Compass Opioid Stewardship Coaches Top 5 Podcast

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing benefits of primary care driven MOUD, perioperative recommendations for buprenorphine continuation, and more!  Differences in buprenorphine initiation and retention for opioid use disorder between primary care and substance use disorder specialty care settings, Published in the Journal of Substance Use and Addiction Treatment, April 2026  Clinical pain management: Current practice and recent innovations in research, Published in Cell Reports Medicine, October 2024  Perioperative Management of Patients on Buprenorphine, Published in Current Pain and Headache Reports, February 2026  Electronic Intervention for Patient-Managed Benzodiazepine TaperingA Randomized Clinical Trial, Published in JAMA Network Open, January 2026  Long-term use of prescription opioids for non-cancer pain and mortality: a population-based, propensity-weighted cohort study, Published in Public Health, July 2024 

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing public views on people with OUD, psychedelic retreats, expanding access to medications for AUD, and more!  Public Views About Opioid Overdose and People With Opioid Use Disorder, Published in JAMA Network Open, January 2026  Comparative Effectiveness of Opioid Tapering or Abrupt Discontinuation vs Stable Opioid Therapy, Published in JAMA Network Open, August 2022  Pain Management in the Older Adult with Opioid Use Disorder,Published in Clinics in Geriatric Medicine, September 2025  Reported Safety Practices of Publicly Advertised Psychedelic Retreats, Published in JAMA Network Open, January 2026  Structural Approaches to Expand Access to Medication Treatment for Alcohol Use Disorder, Published in JAMA Network Open, January 2026 

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing mindfulness based interventions, the role of peer navigators, US overdose deaths, and more!  Mindfulness-Based Interventions for Adolescent Substance Use and Substance Use Disorders: A Systematic Review, Published in Pediatrics, February 2026  Prescribing and deprescribing guidance for benzodiazepine and benzodiazepine receptor agonist drugs: a systematic review of clinical practice guidelines, Published in eClinical Medicine, April 2024  A Pharmacist's Guide to Managing Difficult Conversations in Pain Management and Opioid Use Settings, Published in the Journal of Pain and Palliative Care Medicine, December 2025  The Role of Peer Navigators After Nonfatal Opioid Overdose—Context, Evidence, and Future Directions, Published in JAMA Network Open, February 202  As US Overdose Deaths Drop, Researchers Search for Explanations, Published in JAMA Network Open, January 2026 

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing spinal manipulation, central sensitization, yoga for opioid withdrawal, and more!  Spinal Manipulation and Clinician-Supported Biopsychosocial Self-Management for Acute Back Pain: The PACBACK Randomized Clinical Trial, Published in JAMA, December 2025  Opportunities for chronic pain self-management: core psychological principles and neurobiological underpinnings, Published in the Lancet, May 2025  Social chronic pain: the affective response to social exclusion, Published in Journal of Headache and Pain, December 2025  Yoga for Opioid Withdrawal and Autonomic Regulation: A Randomized Clinical Trial, Published in JAMA Psychiatry, January 2026  Prevalence of Central Sensitization in Postural Tachycardia Syndrome, Published in JAMA Network Open, January 2026   

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing harms of chronic marijuana smoking, levaraging the 72 hour rule for methadone, and more!  Parental opioid prescriptions and the risk of opioid use in adolescents and young adults: The HUNT Study linked with prescription registry data, Published in PLOS Medicine, October 2025  Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use, Published in JAMA Cardiology, May 2025  Incidence and Risk Factors of Chronic Pain After Critical Care Illness: A Systematic Review and Meta-­ Analysis, Published in Nursing in Clinical Care, January 2026  Leveraging the 72-Hour Rule Change to Support Transition From Hospital to Opioid Treatment Program, Published in JAMA Network Open, November 2025  Population-Level Health Benefits and Harms Associated With Buprenorphine/Naloxone vs Methadone, Published in JAMA Network Open, December 2025 

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing buprenorphine for pain, harm reduction for benzodiazepine use, and more!  Buprenorphine for the Management of Chronic Pain: National Guidance Document, Published by the VA Pharmacy Benefits Management Services and the National Formulary Committee in Collaboration with the VHA National Office of Pain Management, Opioid Safety and PDMP (PMOP), March 2024  Harm reduction approaches for the use of benzodiazepines: a scoping review, Published in Springer Nature Link, October 2025  Definitive urine drug test findings in patients prescribed opioids for pain from a large national database, Published in the Journal of Opioid Management, July-August 2022  Duration of Methadone and Buprenorphine-Naloxone Treatment, Published in JAMA Network Open, July 2025  Safe and Sufficient—Ibuprofen for Pediatric Musculoskeletal Injuries, Published in JAMA, January 2026 

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the potential role of GLP-1 therapies in alcohol and substance use disorders, risk factors associated with long-term opioid prescribing, patient motivation and readiness to taper opioids for chronic pain, national trends in ADHD medication prescribing, and more! GLP-1 Therapeutics and Their Emerging Role in Alcohol and Substance Use Disorders: An Endocrinology Primer Published in the Journal of Endocrine Society, October 2025 A national cohort study of long-term opioid prescription and sociodemographic and health care-related risk factors Published in Communications Medicine, September 2025 Patient Motivation to Reduce or Discontinue Opioids for Chronic Pain: Self-efficacy, Barriers, and Readiness to Change Published in the Clinical Journal of Pain, January 2024 Population-Level Trends in Attention-Deficit/Hyperactivity Disorder Medication Prescribing Published in JAMA Network Open, December 2025 Increased Avoidance Learning in Chronic Opioid Users Published in JAMA Pyschiatry, November 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the relationship between medical cannabis and opioid receipt in chronic pain, clinical challenges in managing risks of continuing versus tapering long-term opioid therapy, the impact of cannabis use on nicotine vaping cessation outcomes, and more! Medical Cannabis and Opioid Receipt Among Adults With Chronic Pain Published in JAMA Internal Medicine, December 2025 Experiences of long-term benzodiazepine use and addiction amid changes in guidelines for the prescription of narcotic drugs: a qualitative study Published in Springer Nature Link, August 2025 Management of patients at risk of harms from both continuing and discontinuing their long-term opioid therapy: A qualitative study to inform the gap in clinical practice guidelines Published in Pain Practice, January 2025 Digital Cognitive Behavioral Treatment for Generalized Anxiety Disorder A Randomized Clinical Trial Published in JAMA Network Open, December 2025 Cannabis Use and Nicotine Vaping Cessation Outcomes: A Secondary Analysis of a Randomized Clinical Trial Published in JAMA Network Open, December 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing healthcare enrollees and access outcomes, early high-risk opioid prescribing and persistent use among injured workers, the need for oversight of substance use reduction apps, barriers to universal MOUD availability in U.S. jails, and more! Trends in Methadone Use for Pain and Opioid Use Disorder Among Medicaid Enrollees Published in JAMA Health Forum, November 2025 Early High-Risk Opioid Prescribing and Persistent Opioid Use in Australian Workers with Workers' Compensation Claims for Back and Neck Musculoskeletal Disorders or Injuries: A Retrospective Cohort Study Published in Springer Nature Link, March 2025 The Need for Oversight Over Apps for Substance Use Reduction Published in JAMA, October 2025 Barriers to Universal Availability of Medications for Opioid Use Disorder in US Jails Published in JAMA Network Open, April 2025 Transient and Long-Term Risks of Common Physical Activities in People With Low Back Pain Published in JAMA Network Open, December 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing opportunities to reduce medication overuse in urgent care settings, emerging advances in clinical pain management, the role of placebo responses in analgesic trials, evidence for virtual reality as a treatment for chronic low back pain, and more! Antibiotic, Glucocorticoid, and Opioid Prescribing in Urgent Cares: An Opportunity for Reducing Medication Overuse Published in the Annals of Internal Medicine, July 2025 Clinical pain management: Current practice and recent innovations in research Published in Cell Reports Medicine, October 2024 Placebo Responses in Clinical Trials of Analgesics, published in Neurological Clinics Published Neurological Clinics, September 2025 Therapeutic effects of virtual reality technology on chronic low back pain Published in Medicine (Baltimore), November 2025 Smartphone-Based Muscle Relaxation for Migraine in the Emergency Department A Randomized Clinical Trial Published in JAMA Network Open, October 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing trial data on cannabidiol for fibromyalgia, the role of non-opioid psychiatric medications in chronic pain, the complex relationship between low back pain and depression, evidence for intra-articular injections in shoulder arthritis, and more! Cannabidiol versus placebo in patients with fibromyalgia: a randomised, double-blind, placebo-controlled, parallel-group, single-centre trial Published in Annals of Rheumatic Disease, August 2025 Non-opioid psychiatric medications for chronic pain: systematic review and meta-analysis Published in Frontiers, October 2024 The Potential Relationship Between Low Back Pain and Depression: A Comprehensive Review Published in Brain Behavior, November 2025 Intra-articular injections for shoulder arthritis in adults: a systematic review Published in European Journal of Medical Research, November 2025 Recommendations for Addressing In-Hospital Substance Use From a National Delphi Consensus Process Published in JAMA Network Open, August 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing updated analyses of tramadol's effectiveness for chronic pain, advances in non-pharmacological pain interventions, comparative effects of preoperative hypnosis versus mindfulness on postoperative symptoms, and more! Tramadol versus placebo for chronic pain: a systematic review with meta-analysis and trial sequential analysis Published in BMJ Evidence-Based Medicine, October 2025 An update on non-pharmacological interventions for pain relief Published in Cell Reports Medicine, February 2025 Stress, pain intensity, and work productivity in individuals with chronic pain: a cross-sectional observational study Published in BMC Public Health, November 2025 Preoperative Hypnosis versus Mindfulness for Reducing Postoperative Symptoms in Breast Surgery: A Randomized Clinical Trial Published in Anesthesiology, November 2025 Medicaid Coverage Policy Variations for Chronic Pain and Opioid Use Disorder Treatment Published in JAMA Network Open, August 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the HRQ Medications for Opioid Use Disorder Playbook, outcomes of hospital addiction consultation services, comparative effectiveness of interventional procedures for chronic spine pain, postoperative cold therapy to reduce pain and opioid use, and more! Medications for Opioid Use Disorder Playbook Published by HRQ, October 2025 Hospital Addiction Consultation Service and Opioid Use Disorder Treatment The START Randomized Clinical Trial Published in JAMA Internal Medicine, April 2025 Common interventional procedures for chronic non-cancer spine pain: a systematic review and network meta-analysis of randomised trials Published in BMJ, February 2025 The use of cold therapy unit in the postoperative period influences pain and narcotic use following arthroscopic rotator cuff repair Published in the Journal of Shoulder and Elbow Surgery, October 2025 Evaluation of a Novel Patient-Centered Methadone Restart Protocol Published in JAMA Network Open, August 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing approaches that increase MOUD delivery in primary care, comparative effectiveness of extended-release naltrexone versus buprenorphine-naloxone, best-supported interventions for chronic low back pain, the role of patient resilience in perioperative outcomes, and more! Increasing Opioid Use Disorder Medication Treatment in Primary Care—What Works? Published in JAMA Internal Medicine, July 2025 Effectiveness of Injectable Extended-Release Naltrexone vs Daily Buprenorphine-Naloxone for Opioid Dependence: A Randomized Clinical Noninferiority Trial Published in JAMA Psychiatry, December 2017 Pain Management Interventions for the Treatment of Chronic Low Back Pain: A Systematic Review and Meta-Analysis Published the Clinical Journal of Pain, July 2023 The effect of patient resilience on perioperative outcomes: a scoping review Published in British Journal of Anesthesia, October 2025 Opioid Exposure Measurement in Postacute Care Under Medicare Consolidated Payments Published in JAMA Health Forum, September 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing dementia risk following gabapentin use in chronic low back pain, predictors of outcomes during short-term medically supervised opioid withdrawal, nonpharmacologic pain interventions such as auricular acupressure in older adults, and more! Risk of dementia following gabapentin prescription in chronic low back pain patients Published in Regional Anesthesia and Pain Medicine, July 2025 Predictors of outcome for short-term medically supervised opioid withdrawal during a randomized, multicenter trial of buprenorphine-naloxone and clonidine in the NIDA clinical trials network drug and alcohol dependence Published in Drug and Alcohol Dependence, October 2009 Auricular point acupressure for older adults with chronic low back pain: a randomized controlled trial Published in Pain Medicine, September 2025 Implementation opportunities for optimizing retention on buprenorphine treatment for people with opioid use disorder in West Virginia Published in Drug and Alcohol Dependence, November 2025 FDA Requires Stronger Opioid Pain Medication Warning Labels Published in JAMA Network Open, September 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing updated understanding of the harms and uncertain benefits of long-term opioid therapy, the effectiveness of brief patient-facing education tools for low back pain in primary care, and more! Long-Term Opioid Therapy for Pain What Is Known About Harms—and Still Not Known About Benefits Published in JAMA, August 2025 One-Page Patient Fact Sheets for Low Back Pain in Primary Care A Randomized Clinical Trial Published in JAMA Network Open, July 2025 Short-term effects of classical massage added to a conventional physiotherapy on non-specific chronic low back Pain: A randomized, placebo-controlled study Published in the Journal of Bodywork and Movement Therapy, October 2025 Discrepancies in opioid prescription and comorbidity burden in chronic low back pain: The impact of race, ethnicity, and socioeconomic status Published in the Journal of Opioid Management, May-June 2025 Parental Diseases of Despair and Suicidal Events in Their Children Published in JAMA Network Open, September 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing how physical activity influences the relationship between weight and pain-related disability, the impact of CYP2D6 phenotypes on emergency department visits among patients treated with opioids, updated evidence on tramadol's benefits and harms, and more! Physical activity mediates the relationship between weight status and pain impacting daily activities Published in Epidemiology and Population Health, July 2025 CYP2D6 Phenotypes and Emergency Department Visits Among Patients Receiving Opioid Treatment Published in JAMA Network Open, July 2025 Tramadol (with or without acetaminophen) efficacy and harm: Systematic review and meta-analysis Published in Canadian Family Physician, July 2025 Developing Community Pharmacist Prescribing Models to Expand Access to Medications for Opioid Use Disorder Published in the Journal of Addiction Medicine, September 2025 Children's Experiences of Parental Deaths Due to Suicide, Homicide, Overdose, Alcohol, or Drug Use Published in JAMA Network Open, September 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing long-term outcomes of non-surgical treatments for chronic low back pain, cognition- and stress-targeted therapies for chronic whiplash, how challenging clinical encounters may influence pain outcomes, and more! Long-term effectiveness of non-surgical interventions for chronic low back pain: a systematic review and meta-analysis Published in Lancet Rheumatology, September 2025 Pain Science Education, Stress Management, and Cognition-Targeted Exercise Therapy in Chronic Whiplash Disorders A Randomized Clinical Trial Published in JAMA Network Open, August 2025 Do difficult encounters affect pain treatment outcomes? A prospective cohort study Published in Pain Medicine, September 2025 Rural providers' attitudes toward integrating harm reduction strategies and PrEP prescribing into rural primary care settings in the US. Southeast and Midwest Published in Addiction Science and Clinical Practice, September 2025 Addiction Consult Services, Mortality, and Acute Care Utilization in Inpatients With Opioid Use Disorder A Secondary Analysis of a Cluster Randomized Clinical Trial Published in JAMA Network Open, August 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing telehealth and online CBT-based therapies for high-impact chronic pain, the pain benefits of sleep-focused interventions in fibromyalgia, pharmacy barriers to buprenorphine access in telemedicine-based addiction care, and more! Telehealth and Online Cognitive Behavioral Therapy–Based Treatments for High-Impact Chronic Pain A Randomized Clinical Trial Published in JAMA, July 2025 Minor tranquillizers for short-term treatment of newly onset symptoms of anxiety and distress: a systematic review with network meta-analysis of randomized trials Published in the European Archives of Psychiatric and Clinical Neuroscience, August 2023 Analgesic benefits of pharmacological and nonpharmacological sleep interventions for adults with fibromyalgia: a systematic review and meta-analyses Published in Pain, July 2025 Pharmacy Barriers to Receiving Buprenorphine Among Patients Undergoing Telemedicine Addiction Treatment Published in JAMA Network Open, August 2025 Pregabalin for Chronic Noncancer Pain—When Pain Relief Comes at a Cardiac Cost Published in JAMA Network Open, August 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing patterns of usual low back pain management in U.S. emergency departments, quality improvement approaches to safer postoperative opioid use, updated clinical guidelines for treating substance use disorders in adolescents and young adults, and more! Usual Care for Low Back Pain at United States Emergency Departments, 2016-2022 Published in Annals of Emergency Medicine, July 2025 Improving pain management and safe opioid use after surgery: A DMAIC-based quality intervention Published in Surgery Open Science, June 2023 Safety and Efficacy of Platelet-Rich Plasma versus Genicular Nerve Radiofrequency Ablation in Knee Osteoarthritis: An Open-Label, Prospective, Randomized, Clinical Trial Published in Pain Physician, May 2025 Clinical Practice Guideline: Assessment and Treatment of Adolescents and Young Adults With Substance Use Disorders and Problematic Substance Use (Excluding Tobacco) Published in the Journal of American Academy of Child and Adolescent Psychiatry, August 2025 Hospital-Based Methadone and Buprenorphine Initiation Practices by Addiction Consult Services Published in JAMA Network Open, June 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing highlights from the 2024 National Survey on Drug Use and Health, opioid-free postoperative analgesia strategies, evidence for a prescribed digital health app reducing migraine days, low-threshold injectable buprenorphine initiation protocols, and more! Highlights for the 2024 National Survey on Drug Use and Health Published by SAMHSA, June 2025 Opioid-free strategies for patient-controlled intravenous postoperative analgesia: a review of recent studies Published in Frontiers in Pharmacology, October 2024 A Prescribed Digital Health App and Number of Migraine Days Published in JAMA, July 2025 Injectable-Only Overlapping Buprenorphine Starting Protocol in a Low-Threshold Setting Published in JAMA Network Open, June 2025 Initiation and Dose of Methadone Monotherapy vs Combination Therapy, 2015 to 2023 Published in JAMA Network Open, August 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing public awareness and beliefs about naloxone, benzodiazepine use and adverse outcomes among patients on long-term opioid therapy, the relationship between pain and cannabis initiation in emerging adults, racial and ethnic differences in access to OUD treatment after emergency department visits, and more! Awareness of and Beliefs About Naloxone Among Adults, Published in JAMA Health Forum, June 2025 Correlates of Benzodiazepine Use and Adverse Outcomes Among Patients with Chronic Pain Prescribed Long-term Opioid Therapy, Published in Pain Medicine, June 2019 Pain Predicts Cannabis Initiation Among Emerging Adults: Results from the Population Assessment of Tobacco and Health (PATH) Study, Published in Behavioral Medicine, July 2025 Racial and Ethnic Factors and Opioid Use Disorder Treatment After an Emergency Department Visit, Published in JAMA Network Open, July 2025 Gabapentin Use Linked to Increased Dementia Risk in Patients With Chronic Back Pain, Published in Pharmacy Times, July 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing risks of benzodiazepines and other sedative-hypnotics, overdose risk from overlapping opioid and benzodiazepine prescriptions, non-procedural treatments for peripheral neuropathic pain, NSAIDs as effective alternatives to opioids for postoperative pain, and rising emergency department visits for cannabis hyperemesis syndrome among adolescents. Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis Published in BMJ, June 2025 Association Between Receipt of Overlapping Opioid and Benzodiazepine Prescriptions From Multiple Prescribers and Overdose Risk Published in JAMA Network Open, August 2021 An overview of the non-procedural treatment options for peripheral neuropathic pain Published in Muscle and Nerve, May 2025 Randomized Controlled Trial of Nonsteroidal Anti-Inflammatory Drugs as a Safe and Effective Alternative to Opioids for Pain Relief Following Percutaneous Nephrolithotomy Published in the Journal of Endourology, July 2025 Emergency Department Visits for Cannabis Hyperemesis Syndrome Among Adolescents Published in JAMA Network Open, July 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing updated guidance on long-term opioid therapy for nonterminal pain, patterns of high-risk outpatient opioid prescribing, evidence for open-label placebo effects in chronic musculoskeletal pain, links between addictive screen use and youth mental health and suicidality, and more! Long-Term Opioid Therapy for Nonterminal Pain Published in American Family Physician, June 2025 High-risk opioid prescribing trends in the outpatient setting prior to issuance of federal guidance Published Preventative Medicine Reports, September 2019 A systematic review and meta analysis of open label placebo effects in chronic musculoskeletal pain Published in Scientific Reports, July 2025 Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths Published in JAMA, July 2025 Use of Tobacco and Cannabis Following State-Level Cannabis Legalization Published in JAMA Network Open, July 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing new evidence on cytisinicline for smoking cessation, links between sedentary behavior and brain health in older adults, factors affecting exercise adherence in chronic low back pain, national trends in postoperative opioid prescribing and persistent use, and, and more! Cytisinicline for Smoking Cessation The ORCA Phase 3 Replication Randomized Clinical Trial Published in JAMA Internal Medicine, April 2025 Sedentary Time Tied to Brain Volume, Worse Cognition in Older Adults Published in MedPage Today, May 2025 Barriers and enablers to exercise adherence in people with nonspecific chronic low back pain: a systematic review of qualitative evidence Published in Pain, October 24 Trends in Opioid Prescribing and New Persistent Opioid Use After Surgery in the United States Published in Annals of Surgery, March 2025 Prevalence of Impairing Substance Use in Injured Drivers Published in JAMA Network Open, April 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing online DBT for chronic pain, national trends in overdose deaths, the effects of exercise on brain activation in osteoarthritis, and more! Online Dialectical Behavioral Therapy for Emotion Dysregulation in People With Chronic Pain A Randomized Clinical Trial Published in JAMA Network, May 2025 US overdose deaths fell 27% last year, the largest one-year decline ever seen Published in AP News, May 2025 Changes in prefrontal cortex activation with exercise in knee osteoarthritis patients with chronic pain: An fNIRS study Published in the Journal of Clinical Neuroscience, August 2021 The impact of change in regulations on buprenorphine prescribing for opioid use disorder Published in the American Journal of Health-System Pharmacy, March 2025 Alcohol Use Disorder Diagnoses Among Individuals Who Take HIV Preexposure Prophylaxis Published in JAMA Network, April 2025

Episode 73 In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the link between pain catastrophizing and metabolic syndrome, changes in synthetic opioid-involved youth overdoses, the effect of aerobic exericse on pain, and more!  Receipt of addiction treatment after nonfatal opioid overdose and risk of subsequent overdose: A retrospective cohort study Published in Science Direct, August 2025  Metabolic Syndrome Increases Pain Catastrophizing in Psoriatic Arthritis, Published in Rheumatology Advisor, May 2025  Effect of Aerobic Exercise on the Levels of Pain, Quality of Life, and Alexithymia in Alexithymic Individuals With Chronic Pain: A Single-Blinded Randomized Controlled Trial, Published in the Journal of Manipulative and Physiological Therapeutics, June 2023  Changes in Synthetic Opioid–Involved Youth Overdose Deaths in the United States: 2018–2022 Published in Pediatrics, May 2025  Volume and Intensity of Walking and Risk of Chronic Low Back Pain, Published in JAMA Network Open, June 2025 

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing oral vs injectable naltrexone, brain function outcomes in long term heavy cannabis use, and more!  Oral vs Extended-Release Injectable Naltrexone for Hospitalized Patients With Alcohol Use Disorder A Randomized Clinical Trial, Published in JAMA Internal Medicine, April 2025 Degenerative Disc Disease In Young Adults With Psoriatic Arthritis, Published in the Journal of Rheumatology, February 2025 Short-term impact of combining pain neuroscience education with exercise for chronic musculoskeletal pain: a systematic review and meta-analysis, Published in Pain, January 2022 Empowering Pharmacists: Strategies for Addressing the Opioid Crisis through a Public Health Lens, Published in Pharmacy, May 2024 Brain Function Outcomes of Recent and Lifetime Cannabis Use, Published in JAMA Network Open, January 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the link between dietary fiber intake and osteoarthritis, buprenorphine induction in pharmacies, and more!  Trajectories of mHealth-Tracked Mental Health and Their Predictors in Female Chronic Pelvic Pain Disorders, Published in the Journal of Pain Research, November 2024 The association between dietary fiber intake and osteoarthritis: a cross-sectional study from the 1999–2018 U.S. National Health and Nutrition Examination Survey, Published in the Journal of Orthopaedic Surgery and Research, February 2025 The influence of exercise on pain, disability and quality of life in office workers with chronic neck pain: A systematic review and meta-analysis, Published in Applied Ergonomics, May 2024 Physician-Delegated Unobserved Induction with Buprenorphine in Pharmacies, Published in the New England Journal of Medicine, January 2023 Cannabis Use Among Older Adults, Published in JAMA Network Open, May 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing mindfulness vs CBT, the impact of home exercise training for low back pain, and more!  Mindfulness vs Cognitive Behavioral Therapy for Chronic Low Back Pain Treated With Opioids A Randomized Clinical Trial, Published in JAMA Network Open, April 2025 Therapeutic effects of turmeric or curcumin extract on pain and function for individuals with knee osteoarthritis: a systematic review, Published in BMJ Open Sport & Exercise Medicine, January 2021 Effect of Home Exercise Training in Patients with Nonspecific Low-Back Pain: A Systematic Review and Meta-Analysis, Published in the International Journal of Environmental Research and Public Health, August 2021 Piloting an opioid callback program in community pharmacies, Published in the Journal of the American Pharmacists Association, November-December 2023 Loss of Medicaid and Treatment of Opioid Use Disorder, Published by JAMA Network Open, May 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the new joint clinical practice guideline on benzodiazepine tapering, myofascial pain syndrome, dietary modification and supplement use for endometriosis, and more!  The Joint Clinical Practice Guideline on Benzodiazepine Tapering: Considerations When Benzodiazepine Risks Outweigh Benefits, Published by the American Society of Addiction Medicine, February 2025 Discrimination, Depression, and Anxiety Among US Adults, Published by JAMA Network Open, March 2025 Myofascial Pain Syndrome: An Update on Clinical Characteristics, Etiopathogenesis, Diagnosis, and Treatment, Published by Muscle & Nerve, May 2025 A multi-method spatial examination of factors associated with changes in geographic accessibility to buprenorphine providers in HEALing communities study states Kentucky, Massachusetts, and Ohio, Published by Preventative Medicine Reports, May 2025 Dietary Modification and Supplement Use For Endometriosis Pain, Published in JAMA Network Open, March 2025

In this episode, Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing acute pain management in patients with OUD, trends in buprenorphine prescribing for chronic pain, the association between fiber intake and osteoarthritis, and more!  Acute Pain Management in People With Opioid Use Disorder: A Systematic Review, Published in the Annals of Internal Medicine, March 2025 The association between dietary fiber intake and osteoarthritis: a cross-sectional study from the 1999–2018 U.S. National Health and Nutrition Examination Survey, Published in Journal of Orthopaedic Surgery and Research, February 2025 Personalised decision support in the management of patients with musculoskeletal pain in primary physiotherapy care: a cluster randomised controlled trial (the SupportPrim project), Published in Pain, May 2025 Trends in Outpatient Buprenorphine Prescribing for Chronic Pain: A Retrospective Analysis Over 18 Months, Published in Psychopharmacology Bulletin, April 2025 Hospital Security Searches Among Patients With Substance-Related Encounters, Published in JAMA Network Open, March 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing non-pharmacologic interventions for pain, expansion of treatment for AUD in primary care, prescribing of buprenorphine by pharmacists, and more!  Expanding Alcohol Use Disorder Medications in Primary Care, Published in JAMA Internal Medicine, March 2025 Nonfatal pediatric fentanyl exposures reported to US poison centers, 2015–2023, Published in the American Journal of Drug and Alcohol Abuse, November 2024 An update on non-pharmacological interventions for pain relief, Published in Cell Reports Medicine, February 2025 Clinical pharmacist practitioners prescribing of buprenorphine for opioid use disorder, Published in Drug and Alcohol Dependence, March 2025 Law Enforcement Drug Seizures and Opioid-Involved Overdose Mortality, Published in JAMA Network Open, March 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the analgesic benefits of nature exposure, fatal drug overdoses in healthcare workers, and more!  Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids: A Randomized Clinical Trial, Published in JAMA Internal Medicine, February 2025 Prevalence of Depression and Anxiety Among Adults With Chronic Pain A Systematic Review and Meta-Analysis, Published in JAMA Network Open, March 2025 Nature exposure induces analgesic effects by acting on nociception-related neural processing, Published in Nature Communications, March 2025 Buprenorphine-naloxone versus buprenorphine for opioid use disorder during pregnancy: A systematic review and meta-analysis, Published in the Journal of Addiction Medicine, November/December 2022 Fatal Drug Overdose Risks of Health Care Workers in the United States : A Population-Based Cohort Study, Published in the Annals of Internal Medicine, August 2023

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the new NIH HEAL MME Calculator, the recent consensus statement on pain management for pregnant individuals with OUD, and more!  Standardizing research methods for opioid dose comparison: the NIH HEAL morphine milligram equivalent calculator, Published in PAIN, February 2025 Occupational and Hobby Exposures Associated With Myositis Phenotypes in a National Myositis Patient Registry, Published in Arthritis Care and Research, November 2024 Problem Adaptation Therapy for Older Adults with Chronic Pain and Negative Emotions in Primary Care (PATH-Pain): A Randomized Clinical Trial, Published in the American Journal of Geriatric Psychiatry, January 2025 Consensus statement on pain management for pregnant patients with opioid use disorder from the Society for Obstetric Anesthesia and Perinatology, Society for Maternal-Fetal Medicine, and American Society of Regional Anesthesia and Pain Medicine, Published in Anesthesia and Analgesia, November 2024 Access to Firearms and Opioids Among Veterans at Risk for Suicide, Published in JAMA Network Open, January 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing depression and physical multimorbidity, pharmacy harm reduction practices, new persistent opioid use after surgery, and more!  Racial and Ethnic Inequities in the Receipt of Medications to Treat Opioid Use Disorder Among Pregnant People: A Meta-analysis, Published in the Journal of Addiction Medicine, February 2025 Depression and physical multimorbidity: A cohort study of physical health condition accrual in UK Biobank, Published in PLOS Medicine, February 2025 Comparative Effectiveness of Different Opioid Regimens, in Daily Dose or Treatment Duration, Prescribed at Surgical Discharge: a Systematic Review and Meta‐Analysis, Published in CNS Drugs, April 2025 Pharmacy Harm Reduction Practices to Help Reduce Opioid Overdoses, Arizona 2023, Published in the Journal of the American Pharmacists Association, April 2025 New Persistent Opioid Use After Surgery, Published in JAMA Network Open, February 2025  

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing physician empathy and the impact on pain perception, esketamine for prevention of postpartum depression, and more!  Mindfulness Training vs Recovery Support for Opioid Use, Craving, and Anxiety During Buprenorphine Treatment: A Randomized Clinical Trial, Published in JAMA Network Open, January 2025 Do individuals with inflammatory arthritis receive minimally adequate treatment for incident depression and anxiety: A population-based study, Published in Arthritis Research and Therapy, January 2025 Physician Empathy and Chronic Pain Outcomes, Published in JAMA Network Open, April 2024 Navigating Buprenorphine Therapy: A Closer Look at Microdosing vs. Macrodosing for Pain Management and Opioid Addiction - A Narrative Review, Published in Addiction Health, October 2024 Intraoperative Esketamine and Postpartum Depression Among Women With Cesarean Delivery: A Randomized Clinical Trial, Published in Jama Network Open, February 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing risks of opioid tapering, a novel artery procedure for knee arthritis, and more!  Association of opioid tapering with pain-related emergency department visits, hospitalizations, and primary care visits: a retrospective cohort study, Published in Pain Medicine, November 2024 Artery Procedure May Offer Surgery-Free Way to Ease Knee Arthritis, Published in Health Day, December 2024 Clinical and Mental Health Characteristics Among Patients Receiving Medications for OUD Treatment vs High-Dose Opioids When Referred for Pain Management, Published in Pain Medicine, February 2025 Substance Use Disorder and Harm Reduction Curriculum in United States and Canadian Undergraduate Medical Education: An Online Survey, Published in Amersa, February 2025 Rest-Activity Rhythms, Their Modulators, and Brain-Clinical Correlates in Opioid Use Disorder, Published in JAMA Network Open, February 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing Journavx (suzetrigine), recommendations for vitamin D and calcium supplementation, perioperative use of tapentadol, and more!  FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain, Published as an FDA News Release, January 2025 Vitamin D, Calcium, or Combined Supplementation for the Primary Prevention of Falls and Fractures in Community-Dwelling Adults: Preventive Medication, Published by the U.S. Preventive Services Task Force, December 2024 Considerations for perioperative opioid analgesic stewardship in Australia: a focus on tapentadol, Published in Pain Management, June 2023 The Overdose Crisis among U.S. Adolescents, Published in the New England Journal of Medicine, January 2024 Mortality Trends Among Early Adults in the United States, 1999-2023, Published in JAMA Network Open, January 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing chronic pelvic pain syndrome in men, long-term effects of muscle relaxants, and more!  Chronic Pain and High-impact Chronic Pain in U.S. Adults, 2023, Published by the National Center for Health Statistics Data Brief, Number 518, November 2024 Examining social attention as a predictor of problem drinking behavior: A longitudinal study using eye-tracking, Published in Alcohol- Clinical and Experimental Research, December 2024 Experiences of pain debut and healthcare received in men with chronic pelvic pain syndrome, Published in BMC Urology, June 2023 Evaluation of a Program Designed to Support Implementation of Prescribing Medication for Treatment of Opioid Use Disorder in Primary Care Practices, Published in the Annals of Family Medicine, January 2025 Long-Term Use of Muscle Relaxant Medications for Chronic Pain A Systematic Review, Published in JAMA Network Open, September 2024

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the effects of long-term kratom use, hand osteoarthritis, insomnia in older adults, and more!  The Unregulated Opioid: Neurologic and Electrolyte Imbalance From Long-Term Kratom Use, Published in the Annals of Internal Medicine- Clinical Cases, January 2025 Course of hand pain over four years in patients with hand osteoarthritis depends on BMI, employment and mental wellbeing: The Hand OSTeoArthritis in Secondary care cohort study, Published in Arthritis Care and Research, December 2024 Insomnia in older adults: A review of treatment options, Published in the Cleveland Clinic Journal of Medicine, January 2025 Ketamine Infusion for Complex Regional Pain Syndrome Treatment: A Narrative Review, Published in Anesthesiology Clinical, April 2023 Trends in Treatment Need and Receipt for Substance Use Disorders in the US, Published in JAMA Network Open, January 2025

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing the link between Vitamin D levels and migraines, methotrexate for knee osteoarthritis, and more!  Trends in Private Equity Acquisition of Pain Management Practices, Published in JAMA, December 2024 Association between serum vitamin D and severe headache or migraine: A population-based analysis, Published in PLoS One, January 2025 Pain Reduction With Oral Methotrexate in Knee Osteoarthritis: A Randomized, Placebo-Controlled Clinical Trial, Published in the Annals of Internal Medicine, July 2024 A cross-sectional study of differences in medication for opioid use disorder receipt among pregnant people enrolled in Medicaid in Oregon, United States, Published in Addiction, January 2025 Healthy Lifestyle Care vs Guideline-Based Care for Low Back Pain A Randomized Clinical Trial, Published in JAMA Network Open, January 2025

In this episode, Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing persistent pain and long-term opioids, safer opioid supply programs, suicide risk in patients prescribed opioid agonist therapy, and more!  Suicide in people prescribed opioid-agonist therapy in Scotland, United Kingdom, 2011–2020: A national retrospective cohort study, Published in Addiction, May 2024 Persistent pain, long-term opioids, and restoring trust in the patient-clinician relationship, Published in the Journal of Pain, October 2024 Implementation and Enforcement of State Opioid Prescribing Laws, Published in Drug and Alcohol Dependence, August 2021 Safer Opioid Supply programs: Hydromorphone prescribing in Ontario as a harm reduction intervention to combat the drug poisoning crisis, Canadian Journal of Public Health, December 2024 Amygdala Cannabinoid 1 Receptor, Pain Response, and Emotional Numbing in Trauma-Exposed Individuals, Published in JAMA Network Open, September 2024  

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing opioids and dementia risk, bending the overdose curve, extended release naltrexone, and more!  Opioids and Dementia in the Danish Population, Published in JAMA Network Open, November 2024 Bending the Overdose Curve — Still Not Enough | New England Journal of Medicine, published in the New England Journal of Medicine, September 2024 Opioid Prescribing Patterns After Imposition of Setting-Specific Limits on Prescription Duration, Published in JAMA Health Forum, January 2024 Follow-up and reasons for extended-release naltrexone discontinuation for alcohol use disorder after hospital initiation, Published in the BMJ, December 2024 Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge, Published in JAMA Network Open, March 2024

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks discussing pain neuroscience education, CBT for insomnia in chronic spinal pain patients, and more!  Masked Taper With Behavioral Intervention for Discontinuation of Benzodiazepine Receptor Agonists: A Randomized Clinical Trial, Published in JAMA, October 2024 Screened Out — How a Survey Change Sheds Light on Iatrogenic Opioid Use Disorder | New England Journal of Medicine, Published in the New England Journal of Medicine, November 2024 Care Models to Improve Pain and Reduce Opioids Among Patients Prescribed Long-Term Opioid Therapy: The VOICE Randomized Clinical Trial, Published in JAMA Internal Medicine, December 2024 Effect of pain neuroscience education+ (PNE+) in people with different mechanisms of chronic pain: A systematic review and meta-analysis, Published in the Journal of Bodywork and Movement Therapies, November 2024 Cognitive Behavioral Therapy for Insomnia in Pain Management for Nonspecific Chronic Spinal Pain: A Randomized Clinical Trial, Published in JAMA Network Open, August 2024

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing TENS for knee osteoarthritis, buprenorphine continuation in the peri-operative period, combination therapy for neuropathic pain, and more!  The association between glucose-dependent insulinotropic polypeptide and/or glucagon-like peptide-1 receptor agonist prescriptions and substance-related outcomes in patients with opioid and alcohol use disorders: A real-world data analysis, Published in Addiction, October 2024 Combination Drug Therapy for the Management of Chronic Neuropathic Pain, Published in Biomolecules, December 2023 Effect of transcutaneous electrical nerve stimulation (TENS) on kneepain and physical function in patients with symptomatic knee osteoarthritis: the ETRELKA randomized clinical trial, Published in Osteoarthritis and Cartilage, March 2022 Continuation versus Interruption of Buprenorphine/Naloxone in Adult Veterans Undergoing Surgery: Examination of Postoperative Pain and Opioid Utilization in a National Retrospective Cohort Study, Published in Anesthesiology, November 2024 Prison Buprenorphine Implementation and Postrelease Opioid Use Disorder Outcomes, Published in JAMA Network Open, March 2024

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing Nav1.7 for osteoarthritis, resistance exercise for fibromyalgia, virtual yoga for chronic low back pain , and more!  Buprenorphine/Naloxone vs Methadone for the Treatment of Opioid Use Disorder, Published in JAMA, October 2024 Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis, Published in Nature, January 2024 Dosage of resistance exercises in fibromyalgia: evidence synthesis for a systematic literature review up‐date and meta‐analysis, Published in Rheumatology International, March 2022 A Hospital-Based Intervention to Improve Access to Buprenorphine for Patients with Opioid Use Disorder, Published in Substance Use and Addiction Journal, November 2024 Effectiveness of Virtual Yoga for Chronic Low Back Pain A Randomized Clinical Trial, Published in JAMA Network Open, November 2024

In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing buprenorphine associated precipitated withdrawal, open label placebo injections, the potential use of GLP-1 RA's in SUD, and more!  Open-Label Placebo Injection for Chronic Back Pain With Functional Neuroimaging: A Randomized Clinical Trial, Published in JAMA Network Open, September 2024 The Efficacy of GLP-1 Agonists in Treating Substance Use Disorder in Patients: A Scoping Review, Published in the Journal of Addiction Medicine, Sept/Oct 2024 Back and neck pain: in support of routine delivery of non-pharmacologic treatments as a way to improve individual and population Health, Published in Translational Research, August 2021 Management of patients at risk of harms from both continuing and discontinuing their long-term opioid therapy: A qualitative study to inform the gap in clinical practice guidelines, Published in Pain Practice, November 2024 Buprenorphine-Precipitated Withdrawal Among Hospitalized Patients Using Fentanyl, Published in JAMA Network Open, September 2024

 In this episode Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing pregabalin versus gabapentin in lumbar radiculopathy, outcomes of placebo treatment in psychiatric disorders, illicit fentanyl during the prenatal period, and more!  Comparing the effectiveness of pregabalin and gabapentin in patients with lumbar radiculopathy: A systematic review and meta-analysis, Published in Pain Practice, October 2024 Open-label, rapid initiation pilot study for extended-release buprenorphine subcutaneous injection - PubMed , Published in the American Journal of Drug and Alcohol Abuse, January 2023 Differential Outcomes of Placebo Treatment Across 9 Psychiatric Disorders A Systematic Review and Meta-Analysis, Published in JAMA, May 2024 Illicit Fentanyl in the Prenatal Period: A Significant Emerging Risk for Neonatal Opioid Withdrawal Syndrome, Published in the American Journal of Perinatology, October 2024 Comparative Safety of In Utero Exposure to Buprenorphine Combined With Naloxone vs Buprenorphine Alone, Published in JAMA

In this episode, Dr. Stader and Dr. Bradley summarize and offer key insights for the following Coaches Top 5 picks, discussing extended-release injectable buprenorphine versus sublingual, mortality association with benzodiazepine and opioid agonist co-prescribing, and more!  Buprenorphine Prescribing Characteristics Following Relaxation of X-Waiver Training Requirements, Published in JAMA, July 2024 Extended-Release Injection vs Sublingual Buprenorphine for Opioid Use Disorder With Fentanyl Use A Post Hoc Analysis of a Randomized Clinical Trial, Published in JAMA, June 2024 Empowered Relief, cognitive behavioral therapy, and health education for people with chronic pain: a comparison of outcomes at 6-month Follow-up for a randomized controlled trial, Published in Pain Reports, Jan 2024 The association between benzodiazepine co-prescription, opioid agonist treatment and mortality: a systematic review, Published in BMC Psychiatry, October 2024 Rapid Initiation of Injection Naltrexone for Opioid Use Disorder, Published by JAMA, May 2024