Science happens, and so do mistakes

EPISODE · Apr 1, 2026 · 14 MIN

Science happens, and so do mistakes

from Absolute Gene-ius · host Raquel Munoz, Lisa Crawford, Patrick Hanington, Lydia Hayes Guastella, Jordan Ruggieri, Brian Bahder, MinGin Kim, Brandi Kiel Reese, Pavla Brachova

Science doesn’t just advance through breakthroughs, it advances through mistakes. This Science Snapshot episode embraces a universal truth of research: if you haven’t messed something up in the lab, you probably haven’t been there very long. From chemical reactions gone wrong to experiments derailed by one small oversight, these stories are as relatable as they are unforgettable. In this curated “best of” revisit, Absolute Gene-ius brings together candid lab-fail moments shared by past guests across multiple seasons. You’ll hear stories involving exothermic sodium hydroxide reactions, PCR screening disasters caused by a simple reagent mix-up, forgotten spike-ins during RNA-seq prep, accidental sequencing of human DNA instead of plant viruses, and even being locked inside a cold room on the first week in a new lab. Along the way, the episode highlights the science behind each mistake and the importance of lab safety while reinforcing an important message for scientists at every stage: failure is part of the process, and every mistake becomes a lesson worth remembering. Visit the Absolute Gene-ius page to learn more about the guests, the hosts, and the science we explore. Discover the Applied Biosystems QuantStudio Digital and Real-Time PCR Systems powering real-world research across neuroscience, oncology, agriculture, and more.

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Science happens, and so do mistakes

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