Can Creatine Reduce Depression?

Episode 48 of the Talking With Docs Podcast podcast, hosted by Dr. Brad Weening and Dr. Paul Zalzal, titled "Can Creatine Reduce Depression?" was published on August 3, 2025 and runs 6 minutes.

August 3, 2025 ·6m · Talking With Docs Podcast

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Episode Description

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Is Creatine Just for Muscles? New Study Says No

Creatine is known for building strength — but new research shows it may also reduce symptoms of depression.

In this episode, doctors break down a study where creatine, combined with CBT (cognitive-behavioural therapy), helped improve mental health. It’s safe, accessible, and now showing promise beyond physical performance.

We cover:

How creatine affects brain function
What a recent clinical trial revealed
Whether creatine could support mood and therapy
Who might benefit and if it's safe to try

If you take creatine or are curious about mental health supplements, this is for you.

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📄 Study Reference: Sherpa NN, et al. Creatine + CBT in depression. Eur Neuropsychopharmacol. 2025;90:28–35. https://doi.org/10.1016/j.euroneuro.2024.10.004

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