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1

ICYMI: Chronic Hepatitis B: Treatment Criteria Expansion and Demystifying the “Grey Zone”

2

Appendectomy as an Adjunct in Refractory Ulcerative Colitis

3

From Confusion to Clarity: A Practical Guide to Hepatic Encephalopathy

4

What to expect when expecting with IBD

5

Surgery in cirrhosis: Strategies for risk stratification and optimization

6

Can tacrolimus tame esophageal lichen planus?

7

IBD surveillance colonoscopy: to spray or not to spray!

8

Increased ATTENTION to Early Initiation of Antiviral Therapies in Chronic Hepatitis B Based on Viral Load

9

Optimizing Bowel Preparation for Colonoscopy: Insights from the USMSTF Recommendations

10

Tulisokibart, a New Drug for Moderate-to-Severe UC That May Come With Personalized Medicine

11

Tofacitinib in Acute Severe Ulcerative Colitis (TACOS): A Randomized Controlled Trial

12

Hot Take: Can We Lengthen Surveillance Intervals After EMR With Margin Thermal Ablation?

13

Redefining Risks in CDH1 Hereditary Diffuse Gastric Cancer

14

The Edge of a New Frontier: Anti-TL1A Monoclonal Antibodies for Ulcerative Colitis

15

Cold vs Hot Snare Resection of Large Polyps: A Cooler, Safer Approach for Large Colorectal Polyps

16

Combination Therapy as Primary Prophylaxis for High-Risk Esophageal Varices

17

Long Term Efficacy and Safety of Dupilumab for Eosinophilic Esophagitis

18

Subcutaneous Infliximab for Maintenance of IBD Remission: Added Convenience with Potential for Improved Efficacy?

19

On-Demand Vonoprazan for Non-Erosive Reflux Disease Symptoms: A New Option

20

Suboptimal Adherence to Guidelines When Recommending Timing of Repeat Colonoscopy

21

Reintroducing Foods After Completing Restrictive Low FODMAP Diet

22

Quality Indicators for Colonoscopy: New Targets… But Will They Be Measured?

23

Decreasing Cirrhosis Risk in MASLD: Don’t Drink Alcohol!

24

A PPI a Day Keeps the GI Bleed Away in the ICU

25

A Laser Ruler to Hit the Mark on Polyp Size

26

ACG Guideline on Treatment of Helicobacter pylori: New Recommendations… Will Practice Change?

27

Risankizumab is Superior to Placebo for Induction and Maintenance of Moderate-Severe Ulcerative Colitis (UC): Assessing the UC Treatment Paradigm

28

Standardized Training for Endoscopic Mucosal Resection of Large Polyps: Does it Reduce Recurrence?

29

Diagnostic Yield of Prolonged Wireless pH vs 24-hour pH-Impedance Monitoring for Evaluation of Chronic Laryngeal Symptoms

30

Risankizumab is Superior to Ustekinumab for Induction and Maintenance of Crohn’s disease: The SEQUENCE Trial

31

Vonoprazan is Efficacious for Non-Erosive Reflux Disease (NERD): An Alternative for PPI-Resistant NERD Patients?

32

ERCP with Extracorporeal Shock-Wave Lithotripsy for Chronic Pancreatitis: Is It A “Sham” for Improving Pain?

33

ICYMI: ACG Clinical Guideline on Gastroparesis-Limited Evidence-Based Options

34

Tirzepatide Produces NASH Resolution and Decreases Fibrosis: Results from the SYNERGY-NASH Trial

35

Oral Vonoprazan for Prevention of High-Risk Peptic Ulcer Rebleeding: A Better Alternative than IV PPIs?

36

Long-Term Efficacy and Safety of Ustekinumab for Ulcerative Colitis: 4-Year Data from the UNIFI Maintenance Study

37

Do Not Extend Interval Between CRC Screening Colonoscopies from 10 to 15 Years: Perils of Administrative Databases

38

Stemming the Tide: Is Long-acting, IM Octreotide Injection Better than Standard of Care for Angiodysplasia-related GI Bleeding?

39

Multi-Target Stool RNA Test for Colorectal Cancer Screening: When Should You Use It?

40

Can IV Metoclopramide Improve Endoscopic Visualization for Patients with Active Upper Gastrointestinal Bleeding?

41

When to Discontinue Colon Polyp Surveillance in Older Adults?

42

Budesonide Oral Suspension Improves Outcomes in Eosinophilic Esophagitis

43

Multi-Target Stool DNA Test for CRC Screening: How Accurate is the New Version?

44

Linaclotide Effective for Functional Constipation in 6-17 Year Olds: First FDA-Approved Constipation Treatment for Children

45

PROFILE: Can Molecular Biomarkers Predict Outcomes to Crohn’s Disease Treatment?

46

Cell-free DNA Blood Test for CRC Screening: A Promising Development but Won’t “Eclipse” Current Tools

47

Resmetirom Produces NASH Resolution and Decreases Fibrosis: Results from the MAESTRO-NASH Trial

48

How Effective Are Obesity Medications for Reducing Hepatic Decompensation in NASH?

49

Ustekinumab and Vedolizumab Demonstrate Safety During Pregnancy: Updates from the PIANO Registry

50

ESD vs EMR for Large Non-Pedunculated Colon Polyps: Fewer Recurrences but More Complications

51

ICYMI: Eating “Healthy” to Minimize Colon Cancer

52

When to Discontinue Colorectal Cancer Screening in Older Adults: Chronological Age or Life Expectancy?

53

ICYMI: How Frequently Should We Perform Colonoscopy in Patients with Serrated Polyposis Syndrome?

54

Add Prophylactic Pancreatic Duct Stents to Rectal Indomethacin to Minimize Post-ERCP Pancreatitis in High-Risk Patients

55

Non-Erosive GERD Does Not Lead to an Increased Risk of Esophageal Adenocarcinoma

56

Making Bowel Preparation Palatable: Efficacy of a Novel Sports Drink Flavor-Optimized PEG and Sulfate Bowel Preparation

57

Continued Treatment With Tirzepatide Is Necessary to Maintain Weight Loss

58

Mirikizumab Is Effective for Induction and Maintenance of Ulcerative Colitis

59

Is Early Ileocecal Resection for Crohn’s Disease An Appropriate Primary Treatment?

60

Which Endoscopists Benefit from Using Computer-Aided Detection of Polyps During Colonoscopy?

61

Post-Colonoscopy Colorectal Cancer Due to Missed Polyps in Proximal Colon or Rectum with Sub-Optimal Bowel Cleansing

62

Overt Evidence for the Efficacy and Safety of Thalidomide in Gastrointestinal Bleeding from Small Intestinal Angiodysplasia

63

Low-dose Tricyclic Antidepressants for Irritable Bowel Syndrome: Definitive Evidence of Benefit from ATLANTIS

64

Hepatocellular Carcinoma Incidence Rates Are 2%-3% in US Patients with Cirrhosis Regardless of Etiology

65

ICYMI: Lynch Syndrome-An Aspirin a Day Keeps Colorectal Cancer Away!

66

Etrasimod, a Sphingosine 1-Phosphate Receptor Modulator, for Moderate-Severe Ulcerative Colitis: New Options for Oral Therapy

67

Post-Endoscopy Esophageal Adenocarcinoma: Take a PEEC at Endoscopy Quality in Barrett's Esophagus

68

Surveillance of Branch Duct IPMN – Enough is Enough, At Least in Older Adults and Small, Stable Lesions

69

GI Adverse Events with GLP-1 Agonists for Weight Loss: Understanding the Risks

70

The New Frontier of Combination Therapy for IBD: The VEGA RCT

71

ICYMI: Biosimilar BI 695501 Has Similar Safety and Efficacy to Adalimumab for the Treatment of Crohn’s Disease: VOLTAIRE-CD Study

72

Hepatitis C Virus Testing and Treatment - A Call To Action

73

PPIs are NOT Associated with Dementia: Refuting Sensational Claims in a Post-Modern Epidemiologic Era

74

Time To Simplify ADR Calculation for Colonoscopy Quality Reporting

75

Cannabidiol: A Potential Therapeutic Option for Idiopathic and Diabetic Gastroparesis

76

American College of Physicians Guidance Statement on Colorectal Cancer Screening: Pitfalls of Second-Guessing Guidelines

77

Long Road to Achieving Competence in Cold Snare Polypectomy: Video-Based Feedback Can Help!

78

“Cooking Up Something New” with a One-Food Elimination Diet: A Simpler Approach to Dietary Therapy for Eosinophilic Esophagitis

79

Kiwifruit-A Specific Food To Improve Stool Frequency in Patients with Mild Constipation

80

ICYMI: Albumin Infusions Do Not Improve Outcomes in Hospitalized Patients with Decompensated Cirrhosis-The ATTIRE Trial

81

Surveillance Colonoscopy Recommendations in Older Adults With Limited Life Expectancy– More Work to be Done!

82

Upadacitinib Is Effective for the Induction and Maintenance of Moderate-to-Severe Crohn’s Disease

83

Vedolizumab: An EARNEST Option for the Management of Chronic Pouchitis

84

Bariatric Surgery Is Superior to Lifestyle Changes + Best Medical Care for Metabolic Dysfunction-Associated Steatohepatitis: The BRAVES Study

85

Colonoscopy for Colon Polyp Surveillance: Avoid Recommending Early Surveillance

86

Free Online Program Improves Adenoma Detection Rate and Decreases Post-Colonoscopy Colorectal Cancer

87

Screening Colonoscopy in the Elderly Population-Is Less Better?

88

Cephalosporins and Ciprofloxacin Still Appropriate First-Line Treatment for Spontaneous Bacterial Peritonitis

89

AGA-ACG Clinical Practice Guideline on Chronic Idiopathic Constipation Treatments: Parsing Benefits and Risks

90

Disposable Elevator Caps for Duodenoscopes Decrease Persistent Bacterial Contamination Without Hindering Technical ERCP Performance: The ICECAP Trial

91

Over-the-Scope Clips Decrease Non-Variceal Upper GI Bleeding vs Standard Endoscopic Treatment… In the Right Patient

92

Prophylactic Antibiotics Do Not Improve Mortality in Severe Alcoholic Hepatitis Treated with Corticosteroids

93

SEAVUE: a Sea of Change in Biologic Positioning for Crohn’s Disease

94

ICYMI: Vedolizumab Is Superior to Adalimumab for Clinical Remission and Endoscopic Improvement of Ulcerative Colitis-The VARSITY RCT

95

Vibrating Capsules for Chronic Constipation: The New Non-Pharmacologic Approach

96

ICYMI: Can we prevent hepatic decompensation? Most likely, with nonselective beta blockers.

97

Tumor-based screening for Lynch Syndrome: Check Every Colorectal Cancer

98

What are the Causes of Post-colonoscopy Colorectal Cancer?

99

10-Year Intervals After Normal Screening Colonoscopy: It’s Not Too Long with High-Quality Colonoscopy

100

Cold Snare Decreases Post-Polypectomy Bleeding vs Hot Snare for Small Polyps

101

Dupilumab, an IgG4 Monoclonal Antibody, for Eosinophilic Esophagitis: Revising the Treatment Paradigm

102

Endoscopic Sleeve Gastroplasty Is Effective for Patients with Obesity Who MERIT Intervention

103

Early Colonoscopy for Acute Lower GI Bleeding Usually Is Not the Answer

104

Direct-Acting Antiviral Therapy for Hepatitis C Virus Decreases All-Cause Mortality and Decompensated Cirrhosis: Treat (Virtually) Everyone

105

ICYMI: Is Terlipressin for the Treatment of Hepato-Renal Syndrome Ready for Primetime: Results of the CONFIRM Trial

106

Risankizumab, an Interleukin-23 Inhibitor, for Moderate-Severe Crohn’s Disease: Advancing Care Beyond Anti-TNF Therapy

107

Risankizumab, an Interleukin-23 Inhibitor, for Moderate-Severe Crohn’s Disease: Advancing Care Beyond Anti-TNF Therapy

108

When It’s Not Acid Reflux: Managing PPI-Resistant GERD Patients Based on Bravo Results

109

RBX2660, a Donor Stool Product for Fecal Microbiota Transplant, Decreases Recurrent Clostridioides difficile Infection: The First FDA-Approved Live Biotherapeutic Product

110

NSAID Use and the Risk of IBD Exacerbations: Fact or Fiction

111

Continuing Anti-TNF Agents past 24 Weeks of Pregnancy Associated with Fewer IBD Relapses with No Increase in Adverse Fetal Outcomes

112

Ozanimod, a Selective Selective Sphingosine-1-Phosphatase Receptor Modulator, for Moderate-Severe Ulcerative Colitis: Re-Thinking the Top-Down Treatment Algorithm for UC

113

ICYMI: Surgery is Superior to Medical Therapy for PPI-Refractory Heartburn in the “Right” Patients

114

Vonoprazan, a Potassium-Channel Acid Blocker, is Superior to Lansoprazole for Managing Erosive Esophagitis

115

Reinvestigating the Lack of Association Between Proton Pump Inhibitor Use and Mortality by Accounting for Reverse Causation

116

Upadacitinib, a Selective JAK1 Inhibitor, for Moderate-Severe Ulcerative Colitis: Adjusting the Top-Down Treatment Algorithm for UC

117

Colonoscopy Reduces CRC Incidence and CRC-Related Mortality…. If You Get It!

118

High Adenoma Detection Rate Decreases Post-Colonoscopy CRC in FIT-Based Screening Program: Quality Matters!

119

Acute pancreatitis: Need IV fluid resuscitation but avoid a WATERFALL!

120

ICYMI-Pantoprazole Prophylaxis Does Not Reduce 90-day Mortality and Clinically Significant Adverse Events in ICU Patients

121

Achieve IBD Remission Before Pregnancy: PIANO Registry Data Shows Adverse Perinatal Outcomes For Infants Associated with IBD Flares and Steroid Use; and Continue Thiopurines and Anti-TNF Agents If Your IBD Patient Becomes Pregnant

122

Time to Increase Adenoma Detection Rate Benchmarks for Screening Colonoscopies

123

ADR Isn’t the Only Game in Town: Proximal Serrated Lesion Detection Rates Predicts Interval Cancer Risk

124

Tiny Polyps-It’s OK to Remove Polyps equal or less than 3mm with Large Biopsy Forceps

125

Prophylactic Rifaximin Decreases Post-TIPS Hepatic Encephalopathy

126

SER-109, an Oral Microbiome Therapy, Decreases Recurrent Clostridiodes difficile Infection

127

When Is Routine Prophylactic Clipping Indicated Post-Polypectomy?

128

Tenapanor (IBSRELA) for Treatment of IBS-C: Effective over 26 Weeks

129

Low Grade Dysplasia in Barrett’s Esophagus – Get Two Expert GI Pathologist Reviews and Repeat EGD After PPI Treatment

130

Therapeutic Drug Monitoring of Maintenance Infliximab Is Beneficial for Patients with Immunemediated Inflammatory Diseases

131

Endoscopic Eradication Therapy for Neoplastic Barrett’s Esophagus Demonstrates 94% Treatment Success and Long-term Durability

132

Increased Risk of Metachronous Neoplasia After Incomplete Polyp Resection – Time to CARE About Polypectomy Technique!

133

It’s a Bad “Prep” Even Though the Patient Took It Correctly: Consider 15 mg Bisacodyl plus 4-Liter PEG Split Prep Before Next Colonoscopy

134

Effectiveness of Intermittent Fasting for Weight Loss: It’s Not Just When You Eat, but What You Eat, Too!

135

Family Matters: Increased Risk of Colorectal Cancer among Individuals with Family History of Polyps

136

Slow Down to Speed Up Quality: Longer Withdrawal Time of 9 Versus 6 Minutes Increases Adenoma Detection Rate

137

Drainage for Infected Pancreatic Necrosis – Earlier Is Not Better

138

Hereditary Syndrome Risk Assessment in all Colorectal Cancer Patients: Keep it Simple!

139

Treating All the Symptoms of IBS-C: Linaclotide Significantly Decreases Abdominal Pain, Bloating, and Discomfort

140

A New “Pill Prep” for Colonoscopy: An Effective Alternative for Individuals Who Won’t Drink GoLytely®

141

Inching Closer to a NASH Cure: Daily Semaglutide Achieves Resolution of NASH but Not Fibrosis after 72 Weeks

142

Computer-aided Detection Systems increase detection of non-advanced adenomas, but is it ready for prime-time?

143

Piecemeal Cold Snare Polypectomy of Large SSP: Cold Is the New Hot

144

Once-Weekly Semaglutide in Adults with Overweight or Obesity

145

Screening Colonoscopy Decreases Colorectal Cancer Incidence and Related Mortality in Healthy Patients Over 75

146

Acute Myeloid Leukemia and Myelodysplastic Syndrome with IBD and Thiopurines Impact on Risk