All Episodes - StemCells@Lunch Digested
Keeping the public up to date with current research taking place in the stem cell research community. Listen to guest speakers discuss their work, how they got to where they are today and their hopes for the future of stem cell research. Hosted by King's College London Centre for Stem Cells & Regenerative Medicine.
View Podcast Details156 Episodes
Episode 153: Dr Ina Sonnen "It is possible to have a career and a family in science"
In this episode, Ina Sonnen, a researcher at the Hubrecht Institute in the Netherlands, is interviewed by Postdocoral researcher JF Darrigrand. Ina explains which are the big questions studied in her lab, notably how cells can communicate not only via the nature of signals they exchange but also through the dynamics of these signlas. She shares how advances in microscopy, microfluidics and cell culture are helping researchers to make more and more discoveries. Having recently founded her lab, she tells us more about what she found was either challenging or rewarding in her new role. Lastly, she insists on why she thinks being a scientist is a good job when you want to start a family. To find out more about Ina's research, check out the following links: https://www.sonnenlab.org
Episode 152: Prof Andrew Ewald "Understand the simple rules generating apparent complexity"
In today’s episode, Prof. Andrew Ewald, Director of the Cell Biology Department at the Johns Hopkins School of Medicine is interviewed by Inês Tomás. Prof Ewald explains how he transitionned from a background in physics to the field of cancer biology. He touches upon why cancer is such a specific type of disease, how cancer cells talk to each other during metastasis, and how their interaction with immune cells is crucial for disease development. Prof Ewald also discusses the evolution of the tools available for cancer biologists and how the emergence of new technologies are changing the field. Lastly, he shares some inspiring mentoring advice on how to reach an interdisciplinary and rewarding career.
Episode 151: Dr William Roman "Use your PhD as a platform"
In today’s episode, Dr. William Roman, a research associate at Stanford University, is interviewed by Dr. Davide Danovi. William explains how he is combining live cell imaging and quantitative approaches to answer fundamental questions in muscle biology. He shares some inspiring mentoring advice on how to let students use their PhDs as platforms to express themselves throught their science and discover what type of science they like, both in terms of subject and technique.
Episode 150: Prof Shalev Itzkovitz "We can infer the design principles of organs"
In today’s episode, Shalev Itzkovitz, a professor at the Weizman Institute, Israel, is interviewed by Postdocoral researcher Georgina Goss. Shalev shares the discoveries of his lab on the design principles that shape and maintain metabolic organs such as the intestine and the liver. He explains the very advanced techniques used in modern biology, and more specifically in his lab, to address such fundamental questions. Having started his education in mechanical engineering, he discusses what motivated him to transition to the resolution of biological questions and how resolving these questions is somewhat similar to retro-engineering. Lastly, he touches upon what fascinates him in studying the biology of metabolic organs. To find out more about Shalev's research, check out the following links: https://shalevlab.weizmann.ac.il
Episode 149: Professor Xin Chen-“We are very fascinated by this kind of ‘immortality’ of germ cells”
In today’s episode, Prof Xin Chen, a group leader at Johns Hopkins University in Baltimore, is interviewed by PhD student Daria Belokhvostova. Xin takes us into the world of germline stem cell epigenetics and how its regulation can influence the ability of these cells to divide asymmetrically. She shares her passion for the biology of germ cells and explains why the fruit fly Drosophila is such a good system for her studies. Xin talks about how scientific collaborations are helping to expand her findings to different biological systems. Finally, she tells us about the challenges of keeping the lab running through pandemic times and the joy of seeing in-person interactions come back. To find out more about Xin’s research, check out the following link: https://bio.jhu.edu/directory/xin-chen/
Episode 148: Dr Allison Bardin- “Unexpected results lead to novel discoveries”
In today’s episode, Dr Allison Bardin, a group leader at Institut Curie, is interviewed by PhD student Vassia Salameti. Allison talks about how she got interested in asymmetric cell division while working on budding yeast, followed by her work on fly as a postdoc that derived her into the field to study cell fate acquisitions and stem cell biology. She shared the details about how Drosophila is excellent model to study various genetic alterations and cost effective. Allison further emphasised on the importance of fundamental research and how that could lead to interesting discoveries that could be further translated into clinics. Finally, she talks about importance of collaboration as well as importing expertise in lab along with some interesting advice for PhDs who plan to pursue academic career. To find out more about Allison's research, check out the following link: https://science.institut-curie.org/research/biology-cancer-genetics-and-epigenetics/developmental-biology-and-genetics/team-bardin/
Episode 147: Professor Yukiko Yamashita- “Junk DNA may not be all Junk”
In today’s episode, Prof Yukiko Yamashita, a group leader at Whitehead Institute for Biomedical Research, MIT, is interviewed by PhD student Joshua Reeves. Yukiko talks about how her lab got interested in understanding the possible mechanism of non siter chromatid segregation in germline cells. She talks about how they started looking at the interesting mechanisms regulating the immortality of germlines cells in Drosophila. Yukiko also shares her opinion regarding Junk DNA and how it might not all be junk like noncoding RNAs. Lastly, she shares her advice to be learner for rest of life and get used to stepping outside comfort zone. And to become comfortable not being expert all the time. To find out more about Yukiko’s research, check out the following link: https://yamashitalab.wi.mit.edu/
Episode 146: Prof Ludo Van Den Bosch– “Exciting time for researchers”
In today’s episode, Prof Ludo Van Den Bosch a group leader at VIB-KU Leuven Center for Brain & Disease Research, is interviewed by PhD student Abigail Isaacson. Ludo talks about his labs goal and how they use different model systems to understand disease as good as possible with goal to develop therapies. He also highlighted the importance of using different models from fruit fly, zebrafish to mice depending on context and questions. Ludo also emphasized about obstacles in managing ALS along with advancement in past 25yrs and how iPSCs have made big difference and given new insights for understanding diseases. Ludo shared his experience as being a scientist and how much he enjoy interaction with young people and other fellow colleagues. To find out more about Ludo's research, check out the following link: https://cbd.vib.be/labs/van-den-bosch-lab
Episode 145: Prof Elena Ezhkova- “The more you try understand science the more interesting it gets”
In today’s episode, Prof Elena Ezhkova, a group leader at Icahn School of Medicine, is interviewed by PhD student Vassia Salameti. Elena talks about the potential of stem cells in therapy and how her interest developed towards understanding the role of epigenetic regulators in stem cell reprogramming. She shares about how companies are getting interested in small molecular drugs that target epigenetic regulators which could be used as personalized therapy. Elena also emphasizes the importance of clinical collaboration and highlights how important it is to get the inputs from clinicians at the beginning of project to get better understanding of the disease. Lastly, she shares her advice for PhDs to find the research direction of interest and not be afraid things will work out!!! To find out more about Elena's research, check out the following link: https://www.ezhkova-lab.com/
Episode 144- Prof Filipe Pereira- "It's about defining what will keep you fueled for years"
In today’s episode, Prof Filipe Pereira, a professor at Lund University, Sweden, is interviewed by postdocoral researcher Jean-Francois Darrigrand. Filipe shares how he started his career in the fields of stem cells reprogramming and immunotherapy, as well as his experience working in the US and different european countries. Filipe also discusses about how he balances his activities of leader of an academic group and of a biotech company. Lastly, he explains why mentoring is a fantastic source of motivation for him. To find out more about Filipe's research, check out the following link: https://pereiralab.com/team/carlos-filipe-pereira/
Episode 143 -Prof Denis Duboule - "As long as people are happy in your lab, it's fine"
In today’s episode, Prof Denis Duboule, a professor of developmental biology at EPFL and Univeristy of Geneva is interviewed by PhD student Abigail Isaacson. Denis talks about how his first interest for mushrooms initiated his whole career in biology. He shares with us his fascination for the encoding of time in the genome, which ensures the proper development of embryos. Denis also talks about how priotities change during the life of a laboratory head, shifting from publishing to seeing your lab members grow and succeed on their own. To find out more about Denis' research, check out the following link: https://genev.unige.ch/research/laboratory/Denis-Duboule
Episode 142 -Prof Dagmar Iber- "Don't play too safe and be lucky."
In today’s episode, Prof Dagmar Iber, a professor at ETH, Zurich, is interviewed by PhD student Vasiliki Salameti. Dagmar talks about the similarity between investment banking and academia . She describes her interest in modelling organogenesis and patterning systems. She discusses the importance of collaboration. She also advised students to take risk and initiative to try to do things they want to. As a university professor, she shared how she enjoyed the scientific journey in finding things out, but also teaching and seeing students grow. To find out more about Dagmar's research, check out the following links: https://www.bsse.ethz.ch/cobi https://bsse.ethz.ch/cobi/group/people/person-detail.MTQ5NDI0.TGlzdC8yMjA0LC0xMDM3ODQxNDk3.html
Episode 141 - Dr Vikas Trivedi - “You get to learn things from people that you would not know”
In today’s episode, Dr Vikas Trivedi, a group leader at EMBL Barcelona, is interviewed by PhD student Prudence Lui. Vikas talks about his scientific journey and his research on using embryonic organoids to study self-organisation of cells. He describes the challenge in this field to use interdisciplinary approaches to study complex biological phenomena. He discusses the benefits of developing broad multidisciplinary expertise at the lab. As a group leader in science, he finds problem solving, working with intelligent people and contributing to other people’s career very rewarding. We also get to learn about Vikas’s interests beyond the lab. To find out more about Vikas's research, check out the following link: https://www.embl.org/groups/trivedi/
Episode 140- Dr Emma Rawlins "I'll look at stem cell in any systems"
In today’s episode, Dr Emma Rawlins, a senior group leader at the Gurdon Institute in University of Cambridge. She is interviewed by PhD student Elena Drudi. Emma talks about her research on stem cells in mammalian lungs using both mouse and human organoid models. She discusses the pros and cons of the two models. She describes her research interest in understanding normal embryonic lung development, with the aim to further repurpose these cues for lung repair/regeneration in adults. She emphasises how functional human genetics on a population level, in combination with human organoids models, can further help dissecting diseases susceptibility and regeneration. She also shares her journey from studying drosophila to human lung biology, and how going aboard no longer seems to be a necessity to continue one's career. To learn more about Emma’s recent postdoc work, check out the following links: https://www.gurdon.cam.ac.uk/research/rawlins
Episode 139 - Dr Vanessa Ribes - “We make bonds in thinking and developing ideas”
In today’s episode, Dr Vanessa Ribes, a group leader at Jacques Monod Institute, Paris, is interviewed by PhD student Victoria Tsang. Vanessa talks about her research on embryonic development of the spinal cord, its transcriptional regulation, the pathology of related congenital diseases, as well as cancers. She describes her long-time passion for biology and how she went from marine biology to agriculture to her current research. She discusses how meeting patients motivated and influenced her work. She shares her favourite aspects of being a scientist and her future focuses. She emphasises the importance of pleasure in pursuing a scientific career. To find out more about Vanessa's research, check out the following link: https://www.ijm.fr/en/864/research-groups/transcriptional-networks.htm
Episode 138 - Dr Carla Mulas - "Beyond mapping cell states and identities"
In today’s episode, Dr Carla Mulas, a postdoc in Stem Cell Institue at Cambridge University, is interviewed by PhD student Haneen Alsehi. Carla talks about her amazing research using biophysics to understand cell state transition. She discusses her journey in transiting from a biochemistry background to studying stem cells and their fate commitment, and her keen interest in how stem cells change their properties during differentiation. She talks about the challenge of the current cell state transition field in the need to go beyond mapping cell states and cell identities. She also shares her career insights in identifying what one wants to learn and the necessity of a good mentor. To find out more about Kristina's research, check out the following link: https://sites.google.com/view/cmulasresearch
Episode 137 - Dr Kristina Haase - "These vessel systems are so beautiful!"
In today’s episode, Dr Kristina Haase, a group leader at EMBL Barcelona, is interviewed by PhD student Prudence Lui. Kristina talks about her amazing research on bioengineered vascular networks and what kept her motivated to work on this for years. She discusses some challenges to be considered when generating advanced vascularised experiment models. She shares her fruitful experience of doing research across continents and in different areas. She emphasises the importance of having a clear biological question when doing science. We will also learn something about Kristina outside of the lab! To find out more about Kristina's research, check out the following link: https://www.embl.es/research/unit/haase/index.html
Episode 136 - Dr. Dominika Dziedzicka- "Differentiation propensity"
On today’s episode, Dr Dominika Dziedzicka, a postdoc working with Prof Ludovic Vallier from MRC Cambridge Stem Cell Institute. She is interviewed by Daria Belokhvostova, a PhD student in Centre of Stem Cells & Regenerative Medicine in King’s College London. Dominika talks about her PhD and recent postdoc work on human embryonic and induced pluripotent stem cells. She discusses the differences between differentiation propensity and differentiation potential of stem cells. To learn more about Dominika’s recent postdoc work, check out the following links: https://www.stemcells.cam.ac.uk/people/pi/vallier
Episode 135 - Ieva Berzanskyte - "When I started understanding it more I grew fond of it."
In today’s episode, Ieva Berzanskyte, our own graduating PhD student at the Centre for Stem Cells and Regenerative Medicine at King’s College London, is interviewed by PhD student Inês Tomás. Ieva talks about her exciting work on growing stem cells from patient tissues, then turning them into neurons to find a cure for spinal cord injury. She shares her thoughts on how the neuroscience field can speed up the discovery and translation of therapies into clinics. Following her deep interest in advancing biotechnologies, she discusses her upcoming post-doctoral research on the direct conversion between different cell types and its application. To find out more about Ieva’s experience check out the following link: https://www.regenerativemedicinephd.co.uk/student-profiles/ieva-berzanskyte
Episode 134-Prof Michael Levin-"Learn the best and put them together in your own way"
On today’s episode, Prof Michael Levin, a renowned regenerative and developmental biologist of Tufts University and Wyss Institute at Harvard University, is interviewed by Dr Davide Danovi, a group leader in Centre of Stem Cells & Regenerative Medicine in King’s College London. Mike talks about his multi-disciplinary work in decoding bioelectrical signals of cells, in particularly how information is stored, processed and used for functions within the biological system. He discusses how this biological knowledge can give rise to applications in machine learning and artificial intelligence. He also shares his view on ways to communicate across different disciplines, and how to be equipped for a multi-disciplinary mindset and skillsets. To learn more about Mike’s work, check out the following links: https://wyss.harvard.edu/team/associate-faculty/michael-levin-ph-d/ and https://ase.tufts.edu/biology/labs/levin
Episode 133 – Ana Pombo – “Every day I learn something.”
In today’s episode, Prof Ana Pombo, group leader at the Max Delbrück Center for Molecular Medicine in Berlin, is interviewed by PhD student Vasiliki Salameti. Ana talks about her pioneering work that enabled scientists to dissect how the genome is packaged inside cells and how this method is evolving with new single-cell technologies. She shares her view on future technology development which should help us make predictions. She discusses collaboration in science and the importance of timing in making research decisions. To learn more about Ana’s work check out the following link: https://www.mdc-berlin.de/pombo
Episode 132 – Nicolas Rivron – “By understanding the embyro, you understand regeneration.”
On today’s episode, Dr Nicolas Rivron, group leader at the Institute of Molecular Biotechnology, Austrian Academy of Science, is interviewed by PhD student Sergi Junyent Espinosa. Nicolas discusses his research building stem-cell based embryo models. He talks about the self-organising nature of tissue development in the embryo and how this can help us understand key principles of regeneration. For more information on Nicolas’ work check out the following link: https://www.oeaw.ac.at/imba/research/nicolas-rivron
Episode 131 - Vivian Li - “I felt like the intestine is actually quite a beautiful system.”
On today’s episode, Dr Vivian Li, group leader of the Stem Cell and Cancer Laboratory at the Francis Crick Institute, is interviewed by PhD student Elena Drudi. Vivian talks about her background in plant biotechnology, colon cancer research and working in Hans Clevers lab and her current research focus using human gut organoids to ask how stem cells are maintained in healthy guts, what happens when it goes wrong, and the Wnt signalling pathway’s role in this. She also talks about the future of engineering parts of the bowel to replace damaged and missing bowel. For more information on Vivian’s work check out the following link: https://www.crick.ac.uk/research/labs/vivian-li
Episode 130 - Derk Ten Berge - "It does require some bravery to spend the time to look for that"
In today’s episode, Dr Derk ten Berge, an Associate Professor in the department of Cell Biology at Erasmus MC University Medical Center Rotterdam, is interviewed by PhD student Daria Belokhvostova. Derk discusses his research on embryonic development and pluritpotency (the ability of a stem cell to make all the cells of the embryo) and the mechanisms of how cells become pluripotent. He talks about an intermediate stage of embryonic development called rosette stem cells. He considers about how his lab is dealing with the impact of Covid.
Episode 129 - Ana-Maria Cujba - "I think my passion is for organoids."
Ana-Maria Cujba, a PhD student at the Centre for Stem Cell's and Regenerative Medicine at King's College London, is interviewed by PhD student Ella Hubber. Ana-Maria discusses her work using human induced pluripotent stem cells and pancreatic organoids to study a new mechanism in mature onset diabetes of the young (MODY). She dives into the development of pancreatic organoids and making a more physiologically relevant system. She also discusses publishing her work as a PhD student and transitioning from a PhD to a post-doc. To learn more about Ana-Maria's work, check out the following links: https://www.regenerativemedicinephd.co.uk/student-profiles/ana-maria-cujba https://orcid.org/0000-0003-3917-6751
Episode 128 - Prof Muzlifah Haniffa - "We are going to map the 37 trillion cells in the human body."
Professor Muzlifah Haniffa, Professor of Dermatology and Immunology at Newcastle University, is interviewed by researcher Dr Clarisse Ganier. Muzz talks about her pioneering work in the fields of dermatology, immunology and genomics. She discusses her involvement in the human cell atlas, that aims to map all the cells of the human body. Muzz also speaks about the importance of public engagement in research science. To learn more about Muzz's work visit the following link: https://www.ncl.ac.uk/medical-sciences/people/profile/mahaniffa.html
Episode 127- Prof Francesco Saverio Tedesco - “Seeing patients gives you the right motivation.”
Prof Francesco Saverio Tedesco, Professor of Neuromuscular Biology and Regenerative Medicine at University College London, is interviewed by researcher Dr Davide Danovi. Francesco talks about his work using stem cells to understand and develop new therapies for muscular diseases such as muscular dystrophy. He speaks about the balance between his professions as a clinician and a scientist, and how this supports the translational goal of his research. To learn more about Francesco 's work visit the following link: https://www.ucl.ac.uk/biosciences/people/saverio-tedesco P.S. check out our new logo, designed by PhD student Matt Chung!
Episode 126 - Dr Madeline Lancaster - "It was a classic story of scientific serendipity"
Dr Madeline Lancaster, Group Leader at the Cell Biology Division of the MRC Laboratory of Molecular Biology in Cambridge, is interviewed by PhD student Ella Hubber. Madeline talks about the chance discovery and ongoing development of cerebral organoids and their use in studying human brain development and size differences between human and non-human apes. She also touches on the importance of engaging with the public as a scientist. To learn more about Madeline's work visit the following link: https://www2.mrc-lmb.cam.ac.uk/groups/lancaster/
Episode 125 - Dr Jürgen Knoblich- “Studying the brain is like studying oneself.”
On today’s episode, Dr Jürgen Knoblich, scientific director at the Institute of Molecular Biology at the Austrian Academy of Sciences, is interviewd by PhD student Sergi Junyen. Jürgen talks about his research journey to studying brains, the benefits of using fruit flies (Drosophila) in research, and the development and future of cerebral organoids, including their use in genetic screening. To find out more about Jürgen’s research follow this link: https://www.imba.oeaw.ac.at/research/juergen-knoblich/team/
Episode 125 - Dr Randolph Ashton - "I have faith in the cells, they can do a lot themselves."
Randolph Ashton, Associate Professor of Biomedical Engineering at University of Wisconsin-Madison, is interviewed by PhD student Ieva Berzanskyte. Randolph discusses his research engineering novel materials and methodologies to direct stem cell behaviour in a reproducible and scalable manner. He talks about how harnessing the natural ability of cells to differentiate can be used to develop models and scaffolds for regenerative medicine. To find out more about Randolph’s work please visit the following website: https://directory.engr.wisc.edu/bme/Faculty/Ashton_Randolph/
Episode 124 - Prof Weiss - "When I realised we could programme cells, I knew it is what I had to do"
Today Ron Weiss, Professor in the Department of Biological Engineering and in the Department of Electrical Engineering and Computer Science at the Massachusetts Institute of Technology and Director of the Synthetic Biology Center at MIT, is interviewed by PhD student Matt Chung. Ron is a pioneer in the field of synthetic biology, using computer engineering principles to program cells to be controlled by analog and digital logic circuitry. He discusses how synthetic biology can be translated into clinical benefit for a wide range of diseases, including cancer. He talks about the challenges of building reliable networks that are robust to environmental change, a key challenge in the clinical translation of synthetic biology approaches. To find out more about Ron’s work please visit the following website: https://weiss-lab.mit.edu/
Episode 123 - Prof Manuel Serrano - "Understanding aging can help treat other diseases."
Today, Professor Manuel Serrano from the Institute for Research in Biomedicine in Barcelona is interviewed by PhD student Emily Read. Manuel has produced seminal work in the fields of tumour suppression, senescence, ageing and reprogramming. In this episode he talks about the link between senescence and regeneration, and how this can become disrupted in disease and ageing. He discusses how targeting senescent cells can prolong lifespan and reflects on the impactions of this on wider society. To find out more about Manuel’s work please visit the following website: https://www.irbbarcelona.org/en/profile/manuel-serrano
Episode 122- Prof Matthias Lütolf - "Organoids give us a new window into human biology."
Today, Professor Matthias Lütolf, Head of the Laboratory of Stem Cell Bioengineering at The École polytechnique fédérale de Lausanne is interviewed by PhD student Emily Read. Matthais talks about how scientists can begin to build human diseases in a dish using organoid technologies. He discusses the importance of understanding how physical factors can influence stem cell behaviour and how this can be studied with engineering approaches. To find out more about Matthias’ work please visit the following website: https://people.epfl.ch/matthias.lutolf/bio?lang=en
Episode 121 - Prof Kevin Eggan - "Science progresses through replication, validation, extension"
Today, Professor Kevin Eggan from the Department of Stem Cell and Regenerative Biology at Harvard University, is interviewed by PhD student Peter Harley. Kevin talks about the difficulties of studying neurodegenerative disorders and applying stem cell technologies to study motor neuron disease/ALS. He discusses why highlighting and understanding contradictory findings is an essential part of scientific research and the reliability of using mouse models to study ALS. To find out more about Kevin’s work please visit the following website: https://hsci.harvard.edu/people/kevin-c-eggan-phd
Episode 120 - Prof Salvador Benitah - "I still have to sit down and learn new things"
Prof Salvador Aznar Benitah, ICREA Research Professor at Institut de Recerca Biomèdica, is interviewed by PhD student Victoria Tsang. Salvador talks about his research understanding the molecular pathways that dictate stem cell behaviour, including his recent work on the role of dietary fats, and how this goes wrong in cancer. He talks about recent advances in the field of oncology and the challenges they pose to clinical translation. For more information on Salvador's research follow this link: https://www.icrea.cat/Web/ScientificStaff/salvador-aznar-benitah-408
Episode 119 - Prof Alfonso Martinez Arias - "The 21st Century is the Century of the Cell."
Professor Alfonso Martinez Arias, professor of developmental mechanics in the department of genetics at the University of Cambridge, is interviewed by PhD student Alice Vickers. Alfonso discusses the applications, ethical considerations, legislation, and difficulties of progressing his research using embryonic stem cells as a model system for studying human development. He also looks back at the experiences and experiments that hooked him on answering the vital question of how a single cell becomes a whole organism. For more information on Alfonso's research follow this link: https://www.gen.cam.ac.uk/directory/alfonso-martinez-arias
Episode 118 - Prof Trepat - "The biggest questions of our generation are in life sciences"
Professor Xavier Trepat, ICREA Research Professor at Institut de Bioenginyeria de Catalunya, is interviewed by PhD student Sebastiaan Zijl. Xavier talks about his work understanding how physical forces impact how cells grow, move and behave. He discusses the coolest experiment he has ever done and how lockdown has unexpectedly benefited his lab. For more information on Xavier's research follow this link: https://www.icrea.cat/Web/ScientificStaff/xavier-trepat-534
Episode 117 - Prof Peter Zandstra - "We are bringing technology and biology together"
Professor Peter Zandstra, Director of the Michael Smith Laboratories at The University of British Columbia, is interviewed by Group Leader Dr Davide Danovi. Peter talks about his work understanding blood development from stem cells and how this can be used improve therapeutics for diseases such as leukaemia. He discusses his beginnings as a chemical engineer and how this has shaped his career path. For more information on Peter's research follow this link: https://www.msl.ubc.ca/people/dr-peter-zandstra/
Episode 116 - Dr William Grey - Are proteins the key to understanding cancer?
Dr William Grey, a post doctoral researcher in the Haematopoietic Stem Cell Laboratory at the Francis Crick Institute, is interviewed by PhD student Jana Obajdin. William talks about using umbilical cord blood in the treatment of genetic disorders and the future of cancer therapies. He also tells us why the study of proteins is an exciting and expanding field, particularity in cancer research. For more information on William's research follow this link: https://www.crick.ac.uk/research/find-a-researcher/william-grey Donate your umbilical cord blood with Anthony Nolan: https://www.anthonynolan.org/8-ways-you-could-save-life/donate-your-umbilical-cord
Episode 115 - Prof James Briscoe - Where does time come from in development?
Prof James Briscoe, group leader of the Developmental Dynamics Lab at the Francis Crick Institute, is interviewed by PhD student Ieva Berzanskyte. James talks about his research into the developing spinal cord and thinks about what is currently fascinating him, including understanding the "tempo" of embryonic development. For more information on James' research follow this link: https://www.crick.ac.uk/research/labs/james-briscoe
Episode 114 - Prof Janet Rossant - "Science is going to get us out of this, science is the answer."
Prof Janet Rossant, Senior Scientist on the Developmental & Stem Cell Biology Program, Chief of Research Emeritus at the SickKids Research Institute, President and Scientific Director of the Gairdner Foundation and Professor in the Departments of Molecular Genetics and Obstetrics & Gynaecology at the University of Toronto, is interviewed by PhD student Geraldine Jowett. Janet discusses her work characterising embryonic development and applying this to generate stem cell models. She talks about the importance of the terminology and language used surrounding embryo research, as well as how her lab is contributing to the COVID response. For more information on Janet's research follow this link: https://lab.research.sickkids.ca/rossant/
Episode 113 - Prof Olivier Pourquié - "I think pretty much every bit of Biology is interesting."
"It’s a mindset." Prof Olivier Pourquié, Professor of Pathology and Professor in the Department of Genetics at Harvard Medical School, is interviewed by PhD student Ella Hubber. Olivier breaks down how spinal vertebrae are formed in the embryo through a “segmentation clock” and how understanding this is relevant to human disease. He also talks about the significant changes in developmental biology over the course of his career. For more information on Olivier's research follow this link: https://hsci.harvard.edu/people/olivier-pourqui%C3%A9-phd
Episode 112 - Prof Cristina Lo Celso - "At the time stem cells seemed like the holy grail."
Prof Cristina Lo Celso, Professor of Stem Cell Biology and group leader at Imperial College London, is interviewed by PhD student Elena Drudi. Cristina discusses her work visualising blood stem cells and determining the factors that control their function, to better understand mechanisms underlying blood based cancers. She also talks about her career progression and the importance for her of travelling between countries. For more information on Cristina's research follow this link: https://www.imperial.ac.uk/people/c.lo-celso
Episode 111 - Dr Ivo Lieberam - "How we are going to interact with technology in the long term?"
We return this week to an episode recorded during lockdown. Dr Ivo Lieberam, Senior Lecturer and group leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Eva Hamrud. Ivo discusses his work on generating neuromuscular models in a dish that can be used to understand neuromuscular diseases and screen novel therapies. He also discusses his long term aim to generate technologies, such as light controlled medical devices and biorobots, that could be used in the future to treat a range of diseases. For more information on Ivo's research follow this link: https://www.kcl.ac.uk/lsm/research/divisions/gmm/departments/stemcells/people/dr-ivo-lieberam
Episode 110 - Dr Francesca Spagnoli- "We study biological problems with direct medical application."
We return this week with an episode recorded during lockdown. Dr Francesca Spagnoli, Group Leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Teodora Manea. Francesca discusses her group's research on understanding how pancreatic beta cells communicate with their environment and the possibility of converting liver cells to pancreas cells, with the aim of applying this to cell replacement therapies in the treatment of diabetes. She also talks about studying mouse and human pancreatic development and learning from a comparative approach. For more on Francesca's research, follow this link: https://www.spagnolilab.org/
Episode 109 - Prof James Sharpe - "You were limited by nothing but your own imagination."
We return this week with an episode recorded during lockdown. Prof. James Sharpe, the head of EMBL Barcelona, is interviewed by PhD student Sergi Junyent. Prof. Sharpe is one of the key opinion leaders in developmental biology and bioengineering. Here, he talks about the pioneering work done by his group in understanding tissue development and discusses his how his work brings together his passion for computer programming and biology. For more information on Prof. Sharpe's research follow this link: https://www.embl.es/research/unit/sharpe/members/index.php?s_personId=CP-60027035
Episode 108 - Prof Jianping Fu - “Human development itself is just fascinating.”
“Even just to understand the genesis of human being itself... It must be one of the holy grails of modern biology.” We return this week with an episode recorded during lockdown. Professor Jianping Fu, a professor of Mechanical Engineering, Biomedical engineering and Cell and Developmental Biology at the University of Michigan, is interviewed by PhD student Sergi Junyent. He talks about the technical difficulties and ethical issues of studying human development. He discusses the growing field of stem cell based embryo models to study the early stages of development and the future directions of these models. For more information on Jianping's research follow this link: http://me-web.engin.umich.edu/ibbl/
Episode 107 - Prof Ludovic Vallier - "The drive is to generate more knowledge."
We return this week with an episode recorded during lockdown. Professor Ludovic Vallier, Professor of Regenerative Medicine within the Department of Surgery at Cambridge University and director of the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre hIPSCs (human induced pluripotent stem cells) core facility, is interviewed by PhD student Alice Vickers. He talks about his work using human pluripotent cells to generate pancreas, lung, gut and liver cells. He speaks about how his involvement in industry aims to generate cell types for clinical studies and for cell based therapy. For more information on Ludovic's research follow this link: https://www.stemcells.cam.ac.uk/People/pi/vallier
Episode 106 - Professor Peter Jones - "I think all scientists are curious by nature."
We return this week with an episode recorded during lockdown. Professor Peter Jones, Professor of Endocrine Biology and head of the Department of Physiology at King's College London, is interviewed by PhD student Prudence Lui. Peter breaks down the basics of type 1 and type 2 diabetes and discusses his lab's recent research into the phenomenon of mitochondrial transfer. After 36 years at King's, Peter talks about what has kept him in scientific research. For more information on Peter's research follow this link: https://www.kcl.ac.uk/people/peter-jones
Episode 105-Dr Norah Fogarty-"Understanding the placenta we may treat disease before manifestation"
We return this week to an episode recorded during lockdown. Dr Norah Fogarty, a new group leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Geraldine Jowett. Norah discusses her work on the development of the trophectoderm in the human embryo, which is the progenitor of early placental cells. She talks about how this work aims to further our understanding of human embryo development and early pregnancy loss, and may in the future lead to advances in assisted reproductive treatments. For more information on Norah's research follow this link: https://kclpure.kcl.ac.uk/portal/norah.fogarty.html
Episode 104 - Dr Alejo Rodriguez-Fraticelli - “What’s important is keeping an open mind.”
Today on the SC@L Digested Podcast, Post-doc Miguel Bernabe-Rubio speaks with Alejo Rodriguez-Fraticelli, a research fellow at the Boston Children’s Hospital and soon-to-be principal investigator at the Institute for Research in Biomedicine in Barcelona. Alejo talks about his work using single cell maps to understand highly variable populations of cells and his future research focus on acute myeloid leukaemia. He also talks about developing his skills in computational biology through collaboration and the importance of stepping out of your comfort zone to succeed in interdisciplinary research. To see more of Alejo's research, follow this link: https://connects.catalyst.harvard.edu/Profiles/display/Person/176343
Episode 103 - Dr Victor Negri - A Lockdown Story
“Take care of yourself, but also be aware of others who are more vulnerable than you” For this episode of SC@L digested, CSCRM public engagement officer Jessica Sells chatted with Victor Negri, A Post Doc in Fiona Watt’s lab, about his experience of lockdown. We've been exploring the impact that lockdown is having on our researchers by asking them to share their experiences. All of our staff are in unique positions, meaning lockdown is affecting their personal and work lives dramatically differently. For Victor the pandemic has been quite scary, as he has to take daily immunosuppressants for a health condition. He tells us how this has made him feel, and also his thoughts on how this situation will hopefully make the public take science more seriously... For more examples of our lockdown stories, visit the Watt Lab Blog here: www.wattlab.org
Episode 102- Geraldine Jowett- "There's something valuable about coming together and sharing values"
We return this week to an episode recorded during lockdown. Geraldine Jowett, a final year PhD student on the Wellcome Trust Cell Therapies and Regenerative Medicine programme at King's College London, is interviewed by PhD student Emily Read. Geraldine discusses her work that uses stem cells to make mini-intestine in a dish models, also known as organoids, to understand Inflammatory Bowel Disease. She talks about the difficulties of an interdisciplinary PhD and what she has learnt moving between Germany, the United States and Britain. For more information on Geraldine's research follow this link: https://www.kcl.ac.uk/people/geraldine-jowett
Episode 101 - Dr José Silva - "It is the basic research that leads to applied science."
We return this week to another interview recorded before lockdown. PhD student Christopher Lambert interviews Dr José Silva, a group leader at the Welcome-MRC Cambridge Stem Cell Institute. Dr Silva tells us about his career path from PhD to group leader and his current research in cellular reprogramming. They discuss the importance of collaboration in basic research and the need for a long-term, step-wise approach to progress the field of cellular reprogramming. Dr Silva also looks to the future, talking about his move into creating synthetic embryos. For more information about Dr Silva's research, follow this link: https://www.stemcells.cam.ac.uk/People/pi/silva
Episode 100 - Professor Fiona Watt - A Lockdown Story
For our 100th SC@L episode, we've done something a bit different... We've been exploring the impact that lockdown is having on our researchers by asking them to share their experiences. All of our staff are in unique positions, meaning lockdown is affecting their personal and work lives dramatically differently . For this Lockdown Story, Public Engagement Officer Jess Sells remotely interviews CSCRM Director and MRC Exec Chair Professor Fiona Watt. Fiona talks about how she has been maintaining a work-life balance, thoughts on how this situation will change science, and society in general. For more examples of our lockdown stories, visit the Watt Lab Blog here: https://www.wattlab.org
Episode 99- Prof Susan Kimber- "Having stamina is probably more important than having brains"
We return this week to another interview recorded before lockdown. Professor Susan Kimber, Professor of Stem & Developmental Biology at University of Manchester, speaks to PhD student Peter Harley. She discusses her work that uses human stem cell models to understand human development and to model vascular, skeletal and kidney diseases in a dish. She talks about how human stem cell models are important for both basic and translational science. When asked what makes a successful scientific career, she discusses the important of stamina and resilience. For more information on Professor Kimber's research follow this link: https://www.research.manchester.ac.uk/portal/sue.kimber.html
Episode 98 - Dr Nathan Hawkshaw - Does the immune system affect hair growth?
On this episode of the SC@L Digested Podcast, we return to an interview recorded before lockdown. PhD student, Inchul Cho, speaks to Dr Nathan Hawkshaw, a research associate in the Division of Musculoskeletal & Dermatological Sciences at the University of Manchester. They discuss how immunosuppressants could promote human hair growth and treat hair loss and consider how the immune system is involved in hair cycling. They also discuss Dr Hawkshaw's current research into the effects of ultra-violet radiation on the skin. For more information on Dr Hawkshaw's research follow this link: https://www.research.manchester.ac.uk/portal/nathan.hawkshaw.html
Episode 97 - Dr Simon Mendez Ferrer - How can targeting where stem cells live help transplants?
Today on SC@L digested PhD Student Dr Beibei Du speaks with Dr Simón Méndez-Ferrer, a Reader in Transfusion Medicine at the University of Cambridge. They discuss what controls blood stem cell behaviour, including whether you are awake or asleep. Simón also talks about how understanding what makes blood stem cells move can be used in stem cell transplants to treat blood cancers. For more information on Simón's research, follow this link: http://www.haem.cam.ac.uk/staff/senior-staff/dr-simon-mendez-ferrer/
Episode 96 - Dr David Willnow - How can we treat diabetes with liver cells?
For this episode of SC@L we’ve given remote recording a go to keep producing the podcast on lockdown! PhD student Ana Maria Cujba interviews Dr David Willnow from the Spagnoli Group at the CSCRM. They discuss his research into how the pancreas develops in the embryo and how this will develop potential future therapies for diabetes with this knowledge, David’s involvement multidiciplinary Pan3dp initiative , and the challenges of the immune response to regenerative cell therapies. For more information on David's research and the Spagnoli Lab, follow this link: https://www.spagnolilab.org
Episode 95 - Prof Fiona Watt - "Everything I do is hard-wired with the scientific mind set"
For this extra special episode of SC@L digested, we are joined by CSCRM Director and MRC Executive Chair Professor Fiona Watt! Her PhD student Dr Xinyi (Beibei) Du speaks to her about her career path, what factors have helped her on her journey to success, her experiences of being a prominent woman in science and how we can support women in science. For more information on Professor Watt’s research follow this link: https://www.kcl.ac.uk/people/fiona-watt
Episode 94 - Prof Buzz Baum - How do cells do the things they do?
This episode of Stem Cells @ Lunch Digested features Professor Buzz Baum from UCL. PhD student Sergi Junyent talks to him about his passion for cells and the process of their division, and the importance of answering biological questions with multidisciplinary tools and teams. For more information about his research follow this link: https://www.ucl.ac.uk/lmcb/users/buzz-baum
Episode 93 - Alice Vickers- What is a good science investment?
For today’s special episode of SC@L, Vasi Salameti interviews fellow CSCRM PhD student Alice Vickers about her recent experience doing an industry placement as part of her PhD. Alice spent 6 months working as an analyst at M Ventures based in Amsterdam, the venture capital arm of Merck Industries. Hear all about what she got up to, how industry differs from academia, how VC’s assess pitches, and why the process from bench to drug production takes time... (All views expressed by Alice in this interview are her own and do not reflect those of M Ventures or Merck KGaA)
Episode 92 - Dr Oliver Pearce - How can we enable the body to kill cancer?
Today on SC@L digested, PhD student Sam Blackford speaks with Dr Oliver Pearce and his journey transitioning from chemistry to cancer immunotherapy. They discuss the role of the extracellular matrix in tumour development, what immunotherapy is and what techniques his lab are using to model cancer and explore potential therapeutic approaches... For more information about Dr Pearce's research follow this link:https://www.bartscancer.london/staff/dr-oliver-m-pearce/
Episode 91 - Dr Teresa Rayon - Can we modulate the speed of differentiation?
For this weeks’ episode of SC@L digested, Dr Lea R’Bibo is joined by Dr Teresa Rayon from The Crick. They talk about what the neural tube is, and how stem cells can be used to study it. Dr Rayon also explains her interest in the difference in speed of embryonic development across different species, and why it is important to understand these processes. She also emphasises the benefit of working in different labs and cultures, and why it is so important to share your research with the public... For more information about Dr Rayon''s research follow this link: https://www.crick.ac.uk/research/find-a-researcher/teresa-rayon-alonso To listen to her podcast click here: https://sruk.org.uk/initiatives/public-engagement/en-fase-experimental/
Episode 90 - Professor Julien Gautrot - How do cells interact with biomaterials?
EPISODE 90 For this week’s episode of Stem Cells @ Lunch Digested, PhD student Prudence Lui interviews Professor Julien Gautrot about his research into how cells interact with biomaterials, how has nature helped develop biomaterials, and what the best part of his job is. For more information on Prof. Gautrot’s work follow this link: https://www.sems.qmul.ac.uk/staff/research/j.gautrot
Episode 89 - Dr David Gershlick - How do cells work?
In today’s SC@L digested episode Dr Lea R’Bibo interviews Dr David Gershlick at the institute of medical research at Cambridge! His research area is protein trafficking – how cells organise themselves and how the parts inside a cell move around to help it function. They discuss applications and challenges of this research, and how he has found the transition from postdoc to PI... For more information on Dr Gershlick's research follow this link: https://www.cimr.cam.ac.uk/research/principal-investigators/gershlick
Episode 88 - Professor Jeremy Green - How do cells form tissues?
This week we are joined by Professor Jeremy Green from the Centre for Craniofacial and Regenerative Biology at King’s College London. He talks to PhD student Thea Willis about his career path, his group’s research looking at how cells physically form structures such as tissues, and what got him interested in the work he is doing. He also has a few tips for PhD students....
Episode 87 - Dr Adrian Biddle - Oral Cancer Invasion.... How does it happen?
Oral Cancer Invasion... How does it happen? In today’s SC@L digested podcast, PhD student Inês Tomás talks to Dr Adrian Biddle, lecturer at the Blizard Institute, Queen Mary University of London, investigating the role of cancer stem cells in oral cancer. Together they talk about the differences between different types of cancer stem cells, finding a common problem in oral cancer to target as a treatment, different cancer model systems, and the potential future of cancer research.... For more information on Dr Adrian Biddle's work follow this link : https://www.qmul.ac.uk/blizard/staff/centre-for-cell-biology-and-cutaneous-research/staff/adrian-biddle.html
Episode 86 - Dr John Connelly - Homeostasis: What happens when this process is disrupted?
Today on SC@L digested PhD student Blaise Louis interviews Dr John Connelly from the Institute of Bioengineering from Queen Mary University of London. They talk about how he uses bioengineering tools and biomaterials to study the biology of how cells manage the process of homeostasis and the tissue maintains itself, and what happens when these processes are disrupted. They also talk about the future of biomaterials and how Dr Connelly is starting to use more complex 3D models of the skin for his research and what that means for understanding how whole tissues function. For more information about Dr Connelly's work follow this link: https://www.bioengineering.qmul.ac.uk/people/?j.connelly
Episode 85 - Dr Mohi Ahmed - What is Epigenetics?
For this episode of SC@L digested we are joined by Dr Mohi Ahmed, from the Craniofacial Development & Stem Cell Biology dept at King’s College London. He talks to PhD student Ieva Berzanskyte about what epigenetics is, how he is investigating hearing loss via epigenetic mechanisms, and how to develop potential treatments for this… For more information on his research please follow this link: https://kclpure.kcl.ac.uk/portal/mohi.1.ahmed.html
Episode 84 - Emma Milford - How do cancer Cells Interact with their environment?
For today’s episode of SC@L digested, PhD student Jana Obajdin talks to Emma Milford, a PhD student at the Francis Crick Institute. They discuss her project investigating how cancer cells interact with their environment, including how they respond to different types of treatments… For more information about Emma follow this link: https://www.crick.ac.uk/research/find-a-researcher/emma-milford
Episode 83 - Dr Malte Kunhemund - Single Cell Spatial Mapping with Cartana
In today’s SC@L episode, PhD student Dr Xinyi (Beibei) Du gets excited about single cell transciptomics with Malte Kühnemund, CEO and Co-Founder of Cartana. They discuss how he transitioned from PhD to developing his single cell spatial mapping technology, how it works, and whether he misses academia now that he’s a biotech CEO! For more info about Cartana follow this link: https://www.cartana.se
Episode 82 - Sergi Junyent - How do stem cells organise themselves?
For this podcast episode , PhD student Daria Belhokvostova interviews Sergi Junyent about his current PhD project exploring how stem cells organise themselves during embryonic development, what signals cells exchange in this process, and what his experience of doing a PhD has been like!
Episode 81 - Dr Carrie Ambler - Minds of Their Own: How do cells make choices?
For this episode of SC@L digested, PhD student Wladislaw Stroukov Interviews Dr Carrie Ambler from Durham University. They spoke about her work at the university looking at how cells make decisions, and what drugs or chemicals can be used to alter these choices. She also tells us about her spin off company LightOx that does interesting things with light to track and destroy cells..... For more information about her research follow this link: https://www.dur.ac.uk/biosciences/about/schoolstaff/profile/?id=5554
Episode 80 - Dr Mike Delahaye - Making stem cell therapies more cost efficient and effective
For this week’s episode, Dr Davide Danovi speaks with Dr Mike Delahaye, Lead Technical Scientist from the Cell and Gene Therapy Catapult based at Guy’s Hospital. Dr Delahay talks about what gene therapy and viral vectors are, his work trying to increase their efficiency, and his experience working at the Catapult the last 6 years…. Find out more about Mike Delahaye and Cell and Gene Therapy Catapult here: https://ct.catapult.org.uk/how-we-work/vacancies/our-people
Episode 79 - Dr Pervinder Sagoo - Optimising gene therapies for rare diseases
For this episode of stem cells @ lunch digested, PhD student Vassia Salameti interviews Dr Pervinder Sagoo, Senior Scientist at Orchard Therapeutics - a biopharmaceutical company developing stem cell gene therapies for rare diseases. Dr Sagoo talks about how she got into this role, her career path that took her from academia to commercial science and what she thinks the future of gene therapies will be…
Episode 78 - Dr Leandro Ventimiglia - The importance of imaging living cells
In this week’s episode of stem cells @ lunch digested, PhD Student Georgina Goss interviews Dr Leandro Ventimiglia, a Research Asociate at the KCL department of Infectious Diseases. He discusses his work looking at the mechanisms that control the morphology of the cell nucleus and what conditions arise when there are defects in this organelle, what imaging and microscopy techniques that he is using to visualise this, and what advice would he give to someone starting their career in research... School of Immunological and Microbial Sciences @kclimmuno @nikoncentre @nikon
Episode 77 - Dr Heiko Wurdak - How do stem cells help to understand brain tumors?
Today’s episode of SC@L digested features Dr Heiko Wurdak, Lecturer at the University of Leeds, interviewed by PhD student Ieva Berzanskyte. Ieva asks how stem cells help him to model brain tumors in the lab and how his research could help develop future treatments for brain tumors… For more information on his research follow this link:https://medicinehealth.leeds.ac.uk/medicine/staff/905/dr-heiko-wurdak
Episode 76 - Dr Tamas Korcsmaros
Today’s episode of SC@L digested sees Public Engagement Officer Jessica Sells interview Dr Tamas Korcsmaros, Group Leader at both the Earlham & Quadram Insititutes. He talks about how he uses organoids to investigate how the microbiome influences our gut cells and health, the efficacy of superfood probiotics, and his involvement in outreach organisations such as the Hungarian and International Talent Support Programme. To find out more about Dr Korcsmaros work please follow this link:https://www.earlham.ac.uk/tamas-korcsmaros
Episode 75 - Dr Xinyi (Beibei) Du - Can mapping single cells lead to new acne treatments?
In this episode of Stem Cells @ Lunch digested, PhD student Ella Hubber interviews Clinical Research Fellow Dr Xinyi (Beibei) Du. She talks about how her dermatology training led her to start research skin as part of the Human Cell Atlas using single cell RNA sequencing, the importance of involving patients in research, and the transition from working in the clinic to the lab…
Episode 74 - Prof Nico De Leu
For this episode of SC@L digested, PhD student Ana Maria Cujba interviews Professor Nico De Leu from the University Hospital of Brussels. He talks about the challenges of combing clinical work and lab work, and his research on the role of a growth factor (VGFA) on the function of beta cells which produce insulin in the pancreas, and how the growth factor is involved in vascularisation of beta cell transplants for patients with diabetes...
Episode 73 - Dr Luca Urbani
This week’s episode of SC@L digested is all about the liver! CSCRM’s Public Engagement Officer Jessica Sells talks to Dr Luca Urbani about his work using tissue engineering to replicate functioning livers to study liver diseases and regeneration…. For more information of Dr Urbani's work please follow this link: http://www.liver-research.org.uk/ourstaff/luca-urbani.html
Wellcome Trust PhD 2018 Cohort.
In this special episode of Stem Cells @ Lunch Digested, CSCRM Public Engagement Officer Jessica Sells speaks to the Wellcome Trust "Cell Therapies and Regenerative Medicine" 4 year PhD programme 2018 cohort about their experience co-writing a review. The review titled: "Mechanisms, Hallmarks, and Implications of Stem Cell Quiescence" was published in Stem Cell Reports, and will be featured in the special June edition of the publication to tie in with the International Society for Stem Cell Research 2019 conference. The interview features Wladislaw Stroukov, Jana Obajdin, Prudence Lui, Thea Willis and Federica Riccio. Unfortunately, fellow cohort member Inchul Cho was unable to attend. Follow this link to read the full publication online: https://www.ncbi.nlm.nih.gov/pubmed/31189093
Episode 72 - Dr Kevin Chalut
How do stem cells decide to make copies of themselves or become something different? Does mechanical signalling influence how stem cells make decisions? How is the timing of these irreversible changes happen from a physics perspective? Hear Dr Kevin Chalut from the Cambridge Stem Cell Institute discuss his work in this field with PhD student Gabby Clarke. To find out more about his research follow this link: https://www.stemcells.cam.ac.uk/research/pis/chalut
Episode 71 - Professor Trevor Graham
For this episode of SC@L digested, PhD student Inês Tomás interviews Dr Trevor Graham from the Barts Cancer Institute about his career path, fusing mathematics and biology, difficulties in modelling cancer, and the hunt for the cure…. for more information about his research follow this link:https://www.bci.qmul.ac.uk/staff/item/trevor-graham
Episode 70 - Dr Kate Miroshnikova
In the latest episode of SC@L digested, PhD student Sergi Junyent interviews Dr Kate Miroshnikova from the Wikstrom Lab at the University of Helsinki. She talks about how she got into bioengineering, her PhD diagnosing cancer by the biophysical properties of cells, and her current work on how physical forces moderate stem cell differentiation...
Episode 69 - Dr Vasanta Subramanian
In today’s SC@L digested episode, PhD student Steph Hynes interviews Dr Vasanta Subramanian from the University of Bath, who talks about her career path and her work on the role of the protein TALPID3 in the development of cilia and rare diseases called ciliopathies, and how targeting this protein could lead to potential therapies for these conditions.... For more information about her research follow this link: researchportal.bath.ac.uk/en/persons/v…-subramanian
Episode 68 - Dr Anatoly Zayats
In this episode of SC@L digested PhD student Xinyi Du interviews Dr Anatoly Zayats from the London Nanotechnology Centre, who tells us about his interesting and international career path, what nano technology is & where you come across it in every day life, & how to apply it to healthcare and data processing... For more information about his research follow this link: https://www.kcl.ac.uk/nms/depts/physics/people/academicstaff/zayats
Episode 67 - Dr Clarisse Ganier
For today’s SC@L digested podcast episode, PhD student Daria Belokhvostova interviews Dr Clarisse Ganier, a post doctoral researcher who recently joined the Centre for Stem Cells & Regenerative Medicine. She talks about her PhD project developing potential therapies for the rare skin disease Recessive Dystrophic Epidermolyis Bullosa (RDEB), also known at butterfly skin, and her also her current work for the Human Cell Atlas project.
Episode 66 - Dr Rebecca Barlow
We have a special episode of SC@L digested for International Women's Day! Dr Rebecca Barlow, Strategy and Planning Manager at the Medical Research Council came and spoke to Jessica Sells about her career path and about setting up Women’s Networks, what they are and why they are important to have in the workplace.
Episode 65 - Professor Sami Barmada
This week's episode sees Dr Davide Danovi interview Professor Sami Barmada from the University of Michigan about his research into amyotrophic lateral sclerosis and frontotemporal dementia, and how stripping science back to basics can lead to big discoveries! For more information about his work please follow this link: https://medicine.umich.edu/dept/neurology/sami-barmada-md-phd
Episode 64 - Dr Guillaume Blin
Welcome to this week’s episode of stem cells at lunch digested. Today, PhD student Sergi Junyent interviews Dr Guillame Blin about his career history, growing cells on matrixes of various stiffness to see how cells differentiate and why he moved to Edinburgh to pursue his research on how embryos develop and organise their cells For more information about his research follow this link: http://www.crm.ed.ac.uk/people/guillaume-blin
Episode 63 - Dr Markus Diefenbacher
For this episode of SC@L digested, Jessica Sells speaks to Dr Markus Diefenbacher, a Principle Investigator from University of Würzburg. He talks about his career path in genetics, using patient data to model diseases, and the possibility of translating his work into potential treatments.... For more information about his work follow this link:https://www.uni-wuerzburg.de/grk2243/people/principal-investigators/markus-diefenbacher/
Episode 62 - Professor Oron Catts And Dr Ionat Zurr
This Week’s SC@L digested is a little bit different, featuring world renowned bio-artists and tissue engineering Research Fellows Oron Catts and Ionat Zurr. They talk about their fascinating journey of how and why they came into the world of bioart, their experience of working with scientists and learning their techniques, being the first people to grow and eat lab grown meat, and their latest installation for the upcoming Science Gallery London Spare parts season, supported by CSCRM researchers…
Episode 61 - Dr Adam Pennycuick
For our latest SC@L digested episode, Jessica Sells interviews respiratory Clinician and PhD student Adam Pennycuick about his diverse career path leading to his research into the early detection of lunch cancer, analysing 20 years worth of data from pre cancerous patients, and how outcomes of this research could potentially impact the public in future. He also talks about his most recent paper that just came out in Nature yesterday, follow this link to see it yourself: https://go.nature.com/2FRVi43
Episode 60 - Dr Sandrine Thuret
In this episode, Jessica Sells interviews KCL Principle Investigator and Lecturer Dr Sandrine Thuret about her international study and career path, investigating topics ranging from cereal coatings to hippocampal neurogenesis and lecturing her favourite subjects. She tells us why it is important to study how the brain makes new neurons, what the hot debate is within the field and whether attitudes towards women in science have changed much over the 12 years she has been running her own lab…. For more information about Dr Thuret's research follow this link: https://www.kcl.ac.uk/ioppn/depts/bcn/Our-research/Cells-behaviour/thuret-adult-neurogenesis/about.aspx
Episode 59 - Dr Siim Pauklin
This week’s episode sees PhD student Alice Vickers interview Dr Siim Pauklin from the Botnar Research Centre at Oxford University. He talks about about his research investigating cancer stem cells which can give rise to tumors, the importance of understanding them and their function and whether these cells are a potential target for cancer treatments.... For more information about Dr Pauklin's work follow this link: https://www.ndorms.ox.ac.uk/team/siim-pauklin
Episode 58 - Dr Chris Lorenz
In today’s podcast episode, CSCRM Public Engagement Officer Jessica Sells interviews Dr Chris Lorenz, Lecturer and Principle Investigator in the KCL Biological Physics & Soft Matter Group. He tells about his career path, his role using computer simulations to understand properties of materials, what hydrogels are and how they can be used in combination with stem cells….
Episode 57 - Professor Maddy Parsons
This week's episode sees CSCRM PhD student Geraldine Jowett interview Professor Maddy Parsons about her roles at King's (including Professor of Cell Biology and Scientific Director of the Nikon Imaging Centre)and her research into how cells stick to their environment and how that is involved in skin blistering diseases and cancer. Geraldine and Maddy also talk about the art of microscopy..... For more information about Professor Parsons see this link: https://kclpure.kcl.ac.uk/portal/en/persons/madeline-parsons(cccc6360-8192-45ae-b192-0133f7b69299).html
Episode 56 - Dr Eileen Gentleman
In today’s Stem Cells @ Lunch Digested, CSCRM PhD student Sebastiaan Zijl interviews Dr Eileen Gentleman. Eileen talks about her research combining materials with stem cells to grow 3D tissue to replace damaged or diseased tissues in patients. For more information about Dr Gentleman's work please see this link: https://kclpure.kcl.ac.uk/portal/eileen.gentleman.html
Episode 55 - Dr Nazia Mehrban
This week, Dr Inês Sequeira interviews Dr Nazia Mehrban about her career path spanning forensic science and criminology, to the development of biomaterials. She discusses how the smart materials she is developing will help to replace missing or diseased tissues for patients, and what her future plans are…. For more information about Dr Mehrban's work following this link: https://iris.ucl.ac.uk/iris/browse/profile?upi=NMEHR68
Episode 54 - Mr Sam Blackford
In Stem Cells @ Lunch Digested this week, PhD student Sergi Junyent interviews fellow CSCRM PhD student Sam Blackford. Sam talks about his experience studying in science so far, why he chose to work as a research assistant prior to taking on a PhD, and his research project exploring the possibility of using stem cells to treat liver diseases, and taking this to clinical trials. Sam completed his undergraduate degree at the University of Sussex in Neuroscience, and a masters degree at Nottingham University. From there he took on a Research Assistant post at UCL Institute of Ophthalmology before starting his PhD here at the CSCRM.
Episode 53 - Dr Naomi Moris
This stem cells at lunch digested episode sees CSCRM PhD student Steph Hynes interview Dr Naomi Moris about her work studying embryo development using embryonic stem cells and the magical process of how cells make decisions! Dr Moris studied Biological Science as an undergraduate, and found herself particularly interested in developmental biology and epigenetics. After some time spent researching at Cancer Research UK London, she to Cambridge to do a PhD between the departments of Genetics and Haematology. She is currently a Postdoctoral Research Associate in the Department of Genetics, with Alfonso Martinez-Arias’ group. For more information about her research click this link: http://www.newn.cam.ac.uk/person/dr-naomi-moris/
Episode 52 - Dr Katelyn Spillane
Episode 52 - Dr Katelyn Spillane by StemCells@Lunch Digested
Episode 51 - Dr Agathe Chaine
This week’s podcast episode, Dr Ines Sequeira interviews Dr Agathe Chaine from the MRC Laboratory for Molecular Cell Biology based at UCL. We hear about her research history, working with “soft cells”, asymmetric division during the development of embryos, and the different types of techniques are being used in her lab… Dr Chaine was awarded her PhD from the CIRB Collége de France where she stayed on to do a Post Doctoral position researching the biophysical properties of embryonic mitosis. She is now a Post-Doctoral Fellow at the MRC Laboratory for Molecular and Cell Biology based at UCL, where she is studying how cells control their shape and size in asymmetric division during embryonic development For more information about her research please click the following link: http://www.ucl.ac.uk/lmcb/users/agathe-chaigne
Episode 50 - Dr Miguel Bernabe - Rubio
Today’s episode, CSCRM PhD student Daria Belokhvostova interviews EMBO Post Doctoral Fellow Dr Miguel Bernabe Rubio about his research background, what cilium are and why they are important in cell functions like cell division and how cells make decisions... Dr Rubio is an EMBO Post Doctoral fellow. He was awarded his PhD from the Universidad Autonoma in Madrid, Spain. His research focuses on the molecular mechanisms of dedifferentiation in epidermal cells. For more information about him see the below link: http://www.wattlab.org/miguel-bernabé-rubio.html
Episode 49 - Dr Viji Draviam
This week Dr Viji Draviam talks to us about why she studies cell division, what chromosomal stability is, why is it so important to understand this and some tips for starting your own lab! Following a PhD from Trinity College, University of Cambridge (with Prof. Pines, Gurdon Institute, Cambridge, UK, 1998-2001), and Post-doctoral research at the Massachusetts Institute of Technology and Harvard Medical School (with Prof. Sorger, Cambridge, USA; 2002-07), Viji started her own research group as a Cancer Research UK Career Development Fellow at the Department of Genetics, University of Cambridge (2008-15). Viji’s group moved to the School of Biological and Chemical Sciences, QMUL in August 2015. Her research group uses a combination of high-resolution microscopy and molecular biology techniques to understand the molecular mechanisms that ensure chromosomal and genomic stability in normal and cancerous human cells. For more information about her research follow the link: http://www.sbcs.qmul.ac.uk/staff/vijidraviam.html
Episode 48 - Dr Kai Kretzschmar
Welcome back to Stem Cells @ Lunch Digested! This week PhD student Emily Read interviews Dr Kai Kretzschmar about his career path, current research projects, what genetic lineage tracing is, and why he loves doing science! Dr Kretzschmar is a Post-Doctoral Fellow at the Hubrecht Institute in the Netherlands. His work focuses on understanding the gut microenvironment which may influence bowel cancer, and locating the presence of stem cells in the heart. For more information about his work follow this link: http://kaikretzschmar.strikingly.com
Episode 47 - Dr Michela Mazzon
This week, Dr Davide Danovi interviews Dr Michela Mazzon from the Medical Research Council Laboratory for Molecular Cell Biology about her work developing antiviral drugs, what inspired her to start working with viruses, and her hopes for her research.... Click here for more information about her work: http://www.ucl.ac.uk/lmcb/users/michela-mazzon
Episode 46 - Wellcome Trust PhD Cohort Review Writing
Today’s episode of stem cells at lunch we are joined by 5 out of the 6 students of the Wellcome Trust PhD 2016 cohort based here at the CSCRM. They discuss their experience of co-writing a review for the International Journal of Developmental Biology looking at the latest developments in skin research. Hear about the review itself, and the highlights and challenges of the process… Read the review for yourself here: http://www.ijdb.ehu.es/web/paper/170341fw/homeostasis-regeneration-and-tumour-formation-in-the-mammalian-epidermis For more information about the Wellcome Trust PhD Programme click the link: https://www.kcl.ac.uk/lsm/research/divisions/gmm/departments/stemcells/wellcome-trust-phd/wellcome-trust-4-year-phd-programme.aspx
Episode 45 - Sarah Guerra
This week, the Director of Diversity and Inclusion at King's College London, Sarah Guerra, joins us to talk about her career path, what diversity and inclusion is and why it's so important, and what kind of strategies her and her team implementing to encourage change at King's. For more information about the work that Sarah and her team do, follow this link: https://www.kcl.ac.uk/hr/diversity/news%20&%20events/team.aspx
Episode 44 - Dr Jennifer Rohn
Joining us for today's episode is Dr Jennifer Rohn, Principle Investigator at the Centre for Nephrology in the division of Medicine at UCL. She tells us about, her very interesting and varied career path, her current quest in unnderstanding how the bacteria interact with host cells in urinary tract infections, novel antibiotic delivery methods and moral challenges within healthcare…. Dr Rohn runs a research group studying the subversive behaviour of the bacteria involved in chronic urinary tract infection. She also teaches undergraduates, is a novelist and spends her free time doing public engagement and science communication work. For more info about her and her work, please follow the link: http://www.ucl.ac.uk/news/staff/staff-news/0416/21042016-spotlight-on-jennfier-rohn
Episode 43 - Professor Cleo Bishop
Today's episode features Professor Cleo Bishop from The Blizzard Institute at Queen Mary University University of London. She talks to us about her career path, why it is important to learn about how cells age, and how outcomes from her high throughput facility will affect the public… Cleo is a Senior Lecturer and Director for Graduate Studies at the Blizard Institute at Queen Mary University of London. Her research focuses are senescence, aging and cancer. She has also established a high-throughput screening facility at the Institute. For more information about her work please follow this link: https://www.qmul.ac.uk/blizard/staff/centre-for-cell-biology-and-cutaneous-research/items/cleo-bishop.html
Episode 42 - Professor Paola Scaffidi
In this week's episode Professor Paola Scaffidi from the Francis Crick Institute talks to us about how epigenetic factors influence cancer stem cells in cancer development, what cancer stem cells are, and what gets her up in the morning! Professor Scaffidi is an established Group Leader at the Francis Crick Institute since 2015. Her group use genome-wide mapping approaches and state-of-the-art cell biological methods in combination with advanced light microscopy techniques and in vivo approaches to characterise functionally important epigenetic traits of Cancer Stem Cells, with the ultimate goal of identifying novel therapeutic targets. For more information follow the link: https://www.crick.ac.uk/research/a-z-researchers/researchers-p-s/paola-scaffidi/
Episode 41 - Professor Nasir Rajpoot
Today's Stem Cells @ Lunch Digested podcast episode features Professor Nasir Rajpoot from Warwick University. He talks about what computational pathology is, how it can be used for cancer diagnosis and his collaborative project with the Alan Turing Institute. Nasir Rajpoot is Professor in Computational Pathology at the Department of Computer Science, University of Warwick. His research interests include Computational Pathology, Image Analytics, Applied Machine Learning, Cancer Biomarkers. Click the link for more information about him and his work: https://warwick.ac.uk/fac/sci/dcs/people/nasir_rajpoot/
Episode 40 - Dr Caroline Hill
In this week's stem cells @ lunch digested episode, PhD student Ana-Maria Cujba speaks to Dr Caroline Hill from the Francis Crick Institute about her research into cell signalling and using fish as models to study signalling during embryonic development. Dr Caroline Hill is an established Group Leader at the Francis Crick Institute. She was awarded her PhD from Cambridge University, was elected to EMBO in 2002 and to the Academia Europaea in 2013. In 2015, she was elected a Fellow of the European Academy of Cancer Sciences. For more information about her work please follow the link... https://www.crick.ac.uk/research/a-z-researchers/researchers-d-j/caroline-hill/
Episode 39 - Dr Megha Prakash Bangalore
In this episode we interview Dr Megha Prakash Bangalore about her work on lipid metabolism in stem cells... Megha obtained her PhD in Developmental Biology and Embryology from Manipal University in Bangalore and is now a Research Associate at Imperial College London. For more info follow the link: www.linkedin.com/in/megha-prakash…galore-64723016/
Episode 38 - Dr Robert Hynds
In today's episode we are joined by Dr Rob Hynds. He talks about his background of studying human lung cancers, the challenges of developing therapies, working in a multidisciplinary setting and training for the Belfast Marathon! Rob completed his PhD in epithelial stem cell biology in the Lungs For Living Research Centre in 2016 and is now a Sir Henry Wellcome Postdoctoral Fellow working on Prof. Charles Swanton's lung TRACERx clinical study in collaboration with Dr. Sergio Quezada's group. Rob's work aims to develop patient-derived cancer models and develop immune-based therapies for lung cancer. For more information about Dr Hynds please see https://iris.ucl.ac.uk/iris/browse/profile?upi=HYNDS02
Episode 37 - Dr Shukry Habib
In this episode of Stem Cells at Lunch Digested we hear from Dr Shukry Habib about his research focuses at the Centre for Stem Cells and Regenerative Medicine and how he came to work here. Shukry Habib pursued his undergraduate and Master degrees in Israel at the Technion and Tel-Aviv university, respectively. He obtained his Dr.rer. nat from Ludwig Maximilian University (LMU) of Munich, Germany and carried out postdoctoral research at Stanford University, California, USA. He is currently a Senior Research Fellow at the Centre for Stem Cells and Regenerative Medicine and was recently awarded a Sir Henry Dale fellowship (Wellcome Trust and Royal Society, UK). For more information about Dr Habib and his work please see www.kcl.ac.uk/lsm/research/divis…hukry-j-habib.aspx
Episode 36 - Dr Andrea Serio
In this episode of StemCells@Lunch digested Dr Andrea Serio talks about how he and his team use bioengineering to understand neurodegeneration. Dr Serio was appointed a lectureship at King's College London in September 2017, and joined the division of Tissue Engineering and Biophotonics, where he has now established an independent group focused on neural circuit engineering (NCE). For more information please see the Serio lab website: www.seriolab.com
Episode 35 - Bishop Lee Rayfield
Dr Lee Rayfield was educated at the University of Southampton, where he gained a Bachelor of Science (BSc) honours degree in Biology in 1978. He then studied for his Doctor of Philosophy (PhD) degree from St Mary's Hospital Medical School (Paddington, Greater London), being awarded his doctorate in 1981, after which he remained as a post-doctoral researcher until 1984. His final medical post was as a lecturer in immunology at UMDS. In 1991 he began studying for the ministry, and became the Bishop of Swindon, the sole suffragan bishop of the Diocese of Bristol, in 2005.
Episode 34 - Dr Robert Knight
Dr Robert Knight studied for a PhD in Molecular Evolution at the University of Reading before changing directions and pursuing postdoctoral research in the field of musculoskeletal development at the University of California, Irvine and the University of Sheffield. He moved to King’s College London as a BBSRC David Phillips Fellow in 2007 and his group is focused on the signals that direct the complex behaviour of progenitor cells during development of the vertebrate head. His current focus is to determine how progenitor cells are controlled during tissue regeneration and identify the factors that control them, using in vivo imaging and genetic manipulations. For more info please see ... https://www.kcl.ac.uk/dentistry/research/divisions/craniofac/ResearchGroups/KnightLab/GroupMembers.aspx
Episode 33 - Dr Mathis Riehle
Dr Mathis Riehle is a Senior Researcher at the Glasgow University Centre for Cell Engineering investigating the molecular mechanisms of how cells interact with surfaces using devices made by micro- and nanofabrication with a specific chemical, topographic or mechanical surface design. For more information about his work please follow the link... https://www.uofgcce.org/staff
Episode 32 - Dr Stephen Patrick
Dr Stephen Patrick is a cell biologist with a focus on molecular imaging. He completed his B.Sc. in Cell Biology at the University of Durham in 2009 and completed his PhD at the University of Cambridge in 2013, working on the development of novel genetic reporters for MRI, SPECT, and Bioluminescence imaging. Stephen is now a research associate at the Centre for Advanced Biomedical Imaging (CABI) at UCL, working on developing in vivo cell tracking techniques for use in stem cells. If you would like to know more visit his webpage https://www.ukrmp.org.uk/hubs/safety/our-research-team/dr-stephen-patrick-university-college-london/
Episode 31 - Dr Ophir Klein
The Klein lab is interested in understanding how organs form in the embryo and how they renew and regenerate in the adult. Their research is centered on understanding how development and regeneration normally occur in the hope of one day treating diseases that result from abnormalities in these processes. If you want to find out more about Ophir and the lab please follow the link to http://klein.ucsf.edu/welcome-klein-lab Speak to you next week!
Episode 30 - Dr Helena Kilpinen
Helena is interested in the functional effects of genetic variation in human induced pluripotent stem cells (iPSC). Her research combines computational and experimental methods in iPSC-based models to understand the cellular mechanisms that lead to rare human diseases. Helena is a human geneticist who leads a research group at the UCL Great Ormond Street Institute of Child Health. She is a MRC eMedLab career development fellow (www.emedlab.ac.uk) and holds an appointment also at the Wellcome Trust Sanger Institute. Helena received her PhD from the University of Helsinki, where she studied the genetic mechanisms underlying autism spectrum disorders. She then transitioned to functional genomics, using diverse next-generation sequencing -based assays to study how DNA sequence variation influences different levels of gene regulation in human cells, first at the University of Geneva, and then at the EMBL-EBI. She joined the Human Induced Pluripotent Stem Cells Initiative (www.hipsci.org) in 2014 and has since focused on the functional characterization of genetic variation in human iPS cells from hundreds of donors. The long-term goal of her research is to combine high-dimensional molecular data from iPSCs and iPSC-derived cell types with clinical data to comprehensively model the cellular mechanisms that lead to rare human diseases.
Episode 29 - Dr Rosalind Hannen
Dr Rosalind Hannen, our today's interviewee at Stem Cells @lunch digested, is a postdoctoral researcher at the Blizard Institute in Queen Mary University of London. For any questions email us at stemcellsatlunch@kcl.ac.uk
Episode 28 - Dr Yan Yan Shery Huang
Dr Shery Huang's group 'Biointerface', is driven by translational bioengineering research, focusing on 3D bioprinting/ biomicrofabrication, and developing biomimetic organ-on-chips for high throughput drug testing. If you would like to know more visit her webpage:http://www.eng.cam.ac.uk/profiles/yysh2 Happy New Year from all of us at Stem Cells @lunch digested! If you have any questions just email: stemcellsatlunch@kcl.ac.uk
Episode 27 - Dr Thea Stewart
In this episode of Stem Cells @lunch digested we interviewed Thea Stewart, a research Fellow in Metals Analysis and Bioimaging at King's College London. Thea is not only a great scientist but also a talented musician and we have a unique live performance ready for you, our listener, as an early Christmas gift! :)
Episode 26 - Dr Ravi Desai
This week on Stem Cells at Lunch we interviewed Dr Ravi Desai, the scientist behind the Making Lab at The Francis Crick Institute: https://www.crick.ac.uk/research/science-technology-platforms/making-lab/ If you have question or comments, drop as a line on stemcellsatlunch@kcl.ac.uk
Episode 25 - Gemma Milne
"In our world of co-creation, hyper-connectivity and exponentially growing technology, our science industry is in much need of disruption. Our slow processes, our steep barriers to entry, and our poor external and internal communication is eroding trust and discouraging talent. We speak to the innovators, iconoclasts and entrepreneurs intent on creating change in science. We record podcasts, we write editorials, we run events. This is Science: Disrupt." Have a look at https://sciencedisrupt.com and share your thoughts with us using stemcellsatlunch@kcl.ac.uk
Episode 24 -Oliver Baker
In today's episode we interviewed Dr Oliver Baker, the Head of Gene Editing & Embryology Core (GEEC) at King’s College London . In this facility at King’s, he is using crisp technology for gene editing. If you have any comments or questions email us on stemcellsatlunch@kcl.ac.uk
Episode 23 - Dr Jonathan Chubb
Dr Jonathan Chubb - http://www.ucl.ac.uk/lmcb/users/jonathan-chubb
Episode 22 - Dr. Francesco Iorio
Francesco Iorio is a senior bioinformatician working with Open Targets: a public-private initiative involving teams at the Wellcome Trust Sanger Institute, the EMBL – European Bioinformatics Institute, GlaxoSmithKline and Biogen, with the mission of exploiting Big Data for systematically identifying new therapeutic targets. Previously he was an ESPOD fellow in joint post-doctoral program between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute under the guidance of Julio Saez-Rodriguez and Mathew Garnett. If you have any comments or questions email us on stemcellsatlunch@kcl.ac.uk
Episode 21 - Dr. Dinis Calado
Stem Cells @ Lunch is digested back! In today's episode we interviewed Dr Dinis Calado, a group leader in the Francis Crick Institute. His research aims to elucidate mechanisms by which healthy cells of the haematopoietic system become cancerous, with major focus on B lymphocytes. If you have any comments or questions email us on stemcellsatlunch@kcl.ac.uk
Episode 20 - Dr Nathan Benaich
Dr Nathan Benaich is an investor, a technologist and a former scientist. He has done his PhD at the CSCRM and now works with companies that solve challenging and valuable problems using breakthrough technologies including, but not limited to, artificial intelligence.
Episode 19 - Jim Bending
http://cambridge-stem-cell-institute.appstor.io
Episode 18 - Chris Baker
Episode 18 - Chris Baker by StemCells@Lunch Digested
Episode 17 - Dr Edouard Hanezzo
Dr Edouard Hanezzo is a postdoctoral researcher with Prof Ben Simons at The University of Cambridge. Their research applies methods of non-equilibrium statistical mechanics and population dynamics to lineage tracing studies to investigate mechanisms of stem cell fate in development and maintenance. If you like this episode leave us a review on iTunes and email us on stemcellsatlunch@kcl.ac.uk
Episode 16 - Dr Mathieu Bolen
Dr Mathieu Bollen is a Group leader in the Laboratory of Biosignaling & Therapeutics and Chair of Department of Cellular and Molecular Medicine at the University of Leuven, Belgium. In his lab they investigate cellular signal transduction pathways at the molecular level, with the major goal of identifying and developing novel biomarkers or therapeutic targets for human diseases.
Episode 15 - Researching Abroad
Researching abroad: The Center for Stem Cell and Regenerative Medicine is a very multicultural group. In this episode we will have the opportunity to listen some of the scientists working in the Center who have come from abroad to further their research careers. They will be talking about their experience of working in research in the UK and how they see the landscape in the future. Scientist invited: Victor Negri (Brazil), Stephanie Telerman (France), Matteo Vietri (Italy), Gernot Walko (Austria), Inês Sequeira (Portugal) and Rocio Sancho (Spain).
Episode 14 - Mr Hugh Wright
Hugh Wright is a trainee Plastic Surgeon, currently studying for the degree of Doctor of Philosophy (DPhil) in Oncology at the University of Oxford. His project- "Investigation of the molecular effects of cooling human burns"- aims to investigate how cooling of a burn reduces the burn's severity and improves outcome for the patient. At present, there is no complete explanation as to the beneficial mechanism of cooling, and understanding this process would yield huge potential benefit for many of the 250,000 people who sustain burns each year in the UK alone, and to the far greater number of burns victims in the Developing World.
Episode 13 - Dr Joana Neves
In today's episode we interviewed Dr Joana Neves, a Marie Sklodowska-Curie Fellow at King's College London. If you have any comments or questions email us on stemcellsatlunch@kcl.ac.uk
Episode 12 - Clustermarket
Cluster market.com gives scientists the opportunity to access latest technology in an easy and affordable way by providing an online sharing platform.
Episode 11 - Miss Lucia Salz
On this week episode we're joined by Lucia Salz, an erasmus student here at the Centre for Stem Cells and Regenerative Medicine. As usual, if you have any questions just drop as an e-mail on stemcellsatlunch@kcl.ac.uk Talk to you next week!
Episode 10 - Ole Press and Oliver Keminer
Episode 10 - Ole Press and Oliver Keminer by StemCells@Lunch Digested
Episode 9 - Mr David Martin
David is an architect who has led the design for many of our award-winning healthcare, research, and education projects in the United Kingdom and the United States. He’s particularly interested in design which creates a memorable sense of place while promoting a sense of clarity, optimism, and engagement. He believes the built environment can and should enrich peoples’ lives. You can find out more about their work at http://www.stantec.com/about-us/people/m/martin-david.html If you have any comments or questions just email us: stemcellsatlunch@kcl.ac.uk
Episode 8 - Science Week With Judith Kerr Primary School
Last week, as part of British Science Week 2017, ten young scientists from Judith Kerr Primary School in London visited our Centre. It was a fascinating morning for the children that had the opportunity to observe the Watt Lab scientists at work. As part of their activities, they acted as pathologists, identifying healthy and unhealthy cells under a microscope, and extracted the DNA from a strawberry. At the end of their visit, the children took part in a podcast, where they had the opportunity to ask some of the scientists about their work. It was a truly extraordinary day and a wonderful opportunity to inspire young scientists of the future. If you would like your school to be next email us to stemcellsatlunch@kcl.ac.uk
Episode 7 - Prof Manuel Salmeron-Sanchez
For today's episode we interviewed Professor Manuel Salmeron-Sanchez, the Head of the Division of Biomedical Engineering and Chair of Biomedical Engineering in the School of Engineering at the University of Glasgow (http://www.gla.ac.uk/schools/engineering/staff/manuelsalmeron-sanchez/#/). Don't forget to send us your comments and questions to stemcellsatlunch@kcl.ac.uk
Episode 6 - Dr James Briscoe
On today's episode we have Dr. James Briscoe, a principal investigator at the Francis Crick Institute. You can find out more about the Briscoe's lab here: https://crick.ac.uk/james-briscoe and if you have any questions for us just email stemcellsatlunch@kcl.ac.uk
Episode 5 - Dr Tuzer Kalkan
On today's episode we are joined by Dr Tuzer Kalkan, a postdoctoral researcher at the Cambridge Stem Cell Institute!
Episode 4 - Dr Su Lwin
On this week episode of Stem Cells at Lunch digested we have with us Dr Su Lwin, who is a trained medical doctor currently doing her PhD here at King's College London!
Episode 3 - Mr Charles Fracchia
Charles Fracchia is the founder and CEO of BioBright, a company building the smart lab to improve reproducibility in bio-medical research. He is interested in how artificial intelligence, automation and human-computer interfaces can improve the human ability to do research. He completed his bachelors in biology at Imperial College, his masters between the MIT Media Lab and Harvard Medical School. In 2016, Charles was named one of 35 innovators under 35 by the MIT Technology Review. He is the recipient of several awards including IBM PhD fellowships, an Extraordinary Minds fellowship, one of the first Awesome Foundation fellowships and an Amplify Partners fellowship. He is the author of several patents and is actively authoring more in the field of future laboratory tools. Charles has also been involved in obtaining numerous grants and contracts from DARPA, NSF, Google X, Knight Foundation and the Shanghai High Tech Incubator totaling several millions since 2012.
Episode 2 - Dr Sara Jane Dunn
To celebrate the International Day of women and girls in science , in this week’s podcast we have Dr Sara-Jane Dunn. Sara is a scientist based within the Biological Computation group at Microsoft Research Cambridge, and an affiliate researcher at the Wellcome Trust – Medical Research Council Stem Cell Institute, University of Cambridge. She trained as a mathematician and got a PhD in Computer Science from the University of Oxford. Currently Sara-Jane works at the interface between mathematics, computer science and biology, specifically developing a theory of biology as computation, in which the biochemistry of the cell performs information processing in the service of decision-making. To fulfil her goal she collaborates with research experimentalists at the Universities of Cambridge and Padova to investigate stem cell decision-making throughout Development. The goal of her research is ultimately to make cells programmable, which could fundamentally transform medicine, agriculture and even the ways we generate energy.
Episode 1 - Professor Ian Mackenzie
Today at Stem Cells @Lunch Digested we have Prof Ian MacKenzie. Ian is Professor of Stem Cell Science at the Blizzard Institute, part of Queen Mary University of London. His research interests are the cellular mechanisms involved in the maintenance of skin and oral mucosa; stem cells; tissue renewal; and cancer.
Episode 0 - Intro
Welcome to Stem Cells @Lunch digested! This new podcast series will bring you weekly the breath of research that is happening at the Centre for Stem Cells and Regenerative Medicine! If you have your questions or if you want to send us your comments just reach out to stemcellsatlunch@kcl.ac.uk