Anoncast

Eli Lilly is one of the oldest and most important companies in modern medicine, but its current moment feels less like a standard pharma story and more like a strategic hinge point. In this parody Acquired-style episode, Ken and Ava trace Lilly from Colonel Eli Lilly's anti-elixir manufacturing ethos, through insulin and Humulin, into the blockbuster era, incretins, GLP-1s, and the obesity supercycle. The episode asks a simple question: is Lilly riding an extraordinary product wave, or is it building a deeper metabolic-health platform with durable strategic power? Presenting sponsors: TrainTrackr NYC Subway LED Map: https://www.traintrackr.io/product/mta2 Dad Brand Apparel: https://dadbrand.com/ Carve-outs: Frieren: Beyond Journey's End: https://www.viz.com/frieren-beyond-journeys-end Confessions of a Mask by Yukio Mishima: https://www.ndbooks.com/book/confessions-of-a-mask/ MoMA PS1: https://www.momaps1.org/ Queens waterfront / Hunter's Point South Park: https://www2.nycgovparks.org/parks/hunters-point-south-park Fauxcquired is a parody project by Neel Baronia. It is not affiliated with Acquired or acquired.fm, but that is also a great podcast, which you can check out here: https://www.acquired.fm/

Original blog: https://bulletin.hds.harvard.edu/suprahuman-but-inhuman-gods/ One immediately troubling concern is that some of the aspects of these interactions that seem appropriate while engaging machines might extend to other conversational contexts. Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

Original blog: https://paulgraham.com/brandage.html In the early 1970s disaster struck the Swiss watch industry. Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

Original blog: https://www.anthropic.com/constitution Claude and the mission of Anthropic Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

Original blog: https://www.darioamodei.com/essay/the-adolescence-of-technology The Adolescence of Technology Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

Original blog: https://www.nbaronia.com/AGI-Has-Already-Happened-d8461755872840cabddac321f52b1e89 AGI Has Already Happened Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

Original blog: https://www.paulgraham.com/alien.html October 2022 If there were intelligent beings elsewhere in the universe, they'd share certain truths in common with us. Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

Original blog: https://grugbrain.dev/ this collection of thoughts on software development gathered by grug brain developer Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

Original blog: https://www.paulgraham.com/progbot.html (This essay is from the introduction to On Lisp.) It's a long-standing principle of programming style that the functional elements of a program should not be too large. If some component of a program grows beyond the stage where it's readily comprehensible, it becomes a mass of complexity which conceals errors as easily as a big city conceals fugitives. Such software will be hard to read, hard to test, and hard to debug.In accordance with this principle, a large program must be divided into pieces, and the larger the program, the more it must be divided. How do you divide a program? The traditional approach is called top-down design: you say "the purpose of the program is to do these seven things, so I divide it into seven major subroutines. The first subroutine has to do these four things, so it in turn will have four of its own subroutines," and so on. This process continues until the whole program has the right level of granularity-- each part large enough to do something substantial, but small enough to be understood as a single unit.Experienced Lisp programmers divide up their programs differently. As well as top-down design, they follow a principle which could be called bottom-up design-- changing the language to suit the problem. In Lisp, you don't just write your program down toward the language, you also build the language up toward your program. As you're writing a program you may think "I wish Lisp had such-and-such an operator." So you go and write it. Afterward you realize that using the new operator would simplify the design of another part of the program, and so on. Language and program evolve together. Like the border between two warring states, the boundary between language and program is drawn and redrawn, until eventually it comes to rest along the mountains and rivers, the natural frontiers of your problem. In the end your program will look as if the language had been designed for it. And when language and program fit one another well, you end up with code which is clear, small, and efficient. It's worth emphasizing that bottom-up design doesn't mean just writing the same program in a different order. When you work bottom-up, you usually end up with a different program. Instead of a single, monolithic program, you will get a larger language with more abstract operators, and a smaller program written in it. Instead of a lintel, you'll get an arch. In typical code, once you abstract out the parts which are merely bookkeeping, what's left is much shorter; the higher you build up the language, the less distance you will have to travel from the top down to it. This brings several advantages: Convert your blog to audio at https://www.anoncast.net/ , or browse generated episodes at https://www.anoncast.net/generated

November 2016 If you're a California voter, there is an important proposition on your ballot this year: Proposition 62, which bans the death penalty. Original blog: https://www.paulgraham.com/prop62.html Made with Anoncast: https://www.anoncast.net

Due to this month’s winner featuring political violence as a key component, there is no free preview. Original blog: https://shortstory.substack.com/p/charlotte-of-caen Made with Anoncast: https://www.anoncast.net

This story is meant to be listened to. Original blog: https://davidbieber.com/post/2022-12-30-go-note-go-story/ Made with Anoncast: https://www.anoncast.net