location, air quality, food systems, and standards of care🏥 Strategic partnerships with 200,000+ practitioners position Longevity AI to deliver 10 billion additional healthy years by making prevention accessible at scale💪 Longevity is a decision—taking one evidence-based healthy action in 2026 can compound into years of extended healthspan LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 84: The Biology of Belief: How Consciousness Shapes Your Genes with Dr. Garrett Yount

    In this episode of the DNA of Things, host Dr. Jeremy Koenig sits down with Dr. Garrett Yount from the Institute of Noetic Sciences to explore the fascinating intersection of consciousness, biology, and human potential. They dive deep into how our thoughts, emotions, and intentions can literally reshape our gene expression and physical reality—without any genetic engineering or technological augmentation. Dr. Yount shares the science behind "vibes," the power of heart coherence, and introduces his new course on energy awareness that teaches practical techniques for influencing your own biology through mindfulness and attention.Key Takeaways🧬 Your mind is in constant conversation with your genes—what you focus on and how you feel can trigger epigenetic changes that either heal or harm your body🧘 The placebo effect demonstrates pure mental events changing gene expression, with studies showing the brain producing endogenous opioids simply through belief❤️ Your heart generates the strongest electromagnetic field in your body, extending three feet outward, and its signature changes based on your emotional state—gratitude versus anger creates measurably different frequencies🔬 The Institute of Noetic Sciences merges rigorous scientific methodology with consciousness research, studying phenomena like external Qigong's effects on cells and the biological impact of meditation🎯 Athletes and high performers intuitively understand mind-body coherence—Dr. Koenig shares how he went from 700th to 7th in national rankings in just three months through coached awareness practices📱 Modern technology and social media are constantly programming our biology through attention hijacking—reclaiming conscious control of what influences your mind is radical self-care🌡️ Simple self-tests like the hand warming exercise prove you can direct blood flow through focused attention, demonstrating immediate mind-body influence anyone can experience🧪 Transgenerational epigenetic inheritance from events like the Dutch Hunger Winter shows how trauma and stress create methylation patterns that persist for generations💡 True transhumanism may not require external technology—untapped powers of human consciousness and intentional practices offer an internal path to enhancement🎓 Dr. Yount's new course offers eight modules of practical training in sensing and regulating your energetic body, complete with scientific context and experiential practices for beginners LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 83: CENEGENICS: Tailored Longevity for All Ages with Kristy Berry

    In this episode, Dr. Jeremy Koenig sits down with Kristy Berry, CEO of CENEGENICS, to explore how longevity medicine evolved from a “fringe” idea to the future of proactive health. Kristy’s story—from her start as the company’s first patient service associate to leading a global network redefining human performance—illustrates what it truly means to take ownership of your health and longevity. Together, they dive into how CENEGENICS blends cutting-edge science with human connection, reshaping healthcare from treatment to transformation through precision diagnostics, AI-driven longevity platforms, and a deep understanding of each patient’s unique biology.✨ Key Takeaways 💪 From fringe to future: Once viewed skeptically, longevity medicine is now seen as the next frontier of healthcare—CENEGENICS was simply early, not wrong. 🧬 Personalized, data-driven care: The company’s holistic approach integrates nutrigenomics, biomarker analysis, and musculoskeletal AI scans to create actionable health insights. 🧠 Technology meets empathy: Kristy emphasizes that while data guides care, human connection is what transforms it. 🌍 Longevity for everyone: What was once an elite concept is now essential—CENEGENICS’ mission is to make proactive health accessible to all ages and lifestyles. 🏃‍♀️ Empowerment through awareness: True wellness starts with understanding your body and taking charge of your health narrative—becoming the CEO of your own body. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 82: Dr. Lee Hood on Systems Biology, P4 Medicine, and the Future of Health

    In this episode, Dr. Lee Hood, one of the great pioneers of modern biology, joins Dr. Jeremy Koenig for an in-depth conversation about the evolution of medicine—from reactive care to predictive, preventive, personalized, and participatory (P4) health. Known for developing the automated DNA sequencer and co-founding Amgen, Dr. Hood traces eight paradigm shifts that revolutionized biology and healthcare, from systems biology to data-driven wellness. He shares how integrating big data, AI, and human behavior can unlock early detection, extend health span, and empower individuals to become true masters of their health. This episode explores not just the science behind wellness but the human, institutional, and ethical changes needed to make it real.✨ Key Takeaways: 🧬 Systems Thinking — Health must be viewed as an interconnected network, not isolated organs or symptoms. 💡 Eight Paradigm Shifts — From engineering biology to creating peptide-based drugs, Dr. Hood outlines the milestones that transformed medicine into an information science. 📊 Data-Driven Health — Using genomics, proteomics, and behavioral data to identify actionable insights that prevent disease and optimize wellness. 💪 P4 Medicine — Predictive, Preventive, Personalized, and Participatory healthcare represents the future of medicine. 🤖 AI & Knowledge Graphs — Artificial intelligence will help physicians become domain experts across all fields and personalize patient care like never before. 🧠 Participatory Health — Individuals must actively engage with their data, making prevention and wellness a personal mission. 🌍 Systems Biology Beyond Medicine — Dr. Hood believes systems thinking could reshape politics, economics, and education to foster collective well-being.#SystemsBiology #DataDrivenHealth #P4Medicine #PredictiveMedicine #PreventiveMedicine #PersonalizedMedicine #ParticipatoryHealth #ScientificWellness #PrecisionHealth #Genomics #AIinMedicine #HealthcareInnovation #FutureOfMedicine #HealthTech #WellnessRevolution #PhenomeHealth #BiotechInnovation #HumanHealth #MedicalScience #DrLeeHood #TheDNAofThingsPodcast #JeremyKoenig LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 81: Designing the Future of Medicine: Dr. Don Brown on AI, Genomics, and Precision Health

    In this episode of The DNA of Things, Dr. Jeremy Koenig welcomes Dr. Don Brown — physician, entrepreneur, software visionary, and founder of Bioscope — to explore how technology, AI, and genomics are reshaping the future of precision medicine. From his early studies in biochemistry and computer science to leading billion-dollar tech companies, Dr. Brown shares his inspiring journey of merging data visualization, healthcare, and human compassion. Together, they discuss the power of AI-driven synoptic dashboards for doctors, the democratization of health data, and the coming revolution in longevity and personalized care. The conversation dives into how Bioscope integrates genomics, microbiome data, and AI to help clinicians interpret health in real time — turning raw information into actionable insights for both doctors and patients.✨ Key Takeaways: 🧬 Precision medicine is shifting from reactive care to predictive and personalized health. 💡 AI and genomics are empowering doctors to see “health in motion” with real-time dashboards. 🚀 The cost of whole genome sequencing has dropped dramatically, accelerating accessibility. 🧘‍♂️ Movement, mindfulness, and longevity science go hand in hand in extending healthspan. 🌍 Democratizing healthcare technology is key to creating global access and impact.#PrecisionMedicine #AIinHealthcare #Genomics #LongevityScience #HealthTech #FutureOfMedicine #Bioscope #DrDonBrown #TheDNAofThings #DrJeremyKoenig LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 80: Your Health, Your CEO Moment: Taking Charge in the Age of Digital Medicine with Eliad Josephson

    In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Eliad Josephson, a Wall Street banker turned Hollywood financier and now diagnostics industry leader, to explore how the healthcare system is undergoing a radical transformation. Together, they discuss how diagnostics, preventative care, and digital health innovations are reshaping the future of medicine—putting patients at the center as the CEOs of their own health. Eliad shares his remarkable journey from finance to film to healthcare, revealing how relationships, leadership, and technology converge to create a more proactive, patient-empowered system. From AI’s growing role in diagnostics to the democratization of data through at-home testing, this conversation unpacks the seismic reset happening in modern medicine and what it means for the future of longevity and wellness.💡 Key Takeaways: ✨ Healthcare is undergoing a massive reset driven by technology, patient empowerment, and preventative diagnostics. 💼 Eliad’s multidisciplinary background—from Wall Street to Hollywood—illustrates how innovation and relationships drive transformation. 🧬 The rise of AI and at-home testing tools is enabling patients to take control of their health like never before. 🔗 Diagnostics and preventative care are moving to the forefront, shifting medicine from reactive to proactive. ⚙️ The future of healthcare depends on integrating data from genetics, wearables, and labs into unified platforms. 🌍 A healthier system begins at home—through awareness, education, and early adoption of diagnostic tools. 👩‍⚕️ Eliad’s message: we are the experts in our own bodies, and it’s time to take charge of our health future. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 79: AI, Adaptability, and the Founder’s Journey with Matt Cooper of Volta

    In this episode, Dr. Jeremy Koenig sits down with Matt Cooper, CEO of Volta, one of Canada’s largest innovation hubs, to explore how curiosity, discipline, and first principles thinking shape resilient founders and thriving ecosystems. With over two decades of entrepreneurial experience, Matt shares his journey from building software and scaling startups to leading a community of innovators in Atlantic Canada. Together, they discuss how modern founders can leverage AI, reduce the cost of failure, and stay close to unmet needs to drive progress. Matt emphasizes treating “product as a promise” and “founders as learners,” revealing why adaptability, empathy, and curiosity matter more than ever in today’s startup landscape.✨ Curiosity is the ultimate advantage — the most successful founders are lifelong learners. 🚀 The barriers to entry have never been lower — AI allows entrepreneurs to test, build, and scale faster than ever. 💡 Treat your product as a promise, not a feature — deliver value that creates real progress for others. 🌍 Ecosystems rise when individuals commit — mentorship, community, and shared purpose fuel sustainable growth. 🧭 Stay close to the unmet need — assume you’re wrong, reduce the cost of learning, and build with humility. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 78: DNA, Behavior, and Relationships: The Real Keys to Healthspan

    In this episode of The DNA of Things, Josh Bowerman, co-founder and managing director at JB Andrews, takes the host seat to interview molecular biologist and entrepreneur Dr. Jeremy Koenig. Together, they explore the science and business of longevity, diving into how genetics, behavior, and practical systems can help extend not just lifespan but healthspan. From elite athletes to entrepreneurs and families, Jeremy shares first principles thinking on performance, relationships, and sustainable health strategies. Discover why small trim-tab choices compound over time, how to systematize routines to thrive across careers and parenthood, and why relationships may be the most critical pillar of long-term vitality.✨ Key takeaways: 🧬 Healthspan vs. lifespan — why quality of life matters more than raw years. ⚡ Small daily choices compound into long-term performance and longevity. 🏃 Lessons from athletes and entrepreneurs that apply to everyone. 🌍 Longevity through three pillars: athletics, business, and family. 🤝 Relationships as the foundation of a meaningful human experience. 💡 Practical tools: systematize your routines to stay prepared under pressure. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 77: Beek Health and Beyond: How Data Empowers Patients to Take Control with Brent Dial

    In this episode of The DNA of Things, host Dr. Jeremy Koenig sits down with Brent Dial, founder of Beek Health, to uncover the hidden architecture of healthcare and how data, diagnostics, and human behavior intersect to empower individuals in their health journeys. From his transition as a finance leader to a healthcare innovator, Brent reveals the inefficiencies and barriers that keep life-saving tools out of patients’ reach and explains why shifting from reactive sick care to proactive healthspan management is critical. He shares how platforms like Beek Health are simplifying data, bridging fragmented systems, and giving people the knowledge to make informed decisions about their biomarkers, risk factors, and long-term health.✨ Why the current healthcare system creates confusion and delays 💡 The role of biomarkers in predicting and preventing disease 🧠 How individual empowerment can transform healthcare decisions 🔬 The vision of proactive diagnostics versus reactive medicine 🌍 Why health should become as much a cultural conversation as sports or finance LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 76: Beyond the Peak: How Athletes Transition Into Entrepreneurship with Jaco Burger

    In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with Jaco Burger—entrepreneur, elite performance coach, and Chief Innovation Officer at Volta Innovation Hub—to explore how the mindset of an athlete mirrors that of an entrepreneur. From his early dream of becoming a professional cricket player to coaching ATP tennis pros, and now guiding founders and athletes through Beyond the Peak, Jaco shares his journey of resilience, transition, and human-centered innovation. Together, they dive into the parallels between high-performance sport and entrepreneurship, the challenges of identity beyond the game, and how athletes can channel their discipline, focus, and resilience into building impactful ventures.Key Takeaways:✨ The athlete’s mindset—discipline, resilience, and adaptability—is the DNA of entrepreneurship. 🔄 Transitioning from sport to business requires an identity reset and skills reframe. 🌍 Building community and cultivating human connection are vital for founders’ success. 💡 Entrepreneurship is about solving problems with creativity, not just chasing opportunity. 🚀 Beyond the Peak empowers athletes to harness their performance mindset for life after sport. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 75: Feeding Your Microbes: Why Gut Diversity Shapes Longevity with Dr. Sean M. Gibbons

    In this episode of The DNA of Things, Dr. Jeremy Koenig is joined by Dr. Sean Gibbons, systems biologist and computational microbiome researcher at the Institute of Systems Biology in Seattle. Together, they dive into the fascinating world of the human gut microbiome, tracing its role from shaping the planet billions of years ago to influencing our health, immunity, and even emotions today. Dr. Gibbons shares his journey from studying microbial ecology to creating My Digital Gut, a cutting-edge simulation platform that predicts how individual microbiomes respond to diet and interventions. This conversation unpacks the promise of personalized nutrition, the ethical challenges of microbiome research, and why cultivating microbial diversity may be key to resilience and longevity.✨ Key Takeaways🌍 Microbes are Earth’s original architects, shaping ecosystems for billions of years🧬 The gut microbiome holds more genes than the human genome, influencing metabolism, immunity, and behavior🍎 My Digital Gut simulates how dietary changes affect individual microbiomes for personalized health insights🧪 Short-chain fatty acids like butyrate play a crucial role in reducing inflammation and supporting metabolic health🥦 Dietary diversity fuels microbial diversity, boosting resilience and pathogen resistance🚀 The future of health may lie in precision probiotics and tailored nutrition guided by microbiome science LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 74: Healthspan Over Lifespan: How NOVOS Is Redefining Aging with Science with Dr. Diogo Barardo

    In this episode of The DNA of Things, Dr. Jeremy Koenig sits down with longevity scientist Dr. Diogo Barardo to explore how science is reshaping the way we understand aging, healthspan, and vitality. From his early shift from physics to biology to leading groundbreaking research at NOVOS, Dr. Barardo reveals how biological age clocks, data-driven interventions, and ethical science are paving the way to compress the sick years and expand our healthiest years of life. Together, they dive into the logic of aging, the pitfalls of DIY supplement stacking, the promise of biological aging clocks, and the future of personalized health interventions backed by real data.✨ Key Takeaways:🔬 Why targeting aging itself could prevent multiple chronic diseases at once⚖️ The truth about supplement synergy — why more isn’t always better🧬 How biological age clocks provide a clearer picture than chronological age🧪 The role of epigenetics, proteomics, and multi-omics in tracking longevity🌍 Why closing the healthspan-lifespan gap is both a scientific and ethical imperativeThis conversation is more than a glimpse into cutting-edge longevity research — it’s a call to action for individuals, policymakers, and innovators to rethink how we approach health, prevention, and the future of aging. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 73: The Symphony of Aging: Dr. Raghav Sehgal on Epigenetic Clocks & Longevity

    In this episode, Dr. Jeremy Koenig sits down with Dr. Raghav Sehgal, a Yale-trained computational biologist and longevity researcher, to uncover the science behind aging, resilience, and the future of preventative medicine. From his unconventional journey starting in electronics engineering in India to pioneering breakthroughs in epigenetic clocks and system-specific biomarkers of aging, Dr. Sehgal reveals how technology, biology, and proactive healthcare intersect to redefine longevity. Together, they explore how aging is not a single timeline but a complex symphony across 11 bodily systems, why resilience is as important as lifespan, and how interventions—from intermittent fasting to personalized medicine—can reshape healthspan. The conversation also dives into the limitations of reactive healthcare, the role of big pharma, and the promise of proactive, precision-based longevity science. Whether you’re a biohacker, physician, or someone curious about living not just longer but better, this episode offers insights into the future of aging research and human flourishing.✨ Key Takeaways:🧬 Aging is not one clock—it’s 11 interconnected systems that can be tuned like instruments. 🩺 Moving from reactive medicine to proactive longevity science is the key to healthier lives. 💊 Epigenetic clocks reveal how interventions like Ozempic and lifestyle changes target specific organ systems. ⚡ Resilience—your body’s ability to bounce back—is a stronger predictor of healthy aging than years alone. 🤝 Social connections and mental health are just as critical as diet, exercise, and sleep for longevity. 🥗 Intermittent fasting, diverse exercise, and preventative care are simple but powerful tools for better healthspan. 🌍 The future of medicine may include longevity clinics, personalized dashboards, and even gamification of aging. LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 72: How Insurance Companies Are Using Epigenetics to Help You Live Longer with Tom Nodine

    In this episode, we dive deep into the groundbreaking intersection of epigenetics, insurance innovation, and human longevity with Tom Nodine, a trailblazer who's transforming how insurers approach health and wellness. Tom shares his journey from traditional insurance consulting to pioneering epigenetic testing applications that could help people live longer, healthier lives while creating win-win scenarios for both insurers and policyholders.We explore how epigenetic clocks can measure biological age versus chronological age, the potential for reversing aging at the cellular level, and why this technology represents one of the most significant opportunities in healthcare and insurance. This conversation challenges conventional thinking about aging, health optimization, and the future role of insurance companies in proactive wellness.🔑 Key Takeaways🧬 Epigenetics Revolution: Unlike genetics (your unchangeable DNA code), epigenetics shows how your behaviors and environment can actually change gene expression and biological aging⏰ Biological Age vs Chronological Age: Epigenetic testing can reveal whether you're aging faster or slower than your calendar age - and help you reverse it🏥 Insurance Innovation: Life insurance companies can now partner with customers to help them live longer through epigenetic monitoring and targeted interventions📊 Measurable Results: Early studies show 3-year biological age reduction in just 8 weeks with proper interventions🎯 80/20 Rule: Genetics only account for ~20% of longevity - the other 80% comes from behaviors and environment you can control🔬 Beyond Gaming: This isn't just biohacking - it's serious science with applications in underwriting, fraud detection, and personalized medicine⚡ Intervention Tracking: For the first time, we can quantitatively measure which diet, exercise, or lifestyle changes work best for individual people🚀 Future Vision: Scientists believe we may be able to reset cellular aging through epigenetic maintenance, potentially extending healthy lifespan significantly💊 Drug & Supplement Testing: Epigenetic testing could revolutionize how we prove effectiveness of pharmaceuticals and nutraceuticals🌍 Global Health Impact: This technology works via mail-in saliva tests, making it accessible for countries with limited healthcare infrastructure LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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    Episode 71: Kick Sciatica Out of Your Life: Dean Volk’s Proven Pain Relief Method

    In this episode of The DNA of Things, host Dr. Jeremy Koenig sits down with Dean Volk, a dedicated sciatica relief expert and founder of Sciatica Relief Now, to uncover a groundbreaking, non-invasive approach to eliminating sciatic nerve pain without medication, injections, or surgery. Dean shares how a sudden health crisis in his family led to the development of his unique, highly effective methods that have helped thousands reclaim a pain-free life. From debunking outdated “generic” exercises to explaining why working the opposite side of the body can unlock healing, this conversation dives deep into the science, personal stories, and actionable strategies for long-term relief. Whether you’re an athlete, desk worker, or someone who’s struggled with chronic pain for years, Dean’s holistic, body-balancing approach offers a fresh path to recovery.Key Takeaways: ✨ Why most traditional sciatica treatments fail and how Dean’s method flips the script 💡 The surprising role of the opposite side of the body in pain relief 🧠 How balancing the body calms the nervous system and accelerates healing 🏃‍♂️ Real-world success stories—from marathon runners to chronic pain sufferers 🛑 Why surgery should be your last resort for sciatica reliefIf you’ve tried everything for your back or leg pain and nothing has worked, this episode may just change the way you think about recovery forever.https://sciaticareliefnow.net/ LINKS:https://www.drjeremykoenig.com/https://www.instagram.com/drjeremykoenig/https://www.youtube.com/@drjeremykoenigHere's the link for this week's episode: https://drjeremykoenig.substack.com/.

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ABOUT THIS SHOW

The DNA of Things," hosted by Dr. Jeremy Koenig, is an auditory journey into the evolving world of health science, performance, and longevity. This podcast brings together the sharpest minds in the field, including elite health strategists, pioneering scientists, and wellness mavericks, to share cutting-edge practices and revolutionary insights. Each episode is meticulously curated to enrich your understanding of well-being and to extend your vitality, propelling you toward a future filled with possibilities. Join Dr. Koenig as he unveils the secrets of human potential through the lens of genomics, and discover how to transform your health and life trajectory.

HOSTED BY

Dr. Jeremy Koenig

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The DNA of Things with Dr. Jeremy Koenig currently has 50 episodes available on PodParley. New episodes are automatically indexed when they're published to the podcast feed.

What is The DNA of Things with Dr. Jeremy Koenig about?

The DNA of Things," hosted by Dr. Jeremy Koenig, is an auditory journey into the evolving world of health science, performance, and longevity. This podcast brings together the sharpest minds in the field, including elite health strategists, pioneering scientists, and wellness mavericks, to share...

How often does The DNA of Things with Dr. Jeremy Koenig release new episodes?

The DNA of Things with Dr. Jeremy Koenig has 50 episodes. Check the episode list to see recent publication dates and frequency.

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Who hosts The DNA of Things with Dr. Jeremy Koenig?

The DNA of Things with Dr. Jeremy Koenig is created and hosted by Dr. Jeremy Koenig.
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