All Episodes
Cardiology Trials — 144 episodes
Summary and discussion of SAFE-T and RACE II
Summary and discussion of AFFIRM and RACE
Special episode (ACC 2026: CHAMPION-AF, HI-PEITHO)
Summary and discussion of VICTORIA and VICTOR
Summary and discussion of DAPA-HF and EMPEROR-Reduced
Special episode (AHA 2025: OCEAN, ADAPT AF-DES)
Special episode (AHA 2025: VESALIUS-CV, DECAF)
Summary and discussion of PARADIGM-HF and PIONEER-HF
Special episode (ESC 2025: AQUATIC, VICTOR)
Special episode (ESC 2025: REBOOT-CNIC, BETAMI-DANBLOCK, DIGIT-HF)
Summary and discussion of BEST and SENIORS
Review of the A-HeFT trial
Review of the CHARM-Alternative trial
Summary and discussion of Carvedilol Prospective Randomized Cumulative Survival Study, Val-HeFT, CHARM-Added and CIBIS-II
Review of the CIBIS-II Trial
Review of the CHARM-Added trial
Review of the Val-HeFT trial
Review of the Carvedilol Prospective Randomized Cumulative Survival Study
Summary and discussion of U.S. Carvedilol Heart Failure, DIG, RALES, MERIT-HF, and ATLAS
Review of the ATLAS trial
Review of the MERIT-HF trial
Review of the RALES trial
Review of the DIG trial
Review of the U.S. Carvedilol Heart Failure Study
Summary and discussion of V-HEFT II and SOLVD
Review of the SOLVD trials
Review of the V-HEFT II trial
Summary and discussion of V-HEFT I and CONSENSUS
Review of the CONSENSUS trial
Review of the V-HEFT I Trial
Review of the CULPRIT-SHOCK Trial
Summary and discussion of MOSCA-FRAIL and SENIOR-RITA
Review of the SENIOR-RITA trial
Review of the MOSCA-FRAIL trial
Summary and discussion of TACTICS-TIMI 18, RITA 3 and ICTUS
Review of the ICTUS trial
Review of the RITA 3 trial
Review of the TACTICS-TIMI 18 trial
Summary and discussion of PRAMI, COMPLETE and FULL REVASC
Review of the FULL REVASC trial
Review of the COMPLETE trial
Review of the PRAMI Trial
Summary and discussion of TAPAS and TASTE
Summary and discussion of trials of fibrinolysis vs invasive strategy in STEMI
Review of the TASTE trial
Summary and discussion of OAT
Review of the TAPAS trial
Review of the STREAM trial
Summary and discussion of FAME and RIVAL
Review of the OAT Trial
Review of the DANAMI-2 trial
Review of the Primary Angioplasty in Myocardial Infarction Study Group trial
Review of the RIVAL trial
Review of the FAME trial
Summary and discussion of NORSTENT
Review of the NORSTENT trial
Our discussion of "Revisiting the PLATO trial"
Revisiting the PLATO trial
Summary and discussion of RAVEL, TAXUS-IV and SPIRIT IV
Review of the SPIRIT IV Trial
Review of the TAXUS-IV trial
Review of the RAVEL trial
Summary and discussion of FAME 3, BARI 2D and PREVENT
Review of the PREVENT trial
Summary and discussion of trials of PCI vs CABG
Review of the BARI 2D trial
Review of the FAME 3 trial
Review of the EXCEL trial
Review of the NOBLE Trial
Review of the FREEDOM trial
Review of the SYNTAX trial
Review of the ORBITA-2 trial
Summary and discussion of ISCHEMIA, ISCHEMIA-CKD, ORBITA and REVIVED-BCIS2
Review of the REVIVED-BCIS2 trial
Review of the ORBITA trial
Review of the ISCHEMIA and ISCHEMIA-CKD trials
Summary and discussion of RITA-2, atorvastatin vs angioplasty, COURAGE and FAME 2
Review of the FAME 2 Trial
Review of the COURAGE Trial
Review of the Atorvastatin versus Revascularization Treatment Investigators Trial
Review of the RITA-2 trial
Summary and discussion of STICH and ACME
Review of the ACME trial
Review of the STICH trial
Summary and discussion of trials of coronary artery bypass surgery in stable angina
Review of the Coronary Artery Bypass Graft Surgery Trialists Collaboration
Review of the Coronary Artery Surgery Study (CASS)
Review of the European Coronary Surgery Study
Review of the Veterans Administration Cooperative Study
A review of medical management after acute coronary syndrome
Summary and discussion of REDUCE-AMI
Review of the REDUCE-AMI trial
Summary and discussion of PARADISE-MI and EMPACT-MI
Review of the EMPACT-MI Trial
Review of the PARADISE-MI Trial
Summary and discussion of IMPROVE-IT, CANTOS, CIRT and COLCOT
Review of the COLCOT trial
Review of the CIRT trial
Review of the CANTOS Trial
Review of the IMPROVE-IT trial
Summary and discussion of ACCOAST and ISAR-REACT 5
Review of the ISAR-REACT 5 Trial
Review of the ACCOAST trial
Summary and discussion of TACT and ATLANTIC
Review of the ATLANTIC trial
Summary and discussion of NICE-SUGAR, TRITON-TIMI 38, TRILOGY ACS, PLATO and ATLAS ACS 2-TIMI 51
Review of the TACT Trial
Review of the ATLAS ACS 2-TIMI 51 trial
Review of the CURRENT-OASIS 7 trial
Review of the TRILOGY ACS trial
Review of the PLATO Trial
Review of the TRITON-TIMI 38 Trial
Review of the HORIZONS-AMI trial
Review of the OASIS-6 trial
Review of the OASIS-5 trial
Summary and discussion of CURE and DIGAMI 2
Review of DIGAMI 2
Review of the CURE Trial
Summary and discussion of MIRACL and PROVE IT-TIMI 22
Review of the PROVE IT-TIMI 22 Trial
Review of the MIRACL Trial
Summary and discussion of DIGAMI and FRISC
Review of the FRISC trial
Review of the DIGAMI trial
Summary and discussion of TRACE and EPHESUS
Review of the EPHESUS Trial
Review of the TRACE Study
Summary and discussion of CAPRICORN and COMMIT
Review of the COMMIT Trial
Review of the CAPRICORN Trial
Summary and discussion of SAVE and AIRE
Review of Acute Infarction Ramipril Efficacy (AIRE) Trial
Review of Survival and Ventricular Enlargement (SAVE) Trial
Summary and discussion of GISSI-3 and ISIS-4
Review of the ISIS-4 Trial
Review of the GISSI-3 Trial
Summary and discussion of CAST and ISIS-3
Review of the ISIS-3 Trial
Review of the Cardiac Arrhythmia Suppression Trial (CAST)
Summary and discussion of GISSI-1, 2 and ISIS-2
Review of the GISSI-2 Trial
Review of the ISIS-2 Trial
Review of the GISSI-1 Trial
BHAT and ISIS-I trials