PODCAST · health
Wysdom Radio™
by Wysdom
We deliver short, focused episodes on the main concepts and procedures you actually need to know. It’s the perfect clinical companion for your drive to work or your daily workout. Come learn IR on the go!Check us out at https://www.medicalwysdom.ai/
Episodes
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Ablate (RFA) and Stabilize (Cement): OsteoCool RFA for Painful Bone Metastases, with Dr. Jason Levy (OPuS One)
This masterclass episode breaks down OPuS One, the prospective, multinational study of OsteoCool radiofrequency ablation (RFA) plus cement for painful lytic metastases of the spine and pelvis. Following, there is an expert commentary by Dr. Jason R. Levy of Northside Hospital, Atlanta. The…
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EMMY at 10 Years: Two-Thirds Avoid Hysterectomy
This fundamentals episode breaks down the 10-year results of the EMMY trial, the Dutch randomized comparison of uterine artery embolization (UAE) versus hysterectomy for symptomatic uterine fibroids, and the longest randomized follow-up of the two treatments reported so far. Following, there is…
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Beyond the Drug: What Makes TACE Work?
This episode breaks down PRECISION V, the 2010 randomized trial that helped make drug-eluting beads a standard option for hepatocellular carcinoma (HCC), and tests its conclusions against later bland-bead and anatomy data. Following, there is an expert commentary by Dr. Premal Trivedi, Chief of...
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Infra-popliteal Bioresorbable Stents: The NEJM LIFE-BTK Trial
This episode breaks down LIFE-BTK, the 2024 New England Journal of Medicine randomized trial testing whether a drug-eluting resorbable scaffold beats plain balloon angioplasty for infrapopliteal artery disease in chronic limb-threatening ischemia. The Premise: Below the knee has been a graveyard…
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Fractured IVC Filter Fragments: The Penn Perspective
This episode features expert commentary from Dr. Scott Trerotola of Penn Medicine, responding to our recent episode on Stanford's fractured IVC filter registry titled, Fractured IVC Filter Fragments: When to Chase the Metal. Shared Ceiling: Both the Penn and Stanford series found that, at best,...
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The Golden Era of PE Trials: PRAGUE-26
This episode breaks down PRAGUE-26, a 558-patient NEJM randomized trial from 11 Czech centers testing whether low-dose thrombolysis through cheap generic infusion catheters beats anticoagulation alone, with expert commentary throughout from Dr. Jay Giri of Penn Medicine. The Protocol: Standard 4...
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The Heparin Paradox: When More is Less
This episode breaks down a 2026 JVIR letter to the editor describing intraprocedural heparin resistance during iliocaval thrombectomy in a 67-year-old man with stage IV diffuse large B-cell lymphoma and recurrent DVT. The Setup: A chest wall hematoma on therapeutic heparin forced cessation of...
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Fractured IVC Filter Fragments: When to Chase the Metal
This episode breaks down a 5-year Stanford registry of 82 patients presenting with fractured IVC filters and 185 embolized fragments, with commentary from both Dr. Andrew Kesselman, from Stanford Medicine, and Dr. Scott Trerotola, from Penn Medicine. The question is which fragments to chase and...
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Procedural Path to 91% Complete Pathologic Necrosis
This episode breaks down COBRAS, a 2026 Radiology multicenter study of 303 patients and 364 treatment-naive HCC tumors bridged to liver transplant with glass microsphere radiation segmentectomy. Listen to the end to hear an expert commentary by Dr. Sid Padia from UCLA Interventional Radiology.…
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Treat the Patient, Not the Picture: Rethinking Pelvic Venous Disease
This episode breaks down the latest Society of Interventional Radiology guidance on chronic pelvic pain of venous origin, focusing on patient selection and why technically successful procedures may not relieve pain. It concludes with expert commentary from Dr. Gloria Salazar of the UNC School of...
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The Inguinal Ligament Myth: What Really Drives Stent Failure
This episode pairs a 22-year Stanford retrospective of 1,094 lower extremity venous stents in 406 patients with the 3-year VIVO IDE trial of the Zilver Vena stent, and asks whether crossing the inguinal ligament actually dooms a venous stent. Where the Rule Came From: The recommendation against...
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The TIPS Trade-Off: Bleeding vs. Brain
This episode tackles the "Goldilocks dilemma" of TIPS: finding the stent diameter that stops a life-threatening variceal bleed without silently destroying a patient's cognition. Listen to the end to hear the expert commentary from Ziv Haskal from University of Virginia. Metabolic Cost: A TIPS...
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From CTA to the Angio Suite: A GI Bleeding Playbook
This episode breaks down the 2024 ACG/Society of Abdominal Radiology consensus statement alongside a 2025 Duke University update, mapping out exactly which imaging test to reach for at each stage of a GI bleed and when IR should step in. Dr. Rusty Hofmann from Stanford University closes with his...
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48 Hours to Failure: Anticoagulants and Portal Vein Stents
This episode breaks down a 2026 JVIR retrospective study from the Mayo Clinic (Bretzman et al.), examining portal vein stent outcomes in 182 pancreatic cancer patients, and why the usual fixes for early stent failure may be missing the real cause. At the end, Dr. Rusty Hofmann from Stanford...
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Wrist vs. Risk: Rethinking Transradial Access After MOSAIC
This episode unpacks a letters-to-the-editor debate sparked by the MOSAIC study (a Japanese multi-center trial in JVIR) and turns it into a practical framework for reducing embolic stroke risk during transradial visceral and hepatic interventions. Of 55 patients who underwent transradial access…
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Venous Stents: How Much Inflow is Enough?
This episode breaks down two recent retrospective studies in deep venous work: a stent that looks well deployed on the table can still thrombose within weeks, because the low-flow venous system punishes any stasis. Following, there is a great commentary by Dr. Rusty Hofmann from Stanford...
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14 Experts, One Consensus: How to Make Prostate Embolization Safer
This episode breaks down a 2026 Journal of Vascular and Interventional Radiology Delphi consensus in which 14 international experts standardized the technical steps of prostatic artery embolization (PAE) for benign prostatic hyperplasia (BPH). Across six procedural domains, the panel worked to…
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New PE Guidelines: When to Intervene
This episode breaks down the 2026 AHA/ACC/ACCP/ACPPE pulmonary embolism guidelines, highlighting the biggest changes to PE risk stratification, catheter-based interventions, and long-term follow-up. It also discusses how new randomized trials like STORM-PE and HI-PEITHO are shaping the future of...
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Embolization for Plantar Fasciitis: Technique and Early Results
This episode breaks down a 2026 Journal of Vascular and Interventional Radiology prospective case series evaluating transarterial embolization (TAE) as a minimally invasive treatment for chronic, refractory plantar heel pain. The study explores how targeting abnormal blood vessel growth may offer...
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Why PAE Made the American Urologic Association Guidelines
This episode breaks down a comprehensive 2024 Journal of Urology review on prostate artery embolization (PAE), exploring how it compares to transurethral resection of the prostate (TURP) and medical therapy for benign prostatic hyperplasia (BPH) and why it was added to the 2023 American Urologic...
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Can Thyroid Embolization Replace Surgery for Nodular Goiter?
This episode breaks down a JVIR retrospective study on Thyroid Artery Embolization (TAE), exploring whether embolization can serve as a non-surgical alternative for high-risk patients with massive retrosternal goiters who are poor candidates for thyroidectomy. Clinical Problem: Many patients with...
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Anti-platelets and venous stents: Lessons from ARIVA and C-TRACT
This episode breaks down the newly published ARIVA trial (Circulation), a randomized study testing whether adding aspirin to rivaroxaban after post-thrombotic iliofemoral venous stenting actually improves stent patency or simply adds bleeding risk. Clinical Question: For years, endovascular...
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C-TRACT Trial: Venous Stenting for Post-Thrombotic Syndrome
This episode breaks down the landmark C-TRACT trial (NEJM 2026), a phase 3 randomized study testing whether iliac vein stenting plus enhanced antithrombotic therapy actually improves outcomes in patients with moderate-to-severe post-thrombotic syndrome (PTS). The Clinical Question: Does restoring...
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Portosystemic Shunt Embolization
This episode breaks down a randomized controlled trial from Hepatology exploring whether prophylactic embolization of large spontaneous portosystemic shunts (SPSS) during TIPS can prevent post-procedural hepatic encephalopathy (HE). The Core Problem: Even successful TIPS can trigger HE by…
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The HI-PEITHO Trial: Intermediate Risk PE Unpacked
This episode breaks down the landmark HI-PEITHO trial (NEJM, March 2026), a multicenter randomized controlled trial of 544 patients that finally brings clarity to the category of intermediate-risk PE. The Inclusion Criteria: HI-PEITHO mandated a strict "intermediate-high" entry bar: RV:LV ratio >...
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SIR 2026 Abstract of the Year: Post-TIPS Liver Failure
This brief covers a massive 950-patient study identifying how to predict Post-TIPS Liver Failure (PTLF), which occurs in approximately 18% of cases. The 18% Problem: With nearly 1 in 5 patients failing after TIPS, this study provides a vital roadmap for identifying high-risk candidates before…
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SIR 2026 Abstract of the Year: Endovascular Denervation for Type 2 DM
This episode highlights the MILESTONE study, a ground-breaking first-in-human trial presented at the Society of Interventional Radiology (SIR) 2026 Annual Meeting. The research explores a novel endovascular approach to "rewiring" the body's metabolic control center to treat Type 2 Diabetes…
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The COLLISION Trial Explained
The COLLISION Explained This episode breaks down the practice-changing COLLISION Trial (Lancet Oncology, 2025) and explores how the IR community must scale its skills to meet the new standard of care. The Mic Drop: For decades, surgical resection was the undisputed gold standard for Colorectal...
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AHA/ACC 2026 Guidelines for the Evaluation and Management of Acute Pulmonary Embolism
AHA/ACC 2026 Guidelines for the Evaluation and Management of Acute Pulmonary Embolism The alphabet soup of societies (AHA/ACC/ACCP/ACP) has officially released the 2026 Multi-Society PE Guidelines. These guidelines move the field away from the blunt submassive labels and into a new era of…
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Stanford IR's Dr. Lynne Martin on PAVM Treatment
Stanford IR's Dr. Lynne Martin on PAVM Treatment This episode covers the critical paradigm shift in treating Pulmonary Arteriovenous Malformations (PAVMs) as detailed by Dr. Lynne Martin from Stanford Interventional Radiology. We discuss why the old "block the pipe" method is obsolete and how to...
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TIPS for TIPS: The "Best Chance" Protocol by Dr. John Louie (Stanford)
TIPS for TIPS: The "Best Chance" Protocol This episode tackles one of the most technically demanding procedures in IR, breaking down Dr. John Louie’s protocol to transform the traditional "blind stick" of a TIPS procedure into a visualized, scientific process. The Visualization Crisis: Standard...
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Thyroid Interventions: MWA vs RFA vs Embolization
Thyroid Interventions: RFA vs. Microwave & The Embolization Solution This episode breaks down the evolving landscape of benign thyroid management, pitting the two thermal ablation titans against each other and exploring the vascular solution for massive goiters. The 12-Month Divergence (RFA vs....
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Provocative Mesenteric Angiography from the Author, Dr. Charles Kim from Duke
Provocative Mesenteric Angiography: Safety and Efficacy in Occult GI Bleeding This episode tackles one of the most frustrating clinical challenges in Interventional Radiology: the patient with a recurrent occult GI bleed who has failed endoscopy and standard imaging. We analyze the largest...
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Night Call Tips from Dr. Rusty Hofmann
Dr. Rusty Hofmann, Professor of Interventional Radiology and founder of Wysdom, drops essential night-call wisdom after 25+ years of taking call: when & why to come in, how residents/fellows should present cases, and his famous 6 Cs mnemonic to never forget critical prep at 2–3 AM. Key takeaways:...
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Y-90 High Lung Shunt: The Mitigation Playbook
Y-90 High Lung Shunt: The Mitigation Playbook This episode is inspired by Professor of Interventional Radiology Dr. John Louie from Stanford IR and moves beyond the standard safety guidelines to provide a practical "playbook" for managing the high lung shunt patient, focusing on how to prevent...
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Portal Vein Embolization, Liver Venous Deprivation, and DRAGON Trial Data
Portal Vein Embolization, Liver Venous Deprivation, and the DRAGON Trial Data This episode synthesizes the latest CIRSE standards and DRAGON trial findings to guide Interventional Radiologists in maximizing the Future Liver Remnant (FLR) and minimizing Post-Hepatectomy Liver Failure (PHLF). The...
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Genicular Artery Embolization (GAE) with First-in-Human Resorbable Microspheres
GAE for Knee Osteoarthritis: The Resorbable Solution This episode explores the first-in-human trial of Sakura, a novel resorbable alginate microsphere designed specifically to solve the safety trade-offs of Genicular Artery Embolization (GAE) for knee osteoarthritis. The Problem with Current...
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5 Keys to Thriving in IR Residency with Dr. Kim Scherer (Cornell IR/DR Associate Program Director)
In this episode, Dr. Kim Scherer, Assistant Professor of Radiology at Weill Cornell and Associate Program Director, shares her top five pieces of advice for navigating the challenges of an Interventional Radiology residency. You Get Out What You Put In: Residency isn't medical school; there are…
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Y-90 Liver Toxicity: Understanding and Preventing REILD
Y-90 Liver Toxicity: Understanding and Preventing REILD This episode investigates the specific, aggressive liver injury that can follow Y-90 Radioembolization—Radioembolization-Induced Liver Disease (REILD)—defining it not as simple radiation necrosis, but as Hepatic Sinusoidal Obstruction…
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Acute Portal Venous Thrombosis in Non-Cirrhotic Patients: When Anticoagulation Isn't Enough
This episode provides a deep dive into the management of Acute Porto-Mesenteric Venous Thrombosis (PVT) in non-cirrhotic patients, a condition with a 30-day mortality rate of up to 32% if the clot extends into the mesenteric veins. The Limitations of Meds: We discuss why systemic anticoagulation...
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Provocative Mesenteric Angiography: Safety and Efficacy in Occult GI Bleeding
Provocative Mesenteric Angiography: Safety and Efficacy in Occult GI Bleeding This episode tackles one of the most frustrating clinical challenges in Interventional Radiology: the patient with a recurrent occult GI bleed who has failed endoscopy and standard imaging. We analyze the largest...
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Evidence for Intravascular Ultrasound (IVUS) in PAD
Evidence for IVUS in PAD This episode uncovers the compelling evidence behind Intravascular Ultrasound (IVUS), a technology that is revolutionizing the treatment of Peripheral Artery Disease (PAD) by fixing the fundamental flaw of traditional angiography: its "2D shadow" limitation. The Problem...
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The Must Knows of IR: Part 3 (For first timers in IR)
IR Procedural Skills: Pigtail Catheters and Manual Hemostasis This episode breaks down the mechanics of two foundational interventional skills—drainage catheter deployment and arterial compression—where proper technique is the only line of defense against complications. The Pigtail Mechanism: We...
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The Must Knows of IR: Part 1 (For first timers in IR)
IR Basics: Needles, Wires, Catheters, and Sheaths This episode provides a rapid-fire masterclass on the four foundational tools of Interventional Radiology and how to navigate the complex sizing systems that dictate their use. The Sizing Headache: We demystify the three conflicting measurement...
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The Must Knows of IR: Part 2 (For first timers in IR)
IR Procedural Best Practices: Setup, Grip, and Wire Handling This episode moves beyond basic instrument knowledge to focus on the subtle physical habits and organizational tricks that distinguish expert operators from novices, aiming to maximize efficiency and safety. Air Bubble Management: We...
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Intro to Embolics
This fundamental episode builds your mental toolbox by outlining the three main categories of embolic agents you'll use every single day. We break down the core principles, "why," and critical safety rules for: Particulates (The "Downstream" Stuff): Learn the difference between temporary…
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MSK Embo - Possible Applications
What if chronic joint pain from osteoarthritis and tendinopathy isn't just "wear and tear"? This episode explores the cutting-edge, minimally invasive world of Musculoskeletal Embolization. Discover the science behind how this procedure targets abnormal blood vessels (angiogenesis) and nerves…
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IVC Filters
This episode is a complete introduction to IVC filters, designed for the IR trainee. We cover all the essentials you need to know from the initial consult to long-term follow-up. What you'll learn: The "Why": Why filters are not first-line therapy and are only used to prevent PE. The "When": The...
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Portal Hypertension, TIPS, and RTO—Latest AASLD Guidance
🎙️ Wysdom Radio: Portal Hypertension, TIPS, and RTO—Latest AASLD Guidance This episode breaks down the critical differences between the two main endovascular strategies for managing variceal bleeding in patients with portal hypertension: TIPS (Transjugular Intrahepatic Portosystemic Shunt): A...
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Bronchial Artery Embolization (BAE)
🎙️ Wysdom Radio: BAE Insights from the Experts This episode of Morning Rounds delivers a direct line to critical research on Bronchial Artery Embolization (BAE), the life-saving procedure used to stop massive hemoptysis (coughing up blood). CF Patient Effectiveness: We analyze a long-term…
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ABOUT THIS SHOW
We deliver short, focused episodes on the main concepts and procedures you actually need to know. It’s the perfect clinical companion for your drive to work or your daily workout. Come learn IR on the go!Check us out at https://www.medicalwysdom.ai/
HOSTED BY
Wysdom
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